Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Interferon gamma (IFN-gamma)

 IFNG_RABIT              Reviewed;         167 AA.
P30123; P79215; Q0PW35;
01-APR-1993, integrated into UniProtKB/Swiss-Prot.
01-APR-1993, sequence version 1.
25-OCT-2017, entry version 120.
RecName: Full=Interferon gamma;
Short=IFN-gamma;
Flags: Precursor;
Name=IFNG;
Oryctolagus cuniculus (Rabbit).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;
Oryctolagus.
NCBI_TaxID=9986;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=B/Jas;
Yuasa T., Isono T., Tambe Y.;
"Rabbit interferon gamma.";
Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Lymph node;
Perkins H.D., Lei S., van Leeuwen B., Kerr P.J.;
"Oryctolagus cuniculus gamma interferon mRNA, complete cds.";
Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=Chinese white;
Qiao J., Meng Q., Cai X.;
"Cloning and expression of IFN gamma gene of Chinese white rabbit.";
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
[4]
NUCLEOTIDE SEQUENCE [MRNA].
Huang D., Yang G.;
"Cloning and sequence analysis of IFN-gamma gene in rabbit.";
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
[5]
NUCLEOTIDE SEQUENCE [MRNA] OF 81-136.
STRAIN=B/Jas;
PubMed=8753862; DOI=10.1007/BF02602561;
Isono T., Nagano Y., Seto A.;
"Expression of the interferon-gamma and interleukin-10 genes in rabbit
HTLV-I-transformed T-cell lines.";
Immunogenetics 44:306-308(1996).
[6]
X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS).
PubMed=1939201;
Samudzi C.T., Burton L.E., Rubin J.R.;
"Crystal structure of recombinant rabbit interferon-gamma at 2.7-A
resolution.";
J. Biol. Chem. 266:21791-21797(1991).
-!- FUNCTION: Produced by lymphocytes activated by specific antigens
or mitogens. IFN-gamma, in addition to having antiviral activity,
has important immunoregulatory functions. It is a potent activator
of macrophages, it has antiproliferative effects on transformed
cells and it can potentiate the antiviral and antitumor effects of
the type I interferons.
-!- SUBUNIT: Homodimer.
-!- SUBCELLULAR LOCATION: Secreted.
-!- TISSUE SPECIFICITY: Released primarily from activated T
lymphocytes.
-!- SIMILARITY: Belongs to the type II (or gamma) interferon family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AB010386; BAA24439.1; -; mRNA.
EMBL; AF244933; AAF64188.1; -; mRNA.
EMBL; DQ680162; ABG73601.1; -; mRNA.
EMBL; DQ852341; ABH10826.1; -; mRNA.
EMBL; D84216; BAA20884.1; -; mRNA.
RefSeq; NP_001075460.1; NM_001081991.1.
UniGene; Ocu.2149; -.
PDB; 2RIG; X-ray; 2.30 A; A=24-167.
PDBsum; 2RIG; -.
ProteinModelPortal; P30123; -.
SMR; P30123; -.
STRING; 9986.ENSOCUP00000021866; -.
Ensembl; ENSOCUT00000030109; ENSOCUP00000021866; ENSOCUG00000024937.
GeneID; 100008602; -.
KEGG; ocu:100008602; -.
CTD; 3458; -.
eggNOG; ENOG410IWSY; Eukaryota.
eggNOG; ENOG410Z8I5; LUCA.
GeneTree; ENSGT00390000007831; -.
HOGENOM; HOG000254784; -.
HOVERGEN; HBG056912; -.
InParanoid; P30123; -.
KO; K04687; -.
OMA; WKEESDK; -.
OrthoDB; EOG091G0ZH0; -.
TreeFam; TF336308; -.
EvolutionaryTrace; P30123; -.
Proteomes; UP000001811; Chromosome 4.
Bgee; ENSOCUG00000024937; -.
GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
GO; GO:0005622; C:intracellular; IEA:GOC.
GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
GO; GO:0005133; F:interferon-gamma receptor binding; IEA:InterPro.
GO; GO:0002250; P:adaptive immune response; IEA:Ensembl.
GO; GO:0019882; P:antigen processing and presentation; IEA:Ensembl.
GO; GO:0002302; P:CD8-positive, alpha-beta T cell differentiation involved in immune response; IEA:Ensembl.
GO; GO:0007050; P:cell cycle arrest; IEA:Ensembl.
GO; GO:0071351; P:cellular response to interleukin-18; IEA:Ensembl.
GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
GO; GO:0042832; P:defense response to protozoan; IEA:Ensembl.
GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IEA:Ensembl.
GO; GO:0006959; P:humoral immune response; IEA:Ensembl.
GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; IEA:Ensembl.
GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
GO; GO:0032700; P:negative regulation of interleukin-17 production; IEA:Ensembl.
GO; GO:0031642; P:negative regulation of myelination; IEA:Ensembl.
GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
GO; GO:0001781; P:neutrophil apoptotic process; IEA:Ensembl.
GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
GO; GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.
GO; GO:0060559; P:positive regulation of calcidiol 1-monooxygenase activity; IEA:Ensembl.
GO; GO:0032834; P:positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response; IEA:Ensembl.
GO; GO:0045080; P:positive regulation of chemokine biosynthetic process; IEA:Ensembl.
GO; GO:1904798; P:positive regulation of core promoter binding; IEA:Ensembl.
GO; GO:0010634; P:positive regulation of epithelial cell migration; IEA:Ensembl.
GO; GO:1903543; P:positive regulation of exosomal secretion; IEA:Ensembl.
GO; GO:0060550; P:positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity; IEA:Ensembl.
GO; GO:0060552; P:positive regulation of fructose 1,6-bisphosphate metabolic process; IEA:Ensembl.
GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IEA:Ensembl.
GO; GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IEA:Ensembl.
GO; GO:0032747; P:positive regulation of interleukin-23 production; IEA:Ensembl.
GO; GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; IEA:Ensembl.
GO; GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IEA:Ensembl.
GO; GO:0051712; P:positive regulation of killing of cells of other organism; IEA:Ensembl.
GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IEA:Ensembl.
GO; GO:0045348; P:positive regulation of MHC class II biosynthetic process; IEA:Ensembl.
GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Ensembl.
GO; GO:0045672; P:positive regulation of osteoclast differentiation; IEA:Ensembl.
GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IEA:Ensembl.
GO; GO:0031334; P:positive regulation of protein complex assembly; IEA:Ensembl.
GO; GO:0090312; P:positive regulation of protein deacetylation; IEA:Ensembl.
GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IEA:Ensembl.
GO; GO:1903078; P:positive regulation of protein localization to plasma membrane; IEA:Ensembl.
GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IEA:Ensembl.
GO; GO:0034393; P:positive regulation of smooth muscle cell apoptotic process; IEA:Ensembl.
GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
GO; GO:2000309; P:positive regulation of tumor necrosis factor (ligand) superfamily member 11 production; IEA:Ensembl.
GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
GO; GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IEA:Ensembl.
GO; GO:0000060; P:protein import into nucleus, translocation; IEA:Ensembl.
GO; GO:0050691; P:regulation of defense response to virus by host; IEA:Ensembl.
GO; GO:0050796; P:regulation of insulin secretion; IEA:Ensembl.
GO; GO:0010835; P:regulation of protein ADP-ribosylation; IEA:Ensembl.
GO; GO:0050852; P:T cell receptor signaling pathway; IEA:Ensembl.
InterPro; IPR009079; 4_helix_cytokine-like_core.
InterPro; IPR002069; Interferon_gamma.
PANTHER; PTHR11419; PTHR11419; 1.
Pfam; PF00714; IFN-gamma; 1.
PIRSF; PIRSF001936; IFN-gamma; 1.
ProDom; PD002435; Interferon_gamma; 1.
SUPFAM; SSF47266; SSF47266; 1.
1: Evidence at protein level;
3D-structure; Antiviral defense; Complete proteome; Cytokine;
Glycoprotein; Growth regulation; Pyrrolidone carboxylic acid;
Reference proteome; Secreted; Signal.
SIGNAL 1 23 {ECO:0000250}.
CHAIN 24 167 Interferon gamma.
/FTId=PRO_0000016456.
MOD_RES 24 24 Pyrrolidone carboxylic acid.
{ECO:0000250|UniProtKB:P01579}.
CARBOHYD 41 41 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 108 108 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 117 117 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CONFLICT 123 123 Missing (in Ref. 5; BAA20884).
{ECO:0000305}.
SEQUENCE 167 AA; 19516 MW; 96D1CAD2A5163850 CRC64;
MSYTSYILAF QLCLILGSYG CYCQDTLTRE TEHLKAYLKA NTSDVANGGP LFLNILRNWK
EESDNKIIQS QIVSFYFKLF DNLKDHEVIK KSMESIKEDI FVKFFNSNLT KMDDFQNLTR
ISVDDRLVQR KAVSELSNVL NFLSPKSNLK KRKRSQTLFR GRRASKY


Related products :

Catalog number Product name Quantity
18-783-78408 RABBIT ANTI HUMAN INTERFERON GAMMA Biotin - INTERFERON GAMMA; IFN-gamma Polyclonal 0.05 mg
20-663-48022 Interferon-gamma (mAHuIFNg) - Mouse Anti Human Interferon-gamma (mAHuIFNg); IFN-gamma; Immune interferon Monoclonal 1 mg
20-663-48022 Interferon-gamma (mAHuIFNg) - Mouse Anti Human Interferon-gamma (mAHuIFNg); IFN-gamma; Immune interferon Monoclonal 0.5 mg
20-271-80026 Interferon-gamma - Mouse Anti Human Interferon-gamma; IFN-gamma Monoclonal 1 mg
20-271-80026 Interferon-gamma - Mouse Anti Human Interferon-gamma; IFN-gamma Monoclonal 0.5 mg
18-783-78407 RABBIT ANTI HUMAN INTERFERON GAMMA - INTERFERON GAMMA; IFN-gamma Polyclonal 0.1 mg
20-271-80063 Interferon-gamma - Rat Anti Mouse Interferon-gamma; IFN-gamma Monoclonal 1 mg
20-663-48058 Interferon-gamma - Rat Anti-Mouse Interferon-gamma; IFN-gamma Monoclonal 0.5 mg
20-663-48058 Interferon-gamma - Rat Anti-Mouse Interferon-gamma; IFN-gamma Monoclonal 1 mg
20-271-80063 Interferon-gamma - Rat Anti Mouse Interferon-gamma; IFN-gamma Monoclonal 0.5 mg
orb82062 Human Interferon-gamma, recombinant protein Interferon gamma (IFN-gamma) Recombinant is a purified cytokine_growth factor. For research use only. 20
E0371m ELISA kit 10 kDa interferon gamma-induced protein,C7,Crg2,C-X-C motif chemokine 10,Cxcl10,Gamma-IP10,Ifi10,Inp10,Interferon-gamma induced protein CRG-2,IP-10,Mouse,Mus musculus,Scyb10,Small-inducible 96T
U0371m CLIA 10 kDa interferon gamma-induced protein,C7,Crg2,C-X-C motif chemokine 10,Cxcl10,Gamma-IP10,Ifi10,Inp10,Interferon-gamma induced protein CRG-2,IP-10,Mouse,Mus musculus,Scyb10,Small-inducible cytok 96T
E0371m ELISA 10 kDa interferon gamma-induced protein,C7,Crg2,C-X-C motif chemokine 10,Cxcl10,Gamma-IP10,Ifi10,Inp10,Interferon-gamma induced protein CRG-2,IP-10,Mouse,Mus musculus,Scyb10,Small-inducible cyto 96T
20-321-175081 GAMMA INTERFERON (IFN-gamma) - MONOCLONAL ANTIBODY TO HUMAN GAMMA INTERFERON (IFN-gamma) Monoclonal 0.1 mg
20-321-175082 GAMMA INTERFERON (IFN-gamma) - MONOCLONAL ANTIBODY TO HUMAN GAMMA INTERFERON (IFN-gamma) Monoclonal 0.3 mg
20-321-175083 GAMMA INTERFERON (IFN-gamma) - MONOCLONAL ANTIBODY TO HUMAN GAMMA INTERFERON (IFN-gamma) Monoclonal 0.1 mg
20-321-175084 GAMMA INTERFERON (IFN-gamma) - MONOCLONAL ANTIBODY TO HUMAN GAMMA INTERFERON (IFN-gamma) Monoclonal 0.3 mg
20-321-175004 GAMMA INTERFERON (IFN-gamma) - MONOCLONAL ANTIBODY TO MOUSE GAMMA INTERFERON (IFN-gamma) Monoclonal 0.1 mg
20-321-175005 GAMMA INTERFERON (IFN-gamma) - MONOCLONAL ANTIBODY TO MOUSE GAMMA INTERFERON (IFN-gamma) Monoclonal 0.5 mg
10-663-45229 Interferon-gamma (IFN-gamma) Porcine - IFN-gamma; Immune interferon N_A 0.05 mg
10-663-45229 Interferon-gamma (IFN-gamma) Porcine - IFN-gamma; Immune interferon N_A 1 mg
10-663-45229 Interferon-gamma (IFN-gamma) Porcine - IFN-gamma; Immune interferon N_A 0.01 mg
GS-1053a interferon gamma receptor 2 (interferon gamma transducer 1) primary antibody, Host: Rabbit 200ul
E0049h ELISA Homo sapiens,Human,IFNG,IFN-gamma,Immune interferon,Interferon gamma 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur