Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Hemagglutinin

 G3GIW1_9INFA            Unreviewed;       560 AA.
G3GIW1;
16-NOV-2011, integrated into UniProtKB/TrEMBL.
16-NOV-2011, sequence version 1.
05-JUL-2017, entry version 34.
RecName: Full=Hemagglutinin {ECO:0000256|SAAS:SAAS00070811};
Name=HA {ECO:0000313|EMBL:AEF10493.1};
Influenza A virus (A/Korean native chicken/Korea/K040110/2010(H9N2)).
Viruses; ssRNA viruses; ssRNA negative-strand viruses;
Orthomyxoviridae; Influenzavirus A.
NCBI_TaxID=1028674 {ECO:0000313|EMBL:AEF10493.1};
[1] {ECO:0000313|EMBL:AEF10493.1}
NUCLEOTIDE SEQUENCE.
STRAIN=A/Korean native chicken/Korea/K040110/2010
{ECO:0000313|EMBL:AEF10493.1};
Lee Y.N., Lee D.H., Park J.K., Lim T.H., Youn H.N., Yuk S.S.,
Lee J.B., Park S.Y., Choi I.S., Song C.S.;
"Isolation and characterization of a novel H9N2 influenza virus in
Korean native chicken farm.";
Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Binds to sialic acid-containing receptors on the cell
surface, bringing about the attachment of the virus particle to
the cell. This attachment induces virion internalization either
through clathrin-dependent endocytosis or through clathrin- and
caveolin-independent pathway. Plays a major role in the
determination of host range restriction and virulence. Class I
viral fusion protein. Responsible for penetration of the virus
into the cell cytoplasm by mediating the fusion of the membrane of
the endocytosed virus particle with the endosomal membrane. Low pH
in endosomes induces an irreversible conformational change in HA2,
releasing the fusion hydrophobic peptide. Several trimers are
required to form a competent fusion pore.
{ECO:0000256|SAAS:SAAS00842036}.
-!- FUNCTION: Binds to sialic acid-containing receptors on the cell
surface, bringing about the attachment of the virus particle to
the cell. This attachment induces virion internalization of about
two third of the virus particles through clathrin-dependent
endocytosis and about one third through a clathrin- and caveolin-
independent pathway. Plays a major role in the determination of
host range restriction and virulence. Class I viral fusion
protein. Responsible for penetration of the virus into the cell
cytoplasm by mediating the fusion of the membrane of the
endocytosed virus particle with the endosomal membrane. Low pH in
endosomes induces an irreversible conformational change in HA2,
releasing the fusion hydrophobic peptide. Several trimers are
required to form a competent fusion pore.
{ECO:0000256|RuleBase:RU003324}.
-!- SUBUNIT: Homotrimer of disulfide-linked HA1-HA2.
{ECO:0000256|RuleBase:RU003324, ECO:0000256|SAAS:SAAS00070616}.
-!- SUBCELLULAR LOCATION: Host apical cell membrane
{ECO:0000256|SAAS:SAAS00554492}; Single-pass type I membrane
protein {ECO:0000256|SAAS:SAAS00554492}.
-!- SUBCELLULAR LOCATION: Virion membrane
{ECO:0000256|SAAS:SAAS00810704}; Single-pass type I membrane
protein {ECO:0000256|SAAS:SAAS00810704}.
-!- SIMILARITY: Belongs to the influenza viruses hemagglutinin family.
{ECO:0000256|RuleBase:RU003324, ECO:0000256|SAAS:SAAS00554639}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; JF917103; AEF10493.1; -; Viral_cRNA.
GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
GO; GO:0075512; P:clathrin-dependent endocytosis of virus by host cell; IEA:UniProtKB-KW.
GO; GO:0039654; P:fusion of virus membrane with host endosome membrane; IEA:UniProtKB-KW.
GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:InterPro.
GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
Gene3D; 3.90.209.20; -; 1.
InterPro; IPR008980; Capsid_hemagglutn.
InterPro; IPR013828; Hemagglutn_HA1_a/b_dom.
InterPro; IPR000149; Hemagglutn_influenz_A.
InterPro; IPR001364; Hemagglutn_influenz_A/B.
Pfam; PF00509; Hemagglutinin; 1.
PRINTS; PR00330; HEMAGGLUTN1.
PRINTS; PR00329; HEMAGGLUTN12.
SUPFAM; SSF49818; SSF49818; 1.
3: Inferred from homology;
Clathrin- and caveolin-independent endocytosis of virus by host
{ECO:0000256|SAAS:SAAS00452788};
Clathrin-mediated endocytosis of virus by host
{ECO:0000256|SAAS:SAAS00453157}; Coiled coil {ECO:0000256|SAM:Coils};
Disulfide bond {ECO:0000256|SAAS:SAAS00810593};
Fusion of virus membrane with host endosomal membrane
{ECO:0000256|SAAS:SAAS00046943};
Fusion of virus membrane with host membrane
{ECO:0000256|SAAS:SAAS00046943};
Hemagglutinin {ECO:0000256|RuleBase:RU003324,
ECO:0000256|SAAS:SAAS00810689};
Host cell membrane {ECO:0000256|SAAS:SAAS00810598};
Host membrane {ECO:0000256|SAAS:SAAS00810598};
Host-virus interaction {ECO:0000256|SAAS:SAAS00441705};
Membrane {ECO:0000256|SAAS:SAAS00810598,
ECO:0000256|SAAS:SAAS00810736, ECO:0000256|SAM:Phobius};
Transmembrane {ECO:0000256|SAAS:SAAS00810736,
ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAAS:SAAS00810736,
ECO:0000256|SAM:Phobius};
Viral attachment to host cell {ECO:0000256|SAAS:SAAS00441705};
Viral envelope protein {ECO:0000256|RuleBase:RU003324,
ECO:0000256|SAAS:SAAS00810680};
Viral penetration into host cytoplasm {ECO:0000256|SAAS:SAAS00046943,
ECO:0000256|SAAS:SAAS00452788, ECO:0000256|SAAS:SAAS00453157};
Virion {ECO:0000256|RuleBase:RU003324, ECO:0000256|SAAS:SAAS00441705,
ECO:0000256|SAAS:SAAS00810680};
Virus endocytosis by host {ECO:0000256|SAAS:SAAS00452788,
ECO:0000256|SAAS:SAAS00453157};
Virus entry into host cell {ECO:0000256|SAAS:SAAS00046943,
ECO:0000256|SAAS:SAAS00441705, ECO:0000256|SAAS:SAAS00452788,
ECO:0000256|SAAS:SAAS00453157}.
TRANSMEM 525 548 Helical. {ECO:0000256|SAM:Phobius}.
COILED 394 428 {ECO:0000256|SAM:Coils}.
SEQUENCE 560 AA; 62557 MW; 9CABF72F10CC15E9 CRC64;
MEVIALIAIL VVTGTSNADK ICIGYQSTNS TETVDTLIET NVPVTHAKEL LHTEHNGMLC
ATNQGHPLIL DTCTVEGLVY GNPACDSLLG GKEWSYIVER SSAVHGMCYP GRVENLEELR
SFFSSARSYK RLLLFPDRTW NVTFTGTSKA CSGSFYRSMR WLTHKSNSYP IQDAQYTNDW
GKDILFVWGI HHPPTDTEQM SLYKKADTTT SITTEDINRT FKPVIGPRPI VNGQQGRIDY
YWSVLKPGQT LRIRSNGNLI APWYGHILSG ESHGRILKTD LNSGNCIVQC QTEKGGLNTT
LPFHNVSKYA FGNCPKYVGV KSLKLAVGLR NVPATSGRGL FGAISGFIEG GWPGLVAGWY
GFQHSNDQGV GMAADRESTQ TAVNKITSKV NNIIDKMNKQ YEIIDHEFNE IEARLNMINN
KIDDQIQDIW AYNAELLVLL ENQKTLDEHD ANVNNLYNKV KRALGSNAIE DGKGCFELYH
KCDDQCMETI RNGTYDMVKY KEESKLERQK IEGVKLESEG TYKILTIYST VASSLMLAIG
FAAFMFWVMS NGSCRCNICI


Related products :

Catalog number Product name Quantity
'AP30771PU-N Seasonal H1N1 Hemagglutinin (Hemagglutinin) IgG antibody Ab host: Rabbit 0.1 mg
'AP30772PU-N Seasonal H1N1 Hemagglutinin (Hemagglutinin) IgG antibody Ab host: Rabbit 0.1 mg
'AP30770PU-N Seasonal H1N1 Hemagglutinin (Hemagglutinin) IgG antibody Ab host: Rabbit 0.1 mg
orb81770 Measles Virus Hemagglutinin Mosaic (1-30,115-150,379-410) protein The E.coli derived recombinant protein contains the large hemagglutinin immunodominant regions 1-30, 115-150 and 379-410 amino acids. 100
orb82556 Influenza A H5N1 Hemagglutinin protein Influenza A H5N1 (Avian) Hemagglutinin (Middle Region) is an infectious disease antigen_toxin. For research use only. 50
orb82554 Influenza A H5N1 Hemagglutinin protein Influenza A H5N1 (Avian) Hemagglutinin (Middle Region) is an infectious disease antigen_toxin. For research use only. 50
orb82553 Influenza A H5N1 Hemagglutinin protein Influenza A H5N1 (Avian) Hemagglutinin (Middle Region) is an infectious disease antigen_toxin. For research use only. 50
orb82548 Influenza A H5N1 Hemagglutinin protein Influenza A H5N1 (Avian) Hemagglutinin, N-terminal is an infectious disease antigen_toxin. For research use only. 50
orb82555 Influenza A H5N1 Hemagglutinin protein Influenza A H5N1 (Avian) Hemagglutinin, N-terminal is an infectious disease antigen_toxin. For research use only. 50
5317-0170 MOUSE ANTI INFLUENZA B HEMAGGLUTININ, Product Type Monoclonal Antibody, Specificity INFLUENZA B HEMAGGLUTININ, Target Species Viral, Host Mouse, Format Purified, Isotypes IgG, Applications C, E 0.2 mg
SCH-5317-0170 MOUSE ANTI INFLUENZA B HEMAGGLUTININ, Product Type Monoclonal Antibody, Specificity INFLUENZA B HEMAGGLUTININ, Target Species Viral, Host Mouse, Format Purified, Isotypes IgG, Applications C, E 0.2 mg
SCH-OBT1646 CHICKEN ANTI INFLUENZA HEMAGGLUTININ, Product Type Polyclonal Antibody, Specificity INFLUENZA HEMAGGLUTININ, Target Species Viral, Host Chicken, Format Purified, Isotypes Polyclonal IgG, Applica 0.1 mg
OBT1646 CHICKEN ANTI INFLUENZA HEMAGGLUTININ, Product Type Polyclonal Antibody, Specificity INFLUENZA HEMAGGLUTININ, Target Species Viral, Host Chicken, Format Purified, Isotypes Polyclonal IgG, Applica 0.1 mg
3924BP-50 Influenza A Virus Hemagglutinin (HA) Blocking Peptide target: Influenza A Virus Hemagglutinin (HA) 50 μg
5315-2907 MOUSE ANTI INFLUENZA A H1N1 HEMAGGLUTININ, Product Type Monoclonal Antibody, Specificity INFLUENZA A H1N1 HEMAGGLUTININ, Target Species Viral, Host Mouse, Format Purified, Isotypes IgG1, Applica 0.2 mg
SCH-5315-2907 MOUSE ANTI INFLUENZA A H1N1 HEMAGGLUTININ, Product Type Monoclonal Antibody, Specificity INFLUENZA A H1N1 HEMAGGLUTININ, Target Species Viral, Host Mouse, Format Purified, Isotypes IgG1, Applica 0.2 mg
orb71664 Vial Hemagglutinin (48-68) peptide This is Vial Hemagglutinin (48-68) peptide. For research use only. 1 mg
PC-255 HA Hemagglutinin (YPYDVPDYA) 0.1 mg
PC-259 Hemagglutinin (YPYDVPDYA) 0.1 mg
170 Filamentous Hemagglutinin (FHA) 50µg
PC-259 Hemagglutinin (YPYDVPDYA) 0.1 mg
PC-255 HA Hemagglutinin (YPYDVPDYA) 0.1 mg
170 Filamentous Hemagglutinin (FHA) 50 µg
E02H0215 Rat hemagglutinin 96 Tests/kit
PC-256 HA Hemagglutinin (YPYDVPDYA) 1 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur