Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Histone-lysine N-methyltransferase EZ3 (EC 2.1.1.43) (Enhancer of zeste protein 3)

 EZ3_MAIZE               Reviewed;         895 AA.
Q8S4P4;
19-JUL-2003, integrated into UniProtKB/Swiss-Prot.
01-JUN-2002, sequence version 1.
20-DEC-2017, entry version 86.
RecName: Full=Histone-lysine N-methyltransferase EZ3;
EC=2.1.1.43;
AltName: Full=Enhancer of zeste protein 3;
Name=EZ3; Synonyms=MEZ3;
Zea mays (Maize).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae;
PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae;
Zea.
NCBI_TaxID=4577;
[1]
NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
TISSUE=Seed;
PubMed=11950982; DOI=10.1104/pp.010742;
Springer N.M., Danilevskaya O.N., Hermon P., Helentjaris T.G.,
Phillips R.L., Kaeppler H.F., Kaeppler S.M.;
"Sequence relationships, conserved domains, and expression patterns
for maize homologs of the Polycomb group genes E(z), esc, and E(Pc).";
Plant Physiol. 128:1332-1345(2002).
-!- FUNCTION: Polycomb group (PcG) protein. Catalytic subunit of some
PcG multiprotein complex, which methylates 'Lys-27' of histone H3,
leading to transcriptional repression of the affected target
genes. PcG proteins are not required to initiate repression, but
to maintain it during later stages of development (By similarity).
{ECO:0000250}.
-!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + L-lysine-[histone] =
S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
{ECO:0000255|PROSITE-ProRule:PRU00909}.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
-!- TISSUE SPECIFICITY: Widely expressed.
{ECO:0000269|PubMed:11950982}.
-!- SIMILARITY: Belongs to the class V-like SAM-binding
methyltransferase superfamily. Histone-lysine methyltransferase
family. EZ subfamily. {ECO:0000255|PROSITE-ProRule:PRU00909}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AF443598; AAM13422.1; -; mRNA.
RefSeq; NP_001105079.1; NM_001111609.1.
UniGene; Zm.10341; -.
ProteinModelPortal; Q8S4P4; -.
SMR; Q8S4P4; -.
STRING; 4577.GRMZM2G043484_P02; -.
PaxDb; Q8S4P4; -.
GeneID; 541955; -.
KEGG; zma:541955; -.
MaizeGDB; 754846; -.
eggNOG; KOG1079; Eukaryota.
eggNOG; COG2940; LUCA.
HOGENOM; HOG000083511; -.
KO; K11430; -.
Proteomes; UP000007305; Unplaced.
ExpressionAtlas; Q8S4P4; baseline and differential.
GO; GO:0031519; C:PcG protein complex; IEA:InterPro.
GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
CDD; cd00167; SANT; 1.
InterPro; IPR026489; CXC_dom.
InterPro; IPR025778; Hist-Lys_N-MeTrfase_EZ.
InterPro; IPR001005; SANT/Myb.
InterPro; IPR001214; SET_dom.
InterPro; IPR033467; Tesmin/TSO1-like_CXC.
PANTHER; PTHR22884:SF237; PTHR22884:SF237; 1.
Pfam; PF00856; SET; 1.
SMART; SM01114; CXC; 1.
SMART; SM00317; SET; 1.
PROSITE; PS51633; CXC; 1.
PROSITE; PS51576; SAM_MT43_EZ; 1.
PROSITE; PS50280; SET; 1.
2: Evidence at transcript level;
Complete proteome; Methyltransferase; Nucleus; Reference proteome;
Repressor; S-adenosyl-L-methionine; Transcription;
Transcription regulation; Transferase.
CHAIN 1 895 Histone-lysine N-methyltransferase EZ3.
/FTId=PRO_0000214000.
DOMAIN 528 578 SANT.
DOMAIN 628 732 CXC. {ECO:0000255|PROSITE-
ProRule:PRU00970}.
DOMAIN 747 862 SET. {ECO:0000255|PROSITE-
ProRule:PRU00190}.
COMPBIAS 75 78 Poly-Ala.
COMPBIAS 650 719 Cys-rich.
SEQUENCE 895 AA; 100393 MW; 2659DCF992A08919 CRC64;
MASSSKASDS SSQRSKRSDQ GTGREAAPAS VVPIHGNLTQ LIRQIKSRRL LYIKEKLEAN
RKTLQRHSCS LFDVAAAAEV ASRGSDGGNA LSQRAAEGQF RLAGSDLAHG IGERDVVYMQ
EENLASGTLV LSSSGAAAQR TVVRFVKLPL VERIPPYTTW IFLDKNQRMA DDQSVVGRRR
IYYDPVGNEA LICSDSDEEI PEPEEEKHFF TEGEDQLIWR ATQEHGLNRE VVNVLCQFID
STPSEIEERS EVLFEKNEKN SGSSDKIERQ LSLDKTMDAV LDSFDNLFCR RCLVFDCRLH
GCSQNLVFPT EKQPYSFEPD ENKKPCGRQC YLRWRGGFQE IHDVGLSGCA TYNMESGTVS
HKVDVSIMSE SEDSNREKGN IRSMTLVGTS GSKIISSVSA EESTTPPSAD TSETENASSD
MPPSSLRKYK ISKRGPRYRE RSPGKRQKVF TSDISFASNI LNKLSIPEIR DTRLESREPG
GDKLQILDES TKKTSSKDIC GESPITTTEN MGIESKKVSS TKNFLEHTLS CWSALERDLY
LKGIEIFGKN SCLIARNLLS GMKTCMEVAN YMYNNGAAMA KRPLLNKSIS GDFAETEQDY
MEQDMVARTR IYRRRGRNRK LKYTWKSAGH PTVRKRIGDG KQWYTQYNPC VCQQMCGKDC
PCVENGTCCE KYCGCSKSCK NKFRGCHCAK SQCRSRQCPC FAASRECDPD VCRNCWVSCG
DGSLGEPPAR GDGYQCGNMK LLLKQQQRIL LGRSDVAGWG AFIKNPVNKN DYLGEYTGEL
ISHKEADKRG KIYDRANSSF LFDLNDQYVL DAYRKGDKLK FANHSSNPNC YAKVMLVAGD
HRVGIYAKEH IEASEELFYD YRYGPDQAPA WARRPEGSKK DEASVSHHRA HKVAR


Related products :

Catalog number Product name Quantity
EIAAB13541 Enhancer of zeste homolog 2,ENX-1,EZH2,Histone-lysine N-methyltransferase EZH2,Homo sapiens,Human,KMT6,Lysine N-methyltransferase 6
EIAAB13537 Bos taurus,Bovine,Enhancer of zeste homolog 1,EZH1,Histone-lysine N-methyltransferase EZH1
EIAAB13538 Enhancer of zeste homolog 1,Enx2,ENX-2,Ezh1,Histone-lysine N-methyltransferase EZH1,Mouse,Mus musculus
EIAAB13540 Enhancer of zeste homolog 2,ENX-1,Enx1h,Ezh2,Histone-lysine N-methyltransferase EZH2,Mouse,Mus musculus
EIAAB13539 Enhancer of zeste homolog 1,ENX-2,EZH1,Histone-lysine N-methyltransferase EZH1,Homo sapiens,Human,KIAA0388
EIAAB11717 DOT1L,DOT1-like protein,H3-K79-HMTase,Histone H3-K79 methyltransferase,Histone-lysine N-methyltransferase, H3 lysine-79 specific,Homo sapiens,Human,KIAA1814,KMT4,Lysine N-methyltransferase 4
EIAAB12652 Ehmt1,Euchromatic histone-lysine N-methyltransferase 1,Euhmtase1,Eu-HMTase1,G9a-like protein 1,GLP,Glp,GLP1,Histone-lysine N-methyltransferase EHMT1,Kmt1d,Lysine N-methyltransferase 1D,Mouse,Mus muscu
EIAAB37955 ERG-associated protein with SET domain,ESET,H3-K9-HMTase 4,Histone H3-K9 methyltransferase 4,Histone-lysine N-methyltransferase SETDB1,Homo sapiens,Human,KIAA0067,KMT1E,Lysine N-methyltransferase 1E,S
EIAAB37951 Histone-lysine N-methyltransferase SETD1A,Homo sapiens,hSET1A,Human,KIAA0339,KMT2F,Lysine N-methyltransferase 2F,SET domain-containing protein 1A,SET1,Set1_Ash2 histone methyltransferase complex subun
EIAAB12653 EHMT1,Euchromatic histone-lysine N-methyltransferase 1,EUHMTASE1,Eu-HMTase1,G9a-like protein 1,GLP,GLP,GLP1,H3-K9-HMTase 5,Histone H3-K9 methyltransferase 5,Histone-lysine N-methyltransferase EHMT1,Ho
EIAAB40615 H3-K9-HMTase 1,Histone H3-K9 methyltransferase 1,Histone-lysine N-methyltransferase SUV39H1,Homo sapiens,Human,KMT1A,Lysine N-methyltransferase 1A,Position-effect variegation 3-9 homolog,Su(var)3-9 ho
EIAAB40618 H3-K9-HMTase 2,Histone H3-K9 methyltransferase 2,Histone-lysine N-methyltransferase SUV39H2,Homo sapiens,Human,KMT1B,Lysine N-methyltransferase 1B,Su(var)3-9 homolog 2,Suppressor of variegation 3-9 ho
EIAAB37975 H3-K4-HMTase SETD7,Histone H3-K4 methyltransferase SETD7,Histone-lysine N-methyltransferase SETD7,Homo sapiens,Human,KIAA1717,KMT7,Lysine N-methyltransferase 7,SET domain-containing protein 7,SET7,SET
EIAAB37977 H4-K20-HMTase SETD8,Histone-lysine N-methyltransferase SETD8,Homo sapiens,Human,KMT5A,Lysine N-methyltransferase 5A,N-lysine methyltransferase SETD8,PR_SET domain-containing protein 07,PR_SET07,PRSET7
EIAAB12654 Bat8,Ehmt2,Euchromatic histone-lysine N-methyltransferase 2,G9a,H3-K9-HMTase 3,Histone H3-K9 methyltransferase 3,Histone-lysine N-methyltransferase EHMT2,HLA-B-associated transcript 8,Mouse,Mus muscul
EIAAB12655 BAT8,C6orf30,EHMT2,Euchromatic histone-lysine N-methyltransferase 2,G9A,H3-K9-HMTase 3,Histone H3-K9 methyltransferase 3,Histone-lysine N-methyltransferase EHMT2,HLA-B-associated transcript 8,Homo sap
EIAAB38899 Histone methyltransferase SMYD2,Homo sapiens,HSKM-B,Human,KMT3C,Lysine N-methyltransferase 3C,N-lysine methyltransferase SMYD2,SET and MYND domain-containing protein 2,SMYD2
EIAAB27934 DC28,Histone-lysine N-methyltransferase NSD3,Homo sapiens,Human,NSD3,Nuclear SET domain-containing protein 3,Protein whistle,WHSC1L1,WHSC1-like 1 isoform 9 with methyltransferase activity to lysine,WH
EIAAB37958 C13orf4,Chronic lymphocytic leukemia deletion region gene 8 protein,CLLD8,Histone-lysine N-methyltransferase SETDB2,Homo sapiens,Human,KMT1F,Lysine N-methyltransferase 1F,SET domain bifurcated 2,SETDB
EIAAB37954 Histone-lysine N-methyltransferase SETD1B,Homo sapiens,hSET1B,Human,KIAA1076,KMT2G,Lysine N-methyltransferase 2G,SET domain-containing protein 1B,SET1B,SETD1B
18-003-42222 Histone-lysine N-methyltransferase. H3 lysine-9 specific 1 - EC 2.1.1.43; Histone H3-K9 methyltransferase 1; H3-K9-HMTase 1; Suppressor of variegation 3-9 homolog 1; Su(var)3-9 homolog 1 Polyclonal 0.1 mg Protein A
EIAAB24941 HALR,Histone-lysine N-methyltransferase MLL3,Homo sapiens,Homologous to ALR protein,Human,KIAA1506,KMT2C,KMT2C,Lysine N-methyltransferase 2C,MLL3,Myeloid_lymphoid or mixed-lineage leukemia protein 3
EIAAB24940 ALL1-related protein,ALR,Histone-lysine N-methyltransferase MLL2,Homo sapiens,Human,KMT2B,KMT2B,Lysine N-methyltransferase 2B,MLL2,Myeloid_lymphoid or mixed-lineage leukemia protein 2
EIAAB24938 ALL1,ALL-1,CXXC7,CXXC-type zinc finger protein 7,Histone-lysine N-methyltransferase MLL,Homo sapiens,HRX,HTRX,Human,KMT2A,KMT2A,Lysine N-methyltransferase 2A,MLL,MLL1,Trithorax-like protein,TRX1,Zinc
EIAAB24945 Histone-lysine N-methyltransferase MLL5,Homo sapiens,Human,KMT2E,KMT2E,Lysine N-methyltransferase 2E,MLL5,Myeloid_lymphoid or mixed-lineage leukemia protein 5


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur