Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Homer protein homolog 3 (Homer-3) (VASP/Ena-related gene up-regulated during seizure and LTP 3) (Vesl-3)

 HOME3_RAT               Reviewed;         358 AA.
Q9Z2X5;
28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
01-NOV-1999, sequence version 2.
22-NOV-2017, entry version 120.
RecName: Full=Homer protein homolog 3;
Short=Homer-3;
AltName: Full=VASP/Ena-related gene up-regulated during seizure and LTP 3;
Short=Vesl-3;
Name=Homer3; Synonyms=Vesl3;
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=Sprague-Dawley; TISSUE=Hippocampus;
Kato A., Ageta H., Sugiyama H.;
"Rattus norvegicus mRNA for Vesl-3, complete cds.";
Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
[2]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-120 AND SER-158, AND
IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
PubMed=22673903; DOI=10.1038/ncomms1871;
Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A.,
Lundby C., Olsen J.V.;
"Quantitative maps of protein phosphorylation sites across 14
different rat organs and tissues.";
Nat. Commun. 3:876-876(2012).
-!- FUNCTION: Postsynaptic density scaffolding protein. Binds and
cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1,
RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with
ER-associated ITPR1 receptors, it aids the coupling of surface
receptors to intracellular calcium release (By similarity).
{ECO:0000250}.
-!- SUBUNIT: Encodes coiled-coil structures that mediate homo- and
heteromultimerization. {ECO:0000250}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cell junction,
synapse, postsynaptic cell membrane, postsynaptic density
{ECO:0000250}. Cell junction, synapse {ECO:0000250}.
Note=Postsynaptic density of neuronal cells. {ECO:0000250}.
-!- DOMAIN: The WH1 domain interacts with the PPXXF motif in GRM1,
GRM5, RYR1, RYR2, ITPR1, SHANK 1 and SHANK3.
-!- SIMILARITY: Belongs to the Homer family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AB020879; BAA35110.2; -; mRNA.
RefSeq; NP_445762.1; NM_053310.1.
RefSeq; XP_006252953.1; XM_006252891.3.
UniGene; Rn.144573; -.
ProteinModelPortal; Q9Z2X5; -.
SMR; Q9Z2X5; -.
BioGrid; 248182; 4.
CORUM; Q9Z2X5; -.
IntAct; Q9Z2X5; 1.
STRING; 10116.ENSRNOP00000027428; -.
iPTMnet; Q9Z2X5; -.
PhosphoSitePlus; Q9Z2X5; -.
PaxDb; Q9Z2X5; -.
PRIDE; Q9Z2X5; -.
Ensembl; ENSRNOT00000027428; ENSRNOP00000027428; ENSRNOG00000020229.
GeneID; 29548; -.
KEGG; rno:29548; -.
UCSC; RGD:620706; rat.
CTD; 9454; -.
RGD; 620706; Homer3.
eggNOG; ENOG410IIX6; Eukaryota.
eggNOG; ENOG41101PM; LUCA.
GeneTree; ENSGT00390000017850; -.
HOGENOM; HOG000006979; -.
HOVERGEN; HBG051918; -.
InParanoid; Q9Z2X5; -.
KO; K15010; -.
OMA; QDKTELT; -.
OrthoDB; EOG091G0CQ0; -.
PhylomeDB; Q9Z2X5; -.
TreeFam; TF325627; -.
Reactome; R-RNO-6794361; Neurexins and neuroligins.
PRO; PR:Q9Z2X5; -.
Proteomes; UP000002494; Chromosome 16.
Bgee; ENSRNOG00000020229; -.
ExpressionAtlas; Q9Z2X5; baseline and differential.
Genevisible; Q9Z2X5; RN.
GO; GO:0045178; C:basal part of cell; ISO:RGD.
GO; GO:0030054; C:cell junction; IEA:UniProtKB-KW.
GO; GO:0005829; C:cytosol; ISO:RGD.
GO; GO:0014069; C:postsynaptic density; ISO:RGD.
GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO; GO:0035256; F:G-protein coupled glutamate receptor binding; IBA:GO_Central.
GO; GO:0042802; F:identical protein binding; ISO:RGD.
GO; GO:0008022; F:protein C-terminus binding; ISO:RGD.
GO; GO:0019904; F:protein domain specific binding; ISO:RGD.
Gene3D; 2.30.29.30; -; 1.
InterPro; IPR011993; PH-like_dom_sf.
InterPro; IPR000697; WH1/EVH1_dom.
Pfam; PF00568; WH1; 1.
SMART; SM00461; WH1; 1.
SUPFAM; SSF50729; SSF50729; 1.
PROSITE; PS50229; WH1; 1.
1: Evidence at protein level;
Cell junction; Cell membrane; Coiled coil; Complete proteome;
Cytoplasm; Membrane; Phosphoprotein; Postsynaptic cell membrane;
Reference proteome; Synapse.
CHAIN 1 358 Homer protein homolog 3.
/FTId=PRO_0000191013.
DOMAIN 1 113 WH1. {ECO:0000255|PROSITE-
ProRule:PRU00410}.
COILED 95 122 {ECO:0000255}.
COILED 190 355 {ECO:0000255}.
MOD_RES 120 120 Phosphoserine.
{ECO:0000244|PubMed:22673903}.
MOD_RES 158 158 Phosphoserine.
{ECO:0000244|PubMed:22673903}.
SEQUENCE 358 AA; 39891 MW; 4896E23D6A63517E CRC64;
MSTAREQPIF STRAHVFQID PATKRNWIPA GKHALTVSYF YDATRNVYRI ISIGGAKAII
NSTVTPNMTF TKTSQKFGQW ADSRANTVYG LGFGSEQQLT QFAEKFQEVK EAARLAREKS
QDGGELTSTA LAMASHQVPP SPLVSTNGPE EKLFRSQSAD APGPTERERL KKMLSEGSVG
EVQWEAEFFA LQDSNQRLAG ALREANAAAT QWRQQLEVQR AEAEHLRQRV AELEAQVAAE
PVRAGEKEAT SQSVEQLEAR VQTKDQEIQT LKNQSTGPRE APDTAEREET QQQVQDLETR
NAELEQQLRA MESNLEEARA ERERARAEVG RAAQLLDVRL FELSELREGL ARLAEAAP


Related products :

Catalog number Product name Quantity
HOME1_MOUSE ELISA Kit FOR Homer protein homolog 1; organism: Mouse; gene name: Homer1 96T
HOME2_MOUSE ELISA Kit FOR Homer protein homolog 2; organism: Mouse; gene name: Homer2 96T
HOME3_MOUSE ELISA Kit FOR Homer protein homolog 3; organism: Mouse; gene name: Homer3 96T
29-202 HOMER1 is a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function.This gene encodes a member of the homer family of dendri 0.05 mg
29-203 HOMER1 is a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function.This gene encodes a member of the homer family of dendri 0.05 mg
HOMER3 HOMER1 Gene homer homolog 1 (Drosophila)
HOOK1 HOMER3 Gene homer homolog 3 (Drosophila)
HOMEZ HOMER2 Gene homer homolog 2 (Drosophila)
AHP737 RAT ANTI RAT HOMER (aa177_366), Product Type Polyclonal Antibody, Specificity HOMER , Target Species Rat, Host Rat, Format Serum, Isotypes Polyclonal IgG, Applications C, WB, Clone 0.1 ml
AHP736 RAT ANTI RAT HOMER (aa1_186), Product Type Polyclonal Antibody, Specificity HOMER , Target Species Rat, Host Rat, Format Serum, Isotypes Polyclonal IgG, Applications C, WB, Clone 0.1 ml
SCH-AHP736 RAT ANTI RAT HOMER (aa1_186), Product Type Polyclonal Antibody, Specificity HOMER , Target Species Rat, Host Rat, Format Serum, Isotypes Polyclonal IgG, Applications C, WB, Clone 0.1 ml
SCH-AHP737 RAT ANTI RAT HOMER (aa177_366), Product Type Polyclonal Antibody, Specificity HOMER , Target Species Rat, Host Rat, Format Serum, Isotypes Polyclonal IgG, Applications C, WB, Clone 0.1 ml
E15028b Human ELISA Kit FOR Homer protein homolog 2 96T
orb81165 Human Homer Homolog-1 protein Proteins 5
E0631h Human ELISA Kit FOR Homer protein homolog 1 96T
HOME2_MOUSE Mouse ELISA Kit FOR Homer protein homolog 2 96T
HOME1_BOVIN Bovine ELISA Kit FOR Homer protein homolog 1 96T
CSB-RP030074h Recombinant human Homer protein homolog 1 500ug
SPF30_HUMAN Human ELISA Kit FOR Homer protein homolog 1 96T
HOME1_MOUSE Mouse ELISA Kit FOR Homer protein homolog 1 96T
CSB-RP030044h Recombinant human Homer protein homolog 1 500ug
Y050644 Anti_Phospho_HOMER3(Homer protein homolog 3)_(N_terminal) 100ug
CSB-EL010638RA Rat Homer protein homolog 3(HOMER3) ELISA kit 96T
CSB-EL010635RA Rat Homer protein homolog 2(HOMER2) ELISA kit 96T
CSB-EL010634RA Rat Homer protein homolog 1(HOMER1) ELISA kit 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur