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Integrin alpha-V (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]

 ITAV_MOUSE              Reviewed;        1044 AA.
P43406; A2AKI6;
01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
27-JUL-2011, sequence version 2.
27-SEP-2017, entry version 162.
RecName: Full=Integrin alpha-V;
AltName: Full=Vitronectin receptor subunit alpha;
AltName: CD_antigen=CD51;
Contains:
RecName: Full=Integrin alpha-V heavy chain;
Contains:
RecName: Full=Integrin alpha-V light chain;
Flags: Precursor;
Name=Itgav;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=CD-1; TISSUE=Kidney;
PubMed=8601592; DOI=10.1083/jcb.132.6.1161;
Wada J., Kumar A., Liu Z., Ruoslahti E., Reichardt L., Marvaldi J.,
Kanwar Y.S.;
"Cloning of mouse integrin alphaV cDNA and role of the alphaV-related
matrix receptors in metanephric development.";
J. Cell Biol. 132:1161-1176(1996).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=C57BL/6J;
PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
Lindblad-Toh K., Eichler E.E., Ponting C.P.;
"Lineage-specific biology revealed by a finished genome assembly of
the mouse.";
PLoS Biol. 7:E1000112-E1000112(2009).
[3]
FUNCTION, AND DISRUPTION PHENOTYPE.
PubMed=9827803; DOI=10.1016/S0092-8674(00)81618-9;
Bader B.L., Rayburn H., Crowley D., Hynes R.O.;
"Extensive vasculogenesis, angiogenesis, and organogenesis precede
lethality in mice lacking all alpha v integrins.";
Cell 95:507-519(1998).
[4]
INTERACTION WITH FBLN5.
PubMed=11805835; DOI=10.1038/415171a;
Nakamura T., Lozano P.R., Ikeda Y., Iwanaga Y., Hinek A.,
Minamisawa S., Cheng C.F., Kobuke K., Dalton N., Takada Y.,
Tashiro K., Ross J., Honjo T., Chien K.R.;
"Fibulin-5/DANCE is essential for elastogenesis in vivo.";
Nature 415:171-175(2002).
[5]
GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-74; ASN-615; ASN-869;
ASN-939 AND ASN-941.
TISSUE=Myoblast;
PubMed=19656770; DOI=10.1074/mcp.M900195-MCP200;
Gundry R.L., Raginski K., Tarasova Y., Tchernyshyov I.,
Bausch-Fluck D., Elliott S.T., Boheler K.R., Van Eyk J.E.,
Wollscheid B.;
"The mouse C2C12 myoblast cell surface N-linked glycoproteome:
identification, glycosite occupancy, and membrane orientation.";
Mol. Cell. Proteomics 8:2555-2569(2009).
[6]
GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-74; ASN-615 AND ASN-869.
PubMed=19349973; DOI=10.1038/nbt.1532;
Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M.,
Schiess R., Aebersold R., Watts J.D.;
"Mass-spectrometric identification and relative quantification of N-
linked cell surface glycoproteins.";
Nat. Biotechnol. 27:378-386(2009).
[7]
IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung,
Pancreas, Spleen, and Testis;
PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
"A tissue-specific atlas of mouse protein phosphorylation and
expression.";
Cell 143:1174-1189(2010).
-!- FUNCTION: The alpha-V (ITGAV) integrins are receptors for
vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix
metalloproteinase-2, osteopontin, osteomodulin, prothrombin,
thrombospondin and vWF. They recognize the sequence R-G-D in a
wide array of ligands. Alpha-V integrins may play a role in embryo
implantation, angiogenesis and wound healing (PubMed:9827803).
ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its
coreceptor in CX3CR1-dependent fractalkine signaling. ITGAV:ITGB3
binds to NRG1 (via EGF domain) and this binding is essential for
NRG1-ERBB signaling. ITGAV:ITGB3 binds to FGF1 and this binding is
essential for FGF1 signaling. ITGAV:ITGB3 binds to IGF1 and this
binding is essential for IGF1 signaling (By similarity).
ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct
from the classical ligand-binding site (site 1) and this induces
integrin conformational changes and enhanced ligand binding to
site 1 (By similarity). ITGAV:ITGB3 and ITGAV:ITGB6 act as a
receptor for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell
adhesion to FBN1. {ECO:0000250|UniProtKB:P06756,
ECO:0000269|PubMed:9827803}.
-!- SUBUNIT: Heterodimer of an alpha and a beta subunit. The alpha
subunit is composed of a heavy and a light chain linked by a
disulfide bond. Alpha-V (ITGAV) associates with either beta-1
(ITGB1), beta-3 (ITGB3), beta-5 (ITGB5), beta-6 (ITGB6) or beta-8
(ITGB8) (Probable). Interacts with RAB25. Interacts with CIB1 (By
similarity). Integrins ITGAV:ITGB3 and ITGAV:ITGB5 interact with
FBLN5 (via N-terminus)(PubMed:11805835). ITGAV:ITGB3 and
ITGAV:ITGB5 interact with NOV (By similarity). ITGAV:ITGB3
interacts with ADGRA2 (By similarity). ITGAV:ITGB3 is found in a
ternary complex with CX3CR1 and CX3CL1. ITGAV:ITGB3 is found in a
ternary complex with NRG1 and ERBB3. ITGAV:ITGB3 is found in a
ternary complex with FGF1 and FGFR1. ITGAV:ITGB3 is found in a
ternary complex with IGF1 and IGF1R (By similarity). ITGAV:ITGB3
and ITGAV:ITGB6 interact with FBN1 (By similarity).
{ECO:0000250|UniProtKB:P06756, ECO:0000269|PubMed:11805835,
ECO:0000305|PubMed:11805835}.
-!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane
protein. Cell junction, focal adhesion
{ECO:0000250|UniProtKB:P06756}.
-!- DISRUPTION PHENOTYPE: Mice expressing a null mutation of the
alpha-V subunit gene survive until late in embryonic development
and occasionally even to birth. They demonstrate cleft palate, and
defective development of CNS and gastrointestinal blood vessels.
{ECO:0000269|PubMed:9827803}.
-!- SIMILARITY: Belongs to the integrin alpha chain family.
{ECO:0000305}.
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EMBL; U14135; AAC52497.1; -; mRNA.
EMBL; AL772301; CAM13680.1; -; Genomic_DNA.
CCDS; CCDS16181.1; -.
PIR; T10050; T10050.
RefSeq; NP_032428.2; NM_008402.3.
UniGene; Mm.227; -.
ProteinModelPortal; P43406; -.
SMR; P43406; -.
CORUM; P43406; -.
IntAct; P43406; 4.
MINT; MINT-4098999; -.
STRING; 10090.ENSMUSP00000028499; -.
iPTMnet; P43406; -.
PhosphoSitePlus; P43406; -.
EPD; P43406; -.
MaxQB; P43406; -.
PaxDb; P43406; -.
PeptideAtlas; P43406; -.
PRIDE; P43406; -.
DNASU; 16410; -.
Ensembl; ENSMUST00000028499; ENSMUSP00000028499; ENSMUSG00000027087.
GeneID; 16410; -.
KEGG; mmu:16410; -.
UCSC; uc008kid.2; mouse.
CTD; 3685; -.
MGI; MGI:96608; Itgav.
eggNOG; KOG3637; Eukaryota.
eggNOG; ENOG410XPVZ; LUCA.
GeneTree; ENSGT00760000118782; -.
HOGENOM; HOG000231603; -.
HOVERGEN; HBG006186; -.
InParanoid; P43406; -.
KO; K06487; -.
OMA; SCFNVRF; -.
OrthoDB; EOG091G05Z4; -.
TreeFam; TF105391; -.
Reactome; R-MMU-1236973; Cross-presentation of particulate exogenous antigens (phagosomes).
Reactome; R-MMU-1566948; Elastic fibre formation.
Reactome; R-MMU-2129379; Molecules associated with elastic fibres.
Reactome; R-MMU-216083; Integrin cell surface interactions.
Reactome; R-MMU-3000170; Syndecan interactions.
Reactome; R-MMU-3000178; ECM proteoglycans.
Reactome; R-MMU-4420097; VEGFA-VEGFR2 Pathway.
Reactome; R-MMU-445144; Signal transduction by L1.
Reactome; R-MMU-6798695; Neutrophil degranulation.
ChiTaRS; Itgav; mouse.
PRO; PR:P43406; -.
Proteomes; UP000000589; Chromosome 2.
Bgee; ENSMUSG00000027087; -.
CleanEx; MM_ITGAV; -.
ExpressionAtlas; P43406; baseline and differential.
Genevisible; P43406; MM.
GO; GO:0035867; C:alphav-beta3 integrin-IGF-1-IGF1R complex; ISO:MGI.
GO; GO:0009986; C:cell surface; ISS:BHF-UCL.
GO; GO:0005829; C:cytosol; ISO:MGI.
GO; GO:0009897; C:external side of plasma membrane; IDA:MGI.
GO; GO:0070062; C:extracellular exosome; ISO:MGI.
GO; GO:0031527; C:filopodium membrane; ISO:MGI.
GO; GO:0005925; C:focal adhesion; ISS:UniProtKB.
GO; GO:0034683; C:integrin alphav-beta3 complex; ISO:MGI.
GO; GO:0034684; C:integrin alphav-beta5 complex; ISO:MGI.
GO; GO:0034685; C:integrin alphav-beta6 complex; IDA:CAFA.
GO; GO:0034686; C:integrin alphav-beta8 complex; ISO:MGI.
GO; GO:0008305; C:integrin complex; ISS:BHF-UCL.
GO; GO:0031258; C:lamellipodium membrane; ISO:MGI.
GO; GO:0016020; C:membrane; IDA:BHF-UCL.
GO; GO:0031528; C:microvillus membrane; ISO:MGI.
GO; GO:0005886; C:plasma membrane; IDA:MGI.
GO; GO:0032587; C:ruffle membrane; ISO:MGI.
GO; GO:0019960; F:C-X3-C chemokine binding; IEA:Ensembl.
GO; GO:0050840; F:extracellular matrix binding; ISO:MGI.
GO; GO:1990430; F:extracellular matrix protein binding; ISO:MGI.
GO; GO:0017134; F:fibroblast growth factor binding; IEA:Ensembl.
GO; GO:0001968; F:fibronectin binding; ISO:MGI.
GO; GO:0031994; F:insulin-like growth factor I binding; IEA:Ensembl.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0038132; F:neuregulin binding; IEA:Ensembl.
GO; GO:0042277; F:peptide binding; IEA:Ensembl.
GO; GO:0002020; F:protease binding; ISO:MGI.
GO; GO:0046982; F:protein heterodimerization activity; TAS:BHF-UCL.
GO; GO:0005102; F:receptor binding; IEA:Ensembl.
GO; GO:0050431; F:transforming growth factor beta binding; ISS:BHF-UCL.
GO; GO:0005245; F:voltage-gated calcium channel activity; ISO:MGI.
GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
GO; GO:0038027; P:apolipoprotein A-I-mediated signaling pathway; ISO:MGI.
GO; GO:0043277; P:apoptotic cell clearance; IMP:MGI.
GO; GO:0001568; P:blood vessel development; IMP:MGI.
GO; GO:0070588; P:calcium ion transmembrane transport; ISO:MGI.
GO; GO:0007155; P:cell adhesion; ISS:BHF-UCL.
GO; GO:0033627; P:cell adhesion mediated by integrin; IDA:CAFA.
GO; GO:0016049; P:cell growth; ISO:MGI.
GO; GO:0016477; P:cell migration; ISO:MGI.
GO; GO:0007160; P:cell-matrix adhesion; ISO:MGI.
GO; GO:0031589; P:cell-substrate adhesion; ISO:MGI.
GO; GO:0032490; P:detection of molecule of bacterial origin; TAS:BHF-UCL.
GO; GO:0035987; P:endodermal cell differentiation; ISO:MGI.
GO; GO:0043542; P:endothelial cell migration; TAS:BHF-UCL.
GO; GO:0070371; P:ERK1 and ERK2 cascade; IDA:BHF-UCL.
GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IDA:BHF-UCL.
GO; GO:0009566; P:fertilization; NAS:BHF-UCL.
GO; GO:0048041; P:focal adhesion assembly; NAS:BHF-UCL.
GO; GO:0035262; P:gonad morphogenesis; NAS:BHF-UCL.
GO; GO:0034113; P:heterotypic cell-cell adhesion; ISO:MGI.
GO; GO:0006954; P:inflammatory response; TAS:BHF-UCL.
GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
GO; GO:0050919; P:negative chemotaxis; ISO:MGI.
GO; GO:2000536; P:negative regulation of entry of bacterium into host cell; ISS:BHF-UCL.
GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; ISO:MGI.
GO; GO:0010888; P:negative regulation of lipid storage; ISS:BHF-UCL.
GO; GO:0032369; P:negative regulation of lipid transport; ISS:BHF-UCL.
GO; GO:0050748; P:negative regulation of lipoprotein metabolic process; ISS:BHF-UCL.
GO; GO:0045715; P:negative regulation of low-density lipoprotein particle receptor biosynthetic process; ISS:BHF-UCL.
GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; ISS:BHF-UCL.
GO; GO:0045785; P:positive regulation of cell adhesion; ISS:BHF-UCL.
GO; GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.
GO; GO:0008284; P:positive regulation of cell proliferation; ISS:BHF-UCL.
GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
GO; GO:0033690; P:positive regulation of osteoblast proliferation; IMP:BHF-UCL.
GO; GO:2000425; P:regulation of apoptotic cell clearance; IDA:BHF-UCL.
GO; GO:0045124; P:regulation of bone resorption; TAS:BHF-UCL.
GO; GO:0050764; P:regulation of phagocytosis; ISS:BHF-UCL.
GO; GO:0051209; P:release of sequestered calcium ion into cytosol; TAS:BHF-UCL.
GO; GO:0071731; P:response to nitric oxide; TAS:BHF-UCL.
GO; GO:0034446; P:substrate adhesion-dependent cell spreading; ISO:MGI.
GO; GO:0042110; P:T cell activation; TAS:BHF-UCL.
GO; GO:0038044; P:transforming growth factor-beta secretion; IDA:CAFA.
GO; GO:0060707; P:trophoblast giant cell differentiation; TAS:BHF-UCL.
GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
GO; GO:0046718; P:viral entry into host cell; ISO:MGI.
InterPro; IPR013517; FG-GAP.
InterPro; IPR013519; Int_alpha_beta-p.
InterPro; IPR000413; Integrin_alpha.
InterPro; IPR013649; Integrin_alpha-2.
InterPro; IPR018184; Integrin_alpha_C_CS.
InterPro; IPR032695; Integrin_dom.
Pfam; PF01839; FG-GAP; 3.
Pfam; PF00357; Integrin_alpha; 1.
Pfam; PF08441; Integrin_alpha2; 1.
PRINTS; PR01185; INTEGRINA.
SMART; SM00191; Int_alpha; 5.
SUPFAM; SSF69179; SSF69179; 3.
PROSITE; PS51470; FG_GAP; 7.
PROSITE; PS00242; INTEGRIN_ALPHA; 1.
1: Evidence at protein level;
Angiogenesis; Calcium; Cell adhesion; Cell junction;
Cleavage on pair of basic residues; Complete proteome;
Developmental protein; Differentiation; Disulfide bond; Glycoprotein;
Integrin; Membrane; Metal-binding; Receptor; Reference proteome;
Repeat; Signal; Transmembrane; Transmembrane helix.
SIGNAL 1 30 {ECO:0000250}.
CHAIN 31 1044 Integrin alpha-V.
/FTId=PRO_0000016304.
CHAIN 31 885 Integrin alpha-V heavy chain.
{ECO:0000250}.
/FTId=PRO_0000016305.
CHAIN 887 1044 Integrin alpha-V light chain.
{ECO:0000250}.
/FTId=PRO_0000016306.
TOPO_DOM 31 988 Extracellular. {ECO:0000255}.
TRANSMEM 989 1012 Helical. {ECO:0000255}.
TOPO_DOM 1013 1044 Cytoplasmic. {ECO:0000255}.
REPEAT 32 98 FG-GAP 1. {ECO:0000255|PROSITE-
ProRule:PRU00803}.
REPEAT 109 170 FG-GAP 2. {ECO:0000255|PROSITE-
ProRule:PRU00803}.
REPEAT 173 225 FG-GAP 3. {ECO:0000255|PROSITE-
ProRule:PRU00803}.
REPEAT 237 291 FG-GAP 4. {ECO:0000255|PROSITE-
ProRule:PRU00803}.
REPEAT 292 357 FG-GAP 5. {ECO:0000255|PROSITE-
ProRule:PRU00803}.
REPEAT 358 415 FG-GAP 6. {ECO:0000255|PROSITE-
ProRule:PRU00803}.
REPEAT 419 482 FG-GAP 7. {ECO:0000255|PROSITE-
ProRule:PRU00803}.
CA_BIND 260 268 {ECO:0000255}.
CA_BIND 314 322 {ECO:0000255}.
CA_BIND 379 387 {ECO:0000255}.
CA_BIND 443 451 {ECO:0000255}.
MOTIF 1015 1019 GFFKR motif.
CARBOHYD 74 74 N-linked (GlcNAc...) asparagine.
{ECO:0000269|PubMed:19349973,
ECO:0000269|PubMed:19656770}.
CARBOHYD 290 290 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 296 296 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 615 615 N-linked (GlcNAc...) asparagine.
{ECO:0000269|PubMed:19349973,
ECO:0000269|PubMed:19656770}.
CARBOHYD 704 704 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 835 835 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 851 851 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 869 869 N-linked (GlcNAc...) asparagine.
{ECO:0000269|PubMed:19349973,
ECO:0000269|PubMed:19656770}.
CARBOHYD 939 939 N-linked (GlcNAc...) asparagine;
atypical. {ECO:0000269|PubMed:19656770}.
CARBOHYD 941 941 N-linked (GlcNAc...) asparagine.
{ECO:0000269|PubMed:19656770}.
CARBOHYD 969 969 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 976 976 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 89 97 {ECO:0000250}.
DISULFID 138 158 {ECO:0000250}.
DISULFID 172 185 {ECO:0000250}.
DISULFID 491 502 {ECO:0000250}.
DISULFID 508 565 {ECO:0000250}.
DISULFID 626 632 {ECO:0000250}.
DISULFID 698 711 {ECO:0000250}.
DISULFID 852 900 Interchain (between heavy and light
chains). {ECO:0000250}.
DISULFID 905 910 {ECO:0000250}.
CONFLICT 526 527 EL -> DV (in Ref. 1; AAC52497).
{ECO:0000305}.
CONFLICT 768 769 VL -> EK (in Ref. 1; AAC52497).
{ECO:0000305}.
CONFLICT 872 872 A -> G (in Ref. 1; AAC52497).
{ECO:0000305}.
CONFLICT 880 880 N -> S (in Ref. 1; AAC52497).
{ECO:0000305}.
CONFLICT 887 887 D -> G (in Ref. 1; AAC52497).
{ECO:0000305}.
SEQUENCE 1044 AA; 115360 MW; 417FD73D776B5918 CRC64;
MAAPGRLLLR PRPGGLLLLL PGLLLPLADA FNLDVESPAE YAGPEGSYFG FAVDFFEPST
SSRMFLLVGA PKANTTQPGI VEGGQVLKCE CSSSRRCQPI EFDSTGNRDY AKDDPLEFKS
HQWFGASVRS KQDKILACAP LYHWRTEMKQ EREPVGTCFL QDGTKTVEYA PCRSKNIDAD
GQGFCQGGFS IDFTKADRVL LGGPGSFYWQ GQLISDQVAE IISKYDPNVY SIKYNNQLAT
RTAQAIFDDS YLGYSVAVGD FNGDGIEDFV SGVPRAARTL GMVYIYDGKN MSSLHNFTGE
QMAAYFGFSV AATDINGDDY ADVFIGAPLF MDRGSDGKLQ EVGQVSVSLQ RAVGDFQTTK
LNGFEVFARF GSAIAPLGDL DQDGFNDIAI AAPYGGEDKK GLVYIFNGRS TGLNSVPSQI
LEGQWAAQSM PPSFGYSMKG ATDVDRNGYP DLVVGAFGVD RAVLYRARPV VTVNAGLEVY
PSILNQDNKI CPLPGTALKV SCFNVRFCLK ADGKGTLPRK LHFQVELLLD KLKQKGAIRR
ALFLHNRSPV HSKTMTVFRG GQMQCEELVA YLRDESEFRD KLTPITIFME YRLDQRTAAD
ATGLQPILNQ FTPANVSRQA HILLDCGEDN VCKPKLEVSV NSDQKKIYIG DDNPLTLTVK
AQNQGEGAYE AELIVSIPPQ ADFIGVVRNN EALARLSCAF KTENQTRQVV CDLGNPMKAG
TQLLAGLRFS VHQQSEMDTS VKFDLKIQSS NSFDNVSPVV SYKVDLAVLA AVEIRGVSSP
DHIFLPIPNW EYKENPETEE DVGPIVQHIY ELRNNGPSSF SKAILNLQWP YKYNNNTLLY
ILHYDIDGPM NCTADTEINP LRIKTPEKND TAAAGQGERN HLITKRDLTL REGDVHTLGC
GIAKCLQITC QVGRLDRGKS AILYVKSLLW TETFMNKENQ NHSYSLKSSA SFNIIEFPYK
NLPIEDLFNS TLVTTNITWG IQPAPMPVPV WVIILAVLAG LLLLAVLVFV MYRMGFFKRV
RPPQEEQERE QLQPHENGEG NSET


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20-783-72304 MOUSE ANTI HUMAN CD11b Azide Free - INTEGRIN ALPHA M CHAIN. MAC-1; Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11 1 mg
E1685h ELISA kit CD11 antigen-like family member B,CD11B,Cell surface glycoprotein MAC-1 subunit alpha,CR-3 alpha chain,CR3A,Homo sapiens,Human,Integrin alpha-M,ITGAM,Leukocyte adhesion receptor MO1,Neutrop 96T
U1685h CLIA CD11 antigen-like family member B,CD11B,Cell surface glycoprotein MAC-1 subunit alpha,CR-3 alpha chain,CR3A,Homo sapiens,Human,Integrin alpha-M,ITGAM,Leukocyte adhesion receptor MO1,Neutrophil ad 96T
E1685h ELISA CD11 antigen-like family member B,CD11B,Cell surface glycoprotein MAC-1 subunit alpha,CR-3 alpha chain,CR3A,Homo sapiens,Human,Integrin alpha-M,ITGAM,Leukocyte adhesion receptor MO1,Neutrophil a 96T
20-783-72302 MOUSE ANTI HUMAN CD11b RPE - INTEGRIN ALPHA M CHAIN. MAC-1; Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b antig 100 TESTS
20-783-72299 MOUSE ANTI HUMAN CD11b Biotin - INTEGRIN ALPHA M CHAIN. MAC-1; Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b an 0.1 mg
CSB-EL011877CH Chicken integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) (ITGAV) ELISA kit, Species Chicken, Sample Type serum, plasma 96T
CSB-EL011877BO Bovine integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) (ITGAV) ELISA kit, Species Bovine, Sample Type serum, plasma 96T
CSB-EL011877MO Mouse integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) (ITGAV) ELISA kit, Species Mouse, Sample Type serum, plasma 96T
CSB-EL011877HU Human integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) (ITGAV) ELISA kit, Species Human, Sample Type serum, plasma 96T
20-783-72300 MOUSE ANTI HUMAN CD11b FITC - INTEGRIN ALPHA M CHAIN. MAC-1; Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b anti 0.1 mg
U1572m CLIA CD11 antigen-like family member A,Integrin alpha-L,Itgal,Leukocyte adhesion glycoprotein LFA-1 alpha chain,Leukocyte function-associated molecule 1 alpha chain,Lfa-1,LFA-1A,Ly-15,Ly-15,Lymphocyte 96T
E1572m ELISA CD11 antigen-like family member A,Integrin alpha-L,Itgal,Leukocyte adhesion glycoprotein LFA-1 alpha chain,Leukocyte function-associated molecule 1 alpha chain,Lfa-1,LFA-1A,Ly-15,Ly-15,Lymphocyt 96T
E1572m ELISA kit CD11 antigen-like family member A,Integrin alpha-L,Itgal,Leukocyte adhesion glycoprotein LFA-1 alpha chain,Leukocyte function-associated molecule 1 alpha chain,Lfa-1,LFA-1A,Ly-15,Ly-15,Lymp 96T
E1572b ELISA kit Bos taurus,Bovine,CD11 antigen-like family member A,Integrin alpha-L,ITGAL,Leukocyte adhesion glycoprotein LFA-1 alpha chain,Leukocyte function-associated molecule 1 alpha chain,LFA-1A 96T


 

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