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Homeobox A4

 F6VMM4_XENTR            Unreviewed;       248 AA.
F6VMM4;
27-JUL-2011, integrated into UniProtKB/TrEMBL.
27-JUL-2011, sequence version 1.
22-NOV-2017, entry version 46.
SubName: Full=Homeobox A4 {ECO:0000313|Ensembl:ENSXETP00000057392};
Name=hoxa4 {ECO:0000313|Ensembl:ENSXETP00000057392};
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
Silurana.
NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000057392, ECO:0000313|Proteomes:UP000008143};
[1] {ECO:0000313|Ensembl:ENSXETP00000057392}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000057392};
PubMed=20431018; DOI=10.1126/science.1183670;
Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L.,
Blitz I.L., Blumberg B., Dichmann D.S., Dubchak I., Amaya E.,
Detter J.C., Fletcher R., Gerhard D.S., Goodstein D., Graves T.,
Grigoriev I.V., Grimwood J., Kawashima T., Lindquist E., Lucas S.M.,
Mead P.E., Mitros T., Ogino H., Ohta Y., Poliakov A.V., Pollet N.,
Robert J., Salamov A., Sater A.K., Schmutz J., Terry A., Vize P.D.,
Warren W.C., Wells D., Wills A., Wilson R.K., Zimmerman L.B.,
Zorn A.M., Grainger R., Grammer T., Khokha M.K., Richardson P.M.,
Rokhsar D.S.;
"The genome of the Western clawed frog Xenopus tropicalis.";
Science 328:633-636(2010).
[2] {ECO:0000313|Ensembl:ENSXETP00000057392}
IDENTIFICATION.
Ensembl;
Submitted (JUN-2011) to UniProtKB.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
ProRule:PRU00108, ECO:0000256|RuleBase:RU004442,
ECO:0000256|SAAS:SAAS00860360}.
-!- SIMILARITY: Belongs to the Antp homeobox family.
{ECO:0000256|RuleBase:RU004442, ECO:0000256|SAAS:SAAS00860374}.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSXETP00000057392}.
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EMBL; AAMC01022443; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 8364.ENSXETP00000057392; -.
PaxDb; F6VMM4; -.
Ensembl; ENSXETT00000057392; ENSXETP00000057392; ENSXETG00000027534.
Xenbase; XB-GENE-486676; hoxa4.
eggNOG; KOG0489; Eukaryota.
eggNOG; ENOG410ZTBY; LUCA.
GeneTree; ENSGT00900000140772; -.
InParanoid; F6VMM4; -.
OrthoDB; EOG091G09XD; -.
TreeFam; TF352857; -.
Proteomes; UP000008143; Unassembled WGS sequence.
Bgee; ENSXETG00000027534; -.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:InterPro.
GO; GO:0007275; P:multicellular organism development; IEA:UniProtKB-KW.
CDD; cd00086; homeodomain; 1.
InterPro; IPR009057; Homeobox-like_sf.
InterPro; IPR017995; Homeobox_antennapedia.
InterPro; IPR001827; Homeobox_Antennapedia_CS.
InterPro; IPR017970; Homeobox_CS.
InterPro; IPR001356; Homeobox_dom.
InterPro; IPR020479; Homeobox_metazoa.
Pfam; PF00046; Homeobox; 1.
PRINTS; PR00025; ANTENNAPEDIA.
PRINTS; PR00024; HOMEOBOX.
SMART; SM00389; HOX; 1.
SUPFAM; SSF46689; SSF46689; 1.
PROSITE; PS00032; ANTENNAPEDIA; 1.
PROSITE; PS00027; HOMEOBOX_1; 1.
PROSITE; PS50071; HOMEOBOX_2; 1.
3: Inferred from homology;
Complete proteome {ECO:0000313|Proteomes:UP000008143};
Developmental protein {ECO:0000256|SAAS:SAAS00860310};
DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU004442, ECO:0000256|SAAS:SAAS00860283};
Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU004442, ECO:0000256|SAAS:SAAS00860291};
Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU004442, ECO:0000256|SAAS:SAAS00860284};
Reference proteome {ECO:0000313|Proteomes:UP000008143}.
DOMAIN 155 215 Homeobox. {ECO:0000259|PROSITE:PS50071}.
DNA_BIND 157 216 Homeobox. {ECO:0000256|PROSITE-
ProRule:PRU00108}.
SEQUENCE 248 AA; 28369 MW; 9828E968188B92C0 CRC64;
MAMSSFLINS NYIEPKFPPC EEYSQNNYLH SQSPEYYERP REPGFEAPPD TLYSGAGSYP
EAGYGYSHIA PPSHEAAATA QDGIPPKGHS QSQQQLLQSH VLRQPPQHCD SLPVPSDSIH
PEKNPAAALK CKEPVVYPWM KKIHVNTVNP NYSGGEPKRS RTAYTRQQVL ELEKEFHFNR
YLTRRRRIEI AHTLCLSERQ VKIWFQNRRM KWKKDHKLPN TKMRSANTPA SNQQSKIQGH
QHTDGPAA


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