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HrnA2 Starter unit polyketide synthase type I module 4 (Partial)

 A0A167RNF2_9ACTN        Unreviewed;      1043 AA.
A0A167RNF2;
06-JUL-2016, integrated into UniProtKB/TrEMBL.
06-JUL-2016, sequence version 1.
25-OCT-2017, entry version 5.
SubName: Full=HrnA2 Starter unit polyketide synthase type I module 4 (Partial) {ECO:0000313|EMBL:SAI82896.1};
Name=hrnA2 {ECO:0000313|EMBL:SAI82896.1};
Streptomyces sp. CMB-0406.
Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
Streptomyces.
NCBI_TaxID=1826667 {ECO:0000313|EMBL:SAI82896.1};
[1] {ECO:0000313|EMBL:SAI82896.1}
NUCLEOTIDE SEQUENCE.
STRAIN=CBM-0406 {ECO:0000313|EMBL:SAI82896.1};
Booth T.J., Alt S., Capon R.J., Wilkinson B.;
"Spontaneous tandem electrocyclisations of the polyene macrolactam
polyketide heronamide C.";
Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
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EMBL; LT548273; SAI82896.1; -; Genomic_DNA.
GO; GO:0048037; F:cofactor binding; IEA:InterPro.
GO; GO:0016740; F:transferase activity; IEA:InterPro.
GO; GO:0008152; P:metabolic process; IEA:InterPro.
Gene3D; 3.30.70.250; -; 1.
Gene3D; 3.40.47.10; -; 2.
InterPro; IPR014043; Acyl_transferase.
InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
InterPro; IPR032821; KAsynt_C_assoc.
InterPro; IPR018201; Ketoacyl_synth_AS.
InterPro; IPR014031; Ketoacyl_synth_C.
InterPro; IPR014030; Ketoacyl_synth_N.
InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
InterPro; IPR020801; PKS_acyl_transferase.
InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
InterPro; IPR020807; PKS_dehydratase.
InterPro; IPR015083; Polyketide_synth_docking.
InterPro; IPR036299; Polyketide_synth_docking_sf.
InterPro; IPR016039; Thiolase-like.
Pfam; PF00698; Acyl_transf_1; 1.
Pfam; PF08990; Docking; 1.
Pfam; PF16197; KAsynt_C_assoc; 1.
Pfam; PF00109; ketoacyl-synt; 1.
Pfam; PF02801; Ketoacyl-synt_C; 1.
Pfam; PF14765; PS-DH; 1.
SMART; SM00827; PKS_AT; 1.
SMART; SM00826; PKS_DH; 1.
SMART; SM00825; PKS_KS; 1.
SUPFAM; SSF101173; SSF101173; 1.
SUPFAM; SSF52151; SSF52151; 2.
SUPFAM; SSF53901; SSF53901; 1.
SUPFAM; SSF55048; SSF55048; 1.
PROSITE; PS00606; B_KETOACYL_SYNTHASE; 1.
4: Predicted;
DOMAIN 35 461 PKS_KS. {ECO:0000259|SMART:SM00825}.
DOMAIN 563 855 PKS_AT. {ECO:0000259|SMART:SM00827}.
DOMAIN 922 1039 PKS_DH. {ECO:0000259|SMART:SM00826}.
SEQUENCE 1043 AA; 110219 MW; 79CDF1C1DE8C93A6 CRC64;
MNEDKLRDYL KRVTADLQRT RQRLAEVESR DSEPIAVVGM ACRFPGGAGT PEELWELVAE
GRDAVGPFPD NRGWDLEELY DADPNASGKT YAREGGFIYD ADRFDSEFFG ISPREALALD
PQQRLLLEIT WETLESAGLA PAELRGSRTG VFSGVSGHEY ASLIHQGPED VEGHLLTGTT
LSVASGRIAY TLGLEGPAVT VDTACSSSLV ALHLACQSLR SGESTMALAG GAAVMPTPGM
FVEFSRQRGL APDGRCKSFA GAADGTIWAE GAGVLLLERL SDAEAKGHRV LAVIRGSAVN
QDGKSSQLSA PNGPAQQRVI QAALAVAGLT PDQVDAVEGH GTGTPLGDPI EAQALLATYG
QSHGADQPLW LGSLKSNIGH AQAAAGIGGV IKMIQAMRHG TLPRTLHVDE PSPQTDWTSG
NVRLLTEARA WPETDHPRRS AVSSFGISGT NAHLILEEAP TPADQAPGTT PEPITVPWLL
SAKTEQGLRD QAQRLVDHVT EHPDLRPADI AYSLVATRTT FEHQAAVVGT TRDELVESLR
ALAQDSGAAS LQGHSRSKKV AFLFTGQGAQ HPGMGRGLYD AYPVFREAFD EVCANLDRHL
KAEVPVKDVV FADDPTLLNQ TRYTQPALFA FQTALTRLLA ADFGVTPTHL IGHSIGEIAA
AHTAGILSLD DACRLVAARG SLMQALPGGG AMLAVEATEE EVVPHLTERV GIAAVNGARS
VVVSGDEEDV DTIGLEFTAQ GRRTRRLTVS HAFHSPHMDP ILGDFHDIAG TLTYHAPRIP
LVSTVTGRPA GSEIIGAAYW TDHIRNTTRF LDGLNQLQEQ GITTFLEIGP DGVLTALTRS
ALPNATAVPL VRPNLPEPAT LLGGLVQAHV CGAAVDWTGF LAGRGARAVS LPTYAFQRRR
HWLEVPDPAG SAAGLGLEPA SHPLLATATE LPDGTRLFTG RVTLAGHAWL ADHTVMGTVI
LPGTAFVELG LHAAQTVGLD EIAELVLNAP ITFGSQSAAL LQVIVGPDDA SAGRSLVIRS
RAEEDHSWTD NATGTLSALT AVA


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