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JMJD2B protein

 B7ZM63_HUMAN            Unreviewed;      1130 AA.
B7ZM63;
03-MAR-2009, integrated into UniProtKB/TrEMBL.
03-MAR-2009, sequence version 1.
05-JUL-2017, entry version 43.
SubName: Full=JMJD2B protein {ECO:0000313|EMBL:AAI44293.1};
Name=JMJD2B {ECO:0000313|EMBL:AAI44293.1};
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606 {ECO:0000313|EMBL:AAI44293.1};
[1] {ECO:0000313|EMBL:AAI44293.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M.,
Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S.,
Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F.,
Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J.,
Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N.,
Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B.,
Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B.,
Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S.,
Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R.,
Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L.,
Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E.,
Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D.,
Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G.,
Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J.,
Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L.,
Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D.,
Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A.,
Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S.,
Makowski K.A., Bosak S., Malek J.;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00773113}.
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EMBL; BC144292; AAI44293.1; -; mRNA.
UniGene; Hs.654816; -.
PaxDb; B7ZM63; -.
PeptideAtlas; B7ZM63; -.
PRIDE; B7ZM63; -.
eggNOG; ENOG410IT40; Eukaryota.
eggNOG; COG5141; LUCA.
HOVERGEN; HBG080483; -.
ChiTaRS; KDM4B; human.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
Gene3D; 3.30.40.10; -; 2.
InterPro; IPR034732; EPHD.
InterPro; IPR003347; JmjC_dom.
InterPro; IPR003349; JmjN.
InterPro; IPR002999; Tudor.
InterPro; IPR011011; Znf_FYVE_PHD.
InterPro; IPR001965; Znf_PHD.
InterPro; IPR013083; Znf_RING/FYVE/PHD.
Pfam; PF02373; JmjC; 1.
Pfam; PF02375; JmjN; 1.
SMART; SM00558; JmjC; 1.
SMART; SM00545; JmjN; 1.
SMART; SM00249; PHD; 2.
SMART; SM00333; TUDOR; 2.
SUPFAM; SSF57903; SSF57903; 1.
PROSITE; PS51805; EPHD; 1.
PROSITE; PS51184; JMJC; 1.
PROSITE; PS51183; JMJN; 1.
2: Evidence at transcript level;
Metal-binding {ECO:0000256|SAAS:SAAS00592111};
Nucleus {ECO:0000256|SAAS:SAAS00773228};
Zinc {ECO:0000256|SAAS:SAAS00592111};
Zinc-finger {ECO:0000256|SAAS:SAAS00592111}.
DOMAIN 15 57 JmjN. {ECO:0000259|PROSITE:PS51183}.
DOMAIN 146 309 JmjC. {ECO:0000259|PROSITE:PS51184}.
DOMAIN 828 941 PHD-type. {ECO:0000259|PROSITE:PS51805}.
SEQUENCE 1130 AA; 126058 MW; CE1DFC8B23446445 CRC64;
MGSEDHGAQN PSCKIMTFRP TMEEFKDFNK YVAYIESQGA HRAGLAKIIP PKEWKPRQTY
DDIDDVVIPA PIQQVVTGQS GLFTQYNIQK KAMTVGEYRR LANSEKYCTP RHQDFDDLER
KYWKNLTFVS PIYGADISGS LYDDDVAQWN IGSLRTILDM VERECGTIIE GVNTPYLYFG
MWKTTFAWHT EDMDLYSINY LHFGEPKSWY AIPPEHGKRL ERLAIGFFPG SSQGCDAFLR
HKMTLISPII LKKYGIPFSR ITQEAGEFMI TFPYGYHAGF NHGFNCAEST NFATLRWIDY
GKVATQCTCR KDMVKISMDV FVRILQPERY ELWKQGKDLT VLDHTRPTAL TSPELSSWSA
SRASLKAKLL RRQISLKENR HWRKTEEERK PSLERKKEQT KRPGLSSHRK RSQPKKPKPE
DPKFPGEGTA GAALLEEAGG SVKEEAGPEV DPEEEEEEPQ PLPHGREAEG AEEDGRGKLR
PTKAKSERKK KSFGLLPPQL PPPPAHFPSE EALWLPSPLE PPVLGPGPAA MEESPLPAPL
NVVPPEVPSE ELEAKPRPII PMLYVVPRPG KAAFNQEHVS CQQAFEHFAQ KGPTWKEPVS
PMELTGPEDG AASSGAGRME TKARAGEGQA PSTFSKLKME IKKSRRHPLG RPPTRSPLSV
VKQEASSDEE ASPFSGEEDV SDPDALRPLL SLQWKNMAAS FQAERKFNAA AARTEPYCAI
CTLFYPYCQA LQTEKEAPIA SLGEGCPATL PSKSRQKTRP LIPEMCFTSG GENTEPLPAN
SYIGDDGTSP LIACGKCCLQ VHASCYGIRP ELVNEGWTCS RCAAHAWTAE CCLCNLRGGA
LQMTTDRRWI HVICAIAVPE ARFLNVIERH PVDISAIPEQ RWKLKCVYCR KRMKKVSGAC
IQCSYEHCST SFHVTCAHAA GVLMEPDDWP YVVSITCLKH KSGGHAVQLL RAVSLGQVVI
TKNRNGLYYR CRVIGAASQT CYEVNFDDGS YSDNLYPESI TSRDCVQLGP PSEGELVELR
WTDGNLYKAK FISSVTSHIY QVEFEDGSQL TVKRGDIFTL EEELPKRVRS RLSLSTGAPQ
EPAFSGEEAK AAKRPRVGTP LATEDSGRSQ DYVAFVESLL QVQGRPGAPF


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