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Heat-stable enterotoxin ST (Non O1-ST) (Non-agglutinating cholera vibrios ST) (NAG-ST)

 HSTN_VIBCL              Reviewed;          78 AA.
P0A4M3; P04429;
13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
01-MAR-2005, sequence version 1.
22-NOV-2017, entry version 26.
RecName: Full=Heat-stable enterotoxin ST;
AltName: Full=Non O1-ST;
AltName: Full=Non-agglutinating cholera vibrios ST;
Short=NAG-ST;
Flags: Precursor;
Name=stn;
Vibrio cholerae.
Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
Vibrionaceae; Vibrio.
NCBI_TaxID=666;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=NRT36;
PubMed=2205577;
Ogawa A., Kato J., Watanabe H., Nair B.G., Takeda T.;
"Cloning and nucleotide sequence of a heat-stable enterotoxin gene
from Vibrio cholerae non-O1 isolated from a patient with traveler's
diarrhea.";
Infect. Immun. 58:3325-3329(1990).
[2]
PROTEIN SEQUENCE OF 62-78.
STRAIN=Serovar non-O1;
PubMed=4065341; DOI=10.1016/0014-5793(85)80163-0;
Takao T., Shimonishi Y., Kobayashi M., Nishimura O., Arita M.,
Takeda T., Honda T., Miwatani T.;
"Amino acid sequence of heat-stable enterotoxin produced by Vibrio
cholerae non-01.";
FEBS Lett. 193:250-254(1985).
-!- SUBCELLULAR LOCATION: Secreted.
-!- SIMILARITY: Belongs to the heat-stable enterotoxin family.
{ECO:0000305}.
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EMBL; M85198; AAA64889.1; -; Genomic_DNA.
PIR; A41469; QHVC1.
GO; GO:0005615; C:extracellular space; IEA:InterPro.
GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
InterPro; IPR019806; Heat-stable_enterotox_CS.
InterPro; IPR001489; Heat-stable_enterotox_STa.
Pfam; PF02048; Enterotoxin_ST; 1.
PROSITE; PS00273; ENTEROTOXIN_H_STABLE; 1.
1: Evidence at protein level;
Direct protein sequencing; Disulfide bond; Enterotoxin; Secreted;
Signal; Toxin.
SIGNAL 1 18 {ECO:0000255}.
PROPEP 19 61 {ECO:0000269|PubMed:4065341}.
/FTId=PRO_0000035135.
PEPTIDE 62 78 Heat-stable enterotoxin ST.
/FTId=PRO_0000035136.
DISULFID 64 69 {ECO:0000250}.
DISULFID 65 73 {ECO:0000250}.
DISULFID 68 76 {ECO:0000250}.
SEQUENCE 78 AA; 8830 MW; EED385B298D0964F CRC64;
MRNLFIALML LFSSIAFSQT VENNKKTVQQ PQQIESKVNI KKLSENEECP FIKQVDENGN
LIDCCEICCN PACFGCLN


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