Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)

 Q7DLX9_TOBAC            Unreviewed;       470 AA.
Q7DLX9;
05-JUL-2004, integrated into UniProtKB/TrEMBL.
05-JUL-2004, sequence version 1.
12-SEP-2018, entry version 73.
RecName: Full=Isocitrate dehydrogenase [NADP] {ECO:0000256|PIRNR:PIRNR000108};
EC=1.1.1.42 {ECO:0000256|PIRNR:PIRNR000108};
Nicotiana tabacum (Common tobacco).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; asterids; lamiids; Solanales; Solanaceae;
Nicotianoideae; Nicotianeae; Nicotiana.
NCBI_TaxID=4097 {ECO:0000313|EMBL:CAA65504.1};
[1] {ECO:0000313|EMBL:CAA65504.1}
NUCLEOTIDE SEQUENCE.
PubMed=9636233; DOI=10.1073/pnas.95.13.7813;
Galvez S., Roche O., Bismuth E., Brown S., Gadal P., Hodges M.;
"Mitochondrial localization of a NADP-dependent [corrected] isocitrate
dehydrogenase isoenzyme by using the green fluorescent protein as a
marker.";
Proc. Natl. Acad. Sci. U.S.A. 95:7813-7818(1998).
-!- CATALYTIC ACTIVITY: Isocitrate + NADP(+) = 2-oxoglutarate + CO(2)
+ NADPH. {ECO:0000256|PIRNR:PIRNR000108}.
-!- COFACTOR:
Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
Evidence={ECO:0000256|PIRNR:PIRNR000108};
Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
Evidence={ECO:0000256|PIRNR:PIRNR000108};
Note=Binds 1 Mg(2+) or Mn(2+) ion per subunit.
{ECO:0000256|PIRNR:PIRNR000108};
-!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
dehydrogenases family. {ECO:0000256|PIRNR:PIRNR000108}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; X96728; CAA65504.1; -; mRNA.
UniGene; Nta.4240; -.
ProteinModelPortal; Q7DLX9; -.
GO; GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:UniProtKB-EC.
GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO; GO:0051287; F:NAD binding; IEA:InterPro.
GO; GO:0006102; P:isocitrate metabolic process; IEA:InterPro.
GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
InterPro; IPR004790; Isocitrate_DH_NADP.
InterPro; IPR024084; IsoPropMal-DH-like_dom.
PANTHER; PTHR11822; PTHR11822; 1.
Pfam; PF00180; Iso_dh; 1.
PIRSF; PIRSF000108; IDH_NADP; 1.
SMART; SM01329; Iso_dh; 1.
TIGRFAMs; TIGR00127; nadp_idh_euk; 1.
PROSITE; PS00470; IDH_IMDH; 1.
2: Evidence at transcript level;
Magnesium {ECO:0000256|PIRNR:PIRNR000108,
ECO:0000256|PIRSR:PIRSR000108-3};
Manganese {ECO:0000256|PIRNR:PIRNR000108,
ECO:0000256|PIRSR:PIRSR000108-3};
Metal-binding {ECO:0000256|PIRNR:PIRNR000108,
ECO:0000256|PIRSR:PIRSR000108-3};
NADP {ECO:0000256|PIRNR:PIRNR000108, ECO:0000256|PIRSR:PIRSR000108-4};
Oxidoreductase {ECO:0000256|PIRNR:PIRNR000108,
ECO:0000313|EMBL:CAA65504.1};
Tricarboxylic acid cycle {ECO:0000256|PIRNR:PIRNR000108}.
DOMAIN 66 456 Iso_dh. {ECO:0000259|SMART:SM01329}.
NP_BIND 132 134 NADP. {ECO:0000256|PIRSR:PIRSR000108-4}.
NP_BIND 366 371 NADP. {ECO:0000256|PIRSR:PIRSR000108-4}.
REGION 151 157 Substrate binding.
{ECO:0000256|PIRSR:PIRSR000108-2}.
METAL 308 308 Magnesium or manganese.
{ECO:0000256|PIRSR:PIRSR000108-3}.
METAL 331 331 Magnesium or manganese.
{ECO:0000256|PIRSR:PIRSR000108-3}.
BINDING 134 134 Substrate.
{ECO:0000256|PIRSR:PIRSR000108-2}.
BINDING 139 139 NADP. {ECO:0000256|PIRSR:PIRSR000108-4}.
BINDING 166 166 Substrate.
{ECO:0000256|PIRSR:PIRSR000108-2}.
BINDING 189 189 Substrate.
{ECO:0000256|PIRSR:PIRSR000108-2}.
BINDING 316 316 NADP. {ECO:0000256|PIRSR:PIRSR000108-4}.
BINDING 384 384 NADP; via amide nitrogen and carbonyl
oxygen. {ECO:0000256|PIRSR:PIRSR000108-
4}.
SITE 196 196 Critical for catalysis.
{ECO:0000256|PIRSR:PIRSR000108-1}.
SITE 268 268 Critical for catalysis.
{ECO:0000256|PIRSR:PIRSR000108-1}.
SEQUENCE 470 AA; 52515 MW; 32C920732685AC0C CRC64;
MASVASFISS SSASTSSAVT KNLPFSIISN RQLFKNRVYL LHRIPNASIR SFASTTASSK
IRVENPIVEM DGDEMTRVIW TMIKEKLIYP YLELDTKYYD LGILNRDATD DQVTVESAEA
TLKYNVAVKC ATITPDETRV KEFGLKSMWR SPNATIRNIL NGTVFREPIL CKNVPRIVPG
WKKPICIGRH AFGDQYRATD AVINGPGKLK MVFEPENGEA PTELDVYDFK GPGVALAMYN
VDQSIRAFAE SSMSMAFSKK WPLYLSTKNT ILKKYDGRFK DIFEEVYEEK WKQQFEEHSI
WYEHRLIDDM VAYALKSGGG YVWACKNYDG DVQSDLLAQG FGSLGLMTSV LLSSDGKTLE
AEAAHGTVTR HFRLHQKGQE TSTNSVASIF AWARGLGHRA QLDGNQKLSE FVHALEAACV
GTIESGKMTK DLAILVHGPK VSREHYLNTE EFIDPVAQKL QEKLGACAVV


Related products :

Catalog number Product name Quantity
LF-PA42092 Anti-Isocitrate Dehydrogenase (NADP+) (IDH1_IDH2), Rabbit Polyclonal to Isocitrate Dehydrogenase (NADP+) (IDH1_IDH2), Isotype IgG, Host Rabbit 50
10-663-45313 Isocitrate Dehydrogenase (NADP+) - N_A N_A 1 mg
BP076 Isocitrate dehydrogenase (NADP+) 1 ml
10-611-183017 Isocitrate Dehydrogenase (NADP - 150 Units
10-611-183017 Isocitrate Dehydrogenase (NADP - 600 Units
10-611-183017 Isocitrate Dehydrogenase (NADP - 300 Units
10-663-45313 Isocitrate Dehydrogenase (NADP+) - N_A N_A 50 mg
10-663-45313 Isocitrate Dehydrogenase (NADP+) - N_A N_A 0.5 mg
BP076 Isocitrate dehydrogenase (NADP+) 1 ml
5821 Mitochondrial NADP-isocitrate dehydrogenase 0.1 mg
341-02 Isocitrate Dehydrogenase (IDH) - NADP - Porcine - Liquid 1 kU
341-01 Isocitrate Dehydrogenase (IDH) - NADP - Porcine - Lyophilized 1 kU
5819 Cytosolic NADP-isocitrate dehydrogenase 0.5 mg
OETENZ-289 Isocitrate Dehydrogenase (NADP +) Recombinant 5mg
341-01 Isocitrate Dehydrogenase (IDH) - NADP - Porcine - Lyophilized 50 units
341-02 Isocitrate Dehydrogenase (IDH) - NADP - Porcine - Liquid 50 units
183017 Protein,Isocitrate Dehydrogenase (NADP 150 Units
OETENZ-289 Isocitrate Dehydrogenase (NADP +) Recombinant 1mg
183017 Protein,Isocitrate Dehydrogenase (NADP 600 Units
341-02 Isocitrate Dehydrogenase (IDH) - NADP - Porcine - Liquid 3 kU
341-02 Isocitrate Dehydrogenase (IDH) - NADP - Porcine - Liquid 500 units
5819 Cytosolic NADP-isocitrate dehydrogenase 0.1 mg
341-01 Isocitrate Dehydrogenase (IDH) - NADP - Porcine - Lyophilized 500 units
341-01 Isocitrate Dehydrogenase (IDH) - NADP - Porcine - Lyophilized 3 kU
5821 Mitochondrial NADP-isocitrate dehydrogenase 0.5 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur