Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

HLA class II histocompatibility antigen, DM beta chain (MHC class II antigen DMB) (Really interesting new gene 7 protein)

 DMB_HUMAN               Reviewed;         263 AA.
P28068; O77936; Q13012; Q29751; Q58ZE2; Q5SNZ8; Q5STC4; Q9XRX2;
01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
01-AUG-1992, sequence version 1.
23-MAY-2018, entry version 176.
RecName: Full=HLA class II histocompatibility antigen, DM beta chain;
AltName: Full=MHC class II antigen DMB;
AltName: Full=Really interesting new gene 7 protein;
Flags: Precursor;
Name=HLA-DMB; Synonyms=DMB, RING7;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA] (ALLELE DMB*01:01).
PubMed=1922365; DOI=10.1038/353571a0;
Kelly A.P., Monaco J.J., Cho S., Trowsdale J.;
"A new human HLA class II-related locus, DM.";
Nature 353:571-573(1991).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE DMB*01:01).
PubMed=8034636;
Radley E., Alderton R.P., Kelly A., Trowsdale J., Beck S.;
"Genomic organization of HLA-DMA and HLA-DMB. Comparison of the gene
organization of all six class II families in the human major
histocompatibility complex.";
J. Biol. Chem. 269:18834-18838(1994).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ALLELE DMB*01:01).
PubMed=8568858; DOI=10.1006/jmbi.1996.0001;
Beck S., Abdulla S., Alderton R.P., Glynne R.J., Gut I.G.,
Hosking L.K., Jackson A., Kelly A., Newell W.R., Sanseau P.,
Radley E., Thorpe K.L., Trowsdale J.;
"Evolutionary dynamics of non-coding sequences within the class II
region of the human MHC.";
J. Mol. Biol. 255:1-13(1996).
[4]
NUCLEOTIDE SEQUENCE [MRNA] (ALLELE DMB*01:07).
PubMed=15787724; DOI=10.1111/j.1399-0039.2005.00385.x;
Gu H., Moon S.-M., Kim J.-J., Ryu H.-J., Kwack K., Kimm K., Lee J.-K.,
Oh B.;
"Identification of a novel HLA-DMB allele (DMB*0107) in the Korean
population.";
Tissue Antigens 65:393-394(2005).
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND VARIANT THR-197.
PubMed=14574404; DOI=10.1038/nature02055;
Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
"The DNA sequence and analysis of human chromosome 6.";
Nature 425:805-811(2003).
[6]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
Venter J.C.;
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
[7]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ALLELE DMB*01:01).
TISSUE=Lymph;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[8]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 114-207 (ALLELES DMB*01:02 AND
DMB*01:03).
PubMed=8225438; DOI=10.1007/BF00171797;
Sanderson F., Powis S.H., Kelly A.P., Trowsdale J.;
"Limited polymorphism in HLA-DM does not involve the peptide binding
groove.";
Immunogenetics 39:56-58(1994).
[9]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 121-200 (ALLELE DMB*01:04).
PubMed=8406617; DOI=10.1007/BF00184526;
Carrington M., Yeager M., Mann D.;
"Characterization of HLA-DMB polymorphism.";
Immunogenetics 38:446-449(1993).
[10]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 113-207 (ALLELE DMB*01:05).
TISSUE=Blood;
PubMed=9157091; DOI=10.1016/0198-8859(95)00171-9;
Kim T.-G., Carrington M., Choi H.B., Kim H.Y., Han H.;
"Three HLA-DMB variants in Korean patients with autoimmune diseases.";
Hum. Immunol. 46:58-60(1996).
[11]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 19-112 AND 152-207 (ALLELE
DMB*01:06).
PubMed=10885572; DOI=10.1034/j.1399-0039.2000.550514.x;
McTernan C.L., Mijovic C.H., Cockram C.S., Barnett A.H.;
"The nucleotide sequence of a new DMB allele, DMB*0106.";
Tissue Antigens 55:470-472(2000).
[12]
FUNCTION.
PubMed=8849454; DOI=10.1126/science.274.5287.618;
Weber D.A., Evavold B.D., Jensen P.E.;
"Enhanced dissociation of HLA-DR-bound peptides in the presence of
HLA-DM.";
Science 274:618-620(1996).
[13]
SUBCELLULAR LOCATION, AND MUTAGENESIS OF TYR-248 AND LEU-251.
PubMed=8757605;
Copier J., Kleijmeer M.J., Ponnambalam S., Oorschot V., Potter P.,
Trowsdale J., Kelly A.;
"Targeting signal and subcellular compartments involved in the
intracellular trafficking of HLA-DMB.";
J. Immunol. 157:1017-1027(1996).
[14]
GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-110.
TISSUE=Plasma;
PubMed=16335952; DOI=10.1021/pr0502065;
Liu T., Qian W.-J., Gritsenko M.A., Camp D.G. II, Monroe M.E.,
Moore R.J., Smith R.D.;
"Human plasma N-glycoproteome analysis by immunoaffinity subtraction,
hydrazide chemistry, and mass spectrometry.";
J. Proteome Res. 4:2070-2080(2005).
[15]
X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 19-218 IN COMPLEX WITH DMA,
FUNCTION, SUBUNIT, AND DISULFIDE BONDS.
PubMed=9768757; DOI=10.1016/S1074-7613(00)80620-2;
Mosyak L., Zaller D.M., Wiley D.C.;
"The structure of HLA-DM, the peptide exchange catalyst that loads
antigen onto class II MHC molecules during antigen presentation.";
Immunity 9:377-383(1998).
[16]
X-RAY CRYSTALLOGRAPHY (2.27 ANGSTROMS) OF 19-218 IN COMPLEX WITH DMA,
FUNCTION, SUBUNIT, AND DISULFIDE BONDS.
PubMed=16547258; DOI=10.4049/jimmunol.176.7.4208;
Nicholson M.J., Moradi B., Seth N.P., Xing X., Cuny G.D., Stein R.L.,
Wucherpfennig K.W.;
"Small molecules that enhance the catalytic efficiency of HLA-DM.";
J. Immunol. 176:4208-4220(2006).
-!- FUNCTION: Plays a critical role in catalyzing the release of class
II-associated invariant chain peptide (CLIP) from newly
synthesized MHC class II molecules and freeing the peptide binding
site for acquisition of antigenic peptides. In B-cells, the
interaction between HLA-DM and MHC class II molecules is regulated
by HLA-DO. {ECO:0000269|PubMed:16547258,
ECO:0000269|PubMed:8849454, ECO:0000269|PubMed:9768757}.
-!- SUBUNIT: Heterodimer of an alpha chain (DMA) and a beta chain
(DMB). {ECO:0000269|PubMed:16547258, ECO:0000269|PubMed:9768757}.
-!- INTERACTION:
Q6ICR9:HLA-DMA; NbExp=5; IntAct=EBI-2877138, EBI-16027071;
-!- SUBCELLULAR LOCATION: Late endosome membrane
{ECO:0000269|PubMed:8757605}; Single-pass type I membrane protein
{ECO:0000269|PubMed:8757605}. Lysosome membrane
{ECO:0000269|PubMed:8757605}; Single-pass type I membrane protein
{ECO:0000269|PubMed:8757605}. Note=Localizes to late endocytic
compartment. Associates with lysosome membranes.
-!- DOMAIN: The YXXZ (Tyr-Xaa-Xaa-Zaa, where Zaa is a hydrophobic
residue) motif mediates the targeting to the lysosomal
compartments.
-!- POLYMORPHISM: The following alleles of DMB are known: DMB*01:01,
DMB*01:02, DMB*01:03, DMB*01:04 (DMB3.4), DMB*01:05, DMB*01:06,
and DMB*01:07. The sequence shown is that of DMB*01:01.
-!- SIMILARITY: Belongs to the MHC class II family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; Z23139; CAA80670.1; -; mRNA.
EMBL; U15085; AAB60387.1; -; mRNA.
EMBL; X76776; CAA54171.1; -; Genomic_DNA.
EMBL; X87344; CAA60782.1; -; Genomic_DNA.
EMBL; AY645722; AAV97947.1; -; mRNA.
EMBL; AL662845; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AL645941; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AL935042; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; BX088556; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; BX927138; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CR936913; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CR759798; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CR752645; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CH471081; EAX03657.1; -; Genomic_DNA.
EMBL; BC027175; AAH27175.1; -; mRNA.
EMBL; Z24750; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; Z24751; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; U00700; AAA03296.1; -; Genomic_DNA.
EMBL; U16762; AAC50514.1; -; Genomic_DNA.
EMBL; AF134890; AAD30279.1; -; Genomic_DNA.
EMBL; AF072680; AAC26112.1; -; Genomic_DNA.
CCDS; CCDS4760.1; -.
PIR; I37533; I37533.
RefSeq; NP_002109.2; NM_002118.4.
UniGene; Hs.351279; -.
PDB; 1HDM; X-ray; 2.50 A; B=19-218.
PDB; 2BC4; X-ray; 2.27 A; B/D=19-218.
PDB; 4FQX; X-ray; 2.60 A; D=19-211.
PDB; 4GBX; X-ray; 3.00 A; D=19-211.
PDB; 4I0P; X-ray; 3.20 A; B/F=21-211.
PDBsum; 1HDM; -.
PDBsum; 2BC4; -.
PDBsum; 4FQX; -.
PDBsum; 4GBX; -.
PDBsum; 4I0P; -.
ProteinModelPortal; P28068; -.
SMR; P28068; -.
BioGrid; 109354; 11.
DIP; DIP-6185N; -.
IntAct; P28068; 10.
MINT; P28068; -.
STRING; 9606.ENSP00000398890; -.
iPTMnet; P28068; -.
PhosphoSitePlus; P28068; -.
BioMuta; HLA-DMB; -.
DMDM; 133160; -.
PaxDb; P28068; -.
PeptideAtlas; P28068; -.
PRIDE; P28068; -.
DNASU; 3109; -.
Ensembl; ENST00000383231; ENSP00000372718; ENSG00000241674.
Ensembl; ENST00000395312; ENSP00000378723; ENSG00000242092.
Ensembl; ENST00000412948; ENSP00000413471; ENSG00000241296.
Ensembl; ENST00000418107; ENSP00000398890; ENSG00000242574.
Ensembl; ENST00000424822; ENSP00000414817; ENSG00000234154.
Ensembl; ENST00000428420; ENSP00000393646; ENSG00000239329.
Ensembl; ENST00000440078; ENSP00000411321; ENSG00000226264.
Ensembl; ENST00000450897; ENSP00000408453; ENSG00000242386.
GeneID; 3109; -.
KEGG; hsa:3109; -.
UCSC; uc003ocl.2; human.
CTD; 3109; -.
DisGeNET; 3109; -.
EuPathDB; HostDB:ENSG00000242574.8; -.
GeneCards; HLA-DMB; -.
H-InvDB; HIX0166396; -.
H-InvDB; HIX0207613; -.
H-InvDB; HIX0207705; -.
H-InvDB; HIX0207762; -.
HGNC; HGNC:4935; HLA-DMB.
HPA; HPA012298; -.
MIM; 142856; gene.
neXtProt; NX_P28068; -.
PharmGKB; PA35059; -.
eggNOG; ENOG410IFNH; Eukaryota.
eggNOG; ENOG410YU9X; LUCA.
HOVERGEN; HBG007327; -.
InParanoid; P28068; -.
KO; K06752; -.
OrthoDB; EOG091G0G84; -.
PhylomeDB; P28068; -.
TreeFam; TF335727; -.
Reactome; R-HSA-2132295; MHC class II antigen presentation.
SIGNOR; P28068; -.
ChiTaRS; HLA-DMB; human.
EvolutionaryTrace; P28068; -.
GeneWiki; HLA-DMB; -.
GenomeRNAi; 3109; -.
PRO; PR:P28068; -.
Proteomes; UP000005640; Chromosome 6.
Bgee; ENSG00000242574; -.
CleanEx; HS_HLA-DMB; -.
ExpressionAtlas; P28068; baseline and differential.
Genevisible; P28068; HS.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO; GO:0005765; C:lysosomal membrane; TAS:Reactome.
GO; GO:0042613; C:MHC class II protein complex; IDA:UniProtKB.
GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProtKB.
GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IMP:UniProtKB.
GO; GO:0006955; P:immune response; IEA:InterPro.
GO; GO:0002399; P:MHC class II protein complex assembly; IMP:UniProtKB.
GO; GO:0002503; P:peptide antigen assembly with MHC class II protein complex; IDA:UniProtKB.
GO; GO:2001190; P:positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; IMP:UniProtKB.
GO; GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.
Gene3D; 2.60.40.10; -; 1.
Gene3D; 3.10.320.10; -; 1.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003006; Ig/MHC_CS.
InterPro; IPR003597; Ig_C1-set.
InterPro; IPR011162; MHC_I/II-like_Ag-recog.
InterPro; IPR014745; MHC_II_a/b_N.
InterPro; IPR000353; MHC_II_b_N.
Pfam; PF07654; C1-set; 1.
Pfam; PF00969; MHC_II_beta; 1.
SMART; SM00407; IGc1; 1.
SMART; SM00921; MHC_II_beta; 1.
SUPFAM; SSF48726; SSF48726; 1.
SUPFAM; SSF54452; SSF54452; 1.
PROSITE; PS50835; IG_LIKE; 1.
PROSITE; PS00290; IG_MHC; 1.
1: Evidence at protein level;
3D-structure; Complete proteome; Disulfide bond; Endosome;
Glycoprotein; Immunity; Immunoglobulin domain; Lysosome; Membrane;
MHC II; Polymorphism; Reference proteome; Signal; Transmembrane;
Transmembrane helix.
SIGNAL 1 18 {ECO:0000255}.
CHAIN 19 263 HLA class II histocompatibility antigen,
DM beta chain.
/FTId=PRO_0000018960.
TOPO_DOM 19 218 Lumenal. {ECO:0000255}.
TRANSMEM 219 239 Helical. {ECO:0000255}.
TOPO_DOM 240 263 Cytoplasmic. {ECO:0000255}.
DOMAIN 114 208 Ig-like C1-type.
REGION 19 112 Beta-1.
REGION 113 207 Beta-2.
REGION 208 218 Connecting peptide. {ECO:0000255}.
MOTIF 248 251 YXXZ motif.
CARBOHYD 110 110 N-linked (GlcNAc...) asparagine.
{ECO:0000269|PubMed:16335952}.
DISULFID 29 97
DISULFID 135 192
VARIANT 28 28 T -> A (in allele DMB*01:07;
dbSNP:rs17583782).
/FTId=VAR_050360.
VARIANT 45 45 S -> F (in allele DMB*01:06;
dbSNP:rs41560814).
/FTId=VAR_016752.
VARIANT 49 49 D -> V (in allele DMB*01:07;
dbSNP:rs17617333).
/FTId=VAR_050361.
VARIANT 71 71 S -> N (in allele DMB*01:07;
dbSNP:rs17617321).
/FTId=VAR_050362.
VARIANT 162 162 A -> E (in allele DMB*01:02 and allele
DMB*01:06; dbSNP:rs2071555).
/FTId=VAR_016753.
VARIANT 162 162 A -> V (in allele DMB*01:04 and allele
DMB*01:05; dbSNP:rs2071555).
/FTId=VAR_016754.
VARIANT 197 197 I -> T (in allele DMB*01:03, allele
DMB*01:04 and allele DMB*01:06;
dbSNP:rs1042337).
{ECO:0000269|PubMed:14574404}.
/FTId=VAR_016755.
MUTAGEN 248 248 Y->A: Abolishes targeting to endosomes
and results in relocalization to the cell
membrane. {ECO:0000269|PubMed:8757605}.
MUTAGEN 251 251 L->A: Abolishes targeting to endosomes
and results in relocalization to the cell
membrane. {ECO:0000269|PubMed:8757605}.
STRAND 22 32 {ECO:0000244|PDB:2BC4}.
STRAND 33 35 {ECO:0000244|PDB:4FQX}.
STRAND 37 46 {ECO:0000244|PDB:2BC4}.
STRAND 49 55 {ECO:0000244|PDB:2BC4}.
TURN 56 59 {ECO:0000244|PDB:2BC4}.
STRAND 60 63 {ECO:0000244|PDB:2BC4}.
STRAND 67 69 {ECO:0000244|PDB:4I0P}.
HELIX 70 81 {ECO:0000244|PDB:2BC4}.
HELIX 84 91 {ECO:0000244|PDB:2BC4}.
HELIX 93 109 {ECO:0000244|PDB:2BC4}.
STRAND 116 121 {ECO:0000244|PDB:2BC4}.
STRAND 128 143 {ECO:0000244|PDB:2BC4}.
STRAND 146 151 {ECO:0000244|PDB:2BC4}.
STRAND 154 156 {ECO:0000244|PDB:2BC4}.
STRAND 170 172 {ECO:0000244|PDB:2BC4}.
STRAND 174 182 {ECO:0000244|PDB:2BC4}.
STRAND 190 195 {ECO:0000244|PDB:2BC4}.
STRAND 199 201 {ECO:0000244|PDB:2BC4}.
STRAND 203 207 {ECO:0000244|PDB:2BC4}.
HELIX 212 214 {ECO:0000244|PDB:2BC4}.
SEQUENCE 263 AA; 28943 MW; 9B50F6CC22B3A4BA CRC64;
MITFLPLLLG LSLGCTGAGG FVAHVESTCL LDDAGTPKDF TYCISFNKDL LTCWDPEENK
MAPCEFGVLN SLANVLSQHL NQKDTLMQRL RNGLQNCATH TQPFWGSLTN RTRPPSVQVA
KTTPFNTREP VMLACYVWGF YPAEVTITWR KNGKLVMPHS SAHKTAQPNG DWTYQTLSHL
ALTPSYGDTY TCVVEHIGAP EPILRDWTPG LSPMQTLKVS VSAVTLGLGL IIFSLGVISW
RRAGHSSYTP LPGSNYSEGW HIS


Related products :

Catalog number Product name Quantity
EIAAB11453 DMB,HLA class II histocompatibility antigen, DM beta chain,HLA-DMB,Homo sapiens,Human,MHC class II antigen DMB,Really interesting new gene 7 protein,RING7
EIAAB11449 DMA,HLA class II histocompatibility antigen, DM alpha chain,HLA-DMA,Homo sapiens,Human,MHC class II antigen DMA,Really interesting new gene 6 protein,RING6
EIAAB11729 HLA class II histocompatibility antigen, DP beta 1 chain,HLA class II histocompatibility antigen, DP(W4) beta chain,HLA-DP1B,HLA-DPB1,Homo sapiens,Human,MHC class II antigen DPB1
EIAAB11886 HLA class II histocompatibility antigen, DQ beta 2 chain,HLA class II histocompatibility antigen, DX beta chain,HLA-DQB2,HLA-DXB,Homo sapiens,Human,MHC class II antigen DQB2
EIAAB11640 HLA class II histocompatibility antigen, DO beta chain,HLA-DOB,Homo sapiens,Human,MHC class II antigen DOB
E1386h ELISA kit HLA class I histocompatibility antigen, alpha chain G,HLA G antigen,HLA-6.0,HLAG,HLA-G,Homo sapiens,Human,MHC class I antigen G 96T
U1386h CLIA HLA class I histocompatibility antigen, alpha chain G,HLA G antigen,HLA-6.0,HLAG,HLA-G,Homo sapiens,Human,MHC class I antigen G 96T
E1386h ELISA HLA class I histocompatibility antigen, alpha chain G,HLA G antigen,HLA-6.0,HLAG,HLA-G,Homo sapiens,Human,MHC class I antigen G 96T
E0910m ELISA Class I histocompatibility antigen-like protein,Major histocompatibility complex class I-related gene protein,MHC class I-related gene protein,Mouse,Mr1,Mr1a,Mus musculus 96T
E0910h ELISA kit Class I histocompatibility antigen-like protein,Homo sapiens,Human,Major histocompatibility complex class I-related gene protein,MHC class I-related gene protein,MR1 96T
E0910m ELISA kit Class I histocompatibility antigen-like protein,Major histocompatibility complex class I-related gene protein,MHC class I-related gene protein,Mouse,Mr1,Mr1a,Mus musculus 96T
U0910h CLIA Class I histocompatibility antigen-like protein,Homo sapiens,Human,Major histocompatibility complex class I-related gene protein,MHC class I-related gene protein,MR1 96T
U0910m CLIA Class I histocompatibility antigen-like protein,Major histocompatibility complex class I-related gene protein,MHC class I-related gene protein,Mouse,Mr1,Mr1a,Mus musculus 96T
E0910h ELISA Class I histocompatibility antigen-like protein,Homo sapiens,Human,Major histocompatibility complex class I-related gene protein,MHC class I-related gene protein,MR1 96T
EIAAB11885 HLA class II histocompatibility antigen, DQ beta 1 chain,HLA-DQB,HLA-DQB1,Homo sapiens,Human,MHC class II antigen DQB1
EIAAB11904 HLA class II histocompatibility antigen, DR beta 4 chain,HLA-DRB4,Homo sapiens,Human,MHC class II antigen DRB4
EIAAB11903 HLA class II histocompatibility antigen, DR beta 3 chain,HLA-DRB3,Homo sapiens,Human,MHC class II antigen DRB3
EIAAB11905 DR beta-5,DR2-beta-2,Dw2,HLA class II histocompatibility antigen, DR beta 5 chain,HLA-DRB5,Homo sapiens,Human,MHC class II antigen DRB5
EIAAB11884 DX alpha chain,HLA class II histocompatibility antigen, DQ alpha 2 chain,HLA class II histocompatibility antigen, DQ(6) alpha chain,HLA-DQA1,HLA-DQA2,HLA-DXA,Homo sapiens,Human,MHC class II DQA2
E1752h ELISA HLA class I histocompatibility antigen, alpha chain E,HLA-6.2,HLAE,HLA-E,Homo sapiens,Human,MHC class I antigen E 96T
E1752h ELISA kit HLA class I histocompatibility antigen, alpha chain E,HLA-6.2,HLAE,HLA-E,Homo sapiens,Human,MHC class I antigen E 96T
U1752h CLIA HLA class I histocompatibility antigen, alpha chain E,HLA-6.2,HLAE,HLA-E,Homo sapiens,Human,MHC class I antigen E 96T
EIAAB11895 HLA class II histocompatibility antigen, DR alpha chain,HLA-DRA,HLA-DRA1,Homo sapiens,Human,MHC class II antigen DRA
HB21_MOUSE ELISA Kit FOR H-2 class II histocompatibility antigen, E-B beta chain; organism: Mouse; gene name: H2-Eb1 96T
HB2I_MOUSE ELISA Kit FOR H-2 class II histocompatibility antigen, I-A beta chain; organism: Mouse; gene name: H2-Eb1 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur