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HMGI family protein HMGI-C

 Q76M67_CAPHI            Unreviewed;       109 AA.
Q76M67;
05-JUL-2004, integrated into UniProtKB/TrEMBL.
05-JUL-2004, sequence version 1.
07-JUN-2017, entry version 53.
SubName: Full=HMGI family protein HMGI-C {ECO:0000313|EMBL:BAB64336.1};
Name=HMGI-C {ECO:0000313|EMBL:BAB64336.1};
Capra hircus (Goat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Caprinae; Capra.
NCBI_TaxID=9925 {ECO:0000313|EMBL:BAB64336.1};
[1] {ECO:0000313|EMBL:BAB64336.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Shiba goat {ECO:0000313|EMBL:BAB64336.1};
TISSUE=Placenta {ECO:0000313|EMBL:BAB64336.1};
Tachi C., Nakatani Y., Yoshida K., Tanaka M., Maruyama M., Akiyama M.,
Narita T., Miyazaki H., Hirayama T., Saburi S.;
"Expression of HMGI-C in caprine trophoblast cell line HTS-1 and
molecular cloning of caprine HMGI-C cDNA.";
Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
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EMBL; AB058681; BAB64336.1; -; mRNA.
RefSeq; NP_001272580.1; NM_001285651.1.
UniGene; Chi.38818; -.
ProteinModelPortal; Q76M67; -.
GeneID; 100860792; -.
KEGG; chx:100860792; -.
CTD; 8091; -.
HOVERGEN; HBG051913; -.
KO; K09283; -.
GO; GO:0000228; C:nuclear chromosome; ISS:UniProtKB.
GO; GO:0005634; C:nucleus; ISS:UniProtKB.
GO; GO:0032993; C:protein-DNA complex; ISS:UniProtKB.
GO; GO:0035985; C:senescence-associated heterochromatin focus; ISS:UniProtKB.
GO; GO:0071141; C:SMAD protein complex; ISS:UniProtKB.
GO; GO:0051575; F:5'-deoxyribose-5-phosphate lyase activity; ISS:UniProtKB.
GO; GO:0003680; F:AT DNA binding; ISS:UniProtKB.
GO; GO:0070742; F:C2H2 zinc finger domain binding; ISS:UniProtKB.
GO; GO:0035497; F:cAMP response element binding; ISS:UniProtKB.
GO; GO:0001047; F:core promoter binding; ISS:UniProtKB.
GO; GO:0008301; F:DNA binding, bending; ISS:UniProtKB.
GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; ISS:UniProtKB.
GO; GO:0004677; F:DNA-dependent protein kinase activity; ISS:UniProtKB.
GO; GO:0035501; F:MH1 domain binding; ISS:UniProtKB.
GO; GO:0035500; F:MH2 domain binding; ISS:UniProtKB.
GO; GO:0031492; F:nucleosomal DNA binding; ISS:UniProtKB.
GO; GO:0000975; F:regulatory region DNA binding; ISS:UniProtKB.
GO; GO:0001078; F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; ISS:UniProtKB.
GO; GO:0006284; P:base-excision repair; ISS:UniProtKB.
GO; GO:0002062; P:chondrocyte differentiation; ISS:UniProtKB.
GO; GO:0035988; P:chondrocyte proliferation; ISS:UniProtKB.
GO; GO:0031052; P:chromosome breakage; ISS:UniProtKB.
GO; GO:0042769; P:DNA damage response, detection of DNA damage; ISS:UniProtKB.
GO; GO:0035987; P:endodermal cell differentiation; ISS:UniProtKB.
GO; GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.
GO; GO:0045444; P:fat cell differentiation; ISS:UniProtKB.
GO; GO:0031507; P:heterochromatin assembly; ISS:UniProtKB.
GO; GO:0035978; P:histone H2A-S139 phosphorylation; ISS:UniProtKB.
GO; GO:0048762; P:mesenchymal cell differentiation; ISS:UniProtKB.
GO; GO:0048333; P:mesodermal cell differentiation; ISS:UniProtKB.
GO; GO:0003131; P:mesodermal-endodermal cell signaling; ISS:UniProtKB.
GO; GO:0007095; P:mitotic G2 DNA damage checkpoint; ISS:UniProtKB.
GO; GO:0043922; P:negative regulation by host of viral transcription; ISS:UniProtKB.
GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
GO; GO:0043392; P:negative regulation of DNA binding; ISS:UniProtKB.
GO; GO:2001033; P:negative regulation of double-strand break repair via nonhomologous end joining; ISS:UniProtKB.
GO; GO:0045869; P:negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; ISS:UniProtKB.
GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
GO; GO:0090402; P:oncogene-induced cell senescence; ISS:UniProtKB.
GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
GO; GO:0071158; P:positive regulation of cell cycle arrest; ISS:UniProtKB.
GO; GO:2000685; P:positive regulation of cellular response to X-ray; ISS:UniProtKB.
GO; GO:2000774; P:positive regulation of cellular senescence; ISS:UniProtKB.
GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
GO; GO:2001022; P:positive regulation of response to DNA damage stimulus; ISS:UniProtKB.
GO; GO:2000648; P:positive regulation of stem cell proliferation; ISS:UniProtKB.
GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
GO; GO:2000679; P:positive regulation of transcription regulatory region DNA binding; ISS:UniProtKB.
GO; GO:0010564; P:regulation of cell cycle process; ISS:UniProtKB.
GO; GO:2001038; P:regulation of cellular response to drug; ISS:UniProtKB.
GO; GO:2000036; P:regulation of stem cell population maintenance; ISS:UniProtKB.
GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
GO; GO:0035986; P:senescence-associated heterochromatin focus assembly; ISS:UniProtKB.
InterPro; IPR017956; AT_hook_DNA-bd_motif.
InterPro; IPR000116; HMGA.
InterPro; IPR000637; HMGI/Y_DNA-bd_CS.
Pfam; PF02178; AT_hook; 3.
PRINTS; PR00929; ATHOOK.
PRINTS; PR00930; HIGHMOBLTYIY.
SMART; SM00384; AT_hook; 3.
PROSITE; PS00354; HMGI_Y; 1.
2: Evidence at transcript level;
SEQUENCE 109 AA; 11832 MW; F36BABE623DA4615 CRC64;
MSARGEGAGQ PSTSAQGQPA APAPQKRGRG RPRKQQQEPT GEPSPKRPRG RPKGSKNKSP
SKAAQKKAEA TGEKRPRGRP RKWPQQVVQK KPAQEETEET SSQESAEED


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