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Ice-structuring protein (Antifreeze protein)

 Q53UJ5_9TELE            Unreviewed;        87 AA.
24-MAY-2005, integrated into UniProtKB/TrEMBL.
24-MAY-2005, sequence version 1.
25-OCT-2017, entry version 35.
RecName: Full=Ice-structuring protein {ECO:0000256|RuleBase:RU362061};
AltName: Full=Antifreeze protein {ECO:0000256|RuleBase:RU362061};
Zoarces elongatus.
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
Eupercaria; Perciformes; Cottioidei; Zoarcales; Zoarcidae; Zoarcinae;
NCBI_TaxID=291231 {ECO:0000313|EMBL:BAD95780.1};
[1] {ECO:0000313|EMBL:BAD95780.1}
PubMed=15654886; DOI=10.1111/j.1742-4658.2004.04490.x;
Nishimiya Y., Sato R., Takamichi M., Miura A., Tsuda S.;
"Co-operative effect of the isoforms of type III antifreeze protein
expressed in Notched-fin eelpout, Zoarces elongatus Kner.";
FEBS J. 272:482-492(2005).
-!- FUNCTION: Lowers the blood freezing point. Contributes to protect
fish blood from freezing at subzero sea water temperatures. Binds
to nascent ice crystals and prevents further growth.
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362061}.
-!- SIMILARITY: Belongs to the type-III AFP family.
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
EMBL; AB188393; BAD95780.1; -; mRNA.
ProteinModelPortal; Q53UJ5; -.
HOVERGEN; HBG004237; -.
GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
InterPro; IPR006190; AFP_Neu5c_C.
InterPro; IPR036732; AFP_Neu5c_C_sf.
InterPro; IPR006013; Antifreeze_III.
InterPro; IPR013974; SAF.
SMART; SM00858; SAF; 1.
SUPFAM; SSF51269; SSF51269; 1.
2: Evidence at transcript level;
Antifreeze protein {ECO:0000256|RuleBase:RU362061};
Secreted {ECO:0000256|RuleBase:RU362061};
Signal {ECO:0000256|RuleBase:RU362061}.
SIGNAL 1 22 {ECO:0000256|RuleBase:RU362061}.
CHAIN 23 87 Ice-structuring protein.
DOMAIN 25 84 AFP-like. {ECO:0000259|PROSITE:PS50844}.
SEQUENCE 87 AA; 9163 MW; A335066DB7228180 CRC64;

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