Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Inositol-tetrakisphosphate 1-kinase 2 (EC 2.7.1.134) (Inositol 1,3,4-trisphosphate 5/6-kinase 2) (Inositol-triphosphate 5/6-kinase 2) (Ins(1,3,4)P(3) 5/6-kinase 2) (OsITP5/6K-2) (OsITPK2) (EC 2.7.1.159) (OsITL1) (Protein DROUGHT- AND SALT-SENSITIVE MUTANT 3) (OsDSM3)

 ITPK2_ORYSJ             Reviewed;         349 AA.
Q10PL5; A0A0P0VUY1; A1KXK8; B9F6M0; Q8GSI5;
04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
22-AUG-2006, sequence version 1.
23-MAY-2018, entry version 89.
RecName: Full=Inositol-tetrakisphosphate 1-kinase 2 {ECO:0000305};
EC=2.7.1.134 {ECO:0000305};
AltName: Full=Inositol 1,3,4-trisphosphate 5/6-kinase 2 {ECO:0000305};
Short=Inositol-triphosphate 5/6-kinase 2 {ECO:0000305};
Short=Ins(1,3,4)P(3) 5/6-kinase 2 {ECO:0000305};
Short=OsITP5/6K-2 {ECO:0000303|PubMed:17961936};
Short=OsITPK2 {ECO:0000303|PubMed:22038091};
EC=2.7.1.159 {ECO:0000305};
AltName: Full=OsITL1 {ECO:0000303|PubMed:18421420};
AltName: Full=Protein DROUGHT- AND SALT-SENSITIVE MUTANT 3 {ECO:0000303|PubMed:22038091};
Short=OsDSM3 {ECO:0000303|PubMed:22038091};
Name=ITPK2;
Synonyms=DSM3 {ECO:0000303|PubMed:22038091},
ITL1 {ECO:0000303|PubMed:18421420};
OrderedLocusNames=Os03g0230500 {ECO:0000312|EMBL:BAF11371.1},
LOC_Os03g12840 {ECO:0000312|EMBL:ABF94780.1};
ORFNames=OJ1017C11.3 {ECO:0000312|EMBL:AAO00682.1},
OJ1781E12.6 {ECO:0000312|EMBL:AAO06958.1},
OsJ_10020 {ECO:0000312|EMBL:EEE58643.1};
Oryza sativa subsp. japonica (Rice).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BOP clade;
Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
NCBI_TaxID=39947;
[1]
NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND INDUCTION.
STRAIN=cv. Zhongzuo-93;
PubMed=18421420; DOI=10.1007/s10529-008-9730-5;
Niu X., Chen Q., Wang X.;
"OsITL1 gene encoding an inositol 1,3,4-trisphosphate 5/6-kinase is a
negative regulator of osmotic stress signaling.";
Biotechnol. Lett. 30:1687-1692(2008).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Nipponbare;
PubMed=16109971; DOI=10.1101/gr.3869505;
The rice chromosome 3 sequencing consortium;
Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R.,
Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L.,
Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S., Johri S.,
Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S.,
Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J.,
de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H.,
Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F.,
Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A.,
Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J.,
Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L.,
Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A.,
Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W.,
Lee H.R., Jiang J., Jackson S.;
"Sequence, annotation, and analysis of synteny between rice chromosome
3 and diverged grass species.";
Genome Res. 15:1284-1291(2005).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Nipponbare;
PubMed=16100779; DOI=10.1038/nature03895;
International rice genome sequencing project (IRGSP);
"The map-based sequence of the rice genome.";
Nature 436:793-800(2005).
[4]
GENOME REANNOTATION.
STRAIN=cv. Nipponbare;
PubMed=18089549; DOI=10.1093/nar/gkm978;
The rice annotation project (RAP);
"The rice annotation project database (RAP-DB): 2008 update.";
Nucleic Acids Res. 36:D1028-D1033(2008).
[5]
GENOME REANNOTATION.
STRAIN=cv. Nipponbare;
PubMed=24280374; DOI=10.1186/1939-8433-6-4;
Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H.,
McCombie W.R., Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S.,
Childs K.L., Davidson R.M., Lin H., Quesada-Ocampo L.,
Vaillancourt B., Sakai H., Lee S.S., Kim J., Numa H., Itoh T.,
Buell C.R., Matsumoto T.;
"Improvement of the Oryza sativa Nipponbare reference genome using
next generation sequence and optical map data.";
Rice 6:4-4(2013).
[6]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Nipponbare;
PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H.,
Cong L., Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J.,
Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X.,
Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y.,
Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J.,
Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y.,
Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y.,
Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z.,
Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T.,
Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H.,
Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W.,
Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L.,
Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J.,
Samudrala R., Wang J., Wong G.K.-S., Yang H.;
"The genomes of Oryza sativa: a history of duplications.";
PLoS Biol. 3:266-281(2005).
[7]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Nipponbare;
PubMed=12869764; DOI=10.1126/science.1081288;
The rice full-length cDNA consortium;
"Collection, mapping, and annotation of over 28,000 cDNA clones from
japonica rice.";
Science 301:376-379(2003).
[8]
TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
PubMed=17961936; DOI=10.1016/j.gene.2007.09.006;
Suzuki M., Tanaka K., Kuwano M., Yoshida K.T.;
"Expression pattern of inositol phosphate-related enzymes in rice
(Oryza sativa L.): implications for the phytic acid biosynthetic
pathway.";
Gene 405:55-64(2007).
[9]
FUNCTION, SUBCELLULAR LOCATION, DISRUPTION PHENOTYPE, GENE FAMILY, AND
NOMENCLATURE.
PubMed=22038091; DOI=10.1007/s11103-011-9830-9;
Du H., Liu L., You L., Yang M., He Y., Li X., Xiong L.;
"Characterization of an inositol 1,3,4-trisphosphate 5/6-kinase gene
that is essential for drought and salt stress responses in rice.";
Plant Mol. Biol. 77:547-563(2011).
-!- FUNCTION: Kinase that can phosphorylate various inositol
polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3 and
participates in phytic acid biosynthesis in developing seeds.
Phytic acid is the primary storage form of phosphorus in cereal
grains and other plant seeds (By similarity). May be involved in
the negative regulation of osmotic stress signaling
(PubMed:18421420, PubMed:22038091). {ECO:0000250|UniProtKB:Q84Y01,
ECO:0000269|PubMed:18421420, ECO:0000269|PubMed:22038091}.
-!- CATALYTIC ACTIVITY: ATP + 1D-myo-inositol 3,4,5,6-
tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-
pentakisphosphate. {ECO:0000305}.
-!- CATALYTIC ACTIVITY: ATP + 1D-myo-inositol 1,3,4-trisphosphate =
ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate. {ECO:0000305}.
-!- CATALYTIC ACTIVITY: ATP + 1D-myo-inositol 1,3,4-trisphosphate =
ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate. {ECO:0000305}.
-!- COFACTOR:
Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
Evidence={ECO:0000250|UniProtKB:Q13572};
Note=Binds 2 magnesium ions per subunit.
{ECO:0000250|UniProtKB:Q13572};
-!- SUBUNIT: Monomer. {ECO:0000250|UniProtKB:Q13572}.
-!- SUBCELLULAR LOCATION: Endoplasmic reticulum
{ECO:0000269|PubMed:22038091}.
-!- TISSUE SPECIFICITY: Expressed in roots, leaves, flowers, anthers
and embryos. {ECO:0000269|PubMed:17961936}.
-!- INDUCTION: By drought and salt stresses.
{ECO:0000269|PubMed:18421420}.
-!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
conditions, but mutant plants show increased sensitivity to salt
and drought stresses. {ECO:0000269|PubMed:22038091}.
-!- SIMILARITY: Belongs to the ITPK1 family. {ECO:0000305}.
-!- SEQUENCE CAUTION:
Sequence=AAO00682.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Sequence=AAO06958.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AY323825; AAQ02374.1; -; mRNA.
EMBL; AC105927; AAO06958.1; ALT_SEQ; Genomic_DNA.
EMBL; AC135157; AAO00682.1; ALT_SEQ; Genomic_DNA.
EMBL; DP000009; ABF94780.1; -; Genomic_DNA.
EMBL; AP008209; BAF11371.1; -; Genomic_DNA.
EMBL; AP014959; BAS83098.1; -; Genomic_DNA.
EMBL; CM000140; EEE58643.1; -; Genomic_DNA.
EMBL; AK100971; BAG94858.1; -; mRNA.
RefSeq; XP_015632763.1; XM_015777277.1.
UniGene; Os.2488; -.
SMR; Q10PL5; -.
STRING; 39947.LOC_Os03g12840.2; -.
PaxDb; Q10PL5; -.
EnsemblPlants; Os03t0230500-01; Os03t0230500-01; Os03g0230500.
GeneID; 4332146; -.
Gramene; Os03t0230500-01; Os03t0230500-01; Os03g0230500.
KEGG; osa:4332146; -.
eggNOG; ENOG410IHA6; Eukaryota.
eggNOG; ENOG4110KIK; LUCA.
HOGENOM; HOG000220790; -.
KO; K00913; -.
OMA; SHEXRES; -.
OrthoDB; EOG09360GWF; -.
BRENDA; 2.7.1.159; 4460.
Reactome; R-OSA-1855167; Synthesis of pyrophosphates in the cytosol.
Reactome; R-OSA-1855204; Synthesis of IP3 and IP4 in the cytosol.
Reactome; R-OSA-983231; Factors involved in megakaryocyte development and platelet production.
Proteomes; UP000059680; Chromosome 3.
ExpressionAtlas; Q10PL5; differential.
Genevisible; Q10PL5; OS.
GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO; GO:0047325; F:inositol tetrakisphosphate 1-kinase activity; IEA:UniProtKB-EC.
GO; GO:0052726; F:inositol-1,3,4-trisphosphate 5-kinase activity; IEA:UniProtKB-EC.
GO; GO:0052725; F:inositol-1,3,4-trisphosphate 6-kinase activity; IEA:UniProtKB-EC.
GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO; GO:0032957; P:inositol trisphosphate metabolic process; IEA:InterPro.
GO; GO:0047484; P:regulation of response to osmotic stress; IMP:UniProtKB.
InterPro; IPR008656; Inositol_tetrakis-P_1-kinase.
PANTHER; PTHR14217; PTHR14217; 1.
Pfam; PF05770; Ins134_P3_kin; 1.
PIRSF; PIRSF038186; ITPK; 1.
2: Evidence at transcript level;
ATP-binding; Complete proteome; Endoplasmic reticulum; Kinase;
Magnesium; Metal-binding; Nucleotide-binding; Reference proteome;
Transferase.
CHAIN 1 349 Inositol-tetrakisphosphate 1-kinase 2.
/FTId=PRO_0000431871.
NP_BIND 207 218 ATP. {ECO:0000250|UniProtKB:Q13572}.
METAL 298 298 Magnesium 1.
{ECO:0000250|UniProtKB:Q13572}.
METAL 313 313 Magnesium 1.
{ECO:0000250|UniProtKB:Q13572}.
METAL 313 313 Magnesium 2.
{ECO:0000250|UniProtKB:Q13572}.
METAL 315 315 Magnesium 2.
{ECO:0000250|UniProtKB:Q13572}.
BINDING 48 48 1D-myo-inositol 1,3,4-trisphosphate.
{ECO:0000250|UniProtKB:Q9XYQ1}.
BINDING 90 90 1D-myo-inositol 1,3,4-trisphosphate.
{ECO:0000250|UniProtKB:Q9XYQ1}.
BINDING 125 125 ATP. {ECO:0000250|UniProtKB:Q13572}.
BINDING 175 175 ATP. {ECO:0000250|UniProtKB:Q13572}.
BINDING 186 186 1D-myo-inositol 1,3,4-trisphosphate.
{ECO:0000250|UniProtKB:Q9XYQ1}.
BINDING 218 218 1D-myo-inositol 1,3,4-trisphosphate.
{ECO:0000250|UniProtKB:Q9XYQ1}.
BINDING 233 233 ATP. {ECO:0000250|UniProtKB:Q13572}.
BINDING 315 315 1D-myo-inositol 1,3,4-trisphosphate.
{ECO:0000250|UniProtKB:Q9XYQ1}.
CONFLICT 20 20 P -> Q (in Ref. 6; EEE58643).
{ECO:0000305}.
SEQUENCE 349 AA; 38800 MW; 6759CDB676A83E67 CRC64;
MRLHGEVSFD EDEEEVVMVP AAALSSSPLN GGAVPVTRLV VGYALTKKKV KSFLQPNLLL
LARKKGINLV AIDDTRPLAE QGPFDVILHK ITSKEWQQVL EDYHEEHPEV TVLDPPNAIN
HLNNRQSMLA EVSDLNLSSF YGEVCTPRQL VIMRDPSSIP TAVAMAGLTL PLVAKPLVVD
GTSKSHELSL AYDEASLSML DPPLVLQEFV NHGGILFKVY IIGETIQVVR RFSLPDVNTY
DLLNNVGVYR FPRVSCAAAS ADHADLDPHI SELPPRPLLE KLGKELRGRL GLRLFNIDMI
RELGTKDRYY IIDINYFPGF GKMPGYEHIF TDFLLNLAQS KYKKCLSGG


Related products :

Catalog number Product name Quantity
pka-040 Recombinant Human Inositol-Tetrakisphosphate 1-Kinase PROTEIN KINASES 20
pka-040 Recombinant Human Inositol-Tetrakisphosphate 1-Kinase PROTEIN KINASES 1mg
pka-040 Recombinant Human Inositol-Tetrakisphosphate 1-Kinase PROTEIN KINASES 5
pka-040 Recombinant Human Inositol-Tetrakisphosphate 1-Kinase 5
RPK-040 Recombinant Human Inositol-Tetrakisphosphate 1-Kinase 5
pka-040 Recombinant Human Inositol-Tetrakisphosphate 1-Kinase 1mg
pka-040 Recombinant Human Inositol-Tetrakisphosphate 1-Kinase 20
ITPK1_MOUSE Mouse ELISA Kit FOR Inositol-tetrakisphosphate 1-kinase 96T
CSB-EL011908CH Chicken Inositol-tetrakisphosphate 1-kinase(ITPK1) ELISA kit 96T
CSB-EL011908HU Human Inositol-tetrakisphosphate 1-kinase(ITPK1) ELISA kit 96T
CSB-EL011908MO Mouse Inositol-tetrakisphosphate 1-kinase(ITPK1) ELISA kit 96T
CSB-EL011908BO Bovine Inositol-tetrakisphosphate 1-kinase(ITPK1) ELISA kit 96T
26-957 ITPK1 is the kinase that can phosphorylate various inositol polyphosphate such as Ins (3,4,5,6)P4 or Ins (1,3,4)P3. It may also act as an isomerase that interconverts the inositol tetraphosphate isome 0.05 mg
CSB-EL011908MO Mouse Inositol-tetrakisphosphate 1-kinase(ITPK1) ELISA kit SpeciesMouse 96T
CSB-EL011908CH Chicken Inositol-tetrakisphosphate 1-kinase(ITPK1) ELISA kit SpeciesChicken 96T
CSB-EL011908BO Bovine Inositol-tetrakisphosphate 1-kinase(ITPK1) ELISA kit SpeciesBovine 96T
CSB-EL011908HU Human Inositol-tetrakisphosphate 1-kinase(ITPK1) ELISA kit SpeciesHuman 96T
ITPK1_MOUSE ELISA Kit FOR Inositol-tetrakisphosphate 1-kinase; organism: Mouse; gene name: Itpk1 96T
201-20-2867 ITPKC{inositol 1,4,5-trisphosphate 3-kinase C}rabbit.pAb 0.2ml
E15032m Mouse ELISA Kit FOR Inositol-trisphosphate 3-kinase A 96T
CSB-EL011909RA Rat Inositol-trisphosphate 3-kinase A(ITPKA) ELISA kit 96T
201-20-2865 ITPKA{inositol 1,4,5-trisphosphate 3-kinase A}rabbit.pAb 0.2ml
ITPR2 ITPKC Gene inositol 1,4,5-trisphosphate 3-kinase C
CSB-EL011911RA Rat Inositol-trisphosphate 3-kinase C(ITPKC) ELISA kit 96T
ITPR1 ITPKB Gene inositol 1,4,5-trisphosphate 3-kinase B


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur