Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Heat shock factor protein (HSF) (Heat shock transcription factor) (HSTF)

 HSF_KLULA               Reviewed;         677 AA.
P22121;
01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
01-AUG-1991, sequence version 1.
23-MAY-2018, entry version 124.
RecName: Full=Heat shock factor protein;
Short=HSF;
AltName: Full=Heat shock transcription factor;
Short=HSTF;
Name=HSF; OrderedLocusNames=KLLA0D03322g;
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC
1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
NCBI_TaxID=284590;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=1899375;
Jakobsen B.K., Pelham H.R.B.;
"A conserved heptapeptide restrains the activity of the yeast heat
shock transcription factor.";
EMBO J. 10:369-375(1991).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 /
WM37;
PubMed=15229592; DOI=10.1038/nature02579;
Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S.,
Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E.,
Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V.,
Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C.,
Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A.,
Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A.,
Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R.,
Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H.,
Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O.,
Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A.,
Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B.,
Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A.,
Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
Wincker P., Souciet J.-L.;
"Genome evolution in yeasts.";
Nature 430:35-44(2004).
[3]
X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS).
PubMed=8284672; DOI=10.1126/science.8284672;
Harrison C.J., Bohm A.A., Nelson H.C.M.;
"Crystal structure of the DNA binding domain of the heat shock
transcription factor.";
Science 263:224-227(1994).
-!- FUNCTION: DNA-binding protein that specifically binds heat shock
promoter elements (HSE) and activates transcription. Also required
for growth at normal temperatures.
-!- SUBUNIT: Homotrimer.
-!- SUBCELLULAR LOCATION: Nucleus.
-!- PTM: Exhibits temperature-dependent phosphorylation.
-!- SIMILARITY: Belongs to the HSF family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; X55149; CAA38950.1; -; Genomic_DNA.
EMBL; CR382124; CAH00310.1; -; Genomic_DNA.
PIR; S13365; S13365.
RefSeq; XP_453214.1; XM_453214.1.
PDB; 1FBQ; X-ray; 2.00 A; A/B=195-281.
PDB; 1FBS; X-ray; 2.00 A; A/B=195-281.
PDB; 1FBU; X-ray; 2.00 A; A/B=195-281.
PDB; 1FYK; X-ray; 2.50 A; A=193-284.
PDB; 1FYL; X-ray; 2.10 A; A/B=193-284.
PDB; 1FYM; X-ray; 2.20 A; A/B=193-284.
PDB; 2HTS; X-ray; 1.83 A; A=193-281.
PDB; 3HSF; NMR; -; A=193-281.
PDB; 3HTS; X-ray; 1.75 A; B=193-281.
PDBsum; 1FBQ; -.
PDBsum; 1FBS; -.
PDBsum; 1FBU; -.
PDBsum; 1FYK; -.
PDBsum; 1FYL; -.
PDBsum; 1FYM; -.
PDBsum; 2HTS; -.
PDBsum; 3HSF; -.
PDBsum; 3HTS; -.
DisProt; DP00036; -.
ProteinModelPortal; P22121; -.
SMR; P22121; -.
STRING; 284590.XP_453214.1; -.
EnsemblFungi; CAH00310; CAH00310; KLLA0_D03322g.
GeneID; 2893291; -.
KEGG; kla:KLLA0D03322g; -.
eggNOG; KOG0627; Eukaryota.
eggNOG; COG5169; LUCA.
InParanoid; P22121; -.
KO; K09419; -.
OrthoDB; EOG092C2G9O; -.
EvolutionaryTrace; P22121; -.
Proteomes; UP000000598; Chromosome D.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0032993; C:protein-DNA complex; IMP:CAFA.
GO; GO:0003677; F:DNA binding; IMP:CAFA.
GO; GO:0003700; F:DNA binding transcription factor activity; IEA:InterPro.
GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
Gene3D; 1.10.10.10; -; 1.
InterPro; IPR000232; HSF_DNA-bd.
InterPro; IPR027725; HSF_fam.
InterPro; IPR036388; WH-like_DNA-bd_sf.
InterPro; IPR036390; WH_DNA-bd_sf.
PANTHER; PTHR10015; PTHR10015; 1.
Pfam; PF00447; HSF_DNA-bind; 1.
PRINTS; PR00056; HSFDOMAIN.
SMART; SM00415; HSF; 1.
SUPFAM; SSF46785; SSF46785; 1.
PROSITE; PS00434; HSF_DOMAIN; 1.
1: Evidence at protein level;
3D-structure; Activator; Complete proteome; DNA-binding; Nucleus;
Phosphoprotein; Reference proteome; Stress response; Transcription;
Transcription regulation.
CHAIN 1 677 Heat shock factor protein.
/FTId=PRO_0000124579.
DNA_BIND 194 299 {ECO:0000250}.
REGION 320 372 Involved in trimerization. {ECO:0000250}.
REGION 466 677 Activatory.
COMPBIAS 458 465 Poly-Ser.
COMPBIAS 485 498 Poly-Gln.
HELIX 196 206 {ECO:0000244|PDB:3HTS}.
HELIX 208 210 {ECO:0000244|PDB:3HTS}.
TURN 211 213 {ECO:0000244|PDB:3HTS}.
STRAND 214 216 {ECO:0000244|PDB:3HTS}.
STRAND 218 221 {ECO:0000244|PDB:1FBQ}.
STRAND 222 226 {ECO:0000244|PDB:3HTS}.
HELIX 228 234 {ECO:0000244|PDB:3HTS}.
HELIX 236 239 {ECO:0000244|PDB:3HTS}.
STRAND 240 242 {ECO:0000244|PDB:1FBS}.
HELIX 245 254 {ECO:0000244|PDB:3HTS}.
STRAND 257 259 {ECO:0000244|PDB:3HTS}.
TURN 266 269 {ECO:0000244|PDB:1FBQ}.
STRAND 276 280 {ECO:0000244|PDB:3HTS}.
SEQUENCE 677 AA; 75420 MW; 0BF03BCF990C210B CRC64;
MGHNDSVETM DEISNPNNIL LPHDGTGLDA TGISGSQEPY GMVDVLNPDS LKDDSNVDEP
LIEDIVNPSL DPEGVVSAEP SNEVGTPLLQ QPISLDHVIT RPASAGGVYS IGNSSTSSAA
KLSDGDLTNA TDPLLNNAHG HGQPSSESQS HSNGYHKQGQ SQQPLLSLNK RKLLAKAHVD
KHHSKKKLST TRARPAFVNK LWSMVNDKSN EKFIHWSTSG ESIVVPNRER FVQEVLPKYF
KHSNFASFVR QLNMYGWHKV QDVKSGSMLS NNDSRWEFEN ENFKRGKEYL LENIVRQKSN
TNILGGTTNA EVDIHILLNE LETVKYNQLA IAEDLKRITK DNEMLWKENM MARERHQSQQ
QVLEKLLRFL SSVFGPNSAK TIGNGFQPDL IHELSDMQVN HMSNNNHNNT GNINPNAYHN
ETDDPMANVF GPLTPTDQGK VPLQDYKLRP RLLLKNRSMS SSSSSNLNQR QSPQNRIVGQ
SPPPQQQQQQ QQQQGQPQGQ QFSYPIQGGN QMMNQLGSPI GTQVGSPVGS QYGNQYGNQY
SNQFGNQLQQ QTSRPALHHG SNGEIRELTP SIVSSDSPDP AFFQDLQNNI DKQEESIQEI
QDWITKLNPG PGEDGNTPIF PELNMPSYFA NTGGSGQSEQ PSDYGDSQIE ELRNSRLHEP
DRSFEEKNNG QKRRRAA


Related products :

Catalog number Product name Quantity
U0435h CLIA Heat shock factor protein 1,Heat shock transcription factor 1,Homo sapiens,HSF 1,HSF1,HSTF 1,HSTF1,Human 96T
E0435h ELISA Heat shock factor protein 1,Heat shock transcription factor 1,Homo sapiens,HSF 1,HSF1,HSTF 1,HSTF1,Human 96T
E0435h ELISA kit Heat shock factor protein 1,Heat shock transcription factor 1,Homo sapiens,HSF 1,HSF1,HSTF 1,HSTF1,Human 96T
E0435m ELISA Heat shock factor protein 1,Heat shock transcription factor 1,HSF 1,Hsf1,HSTF 1,Mouse,Mus musculus 96T
E0435m ELISA kit Heat shock factor protein 1,Heat shock transcription factor 1,HSF 1,Hsf1,HSTF 1,Mouse,Mus musculus 96T
U0435m CLIA Heat shock factor protein 1,Heat shock transcription factor 1,HSF 1,Hsf1,HSTF 1,Mouse,Mus musculus 96T
E0435b ELISA Bos taurus,Bovine,Heat shock factor protein 1,Heat shock transcription factor 1,HSF 1,HSF1,HSTF 1 96T
U0435b CLIA Bos taurus,Bovine,Heat shock factor protein 1,Heat shock transcription factor 1,HSF 1,HSF1,HSTF 1 96T
E0435b ELISA kit Bos taurus,Bovine,Heat shock factor protein 1,Heat shock transcription factor 1,HSF 1,HSF1,HSTF 1 96T
E0435c ELISA kit Chicken,Gallus gallus,Heat shock factor protein 1,Heat shock transcription factor 1,HSF 1,HSF 3A,HSF1,HSTF 1,HSTF 3A 96T
U0435c CLIA Chicken,Gallus gallus,Heat shock factor protein 1,Heat shock transcription factor 1,HSF 1,HSF 3A,HSF1,HSTF 1,HSTF 3A 96T
E0435c ELISA Chicken,Gallus gallus,Heat shock factor protein 1,Heat shock transcription factor 1,HSF 1,HSF 3A,HSF1,HSTF 1,HSTF 3A 96T
18-003-43825 Heat shock factor protein 4 - HSF 4; Heat shock transcription factor 4; HSTF 4; hHSF4 Polyclonal 0.1 mg Protein A
18-003-43943 Heat shock factor protein 1 - HSF 1; Heat shock transcription factor 1; HSTF 1 Polyclonal 0.1 mg Protein A
18-003-43942 Heat shock factor protein 1 - HSF 1; Heat shock transcription factor 1; HSTF 1 Polyclonal 0.05 mg Aff Pur
18-003-43304 Heat shock factor protein 1 - HSF 1; Heat shock transcription factor 1; HSTF 1 Polyclonal 0.05 mg Aff Pur
20-372-60242 heat shock transcription factor 2. mRNA (cDNA clone IMAGE 3684733). complete cds - Mouse monoclonal anti-human HSF2 antibody; HSF 2; Heat shock transcription factor 2; HSTF 2 Monoclonal 0.1 mg
20-372-60110 heat shock transcription factor 1 (HSF1). mRNA - Mouse monoclonal anti-human HSF1 antibody; HSF 1; Heat shock transcription factor 1; HSTF 1 Monoclonal 0.1 mg
18-785-210203 HSF1 (Ab-307) - HSF 1; Heat shock transcription factor 1; HSTF 1 Polyclonal 0.1 mg
18-785-210204 HSF1 (Ab-303) - HSF 1; Heat shock transcription factor 1; HSTF 1 Polyclonal 0.05 mg
18-785-210204 HSF1 (Ab-303) - HSF 1; Heat shock transcription factor 1; HSTF 1 Polyclonal 0.1 mg
18-785-210203 HSF1 (Ab-307) - HSF 1; Heat shock transcription factor 1; HSTF 1 Polyclonal 0.05 mg
27-259 HSF2 binds specifically to the heat-shock element and has homology to HSFs of other species. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stres 0.05 mg
31-175 HSF1 is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and_or associated with multichaperone complexes, is a major r 0.05 mg
18-785-210202 HSF1 (phospho-Ser303) - HSF 1; Heat shock transcription factor 1; HSTF 1 Polyclonal 0.05 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur