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HOXD8

 I7AK88_POLSP            Unreviewed;       245 AA.
I7AK88;
03-OCT-2012, integrated into UniProtKB/TrEMBL.
03-OCT-2012, sequence version 1.
22-NOV-2017, entry version 32.
SubName: Full=HOXD8 {ECO:0000313|EMBL:AFO42769.1};
Name=HOXD8 {ECO:0000313|EMBL:AFO42769.1};
Polyodon spathula (North American paddlefish) (Squalus spathula).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Chondrostei; Acipenseriformes; Polyodontidae;
Polyodon.
NCBI_TaxID=7913 {ECO:0000313|EMBL:AFO42769.1};
[1] {ECO:0000313|EMBL:AFO42769.1}
NUCLEOTIDE SEQUENCE.
PubMed=22851613;
Crow K.D., Smith C.D., Cheng J.F., Wagner G.P., Amemiya C.T.;
"An independent genome duplication inferred from hox paralogs in the
american paddlefish--a representative Basal ray-finned fish and
important comparative reference.";
Genome Biol. Evol. 4:825-841(2012).
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
ProRule:PRU00108, ECO:0000256|RuleBase:RU004442,
ECO:0000256|SAAS:SAAS00860360}.
-!- SIMILARITY: Belongs to the Antp homeobox family.
{ECO:0000256|RuleBase:RU004442, ECO:0000256|SAAS:SAAS00860374}.
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EMBL; JX280945; AFO42769.1; -; Genomic_DNA.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:InterPro.
GO; GO:0007275; P:multicellular organism development; IEA:UniProtKB-KW.
CDD; cd00086; homeodomain; 1.
InterPro; IPR009057; Homeobox-like_sf.
InterPro; IPR017995; Homeobox_antennapedia.
InterPro; IPR001827; Homeobox_Antennapedia_CS.
InterPro; IPR017970; Homeobox_CS.
InterPro; IPR001356; Homeobox_dom.
InterPro; IPR020479; Homeobox_metazoa.
InterPro; IPR000047; HTH_motif.
Pfam; PF00046; Homeobox; 1.
PRINTS; PR00025; ANTENNAPEDIA.
PRINTS; PR00024; HOMEOBOX.
PRINTS; PR00031; HTHREPRESSR.
SMART; SM00389; HOX; 1.
SUPFAM; SSF46689; SSF46689; 1.
PROSITE; PS00032; ANTENNAPEDIA; 1.
PROSITE; PS00027; HOMEOBOX_1; 1.
PROSITE; PS50071; HOMEOBOX_2; 1.
3: Inferred from homology;
Developmental protein {ECO:0000256|SAAS:SAAS00860310};
DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU004442, ECO:0000256|SAAS:SAAS00860283};
Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU004442, ECO:0000256|SAAS:SAAS00860291};
Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU004442, ECO:0000256|SAAS:SAAS00860284}.
DOMAIN 151 211 Homeobox. {ECO:0000259|PROSITE:PS50071}.
DNA_BIND 153 212 Homeobox. {ECO:0000256|PROSITE-
ProRule:PRU00108}.
SEQUENCE 245 AA; 28407 MW; A68010F975C63061 CRC64;
MSSYFVNPFY PKYKAAETIG TTYYDCQFPR DINSRHTVMY GSSASFQHPT KVQEFYHHGT
SAIPNGGYQP NPCGITCHVD PSKFYGYHNL QRQQFFTTQQ ETELVQYPDC KSSSSNTGEE
PEHLNQNSSP SQMFPWMRPQ GCSCVSFVIA PGRRRGRQTY TRFQTLELEK GFIFNPYLTR
KRRIEVSHAL GLTERQVKIW FQNRRMKWKK ENNKDKFPSS LPKDGEEVKM EPGNSVQHKT
GNDTA


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