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Histone deacetylase 11 (Histone deacetylase 11 isoform 1)

 F7D6G8_MACMU            Unreviewed;       347 AA.
F7D6G8; F7HB89; I2CXN6;
27-JUL-2011, integrated into UniProtKB/TrEMBL.
30-NOV-2016, sequence version 2.
22-NOV-2017, entry version 47.
SubName: Full=Histone deacetylase 11 {ECO:0000313|Ensembl:ENSMMUP00000001824};
SubName: Full=Histone deacetylase 11 isoform 1 {ECO:0000313|EMBL:AFJ71721.1};
Name=HDAC11 {ECO:0000313|EMBL:AFJ71721.1,
ECO:0000313|Ensembl:ENSMMUP00000001824};
Macaca mulatta (Rhesus macaque).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000001824, ECO:0000313|Proteomes:UP000006718};
[1] {ECO:0000313|Ensembl:ENSMMUP00000001824, ECO:0000313|Proteomes:UP000006718}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000001824,
ECO:0000313|Proteomes:UP000006718};
PubMed=17431167; DOI=10.1126/science.1139247;
Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C.,
Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W.,
Hardison R.C., Makova K.D., Miller W., Milosavljevic A., Palermo R.E.,
Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y.,
Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T.,
Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J.,
Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A.,
Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M.,
Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D.,
Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J.,
Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E.,
Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S.,
Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X.,
Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E.,
Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M.,
Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M.,
Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y.,
Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J.,
Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A.,
Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B.,
Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S.,
Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V.,
Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A.,
Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C.,
Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P.,
Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E.,
Zwieg A.S.;
"Evolutionary and biomedical insights from the rhesus macaque
genome.";
Science 316:222-234(2007).
[2] {ECO:0000313|Ensembl:ENSMMUP00000001824}
IDENTIFICATION.
STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000001824};
Ensembl;
Submitted (JUL-2011) to UniProtKB.
[3] {ECO:0000313|EMBL:AFJ71721.1}
NUCLEOTIDE SEQUENCE.
TISSUE=Orbital {ECO:0000313|EMBL:AFJ71721.1};
PubMed=25319552; DOI=10.1186/1745-6150-9-20;
Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X.,
Pandey S., Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P.,
Tharp G.K., Marcais G., Roberts M., Ferguson B., Fox H.S.,
Treangen T., Salzberg S.L., Yorke J.A., Norgren R.B.Jr.;
"A new rhesus macaque assembly and annotation for next-generation
sequencing analyses.";
Biol. Direct 9:20-20(2014).
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EMBL; JSUE03023159; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; JV636381; AFJ71721.1; -; mRNA.
RefSeq; NP_001252584.1; NM_001265655.1.
UniGene; Mmu.23629; -.
STRING; 9544.ENSMMUP00000001824; -.
Ensembl; ENSMMUT00000001935; ENSMMUP00000001824; ENSMMUG00000001369.
Ensembl; ENSMMUT00000046773; ENSMMUP00000039801; ENSMMUG00000001369.
GeneID; 693537; -.
KEGG; mcc:693537; -.
CTD; 79885; -.
eggNOG; KOG1344; Eukaryota.
eggNOG; COG0123; LUCA.
GeneTree; ENSGT00900000140987; -.
InParanoid; F7D6G8; -.
KO; K11418; -.
OrthoDB; EOG091G0EQP; -.
TreeFam; TF106176; -.
Proteomes; UP000006718; Chromosome 2.
Bgee; ENSMMUG00000001369; -.
ExpressionAtlas; F7D6G8; baseline.
GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
GO; GO:0000118; C:histone deacetylase complex; IEA:Ensembl.
GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
GO; GO:0004407; F:histone deacetylase activity; IEA:Ensembl.
Gene3D; 3.40.800.20; -; 1.
InterPro; IPR000286; His_deacetylse.
InterPro; IPR023801; His_deacetylse_dom.
InterPro; IPR037138; His_deacetylse_dom_sf.
InterPro; IPR023696; Ureohydrolase_dom_sf.
Pfam; PF00850; Hist_deacetyl; 1.
PRINTS; PR01270; HDASUPER.
SUPFAM; SSF52768; SSF52768; 1.
2: Evidence at transcript level;
Complete proteome {ECO:0000313|Proteomes:UP000006718};
Hydrolase {ECO:0000256|SAAS:SAAS00870288};
Reference proteome {ECO:0000313|Proteomes:UP000006718}.
DOMAIN 35 316 Hist_deacetyl.
{ECO:0000259|Pfam:PF00850}.
SEQUENCE 347 AA; 39179 MW; 4C3DADC2D8770B0D CRC64;
MLHTTQLYQH VPETRWPIVY SPRYNITFMG LEKLHPFDAG KWGKVINFLK EEKLLSDSML
VEAREASEED LLVVHTRRYL NELKWSFAVA TITEIPPVIF LPNFLVQRKV LRPLRTQTGG
TIMAGKLAVE RGWAINVGGG FHHCSSDRGG GFCAYADITL AIKFLFERVE GISRATIIDL
DAHQGNGHER DFMDDKRVYI MDVYNRHIYP GDRFAKQAIR RKVELEWGTE DDEYLDKVER
NIEKSLQEHL PDVVVYNAGT DILEGDRLGG LSISPAGIVK RDELVFRMVR GRHVPILMVT
SGGYQKRTAR IIADSILNLF GLGLIGPESP SISAQNSDTP LLPPAVP


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