Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Laccase (EC 1.10.3.2) (Benzenediol:oxygen oxidoreductase) (Diphenol oxidase) (Urishiol oxidase)

 LAC1_NEUCR              Reviewed;         619 AA.
P06811; P10574; Q7RV60;
01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
28-NOV-2006, sequence version 3.
07-JUN-2017, entry version 127.
RecName: Full=Laccase;
EC=1.10.3.2;
AltName: Full=Benzenediol:oxygen oxidoreductase;
AltName: Full=Diphenol oxidase;
AltName: Full=Urishiol oxidase;
Flags: Precursor;
Name=lacc; ORFNames=NCU04528;
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM
1257 / FGSC 987).
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae;
Neurospora.
NCBI_TaxID=367110;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
STRAIN=Oak Ridge, and TS;
PubMed=2961749;
Germann U.A., Mueller G., Hunziker P.E., Lerch K.;
"Characterization of two allelic forms of Neurospora crassa laccase.
Amino- and carboxyl-terminal processing of a precursor.";
J. Biol. Chem. 263:885-896(1988).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
PubMed=12712197; DOI=10.1038/nature01554;
Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A.,
Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L.,
Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C.,
Marcotte E., Greenberg D., Roy A., Foley K., Naylor J.,
Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M.,
Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S.,
Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C.,
Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M.,
Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
"The genome sequence of the filamentous fungus Neurospora crassa.";
Nature 422:859-868(2003).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 379-619.
PubMed=2947240; DOI=10.1073/pnas.83.23.8854;
Germann U.A., Lerch K.;
"Isolation and partial nucleotide sequence of the laccase gene from
Neurospora crassa: amino acid sequence homology of the protein to
human ceruloplasmin.";
Proc. Natl. Acad. Sci. U.S.A. 83:8854-8858(1986).
-!- FUNCTION: Lignin degradation and detoxification of lignin-derived
products. {ECO:0000250}.
-!- CATALYTIC ACTIVITY: 4 benzenediol + O(2) = 4 benzosemiquinone + 2
H(2)O.
-!- COFACTOR:
Name=Cu cation; Xref=ChEBI:CHEBI:23378; Evidence={ECO:0000250};
Note=Binds 4 Cu cations per monomer. {ECO:0000250};
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
-!- SIMILARITY: Belongs to the multicopper oxidase family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; M18333; AAA33591.1; -; Genomic_DNA.
EMBL; M18334; AAA33592.1; -; Genomic_DNA.
EMBL; CM002242; EAA27703.1; -; Genomic_DNA.
EMBL; M14554; AAA33590.1; -; Genomic_DNA.
PIR; A28523; KSNCLO.
PIR; B28523; KSNCLT.
RefSeq; XP_956939.1; XM_951846.3.
ProteinModelPortal; P06811; -.
SMR; P06811; -.
CAZy; AA1; Auxiliary Activities 1.
PRIDE; P06811; -.
EnsemblFungi; EAA27703; EAA27703; NCU04528.
GeneID; 3873077; -.
KEGG; ncr:NCU04528; -.
EuPathDB; FungiDB:NCU04528; -.
HOGENOM; HOG000216827; -.
InParanoid; P06811; -.
OMA; FINAASH; -.
OrthoDB; EOG092C1CWL; -.
Proteomes; UP000001805; Chromosome 7, Linkage Group VII.
GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO; GO:0033573; C:high-affinity iron permease complex; IBA:GO_Central.
GO; GO:0005507; F:copper ion binding; IEA:InterPro.
GO; GO:0004322; F:ferroxidase activity; IBA:GO_Central.
GO; GO:0052716; F:hydroquinone:oxygen oxidoreductase activity; IEA:UniProtKB-EC.
GO; GO:0033215; P:iron assimilation by reduction and transport; IBA:GO_Central.
GO; GO:0034755; P:iron ion transmembrane transport; IEA:GOC.
GO; GO:0006826; P:iron ion transport; IBA:GO_Central.
GO; GO:0046274; P:lignin catabolic process; IEA:UniProtKB-KW.
Gene3D; 2.60.40.420; -; 3.
InterPro; IPR001117; Cu-oxidase.
InterPro; IPR011706; Cu-oxidase_2.
InterPro; IPR011707; Cu-oxidase_3.
InterPro; IPR033138; Cu_oxidase_CS.
InterPro; IPR002355; Cu_oxidase_Cu_BS.
InterPro; IPR008972; Cupredoxin.
Pfam; PF00394; Cu-oxidase; 1.
Pfam; PF07731; Cu-oxidase_2; 1.
Pfam; PF07732; Cu-oxidase_3; 1.
SUPFAM; SSF49503; SSF49503; 3.
PROSITE; PS00079; MULTICOPPER_OXIDASE1; 1.
PROSITE; PS00080; MULTICOPPER_OXIDASE2; 1.
1: Evidence at protein level;
Complete proteome; Copper; Direct protein sequencing; Glycoprotein;
Lignin degradation; Metal-binding; Oxidoreductase; Reference proteome;
Repeat; Secreted; Signal.
SIGNAL 1 21 {ECO:0000255}.
PROPEP 22 49
/FTId=PRO_0000002921.
CHAIN 50 606 Laccase.
/FTId=PRO_0000002922.
PROPEP 607 619
/FTId=PRO_0000002923.
DOMAIN 84 207 Plastocyanin-like 1.
DOMAIN 216 373 Plastocyanin-like 2.
DOMAIN 431 566 Plastocyanin-like 3.
METAL 144 144 Copper 1; type 2. {ECO:0000250}.
METAL 146 146 Copper 2; type 3. {ECO:0000250}.
METAL 189 189 Copper 2; type 3. {ECO:0000250}.
METAL 191 191 Copper 3; type 3. {ECO:0000250}.
METAL 477 477 Copper 4; type 1. {ECO:0000250}.
METAL 480 480 Copper 1; type 2. {ECO:0000250}.
METAL 482 482 Copper 3; type 3. {ECO:0000250}.
METAL 548 548 Copper 3; type 3. {ECO:0000250}.
METAL 549 549 Copper 4; type 1. {ECO:0000250}.
METAL 550 550 Copper 2; type 3. {ECO:0000250}.
METAL 554 554 Copper 4; type 1. {ECO:0000250}.
CARBOHYD 139 139 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 282 282 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 295 295 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 340 340 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 422 422 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 444 444 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
VARIANT 17 17 S -> P (in strain: Oak Ridge).
VARIANT 21 21 G -> A (in strain: Oak Ridge).
VARIANT 98 98 I -> L (in strain: TS).
VARIANT 114 114 K -> N (in strain: TS).
VARIANT 292 292 S -> L (in strain: Oak Ridge).
VARIANT 317 317 F -> L (in strain: TS).
VARIANT 320 320 V -> I (in strain: TS).
VARIANT 346 347 SK -> ND (in strain: TS).
VARIANT 351 351 D -> T (in strain: TS).
VARIANT 355 355 H -> K (in strain: TS).
VARIANT 374 374 Q -> K (in strain: TS).
VARIANT 379 379 V -> P (in strain: TS).
VARIANT 439 439 L -> M (in strain: TS).
SEQUENCE 619 AA; 68148 MW; DD7C67B9135FC08A CRC64;
MKFLGIAALV AGLLAPSLVL GAPAPGTEGV NLLTPVDKRQ DSQAERYGGG GGGGCNSPTN
RQCWSPGFNI NTDYELGTPN TGKTRRYKLT LTETDNWIGP DGVIKDKVMM VNDKIIGPTI
QADWGDYIEI TVINKLKSNG TSIHWHGMHQ RNSNIQDGVN GVTECPIPPR GGSKVYRWRA
TQYGTSWYHS HFSAQYGNGI VGPIVINGPA SANYDVDLGP FPLTDYYYDT ADRLVLLTQH
AGPPPSNNVL FNGFAKHPTT GAGQYATVSL TKGKKHRLRL INTSVENHFQ LSLVNHSMTI
ISADLVPVQP YKVDSLFLGV GQRYDVIIDA NQAVGNYWFN VTFGGSKLCG DSDNHYPAAI
FRYQGAPKAL PTNQGVAPVD HQCLDLNDLK PVLQRSLNTN SIALNTGNTI PITLDGFVWR
VNGTAININW NKPVLEYVLT GNTNYSQSDN IVQVEGVNQW KYWLIENDPD GAFSLPHPIH
LHGHDFLILG RSPDVTAISQ TRYVFDPAVD MARLNGNNPT RRDTAMLPAK GWLLIAFRTD
NPGSWLMHCH IAWHVSGGLS NQFLERAQDL RNSISPADKK AFNDNCDAWR AYFPDNAPFP
KDDSGLRSGV KAREVKMKW


Related products :

Catalog number Product name Quantity
EIAAB27575 Kidney oxidase-1,Kidney superoxide-producing NADPH oxidase,KOX-1,Mouse,Mus musculus,NADPH oxidase 4,Nox4,Renal NAD(P)H-oxidase,Renox,Superoxide-generating NADPH oxidase 4
EIAAB27574 Homo sapiens,Human,Kidney oxidase-1,Kidney superoxide-producing NADPH oxidase,KOX-1,NADPH oxidase 4,NOX4,Renal NAD(P)H-oxidase,RENOX
EIAAB39256 Bos taurus,Bovine,L-pipecolate oxidase,L-pipecolic acid oxidase,Peroxisomal sarcosine oxidase,PIPOX,PSO
EIAAB39255 L-pipecolate oxidase,L-pipecolic acid oxidase,Mouse,Mus musculus,Peroxisomal sarcosine oxidase,Pipox,PSO,Pso
EIAAB39254 L-pipecolate oxidase,L-pipecolic acid oxidase,Oryctolagus cuniculus,Peroxisomal sarcosine oxidase,PIPOX,PSO,PSO,Rabbit,SOX
EIAAB39257 Homo sapiens,Human,L-pipecolate oxidase,L-pipecolic acid oxidase,LPIPOX,Peroxisomal sarcosine oxidase,PIPOX,PSO,PSO
EIAAB27568 Homo sapiens,Human,Mitogenic oxidase 1,MOX1,MOX-1,NADH_NADPH mitogenic oxidase subunit P65-MOX,NADPH oxidase 1,NOH1,NOH-1,NOX1,NOX-1
EIAAB32432 Kidney and liver proline oxidase 1,MmPOX1,Mouse,Mus musculus,PO,Probable proline dehydrogenase 2,Probable proline oxidase 2,Prodh2,Proline oxidase,Proline oxidase-like protein
EIAAB12028 Dual oxidase 1,DUOX,DUOX1,Homo sapiens,Human,Large NOX 1,LNOX1,Long NOX 1,NADPH thyroid oxidase 1,THOX1,Thyroid oxidase 1
EIAAB27569 Mitogenic oxidase 1,Mox1,MOX-1,NADH_NADPH mitogenic oxidase subunit P65-MOX,NADPH oxidase 1,Noh1,NOH-1,Nox1,NOX-1,Rat,Rattus norvegicus
EIAAB08789 COX8B,COX8H,Cytochrome c oxidase polypeptide VIII-liver_heart,Cytochrome c oxidase subunit 8-1,Cytochrome c oxidase subunit 8B, mitochondrial,Cytochrome c oxidase subunit 8H,Oryctolagus cuniculus,Rabb
EIAAB08785 Bos taurus,Bovine,COX8B,COX8H,Cytochrome c oxidase polypeptide VIII-heart,Cytochrome c oxidase subunit 8-1,Cytochrome c oxidase subunit 8B, mitochondrial,Cytochrome c oxidase subunit 8H,IX,VIIIb
15-288-22819 Acyl-coenzyme A oxidase 1. peroxisomal - EC 1.3.3.6; Palmitoyl-CoA oxidase; AOX; Straight-chain acyl-CoA oxidase; SCOX Polyclonal 0.1 mg
15-288-22819 Acyl-coenzyme A oxidase 1. peroxisomal - EC 1.3.3.6; Palmitoyl-CoA oxidase; AOX; Straight-chain acyl-CoA oxidase; SCOX Polyclonal 0.05 mg
EIAAB08787 Cox8b,Cox8h,Cytochrome c oxidase polypeptide VIII-heart,Cytochrome c oxidase subunit 8-1,Cytochrome c oxidase subunit 8B, mitochondrial,Cytochrome c oxidase subunit 8H,Mouse,Mus musculus
EIAAB08788 Cox8b,Cox8h,Cytochrome c oxidase polypeptide VIII-heart,Cytochrome c oxidase subunit 8-1,Cytochrome c oxidase subunit 8B, mitochondrial,Cytochrome c oxidase subunit 8H,Rat,Rattus norvegicus
EIAAB12031 Dual oxidase 2,DUOX2,Homo sapiens,Human,Large NOX 2,LNOX2,Long NOX 2,NADH_NADPH thyroid oxidase p138-tox,NADPH oxidase_peroxidase DUOX2,NADPH thyroid oxidase 2,p138 thyroid oxidase,THOX2,Thyroid oxida
EIAAB10091 Bos taurus,Bovine,COX VIb-1,COX6B,COX6B1,Cytochrome c oxidase polypeptide VII,Cytochrome c oxidase subunit 6B1,Cytochrome c oxidase subunit AED,Cytochrome c oxidase subunit VIb isoform 1
E0656h ELISA kit ABP,ABP1,Amiloride-binding protein,Amiloride-sensitive amine oxidase [copper-containing],AOC1,DAO,DAO1,Diamine oxidase,Histaminase,Homo sapiens,Human,KAO,Kidney amine oxidase 96T
E0656h ELISA ABP,ABP1,Amiloride-binding protein,Amiloride-sensitive amine oxidase [copper-containing],AOC1,DAO,DAO1,Diamine oxidase,Histaminase,Homo sapiens,Human,KAO,Kidney amine oxidase 96T
U0656h CLIA ABP,ABP1,Amiloride-binding protein,Amiloride-sensitive amine oxidase [copper-containing],AOC1,DAO,DAO1,Diamine oxidase,Histaminase,Homo sapiens,Human,KAO,Kidney amine oxidase 96T
EIAAB12033 Dual oxidase 2,Duox2,Large NOX 2,Lnox2,Long NOX 2,NADH_NADPH thyroid oxidase THOX2,Rat,Rattus norvegicus,Thox2,Thyroid oxidase 2
EIAAB10105 COX7A2,COX7AL,Cytochrome c oxidase subunit 7A2, mitochondrial,Cytochrome c oxidase subunit VIIaL,Cytochrome c oxidase subunit VIIa-L,Cytochrome c oxidase subunit VIIa-liver_heart,Homo sapiens,Human
EIAAB08786 Canis familiaris,Canis lupus familiaris,COX8B,COX8H,Cytochrome c oxidase polypeptide VIII-heart,Cytochrome c oxidase subunit 8-1,Cytochrome c oxidase subunit 8B, mitochondrial,Cytochrome c oxidase sub
EIAAB10086 COX VIa-M,COX6A,COX6A2,COX6AH,COXVIAH,Cytochrome c oxidase polypeptide VIa-heart,Cytochrome c oxidase subunit 6A2, mitochondrial,Cytochrome c oxidase subunit VIA-muscle,Homo sapiens,Human


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur





GENTAUR Ltd.
Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur