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Homeobox D8

 H2P7X7_PONAB            Unreviewed;       237 AA.
H2P7X7;
21-MAR-2012, integrated into UniProtKB/TrEMBL.
21-MAR-2012, sequence version 1.
22-NOV-2017, entry version 37.
SubName: Full=Homeobox D8 {ECO:0000313|Ensembl:ENSPPYP00000014475};
Name=HOXD8 {ECO:0000313|Ensembl:ENSPPYP00000014475};
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Pongo.
NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000014475, ECO:0000313|Proteomes:UP000001595};
[1] {ECO:0000313|Ensembl:ENSPPYP00000014475, ECO:0000313|Proteomes:UP000001595}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Wilson R.K., Mardis E.;
"A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSPPYP00000014475}
IDENTIFICATION.
Ensembl;
Submitted (FEB-2012) to UniProtKB.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
ProRule:PRU00108, ECO:0000256|RuleBase:RU000682,
ECO:0000256|SAAS:SAAS00860360}.
-!- SIMILARITY: Belongs to the Antp homeobox family.
{ECO:0000256|SAAS:SAAS00860374}.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSPPYP00000014475}.
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EMBL; ABGA01155001; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ABGA01155002; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9601.ENSPPYP00000014475; -.
Ensembl; ENSPPYT00000015062; ENSPPYP00000014475; ENSPPYG00000012961.
eggNOG; KOG0489; Eukaryota.
eggNOG; ENOG410ZTBY; LUCA.
GeneTree; ENSGT00900000140792; -.
InParanoid; H2P7X7; -.
OMA; PCGITCH; -.
OrthoDB; EOG091G09XD; -.
TreeFam; TF316310; -.
Proteomes; UP000001595; Chromosome 2b.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
GO; GO:0001228; F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; IEA:Ensembl.
GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
CDD; cd00086; homeodomain; 1.
InterPro; IPR009057; Homeobox-like_sf.
InterPro; IPR001827; Homeobox_Antennapedia_CS.
InterPro; IPR017970; Homeobox_CS.
InterPro; IPR001356; Homeobox_dom.
InterPro; IPR020479; Homeobox_metazoa.
Pfam; PF00046; Homeobox; 1.
PRINTS; PR00024; HOMEOBOX.
SMART; SM00389; HOX; 1.
SUPFAM; SSF46689; SSF46689; 1.
PROSITE; PS00032; ANTENNAPEDIA; 1.
PROSITE; PS00027; HOMEOBOX_1; 1.
PROSITE; PS50071; HOMEOBOX_2; 1.
3: Inferred from homology;
Complete proteome {ECO:0000313|Proteomes:UP000001595};
Developmental protein {ECO:0000256|SAAS:SAAS00860310};
DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860283};
Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860291};
Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860284};
Reference proteome {ECO:0000313|Proteomes:UP000001595}.
DOMAIN 142 202 Homeobox. {ECO:0000259|PROSITE:PS50071}.
DNA_BIND 144 203 Homeobox. {ECO:0000256|PROSITE-
ProRule:PRU00108}.
SEQUENCE 237 AA; 26287 MW; 56E1FA57968F3667 CRC64;
MSSYFVNPLY SKYKAAAAAA AAAAAAGEAI NPTYYDCHFA PEVGGRHAAA AAALQLYGNS
AAGFPHAPPQ AHAHPHPHPH PSPPPSGTGC GGGDCRGQDY FHPGGDPDCN SSFVNMAEDP
DHLNQSSSPS QMFPWMRPQA APGRRRGRQT YSRFQTLELE KEFLFNPYLT RKRRIEVSHA
LALTERQVKI WFQNRRMKWK KENNKDKFPV SRQEVKDGET KKEAQELEED RAEGPTN


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