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Glutathione S-transferase (EC 2.5.1.18) (Fragments)

 Q7M0F4_MOUSE            Unreviewed;       142 AA.
Q7M0F4;
15-DEC-2003, integrated into UniProtKB/TrEMBL.
15-DEC-2003, sequence version 1.
25-OCT-2017, entry version 67.
RecName: Full=Glutathione S-transferase {ECO:0000256|RuleBase:RU003494};
EC=2.5.1.18 {ECO:0000256|RuleBase:RU003494};
Flags: Fragments;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090 {ECO:0000313|PIR:S17462};
[1] {ECO:0000313|PIR:S17462}
PROTEIN SEQUENCE.
PubMed=1859377;
Hayes J.D., Kerr L.A., Peacock S.D., Cronshaw A.D., McLellan L.I.;
"Hepatic glutathione S-transferases in mice fed on a diet containing
the anticarcinogenic antioxidant butylated hydroxyanisole. Isolation
of mouse glutathione S-transferase heterodimers by gradient elution of
the glutathione-Sepharose affinity matrix.";
Biochem. J. 277:501-512(1991).
-!- CATALYTIC ACTIVITY: RX + glutathione = HX + R-S-glutathione.
{ECO:0000256|RuleBase:RU003494}.
-!- SIMILARITY: Belongs to the GST superfamily. Mu family.
{ECO:0000256|RuleBase:RU003494}.
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PIR; S17462; S17462.
PeptideAtlas; Q7M0F4; -.
HOVERGEN; HBG106842; -.
GO; GO:0004364; F:glutathione transferase activity; IEA:UniProtKB-EC.
GO; GO:0008152; P:metabolic process; IEA:InterPro.
InterPro; IPR010987; Glutathione-S-Trfase_C-like.
InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
InterPro; IPR004045; Glutathione_S-Trfase_N.
InterPro; IPR004046; GST_C.
InterPro; IPR003081; GST_mu.
InterPro; IPR036249; Thioredoxin-like_sf.
Pfam; PF00043; GST_C; 1.
Pfam; PF02798; GST_N; 1.
PRINTS; PR01267; GSTRNSFRASEM.
SUPFAM; SSF47616; SSF47616; 1.
SUPFAM; SSF52833; SSF52833; 1.
PROSITE; PS50405; GST_CTER; 1.
PROSITE; PS50404; GST_NTER; 1.
3: Inferred from homology;
Transferase {ECO:0000256|RuleBase:RU003494}.
DOMAIN 1 88 GST N-terminal.
{ECO:0000259|PROSITE:PS50404}.
DOMAIN 36 142 GST C-terminal.
{ECO:0000259|PROSITE:PS50405}.
NON_TER 1 1 {ECO:0000313|PIR:S17462}.
NON_TER 142 142 {ECO:0000313|PIR:S17462}.
SEQUENCE 142 AA; 16784 MW; 53353B7B05C45167 CRC64;
PMTLGYWDIR GLAHAIRLLL EYTDTSYEDK KYTMGDAPDY DRSQWLSEKF KLGLDFPNLP
YLIDGMDTXI QLAMVXYSPD FEKKKPEYLE GLPEKMKLYS EFLGKQPWFA GNKVTYVDFL
VYDVLDQHMK SSRFLMAFWN PK


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