Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Hedgehog protein

 F1P3J4_CHICK            Unreviewed;       425 AA.
F1P3J4;
03-MAY-2011, integrated into UniProtKB/TrEMBL.
03-MAY-2011, sequence version 1.
25-OCT-2017, entry version 58.
RecName: Full=Hedgehog protein {ECO:0000256|RuleBase:RU280812};
Name=SHH {ECO:0000313|Ensembl:ENSGALP00000010292};
Gallus gallus (Chicken).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
Phasianidae; Phasianinae; Gallus.
NCBI_TaxID=9031 {ECO:0000313|Ensembl:ENSGALP00000010292, ECO:0000313|Proteomes:UP000000539};
[1] {ECO:0000313|Ensembl:ENSGALP00000010292, ECO:0000313|Proteomes:UP000000539}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000010292,
ECO:0000313|Proteomes:UP000000539};
PubMed=15592404; DOI=10.1038/nature03154;
International Chicken Genome Sequencing Consortium;
Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C.,
Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E.,
Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W.,
Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A., Kremitzki C.,
Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E.,
Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J.,
Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M.,
Paton B., Smith J., Morrice D., Daniels L., Tempest H.G.,
Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V.,
Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J.,
van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J.,
Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H.,
Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K.,
Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E.,
Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M.,
Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S.,
Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J.,
Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H.,
Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C.,
Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C.,
Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P.,
King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S.,
Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S.,
Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S.,
Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z.,
Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J.,
Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z.,
Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M.,
Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O.,
Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J.,
Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G.,
Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D.,
Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G.,
Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A.,
Mardis E.R., Wilson R.K.;
"Sequence and comparative analysis of the chicken genome provide
unique perspectives on vertebrate evolution.";
Nature 432:695-716(2004).
[2] {ECO:0000313|Ensembl:ENSGALP00000010292}
IDENTIFICATION.
STRAIN=Red jungle fowl {ECO:0000313|Ensembl:ENSGALP00000010292};
Ensembl;
Submitted (JUL-2011) to UniProtKB.
-!- FUNCTION: Intercellular signal essential for a variety of
patterning events during development.
{ECO:0000256|RuleBase:RU280812}.
-!- SIMILARITY: Belongs to the hedgehog family.
{ECO:0000256|RuleBase:RU280812}.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSGALP00000010292}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AADN04000102; -; NOT_ANNOTATED_CDS; Genomic_DNA.
SMR; F1P3J4; -.
PaxDb; F1P3J4; -.
Ensembl; ENSGALT00000010306; ENSGALP00000010292; ENSGALG00000006379.
eggNOG; KOG3638; Eukaryota.
eggNOG; ENOG410XQA3; LUCA.
GeneTree; ENSGT00390000001117; -.
OMA; EHSWAHR; -.
OrthoDB; EOG091G0N90; -.
PhylomeDB; F1P3J4; -.
TreeFam; TF106458; -.
Reactome; R-GGA-5358346; Hedgehog ligand biogenesis.
Reactome; R-GGA-5362798; Release of Hh-Np from the secreting cell.
Reactome; R-GGA-5632681; Ligand-receptor interactions.
Reactome; R-GGA-5635838; Activation of SMO.
Proteomes; UP000000539; Chromosome 2.
Bgee; ENSGALG00000006379; -.
GO; GO:0009986; C:cell surface; IEA:Ensembl.
GO; GO:0005615; C:extracellular space; IDA:AgBase.
GO; GO:0005622; C:intracellular; IEA:GOC.
GO; GO:0045121; C:membrane raft; IEA:Ensembl.
GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
GO; GO:0005578; C:proteinaceous extracellular matrix; IEA:Ensembl.
GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
GO; GO:0005539; F:glycosaminoglycan binding; IEA:Ensembl.
GO; GO:0043237; F:laminin-1 binding; IEA:Ensembl.
GO; GO:0005113; F:patched binding; IEA:Ensembl.
GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-UniRule.
GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
GO; GO:0008209; P:androgen metabolic process; IEA:Ensembl.
GO; GO:0048645; P:animal organ formation; IEA:Ensembl.
GO; GO:0097190; P:apoptotic signaling pathway; IEA:Ensembl.
GO; GO:0060840; P:artery development; IEA:Ensembl.
GO; GO:0060020; P:Bergmann glial cell differentiation; IEA:Ensembl.
GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
GO; GO:0001569; P:branching involved in blood vessel morphogenesis; IEA:Ensembl.
GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
GO; GO:0060447; P:bud outgrowth involved in lung branching; IEA:Ensembl.
GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
GO; GO:0043369; P:CD4-positive or CD8-positive, alpha-beta T cell lineage commitment; IEA:Ensembl.
GO; GO:0001709; P:cell fate determination; NAS:AgBase.
GO; GO:0060573; P:cell fate specification involved in pattern specification; NAS:AgBase.
GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
GO; GO:0021930; P:cerebellar granule cell precursor proliferation; IEA:Ensembl.
GO; GO:0060591; P:chondroblast differentiation; IMP:AgBase.
GO; GO:0071679; P:commissural neuron axon guidance; IMP:AgBase.
GO; GO:0003140; P:determination of left/right asymmetry in lateral mesoderm; IEA:Ensembl.
GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
GO; GO:0007398; P:ectoderm development; IEA:Ensembl.
GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
GO; GO:0048617; P:embryonic foregut morphogenesis; IEA:Ensembl.
GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
GO; GO:0009880; P:embryonic pattern specification; IMP:AgBase.
GO; GO:0060059; P:embryonic retina morphogenesis in camera-type eye; IMP:AgBase.
GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
GO; GO:0006897; P:endocytosis; IEA:Ensembl.
GO; GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; IEA:Ensembl.
GO; GO:0030010; P:establishment of cell polarity; IEA:Ensembl.
GO; GO:0090269; P:fibroblast growth factor production; IDA:AgBase.
GO; GO:0021508; P:floor plate formation; IMP:AgBase.
GO; GO:0048859; P:formation of anatomical boundary; IEA:Ensembl.
GO; GO:0003430; P:growth plate cartilage chondrocyte growth; IMP:AgBase.
GO; GO:0001947; P:heart looping; IEA:Ensembl.
GO; GO:0007442; P:hindgut morphogenesis; IEA:Ensembl.
GO; GO:0048877; P:homeostasis of number of retina cells; IMP:AgBase.
GO; GO:0048839; P:inner ear development; IEA:Ensembl.
GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
GO; GO:0045109; P:intermediate filament organization; IEA:Ensembl.
GO; GO:0060459; P:left lung development; IEA:Ensembl.
GO; GO:0060174; P:limb bud formation; IEA:Ensembl.
GO; GO:0060428; P:lung epithelium development; IEA:Ensembl.
GO; GO:0060463; P:lung lobe morphogenesis; IEA:Ensembl.
GO; GO:0060484; P:lung-associated mesenchyme development; IEA:Ensembl.
GO; GO:0002320; P:lymphoid progenitor cell differentiation; IEA:Ensembl.
GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
GO; GO:0060916; P:mesenchymal cell proliferation involved in lung development; IEA:Ensembl.
GO; GO:0060783; P:mesenchymal smoothened signaling pathway involved in prostate gland development; IEA:Ensembl.
GO; GO:0072136; P:metanephric mesenchymal cell proliferation involved in metanephros development; IEA:Ensembl.
GO; GO:0030901; P:midbrain development; IEA:Ensembl.
GO; GO:0045445; P:myoblast differentiation; IEA:Ensembl.
GO; GO:0014902; P:myotube differentiation; IEA:Ensembl.
GO; GO:0046639; P:negative regulation of alpha-beta T cell differentiation; IEA:Ensembl.
GO; GO:0030514; P:negative regulation of BMP signaling pathway; IMP:AgBase.
GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
GO; GO:0090370; P:negative regulation of cholesterol efflux; IEA:Ensembl.
GO; GO:1904339; P:negative regulation of dopaminergic neuron differentiation; IEA:Ensembl.
GO; GO:2000357; P:negative regulation of kidney smooth muscle cell differentiation; IEA:Ensembl.
GO; GO:2001054; P:negative regulation of mesenchymal cell apoptotic process; IEA:Ensembl.
GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
GO; GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IEA:Ensembl.
GO; GO:2000062; P:negative regulation of ureter smooth muscle cell differentiation; IEA:Ensembl.
GO; GO:0045060; P:negative thymic T cell selection; IEA:Ensembl.
GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
GO; GO:0003408; P:optic cup formation involved in camera-type eye development; IMP:AgBase.
GO; GO:0021631; P:optic nerve morphogenesis; IMP:AgBase.
GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
GO; GO:0060021; P:palate development; IEA:Ensembl.
GO; GO:0031016; P:pancreas development; IEA:Ensembl.
GO; GO:0009949; P:polarity specification of anterior/posterior axis; IEA:Ensembl.
GO; GO:0009951; P:polarity specification of dorsal/ventral axis; NAS:AgBase.
GO; GO:0010694; P:positive regulation of alkaline phosphatase activity; IDA:AgBase.
GO; GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IEA:Ensembl.
GO; GO:0051781; P:positive regulation of cell division; IEA:Ensembl.
GO; GO:0010770; P:positive regulation of cell morphogenesis involved in differentiation; IMP:AgBase.
GO; GO:0060769; P:positive regulation of epithelial cell proliferation involved in prostate gland development; IEA:Ensembl.
GO; GO:0010628; P:positive regulation of gene expression; IMP:AgBase.
GO; GO:0007228; P:positive regulation of hh target transcription factor activity; IEA:Ensembl.
GO; GO:0033092; P:positive regulation of immature T cell proliferation in thymus; IEA:Ensembl.
GO; GO:2000358; P:positive regulation of kidney smooth muscle cell differentiation; IEA:Ensembl.
GO; GO:2000729; P:positive regulation of mesenchymal cell proliferation involved in ureter development; IEA:Ensembl.
GO; GO:0061075; P:positive regulation of neural retina development; IMP:AgBase.
GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; IEA:Ensembl.
GO; GO:0045669; P:positive regulation of osteoblast differentiation; IDA:AgBase.
GO; GO:0042307; P:positive regulation of protein import into nucleus; IEA:Ensembl.
GO; GO:0061189; P:positive regulation of sclerotome development; IEA:Ensembl.
GO; GO:0014858; P:positive regulation of skeletal muscle cell proliferation; IEA:Ensembl.
GO; GO:0048643; P:positive regulation of skeletal muscle tissue development; IEA:Ensembl.
GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
GO; GO:0051155; P:positive regulation of striated muscle cell differentiation; IEA:Ensembl.
GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
GO; GO:2000063; P:positive regulation of ureter smooth muscle cell differentiation; IEA:Ensembl.
GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IEA:Ensembl.
GO; GO:0045059; P:positive thymic T cell selection; IEA:Ensembl.
GO; GO:0060516; P:primary prostatic bud elongation; IEA:Ensembl.
GO; GO:0060523; P:prostate epithelial cord elongation; IEA:Ensembl.
GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
GO; GO:0030166; P:proteoglycan biosynthetic process; IMP:AgBase.
GO; GO:0060785; P:regulation of apoptosis involved in tissue homeostasis; IMP:AgBase.
GO; GO:0060786; P:regulation of cell differentiation involved in tissue homeostasis; TAS:AgBase.
GO; GO:0010468; P:regulation of gene expression; IMP:AgBase.
GO; GO:0060782; P:regulation of mesenchymal cell proliferation involved in prostate gland development; IEA:Ensembl.
GO; GO:2000177; P:regulation of neural precursor cell proliferation; IMP:AgBase.
GO; GO:0042481; P:regulation of odontogenesis; IEA:Ensembl.
GO; GO:0060685; P:regulation of prostatic bud formation; IEA:Ensembl.
GO; GO:0001895; P:retina homeostasis; IMP:AgBase.
GO; GO:0003406; P:retinal pigment epithelium development; IMP:AgBase.
GO; GO:0060458; P:right lung development; IEA:Ensembl.
GO; GO:0060662; P:salivary gland cavitation; IEA:Ensembl.
GO; GO:0097264; P:self proteolysis; IDA:AgBase.
GO; GO:0043588; P:skin development; IEA:Ensembl.
GO; GO:0021938; P:smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; IEA:Ensembl.
GO; GO:0061053; P:somite development; IEA:Ensembl.
GO; GO:0021513; P:spinal cord dorsal/ventral patterning; IMP:AgBase.
GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
GO; GO:0014706; P:striated muscle tissue development; IEA:Ensembl.
GO; GO:0021978; P:telencephalon regionalization; IEA:Ensembl.
GO; GO:0021794; P:thalamus development; IEA:Ensembl.
GO; GO:0048538; P:thymus development; IEA:Ensembl.
GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
GO; GO:0009888; P:tissue development; IMP:AgBase.
GO; GO:0060439; P:trachea morphogenesis; IEA:Ensembl.
GO; GO:1905327; P:tracheoesophageal septum formation; IEA:Ensembl.
GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
Gene3D; 3.30.1380.10; -; 1.
InterPro; IPR001657; Hedgehog.
InterPro; IPR009045; Hedgehog_sig/DD-Pept_Zn-bd_dom.
InterPro; IPR000320; Hedgehog_signalling_dom.
InterPro; IPR001767; Hint_dom.
InterPro; IPR003586; Hint_dom_C.
InterPro; IPR003587; Hint_dom_N.
InterPro; IPR036844; Hint_dom_sf.
InterPro; IPR006141; Intein_N.
Pfam; PF01085; HH_signal; 1.
Pfam; PF01079; Hint; 1.
PIRSF; PIRSF009400; Peptidase_C46; 1.
PRINTS; PR00632; SONICHHOG.
SMART; SM00305; HintC; 1.
SMART; SM00306; HintN; 1.
SUPFAM; SSF51294; SSF51294; 1.
SUPFAM; SSF55166; SSF55166; 1.
PROSITE; PS50817; INTEIN_N_TER; 1.
3: Inferred from homology;
Autocatalytic cleavage {ECO:0000256|RuleBase:RU280812};
Calcium {ECO:0000256|PIRSR:PIRSR009400-2};
Cell membrane {ECO:0000256|RuleBase:RU280812};
Complete proteome {ECO:0000313|Proteomes:UP000000539};
Developmental protein {ECO:0000256|RuleBase:RU280812};
Hydrolase {ECO:0000256|RuleBase:RU280812};
Membrane {ECO:0000256|RuleBase:RU280812};
Metal-binding {ECO:0000256|PIRSR:PIRSR009400-2};
Protease {ECO:0000256|RuleBase:RU280812};
Reference proteome {ECO:0000313|Proteomes:UP000000539};
Secreted {ECO:0000256|RuleBase:RU280812};
Signal {ECO:0000256|RuleBase:RU280812, ECO:0000256|SAM:SignalP};
Zinc {ECO:0000256|PIRSR:PIRSR009400-2}.
SIGNAL 1 26 {ECO:0000256|SAM:SignalP}.
CHAIN 27 425 Hedgehog protein.
{ECO:0000256|SAM:SignalP}.
/FTId=PRO_5003268621.
DOMAIN 199 310 HintN. {ECO:0000259|SMART:SM00306}.
DOMAIN 313 358 HintC. {ECO:0000259|SMART:SM00305}.
METAL 92 92 Calcium 1.
{ECO:0000256|PIRSR:PIRSR009400-2}.
METAL 93 93 Calcium 1.
{ECO:0000256|PIRSR:PIRSR009400-2}.
METAL 93 93 Calcium 2.
{ECO:0000256|PIRSR:PIRSR009400-2}.
METAL 98 98 Calcium 1.
{ECO:0000256|PIRSR:PIRSR009400-2}.
METAL 128 128 Calcium 1; via carbonyl oxygen.
{ECO:0000256|PIRSR:PIRSR009400-2}.
METAL 129 129 Calcium 1.
{ECO:0000256|PIRSR:PIRSR009400-2}.
METAL 129 129 Calcium 2.
{ECO:0000256|PIRSR:PIRSR009400-2}.
METAL 132 132 Calcium 2.
{ECO:0000256|PIRSR:PIRSR009400-2}.
METAL 134 134 Calcium 2.
{ECO:0000256|PIRSR:PIRSR009400-2}.
METAL 143 143 Zinc. {ECO:0000256|PIRSR:PIRSR009400-2}.
METAL 150 150 Zinc. {ECO:0000256|PIRSR:PIRSR009400-2}.
METAL 185 185 Zinc. {ECO:0000256|PIRSR:PIRSR009400-2}.
SITE 200 201 Cleavage; by autolysis.
{ECO:0000256|PIRSR:PIRSR009400-1}.
SITE 246 246 Involved in cholesterol transfer.
{ECO:0000256|PIRSR:PIRSR009400-1}.
SITE 270 270 Involved in auto-cleavage.
{ECO:0000256|PIRSR:PIRSR009400-1}.
SITE 273 273 Essential for auto-cleavage.
{ECO:0000256|PIRSR:PIRSR009400-1}.
SEQUENCE 425 AA; 46488 MW; 144948CDC12FF8EC CRC64;
MDEMLLLTRI LLVGFICALL VSSGLTCGPG RGIGKRRHPK KLTPLAYKQF IPNVAEKTLG
ASGRYEGKIT RNSERFKELT PNYNPDIIFK DEENTGADRL MTQRCKDKLN ALAISVMNQW
PGVKLRVTEG WDEDGHHSEE SLHYEGRAVD ITTSDRDRSK YGMLARLAVE AGFDWVYYES
KAHIHCSVKA ENSVAAKSGG CFPGSATVHL EHGGTKLVKD LSPGDRVLAA DADGRLLYSD
FLTFLDREDS SRKLFYVIET RQPRARLLLT AAHLLFVAPQ HNQSEATGST SGQALFASNV
KPGQRVYVLG EGGQQLLPAS VHSVSLREEA SGAYAPLTAQ GTILINRVLA SCYAVIEEHS
WAHWAFAPFR LAQGLLAALC PDGAIPTAAT TTTGIHWYSR LLYRIGSWVL DGDALHPLGM
VAPAS


Related products :

Catalog number Product name Quantity
28-565 The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling. Its inactivation might lead to a deregulation of the tumor-promoting Hedgehog pathway in medulloblasto 0.1 mg
28-319 The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling. Its inactivation might lead to a deregulation of the tumor-promoting Hedgehog pathway in medulloblasto 0.1 mg
orb80580 Mouse Sonic HedgeHog protein Sonic Hedgehog Recombinant Mouse produced in E.coli is a single, non-glycosylated polypeptide chain containing 176 amino acids and having a molecular mass of 19.8 kDa. The 5
orb80579 Human Sonic HedgeHog His tag protein Sonic HedgeHog Recombinant Human produced in E.coli is a single, non-glycosylated polypeptide chain containing 183 amino acids and having a molecular mass of 20.7k 5
orb80100 Human Sonic HedgeHog protein Sonic HedgeHog Recombinant Human produced in E.coli is a single, non-glycosylated polypeptide chain containing 175 amino acids and having a molecular mass of 19,683 Dalton 5
60409 Gli Reporter – NIH3T3 Cell line (Hedgehog Pathway),The Gli Reporter – NIH3T3 Cell Line is designed for monitoring the activity of the hedgehog signaling pathway. The hedgehog pathway controls stem cel 500 reactions
100-153 Sonic Hedgehog Human Host: E. coli Sonic Hedgehog 25
GT15067-100 DHH (Desert Hedgehog Protein) 0.1 mg
GT15067-100 DHH (Desert Hedgehog Protein) 0.1 mg
MO15112-500 DHH (Desert Hedgehog Protein) 0.5 mg
MO15112-500 DHH (Desert Hedgehog Protein) 0.5 mg
ARP45230_T100 Indian hedgehog protein _ IHH 0.1 mg
EH1137 Desert hedgehog protein Elisa Kit 96T
PR15021-25 Indian hedgehog protein _ IHH (N_term) 25 µg
EH707 Indian hedgehog protein Elisa Kit 96T
E02H0058 Rat Hedgehog Interacting Protein ELISA 96T/kit
EH605 Sonic hedgehog protein Elisa Kit 96T
DM3552P Hedgehog Interacting Protein (HIP) (extracell. Dom) 0.1 mg
DM3552P Hedgehog Interacting Protein (HIP) (extracell. Dom) 0.1 mg
DM3552P Hedgehog Interacting Protein (HIP) (extracell. Dom) 0.1 mg
DM3579P Indian hedgehog protein _ IHH (N_term) 0.1 mg
EH3224 Hedgehog Interacting Protein Elisa Kit 96T
AP12312PU-N Indian hedgehog protein _ IHH (C_term) 0.1 mg
H2301 Sonic hedgehog protein (SHH), Rat, ELISA Kit 96T
CSB-EL021266RA Rat Sonic hedgehog protein(SHH) ELISA kit 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur