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Glycoprotein UL22A

 UL22A_HCMVA             Reviewed;         103 AA.
P16845; Q910H5; Q910K8; Q910L5; Q910N2; Q910S8; Q910U1; Q918F6;
Q918F7; Q918F8; Q918F9; Q918G0; Q918G1;
01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
15-FEB-2005, sequence version 2.
12-SEP-2018, entry version 54.
RecName: Full=Glycoprotein UL22A;
Flags: Precursor;
Name=UL22A; Synonyms=UL20A;
Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5).
Viruses; dsDNA viruses, no RNA stage; Herpesvirales; Herpesviridae;
Betaherpesvirinae; Cytomegalovirus.
NCBI_TaxID=10360;
NCBI_TaxID=9606; Homo sapiens (Human).
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=2161319;
Chee M.S., Bankier A.T., Beck S., Bohni R., Brown C.M., Cerny R.,
Horsnell T., Hutchison C.A. III, Kouzarides T., Martignetti J.A.,
Preddie E., Satchwell S.C., Tomlinson P., Weston K.M., Barrell B.G.;
"Analysis of the protein-coding content of the sequence of human
cytomegalovirus strain AD169.";
Curr. Top. Microbiol. Immunol. 154:125-169(1990).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Isolate clinical 17A, Isolate clinical 19A,
Isolate clinical 21A, Isolate clinical 22A, Isolate clinical 27A,
Isolate clinical 29A, Isolate clinical 30A, Isolate clinical 33B,
Isolate clinical 38A, Isolate clinical 3A, Isolate clinical 44A,
Isolate clinical 47A, Isolate clinical 48A, Isolate clinical 49A,
Isolate clinical 56A, Isolate clinical 5A, Isolate clinical 79A,
Isolate clinical 8A, Isolate clinical 95A, and Isolate clinical 9A;
PubMed=11928987; DOI=10.1023/A:1014033920070;
Scott G.M., Barrell B.G., Oram J., Rawlinson W.D.;
"Characterisation of transcripts from the human cytomegalovirus genes
TRL7, UL20a, UL36, UL65, UL94, US3 and US34.";
Virus Genes 24:39-48(2002).
[3]
GENOME REANNOTATION.
PubMed=12533697; DOI=10.1099/vir.0.18606-0;
Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J.,
Alcendor D.J., McGeoch D.J., Hayward G.S.;
"The human cytomegalovirus genome revisited: comparison with the
chimpanzee cytomegalovirus genome.";
J. Gen. Virol. 84:17-28(2003).
[4]
ERRATUM.
Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J.,
Alcendor D.J., McGeoch D.J., Hayward G.S.;
J. Gen. Virol. 84:1053-1053(2003).
[5]
IDENTIFICATION.
PubMed=15452216; DOI=10.1128/JVI.78.20.10960-10966.2004;
Varnum S.M., Streblow D.N., Monroe M.E., Smith P., Auberry K.J.,
Pasa-Tolic L., Wang D., Camp D.G. II, Rodland K., Wiley S., Britt W.,
Shenk T., Smith R.D., Nelson J.A.;
"Identification of proteins in human cytomegalovirus (HCMV) particles:
the HCMV proteome.";
J. Virol. 78:10960-10966(2004).
[6]
ERRATUM.
Varnum S.M., Streblow D.N., Monroe M.E., Smith P., Auberry K.J.,
Pasa-Tolic L., Wang D., Camp D.G. II, Rodland K., Wiley S., Britt W.,
Shenk T., Smith R.D., Nelson J.A.;
J. Virol. 78:13395-13395(2004).
-!- SUBCELLULAR LOCATION: Virion.
-!- SIMILARITY: Belongs to the HHV-5 UL22A protein family.
{ECO:0000305}.
-!- SEQUENCE CAUTION:
Sequence=CAA35421.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
-----------------------------------------------------------------------
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Distributed under the Creative Commons Attribution (CC BY 4.0) License
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EMBL; X17403; CAA35421.1; ALT_SEQ; Genomic_DNA.
EMBL; AF413626; AAL08513.1; -; Genomic_DNA.
EMBL; AF413627; AAL08514.1; -; Genomic_DNA.
EMBL; AF413628; AAL08515.1; -; Genomic_DNA.
EMBL; AF413629; AAL08516.1; -; Genomic_DNA.
EMBL; AF413630; AAL08517.1; -; Genomic_DNA.
EMBL; AF413631; AAL08518.1; -; Genomic_DNA.
EMBL; AF413632; AAL08519.1; -; Genomic_DNA.
EMBL; AF413633; AAL08520.1; -; Genomic_DNA.
EMBL; AF413634; AAL08521.1; -; Genomic_DNA.
EMBL; AF413635; AAL08522.1; -; Genomic_DNA.
EMBL; AF413636; AAL08523.1; -; Genomic_DNA.
EMBL; AF413637; AAL08524.1; -; Genomic_DNA.
EMBL; AF413638; AAL08525.1; -; Genomic_DNA.
EMBL; AF413639; AAL08526.1; -; Genomic_DNA.
EMBL; AF413640; AAL08527.1; -; Genomic_DNA.
EMBL; AF413641; AAL08528.1; -; Genomic_DNA.
EMBL; AF413642; AAL08529.1; -; Genomic_DNA.
EMBL; AF413643; AAL08530.1; -; Genomic_DNA.
EMBL; AF413644; AAL08531.1; -; Genomic_DNA.
EMBL; AF413645; AAL08532.1; -; Genomic_DNA.
EMBL; BK000394; DAA00126.1; -; Genomic_DNA.
PIR; S09785; S09785.
RefSeq; YP_081481.1; NC_006273.2.
PRIDE; P16845; -.
GeneID; 3077571; -.
KEGG; vg:3077571; -.
KO; K22784; -.
OrthoDB; VOG090001U6; -.
Proteomes; UP000008991; Genome.
Proteomes; UP000008992; Genome.
GO; GO:0019012; C:virion; IEA:UniProtKB-SubCell.
InterPro; IPR009245; Cytomegalo_UL22A.
Pfam; PF05984; Cytomega_UL20A; 1.
ProDom; PD080095; Cytomega_UL20A; 1.
3: Inferred from homology;
Complete proteome; Glycoprotein; Reference proteome; Signal; Virion.
SIGNAL 1 20 {ECO:0000255}.
CHAIN 21 103 Glycoprotein UL22A.
/FTId=PRO_0000037454.
CARBOHYD 49 49 N-linked (GlcNAc...) asparagine; by host.
{ECO:0000255}.
VARIANT 5 5 L -> V (in strain: Isolate clinical 48A).
VARIANT 10 10 Missing (in strain: Isolate clinical 17A,
Isolate clinical 27A, Isolate clinical
30A, Isolate clinical 33B, Isolate
clinical 47A, Isolate clinical 48A and
Isolate clinical 79A).
VARIANT 33 33 E -> K (in strain: Isolate clinical 5A,
Isolate clinical 44A and Isolate clinical
49A).
VARIANT 39 42 ADGS -> TNSDG (in strain: Isolate
clinical 3A, Isolate clinical 5A, Isolate
clinical 17A, Isolate clinical 19A,
Isolate clinical 21A, Isolate clinical
22A, Isolate clinical 27A, Isolate
clinical 29A, Isolate clinical 30A,
Isolate clinical 33B, Isolate clinical
38A, Isolate clinical 44A, Isolate
clinical 47A, Isolate clinical 48A,
Isolate clinical 49A, Isolate clinical
56A and Isolate clinical 79A).
VARIANT 43 43 N -> NN (in strain: Isolate clinical 29A
and Isolate clinical 38A).
VARIANT 46 49 PSKN -> RNKD (in strain: Isolate clinical
29A, Isolate clinical 38A and Isolate
clinical 56A).
VARIANT 62 62 D -> N (in strain: Isolate clinical 5A,
Isolate clinical 17A, Isolate clinical
30A, Isolate clinical 33B, Isolate
clinical 44A, Isolate clinical 47A,
Isolate clinical 48A, Isolate clinical
49A and Isolate clinical 79A).
VARIANT 68 68 E -> EE (in strain: Isolate clinical 5A,
Isolate clinical 30A, Isolate clinical
33B, Isolate clinical 44A, Isolate
clinical 47A, Isolate clinical 48A,
Isolate clinical 49A and Isolate clinical
79A).
VARIANT 68 68 E -> GD (in strain: Isolate clinical 21A,
Isolate clinical 22A, Isolate clinical
29A, Isolate clinical 38A and Isolate
clinical 56A).
VARIANT 76 76 G -> T (in strain: Isolate clinical 21A,
Isolate clinical 22A, Isolate clinical
29A, Isolate clinical 38A and Isolate
clinical 56A).
VARIANT 79 79 S -> G (in strain: Isolate clinical 5A,
Isolate clinical 21A, Isolate clinical
22A, Isolate clinical 29A, Isolate
clinical 38A, Isolate clinical 44A,
Isolate clinical 49A and Isolate clinical
56A).
VARIANT 80 80 E -> N (in strain: Isolate clinical 21A,
Isolate clinical 22A, Isolate clinical
29A, Isolate clinical 38A and Isolate
clinical 56A).
VARIANT 85 85 Q -> QE (in strain: Isolate clinical 5A,
Isolate clinical 17A, Isolate clinical
21A, Isolate clinical 22A, Isolate
clinical 29A, Isolate clinical 30A,
Isolate clinical 33B, Isolate clinical
38A, Isolate clinical 44A, Isolate
clinical 47A, Isolate clinical 48A,
clinical Isolate 49A, Isolate clinical
56A and Isolate clinical 79A).
VARIANT 88 88 D -> N (in strain: Isolate clinical 29A
and Isolate clinical 38A).
VARIANT 92 92 E -> G (in strain: Isolate clinical 17A,
Isolate clinical 21A and Isolate clinical
22A, Isolate clinical 30A, Isolate
clinical 33B, Isolate clinical 47A,
Isolate clinical 48A and Isolate clinical
79A).
VARIANT 92 92 E -> K (in strain: Isolate clinical 56A).
VARIANT 93 95 NQA -> EHT (in strain: Isolate clinical
5A, Isolate clinical 17A, Isolate
clinical 21A, Isolate clinical 22A,
Isolate clinical 29A, Isolate clinical
30A, Isolate clinical 33B, Isolate
clinical 38A, Isolate clinical 44A,
Isolate clinical 47A, Isolate clinical
48A, Isolate clinical 49A, Isolate
clinical 56A and Isolate clinical 79A).
VARIANT 93 93 N -> D (in strain: Isolate clinical 8A).
VARIANT 98 100 NEK -> DDE (in strain: Isolate clinical
27A).
VARIANT 99 99 Missing (in strain: Isolate clinical
49A).
VARIANT 101 102 KI -> T (in strain: Isolate clinical 5A,
Isolate clinical 17A, Isolate clinical
21A, Isolate clinical 22A, Isolate
clinical 29A, Isolate clinical 30A,
Isolate clinical 33B, Isolate clinical
38A, Isolate clinical 44A, Isolate
clinical 47A, Isolate clinical 48A,
Isolate clinical 49A, Isolate clinical
56A and Isolate clinical 79A).
SEQUENCE 103 AA; 11147 MW; 86941819BD83ECCD CRC64;
MARRLWILSL LAVTLTVALA APSQKSKRSV TVEQPSTSAD GSNTTPSKNV TLSQGGSTTD
GDEDYSGEYD VLITDGDGSE HQQPQKTDEH KENQAKENEK KIQ


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