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Hairy/enhancer-of-split related with YRPW motif protein 2 (Cardiovascular helix-loop-helix factor 1) (hCHF1) (Class B basic helix-loop-helix protein 32) (bHLHb32) (HES-related repressor protein 2) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HRT-2) (hHRT2) (Protein gridlock homolog)

 HEY2_HUMAN              Reviewed;         337 AA.
Q9UBP5;
11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
01-MAY-2000, sequence version 1.
22-NOV-2017, entry version 147.
RecName: Full=Hairy/enhancer-of-split related with YRPW motif protein 2;
AltName: Full=Cardiovascular helix-loop-helix factor 1;
Short=hCHF1;
AltName: Full=Class B basic helix-loop-helix protein 32;
Short=bHLHb32;
AltName: Full=HES-related repressor protein 2;
AltName: Full=Hairy and enhancer of split-related protein 2;
Short=HESR-2;
AltName: Full=Hairy-related transcription factor 2;
Short=HRT-2;
Short=hHRT2;
AltName: Full=Protein gridlock homolog;
Name=HEY2; Synonyms=BHLHB32, CHF1, GRL, HERP, HERP1, HRT2;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
PubMed=10415358; DOI=10.1016/S0925-4773(99)00080-5;
Leimeister C., Externbrinck A., Klamt B., Gessler M.;
"Hey genes: a novel subfamily of hairy- and enhancer of split related
genes specifically expressed during mouse embryogenesis.";
Mech. Dev. 85:173-177(1999).
[2]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Heart;
PubMed=10710309; DOI=10.1126/science.287.5459.1820;
Zhong T.P., Rosenberg M., Mohideen M.-A.P.K., Weinstein B.,
Fishman M.C.;
"Gridlock, an HLH gene required for assembly of the aorta in
zebrafish.";
Science 287:1820-1824(2000).
[3]
NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND INTERACTION WITH ARNT.
TISSUE=Heart;
PubMed=10692439; DOI=10.1074/jbc.275.9.6381;
Chin M.T., Maemura K., Fukumoto S., Jain M.K., Layne M.D.,
Watanabe M., Hsieh C.-M., Lee M.-E.;
"Cardiovascular basic helix loop helix factor 1, a novel
transcriptional repressor expressed preferentially in the developing
and adult cardiovascular system.";
J. Biol. Chem. 275:6381-6387(2000).
[4]
NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND DNA-BINDING.
PubMed=11095750; DOI=10.1073/pnas.250485597;
Nakagawa O., McFadden D.G., Nakagawa M., Yanagisawa H., Hu T.,
Srivastava D., Olson E.N.;
"Members of the HRT family of basic helix-loop-helix proteins act as
transcriptional repressors downstream of Notch signaling.";
Proc. Natl. Acad. Sci. U.S.A. 97:13655-13660(2000).
[5]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Heart;
PubMed=11486044; DOI=10.1128/MCB.21.17.6071-6079.2001;
Iso T., Sartorelli V., Chung G., Shichinohe T., Kedes L., Hamamori Y.;
"HERP, a new primary target of Notch regulated by ligand binding.";
Mol. Cell. Biol. 21:6071-6079(2001).
[6]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Testis;
Tanaka K., Miyata J., Ikeda J.;
"Homo sapiens testis cDNA clone, basic-helix-loop-helix protein
(Hey2).";
Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
[7]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,
Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,
Phelan M., Farmer A.;
"Cloning of human full-length CDSs in BD Creator(TM) system donor
vector.";
Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
[8]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=14574404; DOI=10.1038/nature02055;
Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
"The DNA sequence and analysis of human chromosome 6.";
Nature 425:805-811(2003).
[9]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Lung;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[10]
FUNCTION.
PubMed=15485867; DOI=10.1074/jbc.M409879200;
Kathiriya I.S., King I.N., Murakami M., Nakagawa M., Astle J.M.,
Gardner K.A., Gerard R.D., Olson E.N., Srivastava D., Nakagawa O.;
"Hairy-related transcription factors inhibit GATA-dependent cardiac
gene expression through a signal-responsive mechanism.";
J. Biol. Chem. 279:54937-54943(2004).
[11]
FUNCTION, INTERACTION WITH GATA6, AND MUTAGENESIS OF GLY-54.
PubMed=16293227; DOI=10.1016/j.bbrc.2005.10.190;
Shirvani S., Xiang F., Koibuchi N., Chin M.T.;
"CHF1/Hey2 suppresses SM-MHC promoter activity through an interaction
with GATA-6.";
Biochem. Biophys. Res. Commun. 339:151-156(2006).
[12]
VARIANTS ALA-96; ALA-98 AND SER-100.
PubMed=16329098; DOI=10.1002/humu.9390;
Reamon-Buettner S.M., Borlak J.;
"HEY2 mutations in malformed hearts.";
Hum. Mutat. 27:118-118(2006).
-!- FUNCTION: Downstream effector of Notch signaling which may be
required for cardiovascular development. Transcriptional repressor
which binds preferentially to the canonical E box sequence 5'-
CACGTG-3'. Represses transcription by the cardiac transcriptional
activators GATA4 and GATA6. {ECO:0000269|PubMed:10692439,
ECO:0000269|PubMed:11095750, ECO:0000269|PubMed:15485867,
ECO:0000269|PubMed:16293227}.
-!- SUBUNIT: May self-associate (By similarity). Interacts with GATA4,
HES1 and HEYL (By similarity). Interacts with HDAC1, NCOR1 and
SIN3A (By similarity). Interacts with ARNT and GATA6.
{ECO:0000250, ECO:0000269|PubMed:10692439,
ECO:0000269|PubMed:16293227}.
-!- INTERACTION:
P42858:HTT; NbExp=2; IntAct=EBI-750630, EBI-466029;
Q9BYR3:KRTAP4-4; NbExp=4; IntAct=EBI-750630, EBI-11958132;
Q93062:RBPMS; NbExp=3; IntAct=EBI-750630, EBI-740322;
Q96EB6:SIRT1; NbExp=3; IntAct=EBI-750630, EBI-1802965;
Q13077:TRAF1; NbExp=5; IntAct=EBI-750630, EBI-359224;
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-
ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}.
-!- SIMILARITY: Belongs to the HEY family. {ECO:0000305}.
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EMBL; AJ249545; CAB56839.1; -; mRNA.
EMBL; AF237949; AAF44781.1; -; mRNA.
EMBL; AF173901; AAF20173.1; -; mRNA.
EMBL; AF311884; AAG31157.1; -; mRNA.
EMBL; AF232238; AAF37296.1; -; mRNA.
EMBL; AB044755; BAA96781.1; -; mRNA.
EMBL; BT020067; AAV38870.1; -; mRNA.
EMBL; BT020068; AAV38871.1; -; mRNA.
EMBL; AL078594; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; BC007707; AAH07707.1; -; mRNA.
CCDS; CCDS5131.1; -.
RefSeq; NP_036391.1; NM_012259.2.
UniGene; Hs.144287; -.
ProteinModelPortal; Q9UBP5; -.
SMR; Q9UBP5; -.
BioGrid; 117045; 25.
CORUM; Q9UBP5; -.
ELM; Q9UBP5; -.
IntAct; Q9UBP5; 18.
MINT; MINT-1469894; -.
STRING; 9606.ENSP00000357348; -.
iPTMnet; Q9UBP5; -.
PhosphoSitePlus; Q9UBP5; -.
BioMuta; HEY2; -.
DMDM; 74762767; -.
PaxDb; Q9UBP5; -.
PeptideAtlas; Q9UBP5; -.
PRIDE; Q9UBP5; -.
DNASU; 23493; -.
Ensembl; ENST00000368364; ENSP00000357348; ENSG00000135547.
GeneID; 23493; -.
KEGG; hsa:23493; -.
UCSC; uc003qad.4; human.
CTD; 23493; -.
DisGeNET; 23493; -.
EuPathDB; HostDB:ENSG00000135547.8; -.
GeneCards; HEY2; -.
HGNC; HGNC:4881; HEY2.
HPA; HPA030205; -.
HPA; HPA074851; -.
MIM; 604674; gene.
neXtProt; NX_Q9UBP5; -.
OpenTargets; ENSG00000135547; -.
PharmGKB; PA29259; -.
eggNOG; KOG4304; Eukaryota.
eggNOG; ENOG4111F0X; LUCA.
GeneTree; ENSGT00700000104130; -.
HOGENOM; HOG000286035; -.
HOVERGEN; HBG003275; -.
InParanoid; Q9UBP5; -.
KO; K09091; -.
OMA; STCASQR; -.
OrthoDB; EOG091G0HNC; -.
PhylomeDB; Q9UBP5; -.
TreeFam; TF323617; -.
Reactome; R-HSA-2122947; NOTCH1 Intracellular Domain Regulates Transcription.
Reactome; R-HSA-2644606; Constitutive Signaling by NOTCH1 PEST Domain Mutants.
Reactome; R-HSA-2894862; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants.
Reactome; R-HSA-8940973; RUNX2 regulates osteoblast differentiation.
SIGNOR; Q9UBP5; -.
GeneWiki; HEY2; -.
GenomeRNAi; 23493; -.
PRO; PR:Q9UBP5; -.
Proteomes; UP000005640; Chromosome 6.
Bgee; ENSG00000135547; -.
CleanEx; HS_HEY2; -.
ExpressionAtlas; Q9UBP5; baseline and differential.
Genevisible; Q9UBP5; HS.
GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO; GO:0005654; C:nucleoplasm; TAS:Reactome.
GO; GO:0005634; C:nucleus; ISS:UniProtKB.
GO; GO:0017053; C:transcriptional repressor complex; IDA:BHF-UCL.
GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
GO; GO:0035939; F:microsatellite binding; IDA:UniProtKB.
GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
GO; GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
GO; GO:0000988; F:transcription factor activity, protein binding; IDA:UniProtKB.
GO; GO:0000983; F:transcription factor activity, RNA polymerase II core promoter sequence-specific; ISS:UniProtKB.
GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IDA:UniProtKB.
GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
GO; GO:0060842; P:arterial endothelial cell differentiation; ISS:BHF-UCL.
GO; GO:0035910; P:ascending aorta morphogenesis; ISS:BHF-UCL.
GO; GO:0060413; P:atrial septum morphogenesis; ISS:BHF-UCL.
GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; ISS:BHF-UCL.
GO; GO:0003214; P:cardiac left ventricle morphogenesis; ISS:BHF-UCL.
GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IEA:Ensembl.
GO; GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.
GO; GO:0060411; P:cardiac septum morphogenesis; ISS:BHF-UCL.
GO; GO:0060948; P:cardiac vascular smooth muscle cell development; IEA:Ensembl.
GO; GO:0003208; P:cardiac ventricle morphogenesis; ISS:UniProtKB.
GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
GO; GO:0090102; P:cochlea development; IEA:Ensembl.
GO; GO:0060977; P:coronary vasculature morphogenesis; IEA:Ensembl.
GO; GO:0035912; P:dorsal aorta morphogenesis; ISS:BHF-UCL.
GO; GO:0003199; P:endocardial cushion to mesenchymal transition involved in heart valve formation; IEA:Ensembl.
GO; GO:0060347; P:heart trabecula formation; IEA:Ensembl.
GO; GO:0060716; P:labyrinthine layer blood vessel development; ISS:BHF-UCL.
GO; GO:0014031; P:mesenchymal cell development; ISS:BHF-UCL.
GO; GO:0003150; P:muscular septum morphogenesis; ISS:BHF-UCL.
GO; GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IEA:Ensembl.
GO; GO:2000723; P:negative regulation of cardiac vascular smooth muscle cell differentiation; ISS:BHF-UCL.
GO; GO:0010629; P:negative regulation of gene expression; ISS:UniProtKB.
GO; GO:0045746; P:negative regulation of Notch signaling pathway; IEA:Ensembl.
GO; GO:0010621; P:negative regulation of transcription by transcription factor localization; ISS:BHF-UCL.
GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
GO; GO:2000820; P:negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; ISS:BHF-UCL.
GO; GO:0060633; P:negative regulation of transcription initiation from RNA polymerase II promoter; IDA:BHF-UCL.
GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.
GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
GO; GO:0061314; P:Notch signaling involved in heart development; IC:BHF-UCL.
GO; GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.
GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IEA:Ensembl.
GO; GO:0010460; P:positive regulation of heart rate; IEA:Ensembl.
GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
GO; GO:0065004; P:protein-DNA complex assembly; IEA:Ensembl.
GO; GO:0061156; P:pulmonary artery morphogenesis; ISS:BHF-UCL.
GO; GO:0003184; P:pulmonary valve morphogenesis; ISS:BHF-UCL.
GO; GO:0045607; P:regulation of auditory receptor cell differentiation; IEA:Ensembl.
GO; GO:2001212; P:regulation of vasculogenesis; ISS:BHF-UCL.
GO; GO:0051145; P:smooth muscle cell differentiation; NAS:BHF-UCL.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
GO; GO:0003195; P:tricuspid valve formation; IEA:Ensembl.
GO; GO:0003186; P:tricuspid valve morphogenesis; ISS:BHF-UCL.
GO; GO:0036304; P:umbilical cord morphogenesis; ISS:BHF-UCL.
GO; GO:0097084; P:vascular smooth muscle cell development; IEP:UniProtKB.
GO; GO:0001570; P:vasculogenesis; ISS:BHF-UCL.
GO; GO:0055015; P:ventricular cardiac muscle cell development; ISS:UniProtKB.
GO; GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL.
GO; GO:0003222; P:ventricular trabecula myocardium morphogenesis; IEA:Ensembl.
CDD; cd00083; HLH; 1.
Gene3D; 4.10.280.10; -; 1.
InterPro; IPR011598; bHLH_dom.
InterPro; IPR036638; HLH_DNA-bd_sf.
InterPro; IPR003650; Orange_dom.
Pfam; PF07527; Hairy_orange; 1.
Pfam; PF00010; HLH; 1.
SMART; SM00353; HLH; 1.
SMART; SM00511; ORANGE; 1.
SUPFAM; SSF47459; SSF47459; 1.
PROSITE; PS50888; BHLH; 1.
PROSITE; PS51054; ORANGE; 1.
1: Evidence at protein level;
Complete proteome; Developmental protein; DNA-binding;
Notch signaling pathway; Nucleus; Polymorphism; Reference proteome;
Repressor; Transcription; Transcription regulation.
CHAIN 1 337 Hairy/enhancer-of-split related with YRPW
motif protein 2.
/FTId=PRO_0000245515.
DOMAIN 48 103 bHLH. {ECO:0000255|PROSITE-
ProRule:PRU00981}.
DOMAIN 122 157 Orange. {ECO:0000255|PROSITE-
ProRule:PRU00380}.
REGION 47 116 Transcriptional repression and
interaction with NCOR1 and SIN3A.
{ECO:0000250}.
MOTIF 327 330 YRPW motif.
COMPBIAS 175 191 His-rich.
COMPBIAS 262 302 Ala-rich.
VARIANT 96 96 T -> A (in a patient with
atrioventricular septal defects;
dbSNP:rs747221103).
{ECO:0000269|PubMed:16329098}.
/FTId=VAR_026974.
VARIANT 98 98 D -> A (in a patient with
atrioventricular septal defects).
{ECO:0000269|PubMed:16329098}.
/FTId=VAR_026975.
VARIANT 100 100 L -> S (in a patient with
atrioventricular septal defects).
{ECO:0000269|PubMed:16329098}.
/FTId=VAR_026976.
VARIANT 140 140 V -> M (in dbSNP:rs3734638).
/FTId=VAR_026977.
MUTAGEN 54 54 G->P: Impairs transcriptional repression.
{ECO:0000269|PubMed:16293227}.
SEQUENCE 337 AA; 35808 MW; 71B7B1AA69BA88D2 CRC64;
MKRPCEETTS ESDMDETIDV GSENNYSGQS TSSVIRLNSP TTTSQIMARK KRRGIIEKRR
RDRINNSLSE LRRLVPTAFE KQGSAKLEKA EILQMTVDHL KMLQATGGKG YFDAHALAMD
FMSIGFRECL TEVARYLSSV EGLDSSDPLR VRLVSHLSTC ATQREAAAMT SSMAHHHHPL
HPHHWAAAFH HLPAALLQPN GLHASESTPC RLSTTSEVPP AHGSALLTAT FAHADSALRM
PSTGSVAPCV PPLSTSLLSL SATVHAAAAA ATAAAHSFPL SFAGAFPMLP PNAAAAVAAA
TAISPPLSVS ATSSPQQTSS GTNNKPYRPW GTEVGAF


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E2004h ELISA Basic-helix-loop-helix-PAS protein MOP2,bHLHe73,BHLHE73,Class E basic helix-loop-helix protein 73,Endothelial PAS domain-containing protein 1,EPAS1,EPAS-1,HIF-1-alpha-like factor,HIF2A,HIF-2-alp 96T
E0255h ELISA ATH1,ATOH1,bHLHa14,BHLHA14,Class A basic helix-loop-helix protein 14,hATH1,Helix-loop-helix protein hATH-1,Homo sapiens,Human,Protein atonal homolog 1 96T
E0255h ELISA kit ATH1,ATOH1,bHLHa14,BHLHA14,Class A basic helix-loop-helix protein 14,hATH1,Helix-loop-helix protein hATH-1,Homo sapiens,Human,Protein atonal homolog 1 96T
U0255h CLIA ATH1,ATOH1,bHLHa14,BHLHA14,Class A basic helix-loop-helix protein 14,hATH1,Helix-loop-helix protein hATH-1,Homo sapiens,Human,Protein atonal homolog 1 96T
E0520h Dog ELISA Kit FOR Hairy per enhancer-of-split related with YRPW motif protein 1 96T
NEDD8_RAT Dog ELISA Kit FOR Hairy per enhancer-of-split related with YRPW motif protein 1 96T
EIAAB28828 bHLHb7,BHLHB7,bHLHe20,BHLHE20,Class B basic helix-loop-helix protein 7,Class E basic helix-loop-helix protein 20,Homo sapiens,Human,OLIG3,Oligo3,Oligodendrocyte transcription factor 3
EIAAB28821 bHLHb6,BHLHB6,bHLHe21,BHLHE21,Class B basic helix-loop-helix protein 6,Class E basic helix-loop-helix protein 21,Homo sapiens,Human,OLIG1,Oligo1,Oligodendrocyte transcription factor 1
CLCB_HUMAN Human ELISA Kit FOR Hairy per enhancer-of-split related with YRPW motif protein 2 96T
MBNL3_HUMAN Human ELISA Kit FOR Hairy per enhancer-of-split related with YRPW motif protein 2 96T
E1025c Human ELISA Kit FOR Hairy per enhancer-of-split related with YRPW motif-like protein 96T
E0273r Human ELISA Kit FOR Hairy per enhancer-of-split related with YRPW motif protein 2 96T
HEY1_MOUSE Mouse ELISA Kit FOR Hairy per enhancer-of-split related with YRPW motif protein 1 96T


 

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