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Integral membrane protein 1 (STT3A, subunit of the oligosaccharyltransferase complex (catalytic))

 Q6NX25_XENTR            Unreviewed;       705 AA.
Q6NX25;
05-JUL-2004, integrated into UniProtKB/TrEMBL.
05-JUL-2004, sequence version 1.
22-NOV-2017, entry version 76.
SubName: Full=Integral membrane protein 1 {ECO:0000313|EMBL:CAJ82849.1};
SubName: Full=STT3A, subunit of the oligosaccharyltransferase complex (catalytic) {ECO:0000313|Ensembl:ENSXETP00000058477};
Name=stt3a {ECO:0000313|Ensembl:ENSXETP00000058477,
ECO:0000313|Xenbase:XB-GENE-973638};
Synonyms=itm1 {ECO:0000313|EMBL:CAJ82849.1},
MGC76056 {ECO:0000313|EMBL:AAH67313.1};
ORFNames=TNeu111d10.1-001 {ECO:0000313|EMBL:CAJ82849.1};
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
Silurana.
NCBI_TaxID=8364 {ECO:0000313|EMBL:AAH67313.1};
[1] {ECO:0000313|EMBL:AAH67313.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Embryo {ECO:0000313|EMBL:AAH67313.1};
NIH - Xenopus Gene Collection (XGC) project;
Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|EMBL:CAJ82849.1}
NUCLEOTIDE SEQUENCE.
Amaya E., Ashurst J.L., Bonfield J.K., Croning M.D.R., Chen C-K.,
Davies R.M., Francis M.D., Garrett N., Gilchrist M.J., Grafham D.V.,
McLaren S.R., Papalopulu N., Rogers J., Smith J.C., Taylor R.G.,
Voigt J., Zorn A.M.;
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|Ensembl:ENSXETP00000058477}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000058477};
PubMed=20431018; DOI=10.1126/science.1183670;
Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L.,
Blitz I.L., Blumberg B., Dichmann D.S., Dubchak I., Amaya E.,
Detter J.C., Fletcher R., Gerhard D.S., Goodstein D., Graves T.,
Grigoriev I.V., Grimwood J., Kawashima T., Lindquist E., Lucas S.M.,
Mead P.E., Mitros T., Ogino H., Ohta Y., Poliakov A.V., Pollet N.,
Robert J., Salamov A., Sater A.K., Schmutz J., Terry A., Vize P.D.,
Warren W.C., Wells D., Wills A., Wilson R.K., Zimmerman L.B.,
Zorn A.M., Grainger R., Grammer T., Khokha M.K., Richardson P.M.,
Rokhsar D.S.;
"The genome of the Western clawed frog Xenopus tropicalis.";
Science 328:633-636(2010).
[4] {ECO:0000313|Ensembl:ENSXETP00000058477}
IDENTIFICATION.
Ensembl;
Submitted (JUN-2011) to UniProtKB.
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EMBL; AAMC01071035; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; BC067313; AAH67313.1; -; mRNA.
EMBL; CR760376; CAJ82849.1; -; mRNA.
RefSeq; NP_001001202.1; NM_001001202.1.
RefSeq; XP_012821774.1; XM_012966320.2.
UniGene; Str.26385; -.
CAZy; GT66; Glycosyltransferase Family 66.
Ensembl; ENSXETT00000062199; ENSXETP00000058477; ENSXETG00000017775.
GeneID; 407861; -.
CTD; 3703; -.
Xenbase; XB-GENE-973638; stt3a.
eggNOG; KOG2292; Eukaryota.
eggNOG; COG1287; LUCA.
GeneTree; ENSGT00390000015238; -.
HOGENOM; HOG000157471; -.
HOVERGEN; HBG010606; -.
Proteomes; UP000008143; Unassembled WGS sequence.
Bgee; ENSXETG00000017775; -.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0008250; C:oligosaccharyltransferase complex; ISS:UniProtKB.
GO; GO:0004576; F:oligosaccharyl transferase activity; IEA:InterPro.
GO; GO:0018279; P:protein N-linked glycosylation via asparagine; ISS:UniProtKB.
InterPro; IPR003674; Oligo_trans_STT3.
Pfam; PF02516; STT3; 1.
2: Evidence at transcript level;
Complete proteome {ECO:0000313|Proteomes:UP000008143};
Membrane {ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000008143};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
TRANSMEM 20 41 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 83 103 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 115 135 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 141 158 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 170 186 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 192 225 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 237 256 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 268 286 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 298 319 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 360 379 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 386 404 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 410 430 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 451 473 Helical. {ECO:0000256|SAM:Phobius}.
SEQUENCE 705 AA; 80628 MW; 66D9535EC0578F36 CRC64;
MTKLGFLRLS YEKQDTLLKL LILSMAAILS FSTRLFSVLR FESVIHEFDP YFNYRTTRFL
AEEGFYNFHN WFDDRAWYPL GRIIGGTIYP GLMITSAAFY HILHFFHITI DIRNVCVFLA
PLFSSFTTIV TYHLTKELKD AGAGLLAAAM IAVVPGYISR SVAGSYDNEG IAIFCMLLTY
YMWIKAVKTG SIYWAAMCAL AYFYMVSSWG GYVFLINLIP LHVLVLMLTG RFSHRIYVAY
CTVYCLGTIL SMQISFVGFQ PVLSSEHMAA LGVFGLCQIH AFVDYLRSKL NPQQFEILFR
SVISLVGFVL LTVGAVLMLT GKISPWTGRF YSLLDPSYAK NNIPIIASVS EHQPTTWSSY
YFDLQLLVFM FPVGLYYCFS NLSDARIFII MYGVTSMYFS AVMVRLMLVL APVMCILSGI
GVSQVLSTYM KNLDISRPDK KTKKQQDSTY PIKNEVASGM ILVMAFFLVT YTFHSTWVTS
EAYSSPSIVL SARGGDGSRI IFDDFREAYY WLRHNTPEDA KVMSWWDYGY QITAMANRTI
LVDNNTWNNT HISRVGQAMA STEEKAYEIM RELDVSYVLV IFGGLTGYSS DDINKFLWMV
RIGGSTDTGK HIKEHDYYTP TGEFRVDREG SPVLLNCLMY KMCYYRFGQV YTEAKRPPGY
DRVRNAEIGN KDFELDVLEE AYTTEHWLVR IYKVKDLDNR GLSRT


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