Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Interleukin-13 receptor subunit alpha-1 (IL-13 receptor subunit alpha-1) (IL-13R subunit alpha-1) (IL-13R-alpha-1) (IL-13RA1) (Cancer/testis antigen 19) (CT19) (CD antigen CD213a1)

 I13R1_HUMAN             Reviewed;         427 AA.
P78552; O95646; Q5JSL4; Q99656; Q9UDY5;
01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
01-MAY-1997, sequence version 1.
20-JUN-2018, entry version 169.
RecName: Full=Interleukin-13 receptor subunit alpha-1;
Short=IL-13 receptor subunit alpha-1;
Short=IL-13R subunit alpha-1;
Short=IL-13R-alpha-1;
Short=IL-13RA1;
AltName: Full=Cancer/testis antigen 19;
Short=CT19;
AltName: CD_antigen=CD213a1;
Flags: Precursor;
Name=IL13RA1; Synonyms=IL13R, IL13RA;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
TISSUE=Carcinoma;
PubMed=9013879; DOI=10.1016/S0014-5793(96)01462-7;
Miloux B., Laurent P., Bonnin O., Lupker J., Caput D., Vita N.,
Ferrara P.;
"Cloning of the human IL-13R alpha1 chain and reconstitution with the
IL4R alpha of a functional IL-4/IL-13 receptor complex.";
FEBS Lett. 401:163-166(1997).
[2]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
TISSUE=B-cell;
Gauchat J.-F., Schlagenhauf E., Feng N.P., Moser R., Yamage M.,
Jeannin P., Alouani S., Elson G., Notarangelo L.D., Wells T.,
Eugster H.P., Bonnefoy J.-Y.;
Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
TISSUE=T-cell;
PubMed=8910586; DOI=10.1074/jbc.271.46.29265;
Aman M.J., Tayebi N., Obiri N.I., Puri R.K., Modi W.S., Leonard W.J.;
"cDNA cloning and characterization of the human interleukin 13
receptor alpha chain.";
J. Biol. Chem. 271:29265-29270(1996).
[4]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2).
Wada M., Hisano T., Kuwano M.;
Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
TISSUE=Hippocampus;
PubMed=14702039; DOI=10.1038/ng1285;
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
"Complete sequencing and characterization of 21,243 full-length human
cDNAs.";
Nat. Genet. 36:40-45(2004).
[6]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=15772651; DOI=10.1038/nature03440;
Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A.,
Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G.,
Jones M.C., Hurles M.E., Andrews T.D., Scott C.E., Searle S.,
Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R.,
Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L.,
Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A.,
Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S.,
Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R.,
Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M.,
Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N.,
Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D.,
Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W.,
Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C.,
Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C.,
Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
Corby N., Connor R.E., David R., Davies J., Davis C., Davis J.,
Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S.,
Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I.,
Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L.,
Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P.,
Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S.,
Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A.,
Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J.,
Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J.,
Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S.,
de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z.,
Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C.,
Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W.,
Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T.,
Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I.,
Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N.,
Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J.,
Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E.,
Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S.,
Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T.,
Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S.,
Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L.,
Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A.,
Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L.,
Williams G., Williams L., Williamson A., Williamson H., Wilming L.,
Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H.,
Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A.,
Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A.,
Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T.,
Gibbs R.A., Beck S., Rogers J., Bentley D.R.;
"The DNA sequence of the human X chromosome.";
Nature 434:325-337(2005).
[7]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L.,
Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
Venter J.C.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
[8]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
TISSUE=Pancreas;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[9]
INTERACTION WITH TRAF3IP1.
PubMed=10791955; DOI=10.1074/jbc.M001095200;
Ling L., Goeddel D.V.;
"MIP-T3, a novel protein linking tumor necrosis factor receptor-
associated factor 3 to the microtubule network.";
J. Biol. Chem. 275:23852-23860(2000).
[10]
X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 29-342 IN COMPLEXES WITH IL4;
IL4RA AND IL13, DISULFIDE BONDS, AND SUBUNIT.
PubMed=18243101; DOI=10.1016/j.cell.2007.12.030;
LaPorte S.L., Juo Z.S., Vaclavikova J., Colf L.A., Qi X., Heller N.M.,
Keegan A.D., Garcia K.C.;
"Molecular and structural basis of cytokine receptor pleiotropy in the
interleukin-4/13 system.";
Cell 132:259-272(2008).
-!- FUNCTION: Binds with low affinity to interleukin-13 (IL13).
Together with IL4RA can form a functional receptor for IL13. Also
serves as an alternate accessory protein to the common cytokine
receptor gamma chain for interleukin-4 (IL4) signaling, but cannot
replace the function of IL2RG in allowing enhanced interleukin-2
(IL2) binding activity.
-!- SUBUNIT: Interleukin-13 receptor is a complex of IL4R, IL13RA1,
and possibly other components. Interacts with TRAF3IP1.
{ECO:0000269|PubMed:10791955, ECO:0000269|PubMed:18243101}.
-!- INTERACTION:
P35225:IL13; NbExp=6; IntAct=EBI-1391535, EBI-1647828;
P05112:IL4; NbExp=3; IntAct=EBI-1391535, EBI-367025;
Q8TDR0:TRAF3IP1; NbExp=3; IntAct=EBI-1391535, EBI-928811;
-!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane
protein.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=2;
Name=1;
IsoId=P78552-1; Sequence=Displayed;
Name=2;
IsoId=P78552-2; Sequence=VSP_055587, VSP_055588;
-!- TISSUE SPECIFICITY: Ubiquitous. Highest levels in heart, liver,
skeletal muscle and ovary; lowest levels in brain, lung and
kidney. Also found in B-cells, T-cells and endothelial cells.
-!- DOMAIN: The WSXWS motif appears to be necessary for proper protein
folding and thereby efficient intracellular transport and cell-
surface receptor binding.
-!- DOMAIN: The box 1 motif is required for JAK interaction and/or
activation.
-!- SIMILARITY: Belongs to the type I cytokine receptor family. Type 5
subfamily. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; Y10659; CAA71669.1; -; mRNA.
EMBL; Y09328; CAA70508.1; -; mRNA.
EMBL; U62858; AAB37127.1; -; mRNA.
EMBL; U81379; AAD00510.3; -; mRNA.
EMBL; U81380; AAD00511.2; -; mRNA.
EMBL; AK313467; BAG36253.1; -; mRNA.
EMBL; AL391280; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CH471161; EAW89893.1; -; Genomic_DNA.
EMBL; BC009960; AAH09960.1; -; mRNA.
CCDS; CCDS14573.1; -. [P78552-1]
RefSeq; NP_001551.1; NM_001560.2. [P78552-1]
UniGene; Hs.496646; -.
PDB; 3BPN; X-ray; 3.02 A; C=29-342.
PDB; 3BPO; X-ray; 3.00 A; C=29-342.
PDB; 4HWB; X-ray; 2.61 A; A=223-336.
PDB; 5E4E; X-ray; 3.00 A; C=23-340.
PDBsum; 3BPN; -.
PDBsum; 3BPO; -.
PDBsum; 4HWB; -.
PDBsum; 5E4E; -.
ProteinModelPortal; P78552; -.
SMR; P78552; -.
BioGrid; 109811; 8.
CORUM; P78552; -.
DIP; DIP-3225N; -.
IntAct; P78552; 6.
STRING; 9606.ENSP00000360730; -.
ChEMBL; CHEMBL3831285; -.
iPTMnet; P78552; -.
PhosphoSitePlus; P78552; -.
BioMuta; IL13RA1; -.
DMDM; 2494718; -.
PaxDb; P78552; -.
PeptideAtlas; P78552; -.
PRIDE; P78552; -.
ProteomicsDB; 57649; -.
DNASU; 3597; -.
Ensembl; ENST00000371642; ENSP00000360705; ENSG00000131724. [P78552-2]
Ensembl; ENST00000371666; ENSP00000360730; ENSG00000131724. [P78552-1]
GeneID; 3597; -.
KEGG; hsa:3597; -.
UCSC; uc004eqr.2; human. [P78552-1]
CTD; 3597; -.
DisGeNET; 3597; -.
EuPathDB; HostDB:ENSG00000131724.10; -.
GeneCards; IL13RA1; -.
HGNC; HGNC:5974; IL13RA1.
HPA; HPA000293; -.
MIM; 300119; gene.
neXtProt; NX_P78552; -.
OpenTargets; ENSG00000131724; -.
PharmGKB; PA200; -.
eggNOG; ENOG410IH4K; Eukaryota.
eggNOG; ENOG410YM7M; LUCA.
GeneTree; ENSGT00530000063295; -.
HOGENOM; HOG000230941; -.
HOVERGEN; HBG052060; -.
InParanoid; P78552; -.
KO; K05076; -.
OMA; ICLQVGS; -.
OrthoDB; EOG091G0FOF; -.
PhylomeDB; P78552; -.
TreeFam; TF331549; -.
Reactome; R-HSA-6785807; Interleukin-4 and 13 signaling.
SignaLink; P78552; -.
SIGNOR; P78552; -.
ChiTaRS; IL13RA1; human.
EvolutionaryTrace; P78552; -.
GeneWiki; Interleukin_13_receptor,_alpha_1; -.
GenomeRNAi; 3597; -.
PRO; PR:P78552; -.
Proteomes; UP000005640; Chromosome X.
Bgee; ENSG00000131724; -.
CleanEx; HS_IL13RA1; -.
Genevisible; P78552; HS.
GO; GO:0005898; C:interleukin-13 receptor complex; TAS:ProtInc.
GO; GO:0005886; C:plasma membrane; TAS:Reactome.
GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
CDD; cd00063; FN3; 1.
Gene3D; 2.60.40.10; -; 3.
InterPro; IPR003961; FN3_dom.
InterPro; IPR036116; FN3_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003532; Short_hematopoietin_rcpt_2_CS.
InterPro; IPR015321; TypeI_recpt_CBD.
Pfam; PF09240; IL6Ra-bind; 1.
SUPFAM; SSF49265; SSF49265; 2.
PROSITE; PS50853; FN3; 3.
PROSITE; PS01356; HEMATOPO_REC_S_F2; 1.
1: Evidence at protein level;
3D-structure; Alternative splicing; Complete proteome; Disulfide bond;
Glycoprotein; Membrane; Receptor; Reference proteome; Repeat; Signal;
Transmembrane; Transmembrane helix.
SIGNAL 1 21 {ECO:0000255}.
CHAIN 22 427 Interleukin-13 receptor subunit alpha-1.
/FTId=PRO_0000010939.
TOPO_DOM 22 343 Extracellular. {ECO:0000255}.
TRANSMEM 344 367 Helical. {ECO:0000255}.
TOPO_DOM 368 427 Cytoplasmic. {ECO:0000255}.
DOMAIN 34 123 Fibronectin type-III 1.
{ECO:0000255|PROSITE-ProRule:PRU00316}.
DOMAIN 128 226 Fibronectin type-III 2.
{ECO:0000255|PROSITE-ProRule:PRU00316}.
DOMAIN 227 339 Fibronectin type-III 3.
{ECO:0000255|PROSITE-ProRule:PRU00316}.
MOTIF 327 331 WSXWS motif.
MOTIF 374 382 Box 1 motif.
CARBOHYD 37 37 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 61 61 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 105 105 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 138 138 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 157 157 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 235 235 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 265 265 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 293 293 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 329 329 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 341 341 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 62 102 {ECO:0000269|PubMed:18243101}.
DISULFID 95 117 {ECO:0000269|PubMed:18243101}.
DISULFID 134 144 {ECO:0000269|PubMed:18243101}.
DISULFID 173 185 {ECO:0000269|PubMed:18243101}.
DISULFID 257 320 {ECO:0000269|PubMed:18243101}.
DISULFID 282 296 {ECO:0000269|PubMed:18243101}.
VAR_SEQ 278 279 QE -> RF (in isoform 2).
{ECO:0000303|Ref.4}.
/FTId=VSP_055587.
VAR_SEQ 280 427 Missing (in isoform 2).
{ECO:0000303|Ref.4}.
/FTId=VSP_055588.
CONFLICT 130 130 T -> I (in Ref. 3; AAB37127).
{ECO:0000305}.
CONFLICT 358 358 G -> D (in Ref. 3; AAB37127).
{ECO:0000305}.
STRAND 36 43 {ECO:0000244|PDB:3BPO}.
TURN 44 46 {ECO:0000244|PDB:3BPO}.
STRAND 47 53 {ECO:0000244|PDB:3BPO}.
STRAND 66 68 {ECO:0000244|PDB:3BPO}.
TURN 71 73 {ECO:0000244|PDB:5E4E}.
STRAND 77 87 {ECO:0000244|PDB:3BPO}.
STRAND 90 92 {ECO:0000244|PDB:5E4E}.
STRAND 94 100 {ECO:0000244|PDB:3BPO}.
STRAND 114 118 {ECO:0000244|PDB:3BPO}.
TURN 125 127 {ECO:0000244|PDB:3BPN}.
STRAND 130 137 {ECO:0000244|PDB:3BPO}.
TURN 138 140 {ECO:0000244|PDB:3BPO}.
STRAND 141 147 {ECO:0000244|PDB:3BPO}.
STRAND 158 166 {ECO:0000244|PDB:3BPO}.
STRAND 171 173 {ECO:0000244|PDB:5E4E}.
STRAND 176 179 {ECO:0000244|PDB:3BPO}.
STRAND 182 188 {ECO:0000244|PDB:3BPO}.
STRAND 202 208 {ECO:0000244|PDB:3BPO}.
STRAND 216 220 {ECO:0000244|PDB:3BPO}.
STRAND 222 227 {ECO:0000244|PDB:3BPO}.
STRAND 232 239 {ECO:0000244|PDB:4HWB}.
STRAND 242 248 {ECO:0000244|PDB:4HWB}.
HELIX 252 255 {ECO:0000244|PDB:4HWB}.
STRAND 258 265 {ECO:0000244|PDB:4HWB}.
STRAND 267 269 {ECO:0000244|PDB:4HWB}.
STRAND 273 278 {ECO:0000244|PDB:4HWB}.
STRAND 285 288 {ECO:0000244|PDB:4HWB}.
STRAND 292 299 {ECO:0000244|PDB:3BPO}.
STRAND 309 316 {ECO:0000244|PDB:4HWB}.
HELIX 318 320 {ECO:0000244|PDB:4HWB}.
STRAND 334 337 {ECO:0000244|PDB:3BPO}.
SEQUENCE 427 AA; 48760 MW; 5983B3E8F554107B CRC64;
MEWPARLCGL WALLLCAGGG GGGGGAAPTE TQPPVTNLSV SVENLCTVIW TWNPPEGASS
NCSLWYFSHF GDKQDKKIAP ETRRSIEVPL NERICLQVGS QCSTNESEKP SILVEKCISP
PEGDPESAVT ELQCIWHNLS YMKCSWLPGR NTSPDTNYTL YYWHRSLEKI HQCENIFREG
QYFGCSFDLT KVKDSSFEQH SVQIMVKDNA GKIKPSFNIV PLTSRVKPDP PHIKNLSFHN
DDLYVQWENP QNFISRCLFY EVEVNNSQTE THNVFYVQEA KCENPEFERN VENTSCFMVP
GVLPDTLNTV RIRVKTNKLC YEDDKLWSNW SQEMSIGKKR NSTLYITMLL IVPVIVAGAI
IVLLLYLKRL KIIIFPPIPD PGKIFKEMFG DQNDDTLHWK KYDIYEKQTK EETDSVVLIE
NLKKASQ


Related products :

Catalog number Product name Quantity
U0229h CLIA Homo sapiens,Human,IL-2 receptor subunit alpha,IL-2R subunit alpha,IL2RA,IL-2-RA,IL2-RA,Interleukin-2 receptor subunit alpha,p55,TAC antigen 96T
E0229h ELISA kit Homo sapiens,Human,IL-2 receptor subunit alpha,IL-2R subunit alpha,IL2RA,IL-2-RA,IL2-RA,Interleukin-2 receptor subunit alpha,p55,TAC antigen 96T
E0229h ELISA Homo sapiens,Human,IL-2 receptor subunit alpha,IL-2R subunit alpha,IL2RA,IL-2-RA,IL2-RA,Interleukin-2 receptor subunit alpha,p55,TAC antigen 96T
E0229b ELISA kit Bos taurus,Bovine,IL-2 receptor subunit alpha,IL-2R subunit alpha,IL2RA,IL-2-RA,IL2-RA,Interleukin-2 receptor subunit alpha,p55,TAC antigen 96T
U0229b CLIA Bos taurus,Bovine,IL-2 receptor subunit alpha,IL-2R subunit alpha,IL2RA,IL-2-RA,IL2-RA,Interleukin-2 receptor subunit alpha,p55,TAC antigen 96T
E0229b ELISA Bos taurus,Bovine,IL-2 receptor subunit alpha,IL-2R subunit alpha,IL2RA,IL-2-RA,IL2-RA,Interleukin-2 receptor subunit alpha,p55,TAC antigen 96T
U1815h CLIA kit gp80,Homo sapiens,Human,IL-6 receptor subunit alpha,IL6R,IL-6R 1,IL-6R subunit alpha,IL-6RA,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Membrane glycoprotein 80 96T
E1815h ELISA kit gp80,Homo sapiens,Human,IL-6 receptor subunit alpha,IL6R,IL-6R 1,IL-6R subunit alpha,IL-6RA,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Membrane glycoprotein 80 96T
U1815h CLIA gp80,Homo sapiens,Human,IL-6 receptor subunit alpha,IL6R,IL-6R 1,IL-6R subunit alpha,IL-6RA,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Membrane glycoprotein 80 96T
E1815h ELISA gp80,Homo sapiens,Human,IL-6 receptor subunit alpha,IL6R,IL-6R 1,IL-6R subunit alpha,IL-6RA,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Membrane glycoprotein 80 96T
U2031h CLIA 582J2.1,Homo sapiens,Human,IL-4 receptor subunit alpha,IL4R,IL-4R subunit alpha,IL4RA,IL-4RA,IL-4R-alpha,Interleukin-4 receptor subunit alpha 96T
E2031h ELISA kit 582J2.1,Homo sapiens,Human,IL-4 receptor subunit alpha,IL4R,IL-4R subunit alpha,IL4RA,IL-4RA,IL-4R-alpha,Interleukin-4 receptor subunit alpha 96T
U2031h CLIA kit 582J2.1,Homo sapiens,Human,IL-4 receptor subunit alpha,IL4R,IL-4R subunit alpha,IL4RA,IL-4RA,IL-4R-alpha,Interleukin-4 receptor subunit alpha 96T
E2031h ELISA 582J2.1,Homo sapiens,Human,IL-4 receptor subunit alpha,IL4R,IL-4R subunit alpha,IL4RA,IL-4RA,IL-4R-alpha,Interleukin-4 receptor subunit alpha 96T
E1815m ELISA IL-6 receptor subunit alpha,Il6r,IL-6R 1,IL-6R subunit alpha,Il6ra,IL-6RA,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Mouse,Mus musculus 96T
E1815r ELISA kit IL-6 receptor subunit alpha,Il6r,IL-6R 1,IL-6R subunit alpha,Il6ra,IL-6RA,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Rat,Rattus norvegicus 96T
E1815r ELISA IL-6 receptor subunit alpha,Il6r,IL-6R 1,IL-6R subunit alpha,Il6ra,IL-6RA,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Rat,Rattus norvegicus 96T
U1815m CLIA IL-6 receptor subunit alpha,Il6r,IL-6R 1,IL-6R subunit alpha,Il6ra,IL-6RA,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Mouse,Mus musculus 96T
U2031r CLIA kit IL-4 receptor subunit alpha,Il4r,IL-4R subunit alpha,Il4ra,IL-4RA,IL-4R-alpha,Interleukin-4 receptor subunit alpha,Rat,Rattus norvegicus 96T
U1815m CLIA kit IL-6 receptor subunit alpha,Il6r,IL-6R 1,IL-6R subunit alpha,Il6ra,IL-6RA,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Mouse,Mus musculus 96T
U1815r CLIA IL-6 receptor subunit alpha,Il6r,IL-6R 1,IL-6R subunit alpha,Il6ra,IL-6RA,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Rat,Rattus norvegicus 96T
U2031m CLIA kit IL-4 receptor subunit alpha,Il4r,IL-4R subunit alpha,Il4ra,IL-4RA,IL-4R-alpha,Interleukin-4 receptor subunit alpha,Mouse,Mus musculus 96T
E1815m ELISA kit IL-6 receptor subunit alpha,Il6r,IL-6R 1,IL-6R subunit alpha,Il6ra,IL-6RA,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Mouse,Mus musculus 96T
E2031m ELISA IL-4 receptor subunit alpha,Il4r,IL-4R subunit alpha,Il4ra,IL-4RA,IL-4R-alpha,Interleukin-4 receptor subunit alpha,Mouse,Mus musculus 96T
U1815r CLIA kit IL-6 receptor subunit alpha,Il6r,IL-6R 1,IL-6R subunit alpha,Il6ra,IL-6RA,IL-6R-alpha,Interleukin-6 receptor subunit alpha,Rat,Rattus norvegicus 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur