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Keratin-associated protein 10-9 (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9)

 KR109_HUMAN             Reviewed;         292 AA.
P60411; A2RRG1; A6NIR9; Q70LJ1;
16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
20-APR-2010, sequence version 2.
30-AUG-2017, entry version 108.
RecName: Full=Keratin-associated protein 10-9;
AltName: Full=High sulfur keratin-associated protein 10.9;
AltName: Full=Keratin-associated protein 10.9;
AltName: Full=Keratin-associated protein 18-9;
AltName: Full=Keratin-associated protein 18.9;
Name=KRTAP10-9;
Synonyms=KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
TISSUE=Hair root;
PubMed=15028290; DOI=10.1016/j.ygeno.2003.09.024;
Shibuya K., Obayashi I., Asakawa S., Minoshima S., Kudoh J.,
Shimizu N.;
"A cluster of 21 keratin-associated protein genes within introns of
another gene on human chromosome 21q22.3.";
Genomics 83:679-693(2004).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=10830953; DOI=10.1038/35012518;
Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T.,
Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y.,
Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K.,
Polley A., Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D.,
Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W.,
Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S.,
Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E.,
Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P.,
Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H.,
Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E.,
Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F.,
Lehrach H., Reinhardt R., Yaspo M.-L.;
"The DNA sequence of human chromosome 21.";
Nature 405:311-319(2000).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
Venter J.C.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANTS CYS-182 AND
CYS-257.
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[5]
NUCLEOTIDE SEQUENCE [MRNA] OF 244-292, TISSUE SPECIFICITY, AND VARIANT
CYS-257.
TISSUE=Scalp;
PubMed=14962103; DOI=10.1046/j.0022-202X.2003.22128.x;
Rogers M.A., Langbein L., Winter H., Beckmann I., Praetzel S.,
Schweizer J.;
"Hair keratin associated proteins: characterization of a second high
sulfur KAP gene domain on human chromosome 21.";
J. Invest. Dermatol. 122:147-158(2004).
-!- FUNCTION: In the hair cortex, hair keratin intermediate filaments
are embedded in an interfilamentous matrix, consisting of hair
keratin-associated proteins (KRTAP), which are essential for the
formation of a rigid and resistant hair shaft through their
extensive disulfide bond cross-linking with abundant cysteine
residues of hair keratins. The matrix proteins include the high-
sulfur and high-glycine-tyrosine keratins.
-!- SUBUNIT: Interacts with hair keratins.
-!- INTERACTION:
A8K932:-; NbExp=3; IntAct=EBI-10172052, EBI-10174671;
Q5XG85:-; NbExp=3; IntAct=EBI-10172052, EBI-10248413;
Q9H6F0:-; NbExp=3; IntAct=EBI-10172052, EBI-10307481;
Q9NWL9:-; NbExp=3; IntAct=EBI-10172052, EBI-10315054;
Q6UY14-3:ADAMTSL4; NbExp=5; IntAct=EBI-10172052, EBI-10173507;
Q08117:AES; NbExp=3; IntAct=EBI-10172052, EBI-717810;
P43353:ALDH3B1; NbExp=3; IntAct=EBI-10172052, EBI-2558314;
P09923:ALPI; NbExp=3; IntAct=EBI-10172052, EBI-1052631;
Q8N6T3:ARFGAP1; NbExp=3; IntAct=EBI-10172052, EBI-716933;
Q9ULK2:ATXN7L1; NbExp=3; IntAct=EBI-10172052, EBI-310660;
Q5T686:AVPI1; NbExp=3; IntAct=EBI-10172052, EBI-8640233;
A8KA13:BCL6B; NbExp=3; IntAct=EBI-10172052, EBI-10174813;
Q5T681:C10orf62; NbExp=3; IntAct=EBI-10172052, EBI-744052;
Q6NUJ2:C11orf87; NbExp=3; IntAct=EBI-10172052, EBI-6660291;
Q7L2K0:C16orf59; NbExp=3; IntAct=EBI-10172052, EBI-8465456;
Q0VDD7:C19orf57; NbExp=3; IntAct=EBI-10172052, EBI-741210;
A6NFR6-4:C5orf60; NbExp=3; IntAct=EBI-10172052, EBI-10173955;
Q7Z7H3:CATIP; NbExp=3; IntAct=EBI-10172052, EBI-10258233;
Q8NEC5:CATSPER1; NbExp=9; IntAct=EBI-10172052, EBI-744545;
Q14781:CBX2; NbExp=3; IntAct=EBI-10172052, EBI-745934;
Q8TAB7:CCDC26; NbExp=3; IntAct=EBI-10172052, EBI-10271580;
Q6UXG3:CD300LG; NbExp=3; IntAct=EBI-10172052, EBI-10254587;
Q8IVW4:CDKL3; NbExp=3; IntAct=EBI-10172052, EBI-3919850;
Q9UKJ5:CHIC2; NbExp=3; IntAct=EBI-10172052, EBI-741528;
Q9H2X0:CHRD; NbExp=3; IntAct=EBI-10172052, EBI-947551;
P07510:CHRNG; NbExp=3; IntAct=EBI-10172052, EBI-9008836;
P07510-2:CHRNG; NbExp=5; IntAct=EBI-10172052, EBI-11979451;
P61024:CKS1B; NbExp=3; IntAct=EBI-10172052, EBI-456371;
Q9HAZ1:CLK4; NbExp=3; IntAct=EBI-10172052, EBI-633400;
Q8NE01:CNNM3; NbExp=5; IntAct=EBI-10172052, EBI-741032;
Q8NE01-3:CNNM3; NbExp=3; IntAct=EBI-10172052, EBI-10269984;
Q9UGL9:CRCT1; NbExp=7; IntAct=EBI-10172052, EBI-713677;
Q02930-3:CREB5; NbExp=7; IntAct=EBI-10172052, EBI-10192698;
Q9H4G1:CST9L; NbExp=3; IntAct=EBI-10172052, EBI-3923092;
Q6P158:DHX57; NbExp=5; IntAct=EBI-10172052, EBI-1051531;
Q9NQL9:DMRT3; NbExp=5; IntAct=EBI-10172052, EBI-9679045;
Q92608:DOCK2; NbExp=3; IntAct=EBI-10172052, EBI-448771;
O60573:EIF4E2; NbExp=3; IntAct=EBI-10172052, EBI-398610;
Q15910-2:EZH2; NbExp=4; IntAct=EBI-10172052, EBI-10699473;
Q9H5Z6:FAM124B; NbExp=3; IntAct=EBI-10172052, EBI-741626;
Q3B820:FAM161A; NbExp=3; IntAct=EBI-10172052, EBI-719941;
Q5TZK3:FAM74A6; NbExp=3; IntAct=EBI-10172052, EBI-10247271;
Q5HYJ3:FAM76B; NbExp=3; IntAct=EBI-10172052, EBI-751192;
O95363:FARS2; NbExp=5; IntAct=EBI-10172052, EBI-2513774;
Q9H0R8:GABARAPL1; NbExp=3; IntAct=EBI-10172052, EBI-746969;
P60520:GABARAPL2; NbExp=3; IntAct=EBI-10172052, EBI-720116;
P23769:GATA2; NbExp=3; IntAct=EBI-10172052, EBI-2806671;
P43220:GLP1R; NbExp=3; IntAct=EBI-10172052, EBI-7466542;
O76003:GLRX3; NbExp=5; IntAct=EBI-10172052, EBI-374781;
Q9Y223:GNE; NbExp=3; IntAct=EBI-10172052, EBI-4291090;
Q9NWQ4:GPATCH2L; NbExp=3; IntAct=EBI-10172052, EBI-5666657;
P09211:GSTP1; NbExp=3; IntAct=EBI-10172052, EBI-353467;
D9YZU9:HBG2; NbExp=3; IntAct=EBI-10172052, EBI-10176884;
P02008:HBZ; NbExp=3; IntAct=EBI-10172052, EBI-719843;
P08631:HCK; NbExp=3; IntAct=EBI-10172052, EBI-346340;
P49639:HOXA1; NbExp=9; IntAct=EBI-10172052, EBI-740785;
P17482:HOXB9; NbExp=3; IntAct=EBI-10172052, EBI-745290;
P37235:HPCAL1; NbExp=5; IntAct=EBI-10172052, EBI-749311;
Q9H2F3:HSD3B7; NbExp=3; IntAct=EBI-10172052, EBI-3918847;
Q969P0:IGSF8; NbExp=3; IntAct=EBI-10172052, EBI-8293590;
Q92835:INPP5D; NbExp=3; IntAct=EBI-10172052, EBI-1380477;
Q8NA54:IQUB; NbExp=3; IntAct=EBI-10172052, EBI-10220600;
L7RT22:ITGB5; NbExp=3; IntAct=EBI-10172052, EBI-10178729;
Q92993:KAT5; NbExp=3; IntAct=EBI-10172052, EBI-399080;
Q2WGJ6:KLHL38; NbExp=3; IntAct=EBI-10172052, EBI-6426443;
P35900:KRT20; NbExp=3; IntAct=EBI-10172052, EBI-742094;
P78385:KRT83; NbExp=3; IntAct=EBI-10172052, EBI-10221390;
P60409:KRTAP10-7; NbExp=3; IntAct=EBI-10172052, EBI-10172290;
P60410:KRTAP10-8; NbExp=5; IntAct=EBI-10172052, EBI-10171774;
P59990:KRTAP12-1; NbExp=5; IntAct=EBI-10172052, EBI-10210845;
Q6PEX3:KRTAP26-1; NbExp=3; IntAct=EBI-10172052, EBI-3957672;
Q9BYQ6:KRTAP4-11; NbExp=5; IntAct=EBI-10172052, EBI-10302392;
Q9BQ66:KRTAP4-12; NbExp=5; IntAct=EBI-10172052, EBI-739863;
Q9BYR5:KRTAP4-2; NbExp=5; IntAct=EBI-10172052, EBI-10172511;
Q6L8G9:KRTAP5-6; NbExp=3; IntAct=EBI-10172052, EBI-10250562;
P26371:KRTAP5-9; NbExp=5; IntAct=EBI-10172052, EBI-3958099;
Q9BYQ4:KRTAP9-2; NbExp=6; IntAct=EBI-10172052, EBI-1044640;
Q9BYQ2:KRTAP9-4; NbExp=3; IntAct=EBI-10172052, EBI-10185730;
Q5T7P3:LCE1B; NbExp=7; IntAct=EBI-10172052, EBI-10245913;
Q5T752:LCE1D; NbExp=4; IntAct=EBI-10172052, EBI-11741311;
Q5T753:LCE1E; NbExp=4; IntAct=EBI-10172052, EBI-11955335;
Q5TA79:LCE2A; NbExp=5; IntAct=EBI-10172052, EBI-10246607;
Q5TA81:LCE2C; NbExp=4; IntAct=EBI-10172052, EBI-11973993;
Q5TA82:LCE2D; NbExp=5; IntAct=EBI-10172052, EBI-10246750;
Q5TA77:LCE3B; NbExp=4; IntAct=EBI-10172052, EBI-11974495;
Q5T5A8:LCE3C; NbExp=5; IntAct=EBI-10172052, EBI-10245291;
Q5T5B0:LCE3E; NbExp=6; IntAct=EBI-10172052, EBI-10245456;
Q5TA78:LCE4A; NbExp=5; IntAct=EBI-10172052, EBI-10246358;
Q9P127:LUZP4; NbExp=5; IntAct=EBI-10172052, EBI-10198848;
Q8N8X9:MAB21L3; NbExp=3; IntAct=EBI-10172052, EBI-10268010;
O60336:MAPKBP1; NbExp=3; IntAct=EBI-10172052, EBI-947402;
Q96HR3:MED30; NbExp=3; IntAct=EBI-10172052, EBI-394659;
P50222:MEOX2; NbExp=6; IntAct=EBI-10172052, EBI-748397;
Q13875:MOBP; NbExp=3; IntAct=EBI-10172052, EBI-10230628;
A1L3X4:MT1DP; NbExp=3; IntAct=EBI-10172052, EBI-10172129;
P50539-3:MXI1; NbExp=3; IntAct=EBI-10172052, EBI-10211940;
Q8IW45:NAXD; NbExp=3; IntAct=EBI-10172052, EBI-8650724;
Q9NQS3:NECTIN3; NbExp=3; IntAct=EBI-10172052, EBI-2826725;
Q7Z3S9:NOTCH2NL; NbExp=5; IntAct=EBI-10172052, EBI-945833;
P48146:NPBWR2; NbExp=3; IntAct=EBI-10172052, EBI-10210114;
Q9NQX5:NPDC1; NbExp=5; IntAct=EBI-10172052, EBI-748927;
P16860:NPPB; NbExp=3; IntAct=EBI-10172052, EBI-747044;
Q6NSM0:NR1D2; NbExp=4; IntAct=EBI-10172052, EBI-10250949;
Q7Z417:NUFIP2; NbExp=5; IntAct=EBI-10172052, EBI-1210753;
P32242:OTX1; NbExp=8; IntAct=EBI-10172052, EBI-740446;
Q9UHJ9:PGAP2; NbExp=3; IntAct=EBI-10172052, EBI-10321427;
Q13526:PIN1; NbExp=3; IntAct=EBI-10172052, EBI-714158;
O15162:PLSCR1; NbExp=3; IntAct=EBI-10172052, EBI-740019;
O43741:PRKAB2; NbExp=5; IntAct=EBI-10172052, EBI-1053424;
Q8WWY3:PRPF31; NbExp=6; IntAct=EBI-10172052, EBI-1567797;
P43115-12:PTGER3; NbExp=3; IntAct=EBI-10172052, EBI-10234038;
P15151:PVR; NbExp=3; IntAct=EBI-10172052, EBI-3919694;
Q9BSD3:RHNO1; NbExp=3; IntAct=EBI-10172052, EBI-9658624;
Q6UXX9:RSPO2; NbExp=3; IntAct=EBI-10172052, EBI-8481036;
Q9NUL5:RYDEN; NbExp=3; IntAct=EBI-10172052, EBI-10313866;
Q9NUL5-4:RYDEN; NbExp=4; IntAct=EBI-10172052, EBI-11955083;
Q8WTV0:SCARB1; NbExp=3; IntAct=EBI-10172052, EBI-78657;
Q9BWG6:SCNM1; NbExp=3; IntAct=EBI-10172052, EBI-748391;
Q9UHI7:SLC23A1; NbExp=3; IntAct=EBI-10172052, EBI-1759386;
Q9NP91:SLC6A20; NbExp=3; IntAct=EBI-10172052, EBI-10311198;
Q969G3:SMARCE1; NbExp=3; IntAct=EBI-10172052, EBI-455078;
P49901:SMCP; NbExp=7; IntAct=EBI-10172052, EBI-750494;
Q96E40:SPACA9; NbExp=3; IntAct=EBI-10172052, EBI-722584;
Q6RVD6:SPATA8; NbExp=3; IntAct=EBI-10172052, EBI-8635958;
Q9UQ90:SPG7; NbExp=3; IntAct=EBI-10172052, EBI-717201;
O43609:SPRY1; NbExp=5; IntAct=EBI-10172052, EBI-3866665;
O43597:SPRY2; NbExp=3; IntAct=EBI-10172052, EBI-742487;
O75716:STK16; NbExp=3; IntAct=EBI-10172052, EBI-749295;
Q9NUY8:TBC1D23; NbExp=3; IntAct=EBI-10172052, EBI-2853126;
Q9NUY8-2:TBC1D23; NbExp=3; IntAct=EBI-10172052, EBI-10314276;
O43493:TGOLN2; NbExp=3; IntAct=EBI-10172052, EBI-1752146;
Q9P2Z0:THAP10; NbExp=3; IntAct=EBI-10172052, EBI-745404;
O95407:TNFRSF6B; NbExp=3; IntAct=EBI-10172052, EBI-524171;
Q4VB56:TNP2; NbExp=3; IntAct=EBI-10172052, EBI-10241829;
Q8WV44:TRIM41; NbExp=5; IntAct=EBI-10172052, EBI-725997;
Q8IWZ5:TRIM42; NbExp=6; IntAct=EBI-10172052, EBI-5235829;
Q86UY0:TXNDC5; NbExp=3; IntAct=EBI-10172052, EBI-2825190;
Q8TAI1:TYMSOS; NbExp=3; IntAct=EBI-10172052, EBI-742060;
Q06418:TYRO3; NbExp=3; IntAct=EBI-10172052, EBI-3951628;
Q9BRU9:UTP23; NbExp=3; IntAct=EBI-10172052, EBI-5457544;
O96014:WNT11; NbExp=3; IntAct=EBI-10172052, EBI-8058160;
Q06250:WT1-AS; NbExp=3; IntAct=EBI-10172052, EBI-10223946;
Q9UBD3:XCL2; NbExp=3; IntAct=EBI-10172052, EBI-10319095;
Q9GZM5:YIPF3; NbExp=4; IntAct=EBI-10172052, EBI-743787;
O43167:ZBTB24; NbExp=3; IntAct=EBI-10172052, EBI-744471;
Q96C00:ZBTB9; NbExp=5; IntAct=EBI-10172052, EBI-395708;
Q96H43:ZFYVE26; NbExp=3; IntAct=EBI-10172052, EBI-10286915;
Q15973:ZNF124; NbExp=5; IntAct=EBI-10172052, EBI-2555767;
Q12901-2:ZNF155; NbExp=3; IntAct=EBI-10172052, EBI-10227379;
P17024:ZNF20; NbExp=3; IntAct=EBI-10172052, EBI-717634;
Q14C61:ZNF264; NbExp=3; IntAct=EBI-10172052, EBI-2826570;
Q96PQ6-4:ZNF317; NbExp=3; IntAct=EBI-10172052, EBI-10292528;
Q9P2F9:ZNF319; NbExp=4; IntAct=EBI-10172052, EBI-11993110;
Q8TAU3:ZNF417; NbExp=3; IntAct=EBI-10172052, EBI-740727;
Q8NDP4:ZNF439; NbExp=3; IntAct=EBI-10172052, EBI-747580;
Q8IYI8:ZNF440; NbExp=5; IntAct=EBI-10172052, EBI-726439;
Q8WTR7:ZNF473; NbExp=3; IntAct=EBI-10172052, EBI-751409;
Q8TBZ8:ZNF564; NbExp=3; IntAct=EBI-10172052, EBI-10273713;
Q7Z3I7:ZNF572; NbExp=6; IntAct=EBI-10172052, EBI-10172590;
Q3MI94:ZNF578; NbExp=3; IntAct=EBI-10172052, EBI-10241108;
Q9P0T4:ZNF581; NbExp=3; IntAct=EBI-10172052, EBI-745520;
Q96SQ5:ZNF587; NbExp=5; IntAct=EBI-10172052, EBI-6427977;
Q96I27:ZNF625; NbExp=3; IntAct=EBI-10172052, EBI-4395587;
Q8N508:ZNF697; NbExp=3; IntAct=EBI-10172052, EBI-10265733;
Q32M78:ZNF699; NbExp=3; IntAct=EBI-10172052, EBI-10217363;
Q96H86:ZNF764; NbExp=4; IntAct=EBI-10172052, EBI-745775;
Q3KQV3:ZNF792; NbExp=5; IntAct=EBI-10172052, EBI-10240849;
Q08AG5:ZNF844; NbExp=3; IntAct=EBI-10172052, EBI-10225757;
Q9Y5A6:ZSCAN21; NbExp=3; IntAct=EBI-10172052, EBI-10281938;
Q16670:ZSCAN26; NbExp=3; IntAct=EBI-10172052, EBI-3920053;
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=1;
Comment=A number of isoforms are produced.;
Name=1;
IsoId=P60411-1; Sequence=Displayed;
-!- TISSUE SPECIFICITY: Restricted to a narrow region of the hair
fiber cuticle, lying approximately 20 cell layers above the apex
of the dermal papilla of the hair root; not detected in any other
tissues. {ECO:0000269|PubMed:14962103,
ECO:0000269|PubMed:15028290}.
-!- SIMILARITY: Belongs to the KRTAP type 10 family. {ECO:0000305}.
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EMBL; AB076356; BAD01543.1; -; mRNA.
EMBL; AL773602; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CH471079; EAX09409.1; -; Genomic_DNA.
EMBL; CH471079; EAX09411.1; -; Genomic_DNA.
EMBL; BC131613; AAI31614.1; -; mRNA.
EMBL; AJ566386; CAD97466.1; -; mRNA.
CCDS; CCDS42961.1; -. [P60411-1]
RefSeq; NP_941963.2; NM_198690.2. [P60411-1]
RefSeq; NP_941965.2; NM_198692.2.
UniGene; Hs.474000; -.
UniGene; Hs.58076; -.
ProteinModelPortal; P60411; -.
BioGrid; 132127; 164.
BioGrid; 132129; 15.
IntAct; P60411; 215.
STRING; 9606.ENSP00000381009; -.
iPTMnet; P60411; -.
PhosphoSitePlus; P60411; -.
BioMuta; KRTAP10-9; -.
DMDM; 294862449; -.
PaxDb; P60411; -.
PeptideAtlas; P60411; -.
PRIDE; P60411; -.
Ensembl; ENST00000397911; ENSP00000381009; ENSG00000221837. [P60411-1]
GeneID; 386676; -.
GeneID; 386678; -.
KEGG; hsa:386676; -.
KEGG; hsa:386678; -.
UCSC; uc002zfp.5; human. [P60411-1]
CTD; 386676; -.
CTD; 386678; -.
GeneCards; KRTAP10-9; -.
H-InvDB; HIX0040852; -.
HGNC; HGNC:22971; KRTAP10-9.
neXtProt; NX_P60411; -.
PharmGKB; PA134873081; -.
eggNOG; ENOG410JNRG; Eukaryota.
eggNOG; ENOG41116YF; LUCA.
GeneTree; ENSGT00880000137966; -.
HOGENOM; HOG000234031; -.
HOVERGEN; HBG108072; -.
InParanoid; P60411; -.
OMA; SSYQPAC; -.
OrthoDB; EOG091G17RC; -.
PhylomeDB; P60411; -.
TreeFam; TF351356; -.
Reactome; R-HSA-6805567; Keratinization.
PRO; PR:P60411; -.
Proteomes; UP000005640; Chromosome 21.
Bgee; ENSG00000221837; -.
CleanEx; HS_KRTAP10-9; -.
ExpressionAtlas; P60411; baseline and differential.
GO; GO:0005829; C:cytosol; TAS:Reactome.
GO; GO:0045095; C:keratin filament; IEA:InterPro.
GO; GO:0031424; P:keratinization; TAS:Reactome.
InterPro; IPR002494; KAP.
PANTHER; PTHR23262; PTHR23262; 1.
Pfam; PF13885; Keratin_B2_2; 3.
1: Evidence at protein level;
Alternative splicing; Complete proteome; Keratin; Polymorphism;
Reference proteome; Repeat.
CHAIN 1 292 Keratin-associated protein 10-9.
/FTId=PRO_0000185217.
REPEAT 26 30 1.
REPEAT 31 35 2.
REPEAT 36 40 3.
REPEAT 57 61 4.
REPEAT 79 83 5.
REPEAT 99 103 6.
REPEAT 104 108 7.
REPEAT 109 113 8.
REPEAT 114 118 9.
REPEAT 120 124 10.
REPEAT 130 134 11.
REPEAT 140 144 12.
REPEAT 145 149 13.
REPEAT 150 154 14.
REPEAT 162 166 15.
REPEAT 172 176 16.
REPEAT 182 186 17.
REPEAT 187 191 18.
REPEAT 192 196 19.
REPEAT 197 201 20.
REPEAT 209 213 21.
REPEAT 219 223 22.
REPEAT 224 228 23.
REPEAT 243 247 24.
REPEAT 250 254 25.
REGION 26 254 25 X 5 AA repeats of C-C-X(3).
VARIANT 182 182 Y -> C (in dbSNP:rs8127342).
{ECO:0000269|PubMed:15489334}.
/FTId=VAR_017739.
VARIANT 257 257 R -> C (in dbSNP:rs9980129).
{ECO:0000269|PubMed:14962103,
ECO:0000269|PubMed:15489334}.
/FTId=VAR_060052.
CONFLICT 102 102 P -> PVCCKT (in Ref. 3; EAX09409).
{ECO:0000305}.
SEQUENCE 292 AA; 30037 MW; E61D891212803B98 CRC64;
MAASTMSIRS SAYSDSWQVD DCPESCCEPP CCATSCCAPA PCLTLVCTPV SRVSSPCCQV
TCEPSPCQSG CTSSCTPSCC QQSSCQPAYC TSSPCQQACC VPVCCKPVCC VPVCCGASSC
CQQSSYQPAC CASSSCQPAC CVPVCCKPVC CAPTCSEDSY SCCQQSSCQP ACCTSSPCQQ
SYCVPVCCKP VCCKPICCVP VCSGASSLCC QQSGCQPACC TTSCCRPSSS VSLLCRPVCR
PACCVPVSSC CAPTSSRQPS YCRQASCVSL LCRPVCSRPA CYSFSSGQKS SC


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