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Heterogeneous nuclear ribonucleoprotein at 27C, isoform D (Heterogeneous nuclear ribonucleoprotein at 27C, isoform E) (Heterogeneous nuclear ribonucleoprotein at 27C, isoform F) (Heterogeneous nuclear ribonucleoprotein at 27C, isoform G) (Heterogeneous nuclear ribonucleoprotein at 27C, isoform H)

 E1JHA4_DROME            Unreviewed;       421 AA.
E1JHA4;
30-NOV-2010, integrated into UniProtKB/TrEMBL.
30-NOV-2010, sequence version 1.
22-NOV-2017, entry version 68.
SubName: Full=Heterogeneous nuclear ribonucleoprotein at 27C, isoform D {ECO:0000313|EMBL:ACZ94188.1};
SubName: Full=Heterogeneous nuclear ribonucleoprotein at 27C, isoform E {ECO:0000313|EMBL:ACZ94189.1};
SubName: Full=Heterogeneous nuclear ribonucleoprotein at 27C, isoform F {ECO:0000313|EMBL:AFH03591.1};
SubName: Full=Heterogeneous nuclear ribonucleoprotein at 27C, isoform G {ECO:0000313|EMBL:AFH03592.1};
SubName: Full=Heterogeneous nuclear ribonucleoprotein at 27C, isoform H {ECO:0000313|EMBL:AFH03593.1};
Name=Hrb27C {ECO:0000313|EMBL:ACZ94188.1,
ECO:0000313|FlyBase:FBgn0004838};
Synonyms=10280 {ECO:0000313|EMBL:ACZ94188.1},
Dmel\CG10377 {ECO:0000313|EMBL:ACZ94188.1},
hnRNP27C {ECO:0000313|EMBL:ACZ94188.1},
hnRNP48 {ECO:0000313|EMBL:ACZ94188.1},
hrb27 {ECO:0000313|EMBL:ACZ94188.1},
Hrb27-C {ECO:0000313|EMBL:ACZ94188.1},
HRB27C {ECO:0000313|EMBL:ACZ94188.1},
Hrb27c {ECO:0000313|EMBL:ACZ94188.1},
hrb27C {ECO:0000313|EMBL:ACZ94188.1},
hrb27c {ECO:0000313|EMBL:ACZ94188.1},
Hrb48 {ECO:0000313|EMBL:ACZ94188.1},
HRP48 {ECO:0000313|EMBL:ACZ94188.1},
Hrp48 {ECO:0000313|EMBL:ACZ94188.1},
hrp48 {ECO:0000313|EMBL:ACZ94188.1},
l(2)02647 {ECO:0000313|EMBL:ACZ94188.1},
l(2)10280 {ECO:0000313|EMBL:ACZ94188.1},
l(2)2647 {ECO:0000313|EMBL:ACZ94188.1},
linha {ECO:0000313|EMBL:ACZ94188.1},
Ov5 {ECO:0000313|EMBL:ACZ94188.1}, p50 {ECO:0000313|EMBL:ACZ94188.1},
Rbp7 {ECO:0000313|EMBL:ACZ94188.1},
RRM7 {ECO:0000313|EMBL:ACZ94188.1},
rrm7 {ECO:0000313|EMBL:ACZ94188.1};
ORFNames=CG10377 {ECO:0000313|EMBL:ACZ94188.1,
ECO:0000313|FlyBase:FBgn0004838},
Dmel_CG10377 {ECO:0000313|EMBL:ACZ94188.1};
Drosophila melanogaster (Fruit fly).
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
Ephydroidea; Drosophilidae; Drosophila; Sophophora.
NCBI_TaxID=7227 {ECO:0000313|EMBL:ACZ94188.1, ECO:0000313|Proteomes:UP000000803};
[1] {ECO:0000313|EMBL:ACZ94188.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=10731132; DOI=10.1126/science.287.5461.2185;
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X.,
Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D.,
Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L.,
Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D.,
Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M.,
Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S.,
Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P.,
Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I.,
Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P.,
de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M.,
Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P.,
Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W.,
Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K.,
Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J.,
Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C.,
Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A.,
Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z.,
Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X.,
Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D.,
Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A.,
Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L.,
Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M.,
Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G.,
Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H.,
Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.,
Spier E., Spradling A.C., Stapleton M., Strong R., Sun E.,
Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X.,
Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J.,
Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J.,
Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L.,
Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O.,
Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
"The genome sequence of Drosophila melanogaster.";
Science 287:2185-2195(2000).
[2] {ECO:0000313|EMBL:ACZ94188.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=12537568;
Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
"Finishing a whole-genome shotgun: release 3 of the Drosophila
melanogaster euchromatic genome sequence.";
Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
[3] {ECO:0000313|EMBL:ACZ94188.1, ECO:0000313|Proteomes:UP000000803}
GENOME REANNOTATION.
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P.,
Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A.,
Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q.,
Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M.,
Lewis S.E.;
"Annotation of the Drosophila melanogaster euchromatic genome: a
systematic review.";
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
[4] {ECO:0000313|EMBL:ACZ94188.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=12537573;
Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M.,
Ashburner M., Celniker S.E.;
"The transposable elements of the Drosophila melanogaster euchromatin:
a genomics perspective.";
Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002).
[5] {ECO:0000313|EMBL:ACZ94188.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=12537574;
Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
Karpen G.H.;
"Heterochromatic sequences in a Drosophila whole-genome shotgun
assembly.";
Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
[6] {ECO:0000313|EMBL:ACZ94188.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
Ashburner M., Anxolabehere D.;
"Combined evidence annotation of transposable elements in genome
sequences.";
PLoS Comput. Biol. 1:166-175(2005).
[7] {ECO:0000313|EMBL:ACZ94188.1}
NUCLEOTIDE SEQUENCE.
Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,
Svirskas R., Rubin G.;
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
[8] {ECO:0000313|EMBL:ACZ94188.1}
NUCLEOTIDE SEQUENCE.
Berkeley Drosophila Genome Project;
Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,
Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,
Yu C., Rubin G.;
"Drosophila melanogaster release 4 sequence.";
Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
[9] {ECO:0000313|EMBL:ACZ94188.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=17569856; DOI=10.1126/science.1139815;
Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
"The Release 5.1 annotation of Drosophila melanogaster
heterochromatin.";
Science 316:1586-1591(2007).
[10] {ECO:0000313|EMBL:ACZ94188.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=17569867; DOI=10.1126/science.1139816;
Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
Dimitri P., Karpen G.H., Celniker S.E.;
"Sequence finishing and mapping of Drosophila melanogaster
heterochromatin.";
Science 316:1625-1628(2007).
[11] {ECO:0000313|EMBL:ACZ94188.1}
NUCLEOTIDE SEQUENCE.
FlyBase;
Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AE014134; ACZ94188.1; -; Genomic_DNA.
EMBL; AE014134; ACZ94189.1; -; Genomic_DNA.
EMBL; AE014134; AFH03591.1; -; Genomic_DNA.
EMBL; AE014134; AFH03592.1; -; Genomic_DNA.
EMBL; AE014134; AFH03593.1; -; Genomic_DNA.
RefSeq; NP_001162897.1; NM_001169426.2.
RefSeq; NP_001162898.1; NM_001169427.2.
RefSeq; NP_001245917.1; NM_001258988.2.
RefSeq; NP_001245918.1; NM_001258989.2.
RefSeq; NP_001245919.1; NM_001258990.2.
RefSeq; NP_476869.1; NM_057521.6.
RefSeq; NP_723228.1; NM_164720.4.
RefSeq; NP_723229.1; NM_164721.3.
UniGene; Dm.1997; -.
EnsemblMetazoa; FBtr0079346; FBpp0078974; FBgn0004838.
EnsemblMetazoa; FBtr0079347; FBpp0078975; FBgn0004838.
EnsemblMetazoa; FBtr0079348; FBpp0078976; FBgn0004838.
EnsemblMetazoa; FBtr0301403; FBpp0290617; FBgn0004838.
EnsemblMetazoa; FBtr0301404; FBpp0290618; FBgn0004838.
EnsemblMetazoa; FBtr0307030; FBpp0297873; FBgn0004838.
EnsemblMetazoa; FBtr0307031; FBpp0297874; FBgn0004838.
EnsemblMetazoa; FBtr0307032; FBpp0297875; FBgn0004838.
GeneID; 33968; -.
KEGG; dme:Dmel_CG10377; -.
CTD; 33968; -.
FlyBase; FBgn0004838; Hrb27C.
eggNOG; KOG4205; Eukaryota.
eggNOG; ENOG410YA8Z; LUCA.
KO; K14411; -.
OMA; ALENGPH; -.
OrthoDB; EOG091G1CPI; -.
ChiTaRS; Hrb27C; fly.
GenomeRNAi; 33968; -.
Proteomes; UP000000803; Chromosome 2L.
Bgee; FBgn0004838; -.
GO; GO:0030529; C:intracellular ribonucleoprotein complex; IEA:UniProtKB-KW.
GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-KW.
GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
CDD; cd12574; RRM1_DAZAP1; 1.
CDD; cd12327; RRM2_DAZAP1; 1.
InterPro; IPR034134; DAZAP1_RRM1.
InterPro; IPR034131; DAZAP1_RRM2.
InterPro; IPR035979; RBD_domain_sf.
InterPro; IPR000504; RRM_dom.
Pfam; PF00076; RRM_1; 2.
SMART; SM00360; RRM; 2.
SUPFAM; SSF54928; SSF54928; 2.
PROSITE; PS50102; RRM; 2.
1: Evidence at protein level;
Complete proteome {ECO:0000313|Proteomes:UP000000803};
Proteomics identification {ECO:0000213|PeptideAtlas:E1JHA4};
Reference proteome {ECO:0000313|Proteomes:UP000000803};
Ribonucleoprotein {ECO:0000313|EMBL:ACZ94188.1};
RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
Viral nucleoprotein {ECO:0000313|EMBL:ACZ94188.1};
Virion {ECO:0000313|EMBL:ACZ94188.1}.
DOMAIN 7 88 RRM. {ECO:0000259|PROSITE:PS50102}.
DOMAIN 96 173 RRM. {ECO:0000259|PROSITE:PS50102}.
SEQUENCE 421 AA; 44770 MW; D59DD2A647CE23F5 CRC64;
MEEDERGKLF VGGLSWETTQ ENLSRYFCRF GDIIDCVVMK NNESGRSRGF GFVTFADPTN
VNHVLQNGPH TLDGRTIDPK PCNPRTLQKP KKGGGYKVFL GGLPSNVTET DLRTFFNRYG
KVTEVVIMYD QEKKKSRGFG FLSFEEESSV EHVTNERYIN LNGKQVEIKK AEPRDGSGGQ
NSNNSTVGGA YGKLGNECSH WGPHHAPINM MQGQNGQMGG PPLNMPIGAP NMMPGYQGWG
TSPQQQQYGY GNSGPGSYQG WGAPPGPQGP PPQWSNYAGP QQTQGYGGYD MYNSTSTGAP
SGPSGGGSWN SWNMPPNSAG PTGAPGAGAG TATDMYSRAQ AWATGGPSTT GPVGGMPRTG
PGNSASKSGS EYDYGGYGSG YDYDYSNYVK QEGASNYGAG PRSAYGNDSS TQPPYATSQA
V


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