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Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)]

 GDE_HUMAN               Reviewed;        1532 AA.
P35573; A6NCX7; A6NEK2; D3DT51; P78354; P78544; Q59H92; Q6AZ90;
Q9UF08;
01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
17-OCT-2006, sequence version 3.
25-OCT-2017, entry version 175.
RecName: Full=Glycogen debranching enzyme;
AltName: Full=Glycogen debrancher;
Includes:
RecName: Full=4-alpha-glucanotransferase;
EC=2.4.1.25;
AltName: Full=Oligo-1,4-1,4-glucantransferase;
Includes:
RecName: Full=Amylo-alpha-1,6-glucosidase;
Short=Amylo-1,6-glucosidase;
EC=3.2.1.33;
AltName: Full=Dextrin 6-alpha-D-glucosidase;
Name=AGL; Synonyms=GDE;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE (ISOFORM 5).
TISSUE=Muscle;
PubMed=1374391;
Yang B.-Z., Ding J.-H., Enghild J.J., Bao Y., Chen Y.-T.;
"Molecular cloning and nucleotide sequence of cDNA encoding human
muscle glycogen debranching enzyme.";
J. Biol. Chem. 267:9294-9299(1992).
[2]
NUCLEOTIDE SEQUENCE [MRNA], AND ALTERNATIVE SPLICING.
PubMed=8954797; DOI=10.1006/geno.1996.0611;
Bao Y., Dawson T.L. Jr., Chen Y.-T.;
"Human glycogen debranching enzyme gene (AGL): complete structural
organization and characterization of the 5' flanking region.";
Genomics 38:155-165(1996).
[3]
NUCLEOTIDE SEQUENCE [MRNA], AND ALTERNATIVE SPLICING.
TISSUE=Liver;
PubMed=9332391; DOI=10.1016/S0378-1119(97)00291-6;
Bao Y., Yang B.-Z., Dawson T.L. Jr., Chen Y.-T.;
"Isolation and nucleotide sequence of human liver glycogen debranching
enzyme mRNA: identification of multiple tissue-specific isoforms.";
Gene 197:389-398(1997).
[4]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1), AND VARIANTS.
PubMed=10982190; DOI=10.1007/s004390051017;
Okubo M., Horinishi A., Takeuchi M., Suzuki Y., Sakura N.,
Hasegawa Y., Igarashi T., Goto K., Tahara H., Uchimoto S., Omichi K.,
Kanno H., Hayasaka K., Murase T.;
"Heterogeneous mutations in the glycogen-debranching enzyme gene are
responsible for glycogen storage disease type IIIa in Japan.";
Hum. Genet. 106:108-115(2000).
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
TISSUE=Brain;
Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.,
Ohara O., Nagase T., Kikuno R.F.;
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
[6]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=16710414; DOI=10.1038/nature04727;
Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A.,
Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K.,
Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D.,
Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G.,
Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M.,
Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J.,
Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M.,
Loveland J., Lovell J., Lush M.J., Lyne R., Martin S.,
Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S.,
Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C.,
Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z.,
Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E.,
Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A.,
Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R.,
Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V.,
Beck S., Rogers J., Bentley D.R.;
"The DNA sequence and biological annotation of human chromosome 1.";
Nature 441:315-321(2006).
[7]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
Venter J.C.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
[8]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[9]
UBIQUITINATION, CHARACTERIZATION OF VARIANT GSD3 ARG-1448, INTERACTION
WITH NHLRC1, AND SUBCELLULAR LOCATION.
PubMed=17908927; DOI=10.1101/gad.1553207;
Cheng A., Zhang M., Gentry M.S., Worby C.A., Dixon J.E., Saltiel A.R.;
"A role for AGL ubiquitination in the glycogen storage disorders of
Lafora and Cori's disease.";
Genes Dev. 21:2399-2409(2007).
[10]
IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
PubMed=21269460; DOI=10.1186/1752-0509-5-17;
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.;
"Initial characterization of the human central proteome.";
BMC Syst. Biol. 5:17-17(2011).
[11]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-64, AND IDENTIFICATION
BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
TISSUE=Liver;
PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
Wang L., Ye M., Zou H.;
"An enzyme assisted RP-RPLC approach for in-depth analysis of human
liver phosphoproteome.";
J. Proteomics 96:253-262(2014).
[12]
VARIANT GSD3 ARG-1448, AND VARIANT ARG-1115.
PubMed=10571954;
DOI=10.1002/(SICI)1098-1004(199912)14:6<542::AID-HUMU15>3.0.CO;2-0;
Okubo M., Kanda F., Horinishi A., Takahashi K., Okuda S., Chihara K.,
Murase T.;
"Glycogen storage disease type IIIa: first report of a causative
missense mutation (G1448R) of the glycogen debranching enzyme gene
found in a homozygous patient.";
Hum. Mutat. 14:542-543(1999).
-!- FUNCTION: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-
alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-
glucosidase in glycogen degradation.
-!- CATALYTIC ACTIVITY: Transfers a segment of a (1->4)-alpha-D-glucan
to a new position in an acceptor, which may be glucose or a
(1->4)-alpha-D-glucan.
-!- CATALYTIC ACTIVITY: Hydrolysis of (1->6)-alpha-D-glucosidic branch
linkages in glycogen phosphorylase limit dextrin.
-!- SUBUNIT: Monomer. Interacts with NHLRC1/malin.
{ECO:0000269|PubMed:17908927}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:17908927}.
Note=Under glycogenolytic conditions localizes to the nucleus.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=3;
Name=1; Synonyms=2, 3, 4;
IsoId=P35573-1; Sequence=Displayed;
Note=The products of the mRNAs termed isoforms 1 to 4 are
identical.;
Name=5;
IsoId=P35573-2; Sequence=VSP_004270;
Name=6;
IsoId=P35573-3; Sequence=VSP_004271;
Note=Ref.2 (AAB48470) sequence is in conflict in position:
4:I->L. {ECO:0000305};
-!- TISSUE SPECIFICITY: Liver, kidney and lymphoblastoid cells express
predominantly isoform 1; whereas muscle and heart express not only
isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3
and 4). Isoforms 5 and 6 are present in both liver and muscle.
-!- PTM: The N-terminus is blocked.
-!- PTM: Ubiquitinated. {ECO:0000269|PubMed:17908927}.
-!- DISEASE: Glycogen storage disease 3 (GSD3) [MIM:232400]: A
metabolic disorder associated with an accumulation of abnormal
glycogen with short outer chains. It is clinically characterized
by hepatomegaly, hypoglycemia, short stature, and variable
myopathy. Glycogen storage disease type 3 includes different
forms: GSD type 3A patients lack glycogen debrancher enzyme
activity in both liver and muscle, while GSD type 3B patients are
enzyme-deficient in liver only. In rare cases, selective loss of
only 1 of the 2 debranching activities, glucosidase or
transferase, results in GSD type 3C or type 3D, respectively.
{ECO:0000269|PubMed:10571954, ECO:0000269|PubMed:17908927}.
Note=The disease is caused by mutations affecting the gene
represented in this entry.
-!- SIMILARITY: Belongs to the glycogen debranching enzyme family.
{ECO:0000305}.
-!- SEQUENCE CAUTION:
Sequence=BAD92104.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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EMBL; M85168; AAB41040.1; -; mRNA.
EMBL; U84007; AAB48466.1; -; mRNA.
EMBL; U84008; AAB48467.1; -; mRNA.
EMBL; U84009; AAB48468.1; -; mRNA.
EMBL; U84010; AAB48469.1; -; mRNA.
EMBL; U84011; AAB48470.1; -; mRNA.
EMBL; AB035443; BAA88405.1; -; Genomic_DNA.
EMBL; AB208867; BAD92104.1; ALT_INIT; mRNA.
EMBL; AC096949; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CH471097; EAW72985.1; -; Genomic_DNA.
EMBL; CH471097; EAW72982.1; -; Genomic_DNA.
EMBL; CH471097; EAW72983.1; -; Genomic_DNA.
EMBL; CH471097; EAW72987.1; -; Genomic_DNA.
EMBL; BC078663; AAH78663.1; -; mRNA.
CCDS; CCDS759.1; -. [P35573-1]
CCDS; CCDS760.1; -. [P35573-3]
RefSeq; NP_000019.2; NM_000028.2. [P35573-1]
RefSeq; NP_000633.2; NM_000642.2. [P35573-1]
RefSeq; NP_000634.2; NM_000643.2. [P35573-1]
RefSeq; NP_000635.2; NM_000644.2. [P35573-1]
RefSeq; NP_000637.2; NM_000646.2. [P35573-3]
RefSeq; XP_005270614.1; XM_005270557.2. [P35573-1]
UniGene; Hs.904; -.
ProteinModelPortal; P35573; -.
BioGrid; 106686; 52.
IntAct; P35573; 11.
MINT; MINT-2802883; -.
STRING; 9606.ENSP00000294724; -.
BindingDB; P35573; -.
ChEMBL; CHEMBL5272; -.
CAZy; GH13; Glycoside Hydrolase Family 13.
CAZy; GH133; Glycoside Hydrolase Family 133.
iPTMnet; P35573; -.
PhosphoSitePlus; P35573; -.
BioMuta; AGL; -.
DMDM; 116242491; -.
EPD; P35573; -.
MaxQB; P35573; -.
PaxDb; P35573; -.
PeptideAtlas; P35573; -.
PRIDE; P35573; -.
Ensembl; ENST00000294724; ENSP00000294724; ENSG00000162688. [P35573-1]
Ensembl; ENST00000361915; ENSP00000355106; ENSG00000162688. [P35573-1]
Ensembl; ENST00000370161; ENSP00000359180; ENSG00000162688. [P35573-3]
Ensembl; ENST00000370163; ENSP00000359182; ENSG00000162688. [P35573-1]
Ensembl; ENST00000370165; ENSP00000359184; ENSG00000162688. [P35573-1]
GeneID; 178; -.
KEGG; hsa:178; -.
UCSC; uc001dsi.2; human. [P35573-1]
CTD; 178; -.
DisGeNET; 178; -.
EuPathDB; HostDB:ENSG00000162688.15; -.
GeneCards; AGL; -.
GeneReviews; AGL; -.
HGNC; HGNC:321; AGL.
HPA; HPA028498; -.
HPA; HPA054340; -.
MalaCards; AGL; -.
MIM; 232400; phenotype.
MIM; 610860; gene.
neXtProt; NX_P35573; -.
OpenTargets; ENSG00000162688; -.
Orphanet; 366; Glycogen storage disease due to glycogen debranching enzyme deficiency.
PharmGKB; PA24618; -.
eggNOG; KOG3625; Eukaryota.
eggNOG; COG3408; LUCA.
GeneTree; ENSGT00390000012596; -.
HOVERGEN; HBG005824; -.
InParanoid; P35573; -.
KO; K01196; -.
OMA; MCIPGKI; -.
OrthoDB; EOG091G00L5; -.
PhylomeDB; P35573; -.
TreeFam; TF300697; -.
BioCyc; MetaCyc:HS08717-MONOMER; -.
BRENDA; 3.2.1.33; 2681.
Reactome; R-HSA-6798695; Neutrophil degranulation.
Reactome; R-HSA-70221; Glycogen breakdown (glycogenolysis).
GeneWiki; Glycogen_debranching_enzyme; -.
GenomeRNAi; 178; -.
PRO; PR:P35573; -.
Proteomes; UP000005640; Chromosome 1.
Bgee; ENSG00000162688; -.
CleanEx; HS_AGL; -.
ExpressionAtlas; P35573; baseline and differential.
Genevisible; P35573; HS.
GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO; GO:0005829; C:cytosol; TAS:Reactome.
GO; GO:0005576; C:extracellular region; TAS:Reactome.
GO; GO:1904813; C:ficolin-1-rich granule lumen; TAS:Reactome.
GO; GO:0016234; C:inclusion body; IEA:Ensembl.
GO; GO:0043033; C:isoamylase complex; TAS:ProtInc.
GO; GO:0005634; C:nucleus; IEA:Ensembl.
GO; GO:0016529; C:sarcoplasmic reticulum; IEA:Ensembl.
GO; GO:0034774; C:secretory granule lumen; TAS:Reactome.
GO; GO:0004134; F:4-alpha-glucanotransferase activity; EXP:Reactome.
GO; GO:0004135; F:amylo-alpha-1,6-glucosidase activity; EXP:Reactome.
GO; GO:0102500; F:beta-maltose 4-alpha-glucanotransferase activity; IEA:UniProtKB-EC.
GO; GO:0004133; F:glycogen debranching enzyme activity; TAS:ProtInc.
GO; GO:0030247; F:polysaccharide binding; IEA:Ensembl.
GO; GO:0031593; F:polyubiquitin modification-dependent protein binding; IEA:Ensembl.
GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.
GO; GO:0005980; P:glycogen catabolic process; IBA:GO_Central.
GO; GO:0043312; P:neutrophil degranulation; TAS:Reactome.
GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
CDD; cd11327; AmyAc_Glg_debranch_2; 1.
InterPro; IPR008928; 6-hairpin_glycosidase-like.
InterPro; IPR010401; AGL/Gdb1.
InterPro; IPR032788; AGL_central.
InterPro; IPR029436; AGL_euk_N.
InterPro; IPR032792; AGL_glucanoTrfase.
InterPro; IPR032790; GDE_C.
InterPro; IPR006421; Glycogen_debranch_met.
InterPro; IPR017853; Glycoside_hydrolase_SF.
PANTHER; PTHR10569; PTHR10569; 1.
Pfam; PF06202; GDE_C; 1.
Pfam; PF14701; hDGE_amylase; 1.
Pfam; PF14702; hGDE_central; 1.
Pfam; PF14699; hGDE_N; 1.
SUPFAM; SSF48208; SSF48208; 2.
SUPFAM; SSF51445; SSF51445; 2.
TIGRFAMs; TIGR01531; glyc_debranch; 1.
1: Evidence at protein level;
Alternative splicing; Complete proteome; Cytoplasm;
Direct protein sequencing; Disease mutation; Glycogen biosynthesis;
Glycogen storage disease; Glycosidase; Glycosyltransferase; Hydrolase;
Multifunctional enzyme; Phosphoprotein; Polymorphism;
Reference proteome; Transferase; Ubl conjugation.
CHAIN 1 1532 Glycogen debranching enzyme.
/FTId=PRO_0000087450.
REGION 1 ? 4-alpha-glucanotransferase.
REGION ? 1532 Amylo-1,6-glucosidase.
ACT_SITE 526 526 {ECO:0000250}.
ACT_SITE 529 529 {ECO:0000250}.
ACT_SITE 627 627 {ECO:0000250}.
MOD_RES 64 64 Phosphoserine.
{ECO:0000244|PubMed:24275569}.
VAR_SEQ 1 27 MGHSKQIRILLLNEMEKLEKTLFRLEQ -> MSLLTCAFYL
(in isoform 5). {ECO:0000305}.
/FTId=VSP_004270.
VAR_SEQ 1 27 MGHSKQIRILLLNEMEKLEKTLFRLEQ -> MAPILSINLF
I (in isoform 6). {ECO:0000305}.
/FTId=VSP_004271.
VARIANT 38 38 T -> A (in dbSNP:rs35278779).
/FTId=VAR_032084.
VARIANT 229 229 Q -> R (in dbSNP:rs17121403).
/FTId=VAR_028051.
VARIANT 387 387 R -> Q (in dbSNP:rs17121464).
/FTId=VAR_009621.
VARIANT 701 701 A -> S (in dbSNP:rs3736297).
/FTId=VAR_028052.
VARIANT 962 962 S -> C (in dbSNP:rs34714252).
/FTId=VAR_032085.
VARIANT 1067 1067 P -> S (in dbSNP:rs3753494).
/FTId=VAR_020389.
VARIANT 1115 1115 G -> R (in dbSNP:rs2230307).
{ECO:0000269|PubMed:10571954}.
/FTId=VAR_009230.
VARIANT 1144 1144 I -> N (in dbSNP:rs2230308).
/FTId=VAR_028053.
VARIANT 1207 1207 A -> T (in dbSNP:rs11807956).
/FTId=VAR_051010.
VARIANT 1253 1253 R -> H (in dbSNP:rs12043139).
/FTId=VAR_028054.
VARIANT 1343 1343 E -> K (in dbSNP:rs112795811).
/FTId=VAR_009622.
VARIANT 1448 1448 G -> R (in GSD3; deficient in ability to
bind glycogen; unstable due to enhanced
ubiquitination; forms aggresomes upon
proteasome impairment;
dbSNP:rs118203964).
{ECO:0000269|PubMed:10571954,
ECO:0000269|PubMed:17908927}.
/FTId=VAR_009231.
VARIANT 1487 1487 R -> G (in dbSNP:rs12118058).
/FTId=VAR_028055.
CONFLICT 1398 1398 W -> G (in Ref. 1; AAB41040, 2; AAB48466/
AAB48467/AAB48468/AAB48469/AAB48470 and
3). {ECO:0000305}.
SEQUENCE 1532 AA; 174764 MW; 9BF1BCC43B7904D3 CRC64;
MGHSKQIRIL LLNEMEKLEK TLFRLEQGYE LQFRLGPTLQ GKAVTVYTNY PFPGETFNRE
KFRSLDWENP TEREDDSDKY CKLNLQQSGS FQYYFLQGNE KSGGGYIVVD PILRVGADNH
VLPLDCVTLQ TFLAKCLGPF DEWESRLRVA KESGYNMIHF TPLQTLGLSR SCYSLANQLE
LNPDFSRPNR KYTWNDVGQL VEKLKKEWNV ICITDVVYNH TAANSKWIQE HPECAYNLVN
SPHLKPAWVL DRALWRFSCD VAEGKYKEKG IPALIENDHH MNSIRKIIWE DIFPKLKLWE
FFQVDVNKAV EQFRRLLTQE NRRVTKSDPN QHLTIIQDPE YRRFGCTVDM NIALTTFIPH
DKGPAAIEEC CNWFHKRMEE LNSEKHRLIN YHQEQAVNCL LGNVFYERLA GHGPKLGPVT
RKHPLVTRYF TFPFEEIDFS MEESMIHLPN KACFLMAHNG WVMGDDPLRN FAEPGSEVYL
RRELICWGDS VKLRYGNKPE DCPYLWAHMK KYTEITATYF QGVRLDNCHS TPLHVAEYML
DAARNLQPNL YVVAELFTGS EDLDNVFVTR LGISSLIREA MSAYNSHEEG RLVYRYGGEP
VGSFVQPCLR PLMPAIAHAL FMDITHDNEC PIVHRSAYDA LPSTTIVSMA CCASGSTRGY
DELVPHQISV VSEERFYTKW NPEALPSNTG EVNFQSGIIA ARCAISKLHQ ELGAKGFIQV
YVDQVDEDIV AVTRHSPSIH QSVVAVSRTA FRNPKTSFYS KEVPQMCIPG KIEEVVLEAR
TIERNTKPYR KDENSINGTP DITVEIREHI QLNESKIVKQ AGVATKGPNE YIQEIEFENL
SPGSVIIFRV SLDPHAQVAV GILRNHLTQF SPHFKSGSLA VDNADPILKI PFASLASRLT
LAELNQILYR CESEEKEDGG GCYDIPNWSA LKYAGLQGLM SVLAEIRPKN DLGHPFCNNL
RSGDWMIDYV SNRLISRSGT IAEVGKWLQA MFFYLKQIPR YLIPCYFDAI LIGAYTTLLD
TAWKQMSSFV QNGSTFVKHL SLGSVQLCGV GKFPSLPILS PALMDVPYRL NEITKEKEQC
CVSLAAGLPH FSSGIFRCWG RDTFIALRGI LLITGRYVEA RNIILAFAGT LRHGLIPNLL
GEGIYARYNC RDAVWWWLQC IQDYCKMVPN GLDILKCPVS RMYPTDDSAP LPAGTLDQPL
FEVIQEAMQK HMQGIQFRER NAGPQIDRNM KDEGFNITAG VDEETGFVYG GNRFNCGTWM
DKMGESDRAR NRGIPATPRD GSAVEIVGLS KSAVRWLLEL SKKNIFPYHE VTVKRHGKAI
KVSYDEWNRK IQDNFEKLFH VSEDPSDLNE KHPNLVHKRG IYKDSYGASS PWCDYQLRPN
FTIAMVVAPE LFTTEKAWKA LEIAEKKLLG PLGMKTLDPD DMVYCGIYDN ALDNDNYNLA
KGFNYHQGPE WLWPIGYFLR AKLYFSRLMG PETTAKTIVL VKNVLSRHYV HLERSPWKGL
PELTNENAQY CPFSCETQAW SIATILETLY DL


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AGMX2 AGL Gene amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
CSB-EL001446DO Dog amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (AGL) ELISA kit, Species Dog, Sample Type serum, plasma 96T
CSB-EL001446RB Rabbit amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (AGL) ELISA kit, Species Rabbit, Sample Type serum, plasma 96T
CSB-EL001446HU Human amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (AGL) ELISA kit, Species Human, Sample Type serum, plasma 96T
CSB-EL001446HO Horse amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (AGL) ELISA kit, Species Horse, Sample Type serum, plasma 96T
18-272-195667 alpha Glucosidase II - Rabbit polyclonal to alpha Glucosidase II; EC 3.2.1.84; Glucosidase II subunit alpha Polyclonal 0.05 ml
EIAAB25109 Gcs1,Glucosidase 1,Glycoprotein-processing glucosidase I,Mannosyl-oligosaccharide glucosidase,Mogs,Mouse,Mus musculus
22786 Human alpha-Glucosidase(alpha-Glu,α-Glu) ELISA Kit 96T
DAGD-100 QuantiChrom™ α-Glucosidase Assay Kit, Quantitative determination of α-glucosidase activity by colorimetric (405nm) method 100Tests
DBGD-100 QuantiChrom™ β-Glucosidase Assay Kit, Quantitative determination of β-glucosidase activity by colorimetric (405nm) method 100Tests
EIAAB25108 GCS1,Homo sapiens,Human,Mannosyl-oligosaccharide glucosidase,MOGS,Processing A-glucosidase I
EIAAB25110 Gcs1,Glycoprotein-processing glucosidase I,Mannosyl-oligosaccharide glucosidase,Mogs,Rat,Rattus norvegicus
GTX102237 alpha Glucosidase II 100 µg
GTX12238 Glucosidase II alpha 50 µl
GTX102205 alpha Glucosidase II 100 µl
'H00002548-P01-10 Alpha-glucosidase antigen 10
orb40917 alpha Glucosidase II antibody 100 ug
'H00002548-Q01-25 Alpha-glucosidase antigen 25
'H00002548-Q01-10 Alpha-glucosidase antigen 10
'H00023193-Q01-25 Alpha-glucosidase 2 _ GANantigen 25
'H00023193-Q01-10 Alpha-glucosidase 2 _ GANantigen 10
'H00023193-P01-25 Alpha-glucosidase 2 _ GANantigen 25
'H00023193-P01-10 Alpha-glucosidase 2 _ GANantigen 10
KA1608 alpha-Glucosidase Assay Kit 1 Kit
Z5030049 Alpha-Glucosidase Assay Kit 100 assays


 

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