Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Glutathione S-transferase Mu 2 (EC 2.5.1.18) (GST 5-5) (GST class-mu 2) (Glutathione S-transferase pmGT2)

 GSTM2_MOUSE             Reviewed;         218 AA.
P15626;
01-APR-1990, integrated into UniProtKB/Swiss-Prot.
23-JAN-2007, sequence version 2.
12-SEP-2018, entry version 158.
RecName: Full=Glutathione S-transferase Mu 2;
EC=2.5.1.18;
AltName: Full=GST 5-5;
AltName: Full=GST class-mu 2;
AltName: Full=Glutathione S-transferase pmGT2;
Name=Gstm2;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
PubMed=2689439;
Townsend A.J., Goldsmith M.E., Pickett C.B., Cowan K.H.;
"Isolation, characterization, and expression in Escherichia coli of
two murine Mu class glutathione S-transferase cDNAs homologous to the
rat subunits 3 (Yb1) and 4 (Yb2).";
J. Biol. Chem. 264:21582-21590(1989).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=129/SvJ;
PubMed=11404019; DOI=10.1016/S0378-1119(01)00473-5;
Kumar A., Reddy E.P.;
"Genomic organization and characterization of the promoter region of
murine GSTM2 gene.";
Gene 270:221-229(2001).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=FVB/N; TISSUE=Colon;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[4]
PROTEIN SEQUENCE OF 2-25.
PubMed=8442656; DOI=10.1006/abbi.1993.1126;
Awasthi S., Singhal S.S., Srivastava S.K., Awasthi Y.C.;
"Purification and characterization of glutathione S-transferase of
murine ovary and testis.";
Arch. Biochem. Biophys. 301:143-150(1993).
[5]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-117, AND IDENTIFICATION
BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung,
Pancreas, Spleen, and Testis;
PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
"A tissue-specific atlas of mouse protein phosphorylation and
expression.";
Cell 143:1174-1189(2010).
-!- FUNCTION: Conjugation of reduced glutathione to a wide number of
exogenous and endogenous hydrophobic electrophiles.
-!- CATALYTIC ACTIVITY: RX + glutathione = HX + R-S-glutathione.
-!- SUBUNIT: Homodimer.
-!- SUBCELLULAR LOCATION: Cytoplasm.
-!- SIMILARITY: Belongs to the GST superfamily. Mu family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; J04696; AAA37706.1; -; mRNA.
EMBL; AF319526; AAK28508.1; -; Genomic_DNA.
EMBL; BC037068; AAH37068.1; -; mRNA.
CCDS; CCDS17746.1; -.
PIR; B34159; B34159.
RefSeq; NP_032209.1; NM_008183.3.
UniGene; Mm.440086; -.
ProteinModelPortal; P15626; -.
SMR; P15626; -.
BioGrid; 200095; 1.
IntAct; P15626; 4.
MINT; P15626; -.
STRING; 10090.ENSMUSP00000012348; -.
iPTMnet; P15626; -.
PhosphoSitePlus; P15626; -.
REPRODUCTION-2DPAGE; IPI00228820; -.
REPRODUCTION-2DPAGE; P15626; -.
SWISS-2DPAGE; P15626; -.
MaxQB; P15626; -.
PaxDb; P15626; -.
PeptideAtlas; P15626; -.
PRIDE; P15626; -.
Ensembl; ENSMUST00000012348; ENSMUSP00000012348; ENSMUSG00000040562.
GeneID; 14863; -.
KEGG; mmu:14863; -.
UCSC; uc008qxw.1; mouse.
CTD; 2946; -.
MGI; MGI:95861; Gstm2.
eggNOG; ENOG410IN5J; Eukaryota.
eggNOG; ENOG4110YU0; LUCA.
GeneTree; ENSGT00550000074559; -.
HOGENOM; HOG000115735; -.
HOVERGEN; HBG106842; -.
InParanoid; P15626; -.
KO; K00799; -.
OMA; YWDIRGR; -.
OrthoDB; EOG091G0K2E; -.
PhylomeDB; P15626; -.
TreeFam; TF353040; -.
Reactome; R-MMU-156590; Glutathione conjugation.
PRO; PR:P15626; -.
Proteomes; UP000000589; Chromosome 3.
Bgee; ENSMUSG00000040562; Expressed in 281 organ(s), highest expression level in testis.
CleanEx; MM_GSTM2; -.
ExpressionAtlas; P15626; baseline and differential.
Genevisible; P15626; MM.
GO; GO:0005737; C:cytoplasm; ISO:MGI.
GO; GO:0005829; C:cytosol; ISO:MGI.
GO; GO:0045171; C:intercellular bridge; ISO:MGI.
GO; GO:0005886; C:plasma membrane; ISO:MGI.
GO; GO:0032991; C:protein-containing complex; ISO:MGI.
GO; GO:0019899; F:enzyme binding; ISO:MGI.
GO; GO:0043295; F:glutathione binding; ISO:MGI.
GO; GO:0004364; F:glutathione transferase activity; IDA:MGI.
GO; GO:0046982; F:protein heterodimerization activity; IDA:MGI.
GO; GO:0042803; F:protein homodimerization activity; IDA:MGI.
GO; GO:0070458; P:cellular detoxification of nitrogen compound; ISO:MGI.
GO; GO:0006749; P:glutathione metabolic process; ISO:MGI.
GO; GO:0018916; P:nitrobenzene metabolic process; ISO:MGI.
GO; GO:0042178; P:xenobiotic catabolic process; ISO:MGI.
InterPro; IPR010987; Glutathione-S-Trfase_C-like.
InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
InterPro; IPR004045; Glutathione_S-Trfase_N.
InterPro; IPR004046; GST_C.
InterPro; IPR003081; GST_mu.
InterPro; IPR036249; Thioredoxin-like_sf.
Pfam; PF00043; GST_C; 1.
Pfam; PF02798; GST_N; 1.
PRINTS; PR01267; GSTRNSFRASEM.
SUPFAM; SSF47616; SSF47616; 1.
SUPFAM; SSF52833; SSF52833; 1.
PROSITE; PS50405; GST_CTER; 1.
PROSITE; PS50404; GST_NTER; 1.
1: Evidence at protein level;
Complete proteome; Cytoplasm; Direct protein sequencing;
Phosphoprotein; Reference proteome; Transferase.
INIT_MET 1 1 Removed. {ECO:0000269|PubMed:8442656}.
CHAIN 2 218 Glutathione S-transferase Mu 2.
/FTId=PRO_0000185827.
DOMAIN 2 88 GST N-terminal.
DOMAIN 90 208 GST C-terminal.
REGION 7 8 Glutathione binding.
{ECO:0000250|UniProtKB:P08010}.
REGION 43 46 Glutathione binding.
{ECO:0000250|UniProtKB:P08010}.
REGION 59 60 Glutathione binding.
{ECO:0000250|UniProtKB:P08010}.
REGION 72 73 Glutathione binding.
{ECO:0000250|UniProtKB:P08010}.
BINDING 50 50 Glutathione.
{ECO:0000250|UniProtKB:P08010}.
BINDING 116 116 Substrate. {ECO:0000250}.
MOD_RES 27 27 Phosphoserine.
{ECO:0000250|UniProtKB:P08010}.
MOD_RES 44 44 Phosphoserine.
{ECO:0000250|UniProtKB:P08010}.
MOD_RES 117 117 Phosphoserine.
{ECO:0000244|PubMed:21183079}.
SEQUENCE 218 AA; 25717 MW; 93D790DD75CBF51E CRC64;
MPMTLGYWDI RGLAHAIRLL LEYTDTSYED KKYTMGDAPD YDRSQWLSEK FKLGLDFPNL
PYLIDGSHKI TQSNAILRYL ARKHNLCGET EEERIRVDIL ENQAMDTRIQ LAMVCYSPDF
EKKKPEYLEG LPEKMKLYSE FLGKQPWFAG NKVTYVDFLV YDVLDQHRIF EPKCLDAFPN
LKDFMGRFEG LKKISDYMKS SRFLSKPIFA KMAFWNPK


Related products :

Catalog number Product name Quantity
U0609m CLIA Glutathione S-transferase A1,Glutathione S-transferase Ya,Glutathione S-transferase Ya1,GST class-alpha member 1,Gsta,Gsta1,Gstya,Mouse,Mus musculus 96T
E0609m ELISA kit Glutathione S-transferase A1,Glutathione S-transferase Ya,Glutathione S-transferase Ya1,GST class-alpha member 1,Gsta,Gsta1,Gstya,Mouse,Mus musculus 96T
E0609m ELISA Glutathione S-transferase A1,Glutathione S-transferase Ya,Glutathione S-transferase Ya1,GST class-alpha member 1,Gsta,Gsta1,Gstya,Mouse,Mus musculus 96T
U0609m CLIA Glutathione S-transferase A3,Glutathione S-transferase Ya3,Glutathione S-transferase Yc,GST class-alpha member 3,Gsta3,Gstyc,Mouse,Mus musculus 96T
E0609m ELISA kit Glutathione S-transferase A3,Glutathione S-transferase Ya3,Glutathione S-transferase Yc,GST class-alpha member 3,Gsta3,Gstyc,Mouse,Mus musculus 96T
E0609m ELISA Glutathione S-transferase A3,Glutathione S-transferase Ya3,Glutathione S-transferase Yc,GST class-alpha member 3,Gsta3,Gstyc,Mouse,Mus musculus 96T
E0609m ELISA kit Glutathione S-transferase A2,Glutathione S-transferase GT41A,GST class-alpha member 2,Gsta2,Mouse,Mus musculus 96T
U0609h CLIA Glutathione S-transferase A3,Glutathione S-transferase A3-3,GST class-alpha member 3,GSTA3,Homo sapiens,Human 96T
U0609h CLIA Glutathione S-transferase A5,Glutathione S-transferase A5-5,GST class-alpha member 5,GSTA5,Homo sapiens,Human 96T
E0609h ELISA kit Glutathione S-transferase A5,Glutathione S-transferase A5-5,GST class-alpha member 5,GSTA5,Homo sapiens,Human 96T
E0609h ELISA kit Glutathione S-transferase A4,Glutathione S-transferase A4-4,GST class-alpha member 4,GSTA4,Homo sapiens,Human 96T
E0609h ELISA Glutathione S-transferase A5,Glutathione S-transferase A5-5,GST class-alpha member 5,GSTA5,Homo sapiens,Human 96T
E0609m ELISA Glutathione S-transferase A2,Glutathione S-transferase GT41A,GST class-alpha member 2,Gsta2,Mouse,Mus musculus 96T
E0609h ELISA kit Glutathione S-transferase A3,Glutathione S-transferase A3-3,GST class-alpha member 3,GSTA3,Homo sapiens,Human 96T
U0609m CLIA Glutathione S-transferase A2,Glutathione S-transferase GT41A,GST class-alpha member 2,Gsta2,Mouse,Mus musculus 96T
E0609h ELISA Glutathione S-transferase A3,Glutathione S-transferase A3-3,GST class-alpha member 3,GSTA3,Homo sapiens,Human 96T
E0609h ELISA Glutathione S-transferase A4,Glutathione S-transferase A4-4,GST class-alpha member 4,GSTA4,Homo sapiens,Human 96T
U0609h CLIA Glutathione S-transferase A4,Glutathione S-transferase A4-4,GST class-alpha member 4,GSTA4,Homo sapiens,Human 96T
U0609m CLIA Glutathione S-transferase 5.7,Glutathione S-transferase A4,GST 5.7,GST A4-4,GST class-alpha member 4,Gsta,Gsta4,GSTA4-4,Mouse,Mus musculus 96T
E0609m ELISA kit Glutathione S-transferase 5.7,Glutathione S-transferase A4,GST 5.7,GST A4-4,GST class-alpha member 4,Gsta,Gsta4,GSTA4-4,Mouse,Mus musculus 96T
E0609m ELISA Glutathione S-transferase 5.7,Glutathione S-transferase A4,GST 5.7,GST A4-4,GST class-alpha member 4,Gsta,Gsta4,GSTA4-4,Mouse,Mus musculus 96T
U0609b CLIA Bos taurus,Bovine,Glutathione S-transferase A4,Glutathione S-transferase alpha-4,GST class-alpha member 4,GSTA4 96T
U0609b CLIA Bos taurus,Bovine,Glutathione S-transferase A2,Glutathione S-transferase alpha-2,GST class-alpha member 2,GSTA2 96T
U0609b CLIA Bos taurus,Bovine,Glutathione S-transferase A1,Glutathione S-transferase alpha-1,GST class-alpha member 1,GSTA1 96T
E0609b ELISA Bos taurus,Bovine,Glutathione S-transferase A1,Glutathione S-transferase alpha-1,GST class-alpha member 1,GSTA1 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur