Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Interleukin-18 receptor accessory protein (IL-18 receptor accessory protein) (IL-18RAcP) (Accessory protein-like) (AcPL) (CD218 antigen-like family member B) (CDw218b) (IL-1R accessory protein-like) (IL-1RAcPL) (Interleukin-1 receptor 7) (IL-1R-7) (IL-1R7) (Interleukin-18 receptor accessory protein-like) (Interleukin-18 receptor beta) (IL-18R-beta) (IL-18Rbeta) (CD antigen CD218b)

 I18RA_HUMAN             Reviewed;         599 AA.
O95256; B2RPJ3; Q2QDE5; Q3KPE7; Q3KPE8; Q53TT4; Q53TU5;
27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
01-MAY-1999, sequence version 1.
12-SEP-2018, entry version 157.
RecName: Full=Interleukin-18 receptor accessory protein;
Short=IL-18 receptor accessory protein;
Short=IL-18RAcP;
AltName: Full=Accessory protein-like;
Short=AcPL;
AltName: Full=CD218 antigen-like family member B;
AltName: Full=CDw218b;
AltName: Full=IL-1R accessory protein-like {ECO:0000303|PubMed:10653850};
Short=IL-1RAcPL;
AltName: Full=Interleukin-1 receptor 7;
Short=IL-1R-7;
Short=IL-1R7;
AltName: Full=Interleukin-18 receptor accessory protein-like;
AltName: Full=Interleukin-18 receptor beta {ECO:0000303|PubMed:10653850, ECO:0000303|PubMed:14528293, ECO:0000303|PubMed:25500532};
Short=IL-18R-beta;
Short=IL-18Rbeta {ECO:0000303|PubMed:10653850, ECO:0000303|PubMed:14528293, ECO:0000303|PubMed:25500532};
AltName: CD_antigen=CD218b;
Flags: Precursor;
Name=IL18RAP {ECO:0000312|HGNC:HGNC:5989}; Synonyms=IL1R7;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, SUBUNIT, AND TISSUE
SPECIFICITY.
PubMed=9792649; DOI=10.1074/jbc.273.45.29445;
Born T.L., Thomassen E., Bird T.A., Sims J.E.;
"Cloning of a novel receptor subunit, AcPL, required for interleukin-
18 signaling.";
J. Biol. Chem. 273:29445-29450(1998).
[2]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4), AND TISSUE SPECIFICITY.
PubMed=17897836; DOI=10.1016/j.cyto.2007.07.186;
Fiszer D., Rozwadowska N., Rychlewski L., Kosicki W., Kurpisz M.;
"Identification of IL-18RAP mRNA truncated splice variants in human
testis and the other human tissues.";
Cytokine 39:178-183(2007).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=15815621; DOI=10.1038/nature03466;
Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
Waterston R.H., Wilson R.K.;
"Generation and annotation of the DNA sequences of human chromosomes 2
and 4.";
Nature 434:724-731(2005).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
Venter J.C.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
"NEDO human cDNA sequencing project focused on splicing variants.";
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
[6]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
TISSUE=Brain;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[7]
FUNCTION, AND TISSUE SPECIFICITY.
PubMed=10653850;
Tominaga K., Yoshimoto T., Torigoe K., Kurimoto M., Matsui K.,
Hada T., Okamura H., Nakanishi K.;
"IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from
human T cells.";
Int. Immunol. 12:151-160(2000).
[8]
TISSUE SPECIFICITY, AND INDUCTION BY IFN-ALPHA AND
IL12/INTERLEUKIN-12.
PubMed=10925275; DOI=10.4049/jimmunol.165.4.1933;
Sareneva T., Julkunen I., Matikainen S.;
"IFN-alpha and IL-12 induce IL-18 receptor gene expression in human NK
and T cells.";
J. Immunol. 165:1933-1938(2000).
[9]
TISSUE SPECIFICITY.
PubMed=11046021; DOI=10.4049/jimmunol.165.9.4950;
Debets R., Timans J.C., Churakowa T., Zurawski S., de Waal Malefyt R.,
Moore K.W., Abrams J.S., O'Garra A., Bazan J.F., Kastelein R.A.;
"IL-18 receptors, their role in ligand binding and function: anti-IL-
1RAcPL antibody, a potent antagonist of IL-18.";
J. Immunol. 165:4950-4956(2000).
[10]
FUNCTION, SUBUNIT, AND SUBCELLULAR LOCATION.
PubMed=14528293; DOI=10.1038/nsb993;
Kato Z., Jee J., Shikano H., Mishima M., Ohki I., Ohnishi H., Li A.,
Hashimoto K., Matsukuma E., Omoya K., Yamamoto Y., Yoneda T., Hara T.,
Kondo N., Shirakawa M.;
"The structure and binding mode of interleukin-18.";
Nat. Struct. Biol. 10:966-971(2003).
[11]
X-RAY CRYSTALLOGRAPHY (3.10 ANGSTROMS) OF 15-356, GLYCOSYLATION AT
ASN-119; ASN-152 AND ASN-345, DISULFIDE BONDS, MUTAGENESIS OF LEU-167;
GLU-210; TYR-212; TYR-214; LYS-313 AND 15-GLU--PRO-176, SUBUNIT, AND
FUNCTION.
PubMed=25500532; DOI=10.1038/ncomms6340;
Tsutsumi N., Kimura T., Arita K., Ariyoshi M., Ohnishi H.,
Yamamoto T., Zuo X., Maenaka K., Park E.Y., Kondo N., Shirakawa M.,
Tochio H., Kato Z.;
"The structural basis for receptor recognition of human interleukin-
18.";
Nat. Commun. 5:5340-5340(2014).
-!- FUNCTION: Within the IL18 receptor complex, does not mediate IL18-
binding, but involved in IL18-dependent signal transduction,
leading to NF-kappa-B and JNK activation (PubMed:9792649,
PubMed:14528293, PubMed:25500532). May play a role in IL18-
mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).
{ECO:0000269|PubMed:14528293, ECO:0000269|PubMed:25500532,
ECO:0000269|PubMed:9792649, ECO:0000305|PubMed:10653850}.
-!- SUBUNIT: Forms a ternary complex with IL18 and IL18R1
(PubMed:14528293, PubMed:25500532). Within this complex, IL18R1 is
involved in ligand-binding and IL18RAP in signaling leading to NF-
kappa-B and JNK activation (Probable).
{ECO:0000269|PubMed:14528293, ECO:0000269|PubMed:25500532,
ECO:0000305}.
-!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:14528293};
Single-pass type I membrane protein {ECO:0000305}.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=4;
Name=1;
IsoId=O95256-1; Sequence=Displayed;
Name=2;
IsoId=O95256-2; Sequence=VSP_056295;
Note=No experimental confirmation available.;
Name=3; Synonyms=IL-18RAPshort {ECO:0000303|PubMed:17897836};
IsoId=O95256-3; Sequence=VSP_059116, VSP_059117;
Name=4;
IsoId=O95256-4; Sequence=VSP_059114, VSP_059115;
-!- TISSUE SPECIFICITY: Detected in adrenal gland, bone marrow, brain,
fetal brain, fetal liver, heart, kidney, lung, liver, peripheral
blood leukocytes, placenta, prostate, salivary gland, skeletal
muscle, spinal cord, testis, thymus, thyroid, trachea and uterus
(PubMed:17897836). Strongly expressed in peripheral blood
leukocytes and spleen and, to a lesser extent, in colon
(PubMed:9792649). Specifically coexpressed with IL18R1 in T-helper
1 (Th1)cells (PubMed:10925275, PubMed:11046021, PubMed:10653850).
{ECO:0000269|PubMed:10653850, ECO:0000269|PubMed:10925275,
ECO:0000269|PubMed:11046021, ECO:0000269|PubMed:17897836,
ECO:0000269|PubMed:9792649}.
-!- INDUCTION: Induced by IFN-alpha and IL12/interleukin-12 in natural
killer (NK) cells and T-cells. {ECO:0000269|PubMed:10925275}.
-!- PTM: N-glycosylated. {ECO:0000269|PubMed:25500532}.
-!- SIMILARITY: Belongs to the interleukin-1 receptor family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AF077346; AAC72196.1; -; mRNA.
EMBL; DQ116957; AAZ52551.1; -; mRNA.
EMBL; AC007278; AAY15080.1; -; Genomic_DNA.
EMBL; AC007248; AAY15049.1; -; Genomic_DNA.
EMBL; CH471127; EAX01791.1; -; Genomic_DNA.
EMBL; AK300026; BAG61837.1; -; mRNA.
EMBL; BC069630; AAH69630.1; -; mRNA.
EMBL; BC106764; AAI06765.1; -; mRNA.
EMBL; BC106765; AAI06766.1; -; mRNA.
EMBL; BC137474; AAI37475.1; -; mRNA.
EMBL; BC137475; AAI37476.1; -; mRNA.
CCDS; CCDS2061.1; -. [O95256-1]
RefSeq; NP_003844.1; NM_003853.3. [O95256-1]
RefSeq; XP_011510389.1; XM_011512087.2. [O95256-2]
RefSeq; XP_011510390.1; XM_011512088.2. [O95256-2]
UniGene; Hs.158315; -.
PDB; 3WO4; X-ray; 3.10 A; C=15-356.
PDBsum; 3WO4; -.
ProteinModelPortal; O95256; -.
SMR; O95256; -.
BioGrid; 114335; 3.
STRING; 9606.ENSP00000264260; -.
iPTMnet; O95256; -.
PhosphoSitePlus; O95256; -.
BioMuta; IL18RAP; -.
PaxDb; O95256; -.
PeptideAtlas; O95256; -.
PRIDE; O95256; -.
ProteomicsDB; 50750; -.
Ensembl; ENST00000264260; ENSP00000264260; ENSG00000115607. [O95256-1]
Ensembl; ENST00000409369; ENSP00000387201; ENSG00000115607. [O95256-2]
GeneID; 8807; -.
KEGG; hsa:8807; -.
UCSC; uc002tbx.4; human. [O95256-1]
CTD; 8807; -.
DisGeNET; 8807; -.
EuPathDB; HostDB:ENSG00000115607.9; -.
GeneCards; IL18RAP; -.
HGNC; HGNC:5989; IL18RAP.
HPA; CAB025270; -.
MIM; 604509; gene.
neXtProt; NX_O95256; -.
OpenTargets; ENSG00000115607; -.
PharmGKB; PA29805; -.
eggNOG; ENOG410IGUG; Eukaryota.
eggNOG; ENOG410Y9SN; LUCA.
GeneTree; ENSGT00760000119071; -.
HOGENOM; HOG000060101; -.
HOVERGEN; HBG081778; -.
InParanoid; O95256; -.
KO; K05174; -.
OMA; YVCDYTQ; -.
OrthoDB; EOG091G0GXW; -.
PhylomeDB; O95256; -.
TreeFam; TF325519; -.
Reactome; R-HSA-9012546; Interleukin-18 signaling.
GeneWiki; IL18RAP; -.
GenomeRNAi; 8807; -.
PRO; PR:O95256; -.
Proteomes; UP000005640; Chromosome 2.
Bgee; ENSG00000115607; Expressed in 112 organ(s), highest expression level in bone marrow.
CleanEx; HS_IL18RAP; -.
ExpressionAtlas; O95256; baseline and differential.
Genevisible; O95256; HS.
GO; GO:0045092; C:interleukin-18 receptor complex; IDA:UniProtKB.
GO; GO:0005886; C:plasma membrane; TAS:Reactome.
GO; GO:0042008; F:interleukin-18 receptor activity; IDA:UniProtKB.
GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
GO; GO:0006955; P:immune response; TAS:ProtInc.
GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
GO; GO:0032609; P:interferon-gamma production; IEA:Ensembl.
GO; GO:0035655; P:interleukin-18-mediated signaling pathway; IDA:UniProtKB.
GO; GO:0032635; P:interleukin-6 production; IEA:Ensembl.
GO; GO:0042119; P:neutrophil activation; IEA:Ensembl.
GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IEA:Ensembl.
GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
GO; GO:0035744; P:T-helper 1 cell cytokine production; IEA:Ensembl.
Gene3D; 2.60.40.10; -; 2.
Gene3D; 3.40.50.10140; -; 1.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003599; Ig_sub.
InterPro; IPR015621; IL-1_rcpt_fam.
InterPro; IPR000157; TIR_dom.
InterPro; IPR035897; Toll_tir_struct_dom_sf.
PANTHER; PTHR11890; PTHR11890; 1.
Pfam; PF13895; Ig_2; 1.
Pfam; PF01582; TIR; 1.
SMART; SM00409; IG; 2.
SMART; SM00255; TIR; 1.
SUPFAM; SSF48726; SSF48726; 2.
SUPFAM; SSF52200; SSF52200; 1.
PROSITE; PS50835; IG_LIKE; 2.
PROSITE; PS50104; TIR; 1.
1: Evidence at protein level;
3D-structure; Alternative splicing; Cell membrane; Complete proteome;
Disulfide bond; Glycoprotein; Immunoglobulin domain;
Inflammatory response; Membrane; Polymorphism; Receptor;
Reference proteome; Repeat; Signal; Transmembrane;
Transmembrane helix.
SIGNAL 1 19 {ECO:0000255}.
CHAIN 20 599 Interleukin-18 receptor accessory
protein.
/FTId=PRO_0000042185.
TOPO_DOM 20 356 Extracellular. {ECO:0000255}.
TRANSMEM 357 377 Helical. {ECO:0000255}.
TOPO_DOM 378 599 Cytoplasmic. {ECO:0000255}.
DOMAIN 149 235 Ig-like C2-type 1.
DOMAIN 251 353 Ig-like C2-type 2.
DOMAIN 406 562 TIR. {ECO:0000255|PROSITE-
ProRule:PRU00204}.
CARBOHYD 21 21 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 119 119 N-linked (GlcNAc...) asparagine.
{ECO:0000244|PDB:3WO4,
ECO:0000269|PubMed:25500532}.
CARBOHYD 152 152 N-linked (GlcNAc...) asparagine.
{ECO:0000244|PDB:3WO4,
ECO:0000269|PubMed:25500532}.
CARBOHYD 345 345 N-linked (GlcNAc...) asparagine.
{ECO:0000244|PDB:3WO4,
ECO:0000269|PubMed:25500532}.
DISULFID 46 126 {ECO:0000244|PDB:3WO4,
ECO:0000269|PubMed:25500532}.
DISULFID 155 180 {ECO:0000244|PDB:3WO4,
ECO:0000269|PubMed:25500532}.
DISULFID 175 221 {ECO:0000244|PDB:3WO4,
ECO:0000269|PubMed:25500532}.
DISULFID 180 221 {ECO:0000255|PROSITE-ProRule:PRU00114}.
DISULFID 273 337 {ECO:0000244|PDB:3WO4,
ECO:0000255|PROSITE-ProRule:PRU00114,
ECO:0000269|PubMed:25500532}.
VAR_SEQ 1 142 Missing (in isoform 2).
{ECO:0000303|PubMed:15489334}.
/FTId=VSP_056295.
VAR_SEQ 118 126 VNNSGSYIC -> LGHIFVDPR (in isoform 4).
{ECO:0000269|PubMed:17897836}.
/FTId=VSP_059114.
VAR_SEQ 127 599 Missing (in isoform 4).
{ECO:0000269|PubMed:17897836}.
/FTId=VSP_059115.
VAR_SEQ 133 149 SPYDVACCVKMILEVKP -> YDPNTFLSENISKSSII
(in isoform 3).
{ECO:0000269|PubMed:17897836}.
/FTId=VSP_059116.
VAR_SEQ 150 599 Missing (in isoform 3).
{ECO:0000269|PubMed:17897836}.
/FTId=VSP_059117.
VARIANT 350 350 V -> I (in dbSNP:rs11465716).
/FTId=VAR_034005.
MUTAGEN 15 176 Missing: Impairs IL18 receptor signaling
via NF-kappa-B.
{ECO:0000269|PubMed:25500532}.
MUTAGEN 167 167 L->A: Decreases binding to the preformed
binary complex of IL18 and IL18R1.
{ECO:0000269|PubMed:25500532}.
MUTAGEN 210 210 E->A: Decreases binding to the preformed
binary complex of IL18 and IL18R1.
Impairs IL18 receptor signaling via NF-
kappa-B; when associated with A-212 and
A-214. {ECO:0000269|PubMed:25500532}.
MUTAGEN 212 212 Y->A: Abolishes binding to the preformed
binary complex of IL18 and IL18R1.
Impairs IL18 receptor signaling via NF-
kappa-B; when associated with A-210 and
A-214. {ECO:0000269|PubMed:25500532}.
MUTAGEN 214 214 Y->A: Decreases binding to the preformed
binary complex of IL18 and IL18R1.
Impairs IL18 receptor signaling via NF-
kappa-B; when associated with A-210 and
A-212. {ECO:0000269|PubMed:25500532}.
MUTAGEN 313 313 K->A: Decreases binding to the preformed
binary complex of IL18 and IL18R1.
Decreases IL18 receptor signaling via NF-
kappa-B. {ECO:0000269|PubMed:25500532}.
STRAND 32 36 {ECO:0000244|PDB:3WO4}.
STRAND 41 44 {ECO:0000244|PDB:3WO4}.
STRAND 110 115 {ECO:0000244|PDB:3WO4}.
STRAND 117 120 {ECO:0000244|PDB:3WO4}.
STRAND 122 126 {ECO:0000244|PDB:3WO4}.
STRAND 141 149 {ECO:0000244|PDB:3WO4}.
STRAND 154 157 {ECO:0000244|PDB:3WO4}.
STRAND 161 166 {ECO:0000244|PDB:3WO4}.
STRAND 171 174 {ECO:0000244|PDB:3WO4}.
HELIX 176 178 {ECO:0000244|PDB:3WO4}.
TURN 180 183 {ECO:0000244|PDB:3WO4}.
STRAND 189 193 {ECO:0000244|PDB:3WO4}.
STRAND 203 210 {ECO:0000244|PDB:3WO4}.
HELIX 213 215 {ECO:0000244|PDB:3WO4}.
STRAND 217 224 {ECO:0000244|PDB:3WO4}.
STRAND 233 243 {ECO:0000244|PDB:3WO4}.
STRAND 252 255 {ECO:0000244|PDB:3WO4}.
STRAND 258 263 {ECO:0000244|PDB:3WO4}.
STRAND 269 278 {ECO:0000244|PDB:3WO4}.
STRAND 286 293 {ECO:0000244|PDB:3WO4}.
STRAND 296 299 {ECO:0000244|PDB:3WO4}.
STRAND 306 310 {ECO:0000244|PDB:3WO4}.
STRAND 312 325 {ECO:0000244|PDB:3WO4}.
HELIX 328 331 {ECO:0000244|PDB:3WO4}.
STRAND 333 341 {ECO:0000244|PDB:3WO4}.
STRAND 344 354 {ECO:0000244|PDB:3WO4}.
SEQUENCE 599 AA; 68310 MW; 54807DA3E05462F1 CRC64;
MLCLGWIFLW LVAGERIKGF NISGCSTKKL LWTYSTRSEE EFVLFCDLPE PQKSHFCHRN
RLSPKQVPEH LPFMGSNDLS DVQWYQQPSN GDPLEDIRKS YPHIIQDKCT LHFLTPGVNN
SGSYICRPKM IKSPYDVACC VKMILEVKPQ TNASCEYSAS HKQDLLLGST GSISCPSLSC
QSDAQSPAVT WYKNGKLLSV ERSNRIVVDE VYDYHQGTYV CDYTQSDTVS SWTVRAVVQV
RTIVGDTKLK PDILDPVEDT LEVELGKPLT ISCKARFGFE RVFNPVIKWY IKDSDLEWEV
SVPEAKSIKS TLKDEIIERN IILEKVTQRD LRRKFVCFVQ NSIGNTTQSV QLKEKRGVVL
LYILLGTIGT LVAVLAASAL LYRHWIEIVL LYRTYQSKDQ TLGDKKDFDA FVSYAKWSSF
PSEATSSLSE EHLALSLFPD VLENKYGYSL CLLERDVAPG GVYAEDIVSI IKRSRRGIFI
LSPNYVNGPS IFELQAAVNL ALDDQTLKLI LIKFCYFQEP ESLPHLVKKA LRVLPTVTWR
GLKSVPPNSR FWAKMRYHMP VKNSQGFTWN QLRITSRIFQ WKGLSRTETT GRSSQPKEW


Related products :

Catalog number Product name Quantity
26-207 IL1RAPL2 is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins, and is most closely related to interleukin 1 receptor accessory protein-like 0.05 mg
CB73 Interleukin-18 receptor accessory protein IL18RAP (C-His tag) lmg
C477 Interleukin-1 Receptor Accessory Protein IL-1RAcP lmg
CC35 Interleukin-18 receptor accessory protein IL18RAP (C-Fc-His tag) lmg
E9331h Human Interleukin 18 Receptor Accessory Protein EL 96T
CC35 Interleukin-18 receptor accessory protein IL18RAP (C-Fc-His tag) 500
CB73 Interleukin-18 receptor accessory protein IL18RAP (C-His tag) 500
IRPL1_RAT Rat ELISA Kit FOR Interleukin-1 receptor accessory protein-like 1 96T
C477 Interleukin-1 Receptor Accessory Protein IL-1RAcP 500
IL1RAPL2 IL1RAP Gene interleukin 1 receptor accessory protein
E91655Hu ELISA Kit for Interleukin 18 Receptor Accessory Protein (IL18RAP) 96T/Kit
201-20-2761 IL1RAPL1{interleukin 1 receptor accessory protein-like 1}rabbit.pAb 0.2ml
CD72 Human Interleukin-18 receptor accessory protein IL18RAP (C-Fc-His tag) 50
CSB-EL011623RA Rat Interleukin-1 receptor accessory protein(IL1RAP) ELISA kit 96T
CC08 Human Interleukin-1 Receptor Accessory Protein IL-1RAcP 50
IL1RL2 IL1RAPL2 Gene interleukin 1 receptor accessory protein-like 2
E97819Hu ELISA Kit for Interleukin 1 Receptor Accessory Protein (IL1RAP) 96T/Kit
IL1RL1 IL1RAPL1 Gene interleukin 1 receptor accessory protein-like 1
C033 Human Interleukin-1 Receptor Accessory Protein IL-1RAcP l0
CB99 Human Interleukin-18 receptor accessory protein IL18RAP (C-His tag) 50
E97819Mu ELISA Kit for Interleukin 1 Receptor Accessory Protein (IL1RAP) 96T/Kit
CC35 Human Interleukin-18 receptor accessory protein IL18RAP (C-His tag) l0
IL1A IL18RAP Gene interleukin 18 receptor accessory protein
CB99 Human Interleukin-18 receptor accessory protein IL18RAP (C-Fc-His tag) l0
CSB-EL011624RA Rat Interleukin-1 receptor accessory protein-like 1(IL1RAPL1) ELISA kit 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur