Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Small integral membrane protein of lysosome/late endosome)

 LITAF_CHICK             Reviewed;         148 AA.
Q8QGW7;
06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
01-JUN-2002, sequence version 1.
30-AUG-2017, entry version 70.
RecName: Full=Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog;
Short=LPS-induced TNF-alpha factor homolog;
AltName: Full=Small integral membrane protein of lysosome/late endosome;
Name=LITAF; Synonyms=SIMPLE;
Gallus gallus (Chicken).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
Phasianidae; Phasianinae; Gallus.
NCBI_TaxID=9031;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
TISSUE=Thymus;
Moriwaki Y., Begum N.A., Kobayashi M., Matsumoto M., Seya T.;
"Molecular cloning and functional characterizaiton of chicken SIMPLE,
a human SIMPLE ortholog.";
Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [MRNA].
Lillehoj H.S., Min W., Ashwell C.M., Matukumalli L.K., van Tassel C.,
Han J.Y.;
"Gallus gallus TNF-alpha factor.";
Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Plays a role in endosomal protein trafficking and in
targeting proteins for lysosomal degradation. May also contribute
to the regulation of gene expression in the nucleus. Binds DNA (in
vitro) and may play a synergistic role in the nucleus in
regulating the expression of numerous cytokines.
{ECO:0000250|UniProtKB:Q99732}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q99732}.
Nucleus {ECO:0000250|UniProtKB:Q99732}. Lysosome membrane
{ECO:0000250|UniProtKB:Q99732}; Peripheral membrane protein
{ECO:0000250|UniProtKB:Q99732}; Cytoplasmic side
{ECO:0000250|UniProtKB:Q99732}. Early endosome membrane
{ECO:0000250|UniProtKB:Q99732}. Late endosome membrane
{ECO:0000250|UniProtKB:Q99732}. Endosome membrane
{ECO:0000250|UniProtKB:Q99732}; Peripheral membrane protein
{ECO:0000250|UniProtKB:Q99732}; Cytoplasmic side
{ECO:0000250|UniProtKB:Q99732}. Cell membrane
{ECO:0000250|UniProtKB:Q99732}; Peripheral membrane protein
{ECO:0000250|UniProtKB:Q99732}; Cytoplasmic side
{ECO:0000250|UniProtKB:Q99732}. Golgi apparatus membrane
{ECO:0000250|UniProtKB:Q99732}. Note=Associated with membranes of
lysosomes, early and late endosomes. Can translocate from the
cytoplasm into the nucleus (By similarity). Detected at Schmidt-
Lanterman incisures and in nodal regions of myelinating Schwann
cells (By similarity). {ECO:0000250|UniProtKB:Q99732,
ECO:0000250|UniProtKB:Q9JLJ0}.
-!- DOMAIN: The LITAF domain is stabilized by a bound zinc ion. The
LITAF domain contains an amphiphatic helix that mediates
interaction with lipid membranes. {ECO:0000250|UniProtKB:Q99732}.
-!- SIMILARITY: Belongs to the CDIP1/LITAF family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AB058634; BAB85678.1; -; mRNA.
EMBL; AB061737; BAC58022.1; -; Genomic_DNA.
EMBL; AY765397; AAU95774.1; -; mRNA.
RefSeq; NP_989598.1; NM_204267.1.
UniGene; Gga.3383; -.
STRING; 9031.ENSGALP00000005086; -.
PaxDb; Q8QGW7; -.
GeneID; 374125; -.
KEGG; gga:374125; -.
CTD; 9516; -.
eggNOG; ENOG410IVVU; Eukaryota.
eggNOG; ENOG41122PJ; LUCA.
HOGENOM; HOG000039585; -.
HOVERGEN; HBG006272; -.
InParanoid; Q8QGW7; -.
KO; K19363; -.
PhylomeDB; Q8QGW7; -.
PRO; PR:Q8QGW7; -.
Proteomes; UP000000539; Unplaced.
GO; GO:0098559; C:cytoplasmic side of early endosome membrane; ISS:UniProtKB.
GO; GO:0098560; C:cytoplasmic side of late endosome membrane; ISS:UniProtKB.
GO; GO:0098574; C:cytoplasmic side of lysosomal membrane; ISS:UniProtKB.
GO; GO:0009898; C:cytoplasmic side of plasma membrane; ISS:UniProtKB.
GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO; GO:0005765; C:lysosomal membrane; TAS:AgBase.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0005125; F:cytokine activity; NAS:AgBase.
GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO; GO:0001816; P:cytokine production; TAS:AgBase.
GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
GO; GO:0019953; P:sexual reproduction; TAS:AgBase.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
InterPro; IPR006629; LITAF.
Pfam; PF10601; zf-LITAF-like; 1.
SMART; SM00714; LITAF; 1.
PROSITE; PS51837; LITAF; 1.
2: Evidence at transcript level;
Cell membrane; Complete proteome; Cytoplasm; DNA-binding; Endosome;
Golgi apparatus; Lysosome; Membrane; Metal-binding; Nucleus;
Reference proteome; Transcription; Transcription regulation; Zinc.
CHAIN 1 148 Lipopolysaccharide-induced tumor necrosis
factor-alpha factor homolog.
/FTId=PRO_0000084443.
DOMAIN 62 147 LITAF. {ECO:0000255|PROSITE-
ProRule:PRU01181}.
REGION 103 123 Membrane-binding amphipathic helix.
{ECO:0000305}.
MOTIF 13 16 WW-binding.
{ECO:0000250|UniProtKB:Q99732}.
METAL 83 83 Zinc. {ECO:0000250|UniProtKB:Q99732}.
METAL 86 86 Zinc. {ECO:0000250|UniProtKB:Q99732}.
METAL 135 135 Zinc. {ECO:0000250|UniProtKB:Q99732}.
METAL 138 138 Zinc. {ECO:0000250|UniProtKB:Q99732}.
SEQUENCE 148 AA; 16013 MW; BA4A52B60B7A59E8 CRC64;
MSAPSGFPAP SAPPSYEETV GINVNYPHPY PVPQPGLRPD GKGMNPPQYS GQPMPTSTPV
TVQTVYVQQP VVLFYDRPVQ MSCPSCNQMI VTRLCYESGA LTWLSCGGLF LLGCIAGCCL
IPFCVDALKD VEHFCPNCNA HVGSYKRL


Related products :

Catalog number Product name Quantity
LITAF_MOUSE ELISA Kit FOR Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog; organism: Mouse; gene name: Litaf 96T
U0651h CLIA Homo sapiens,Human,Hyaluronate-binding protein,TNF alpha-induced protein 6,TNFAIP6,TNF-stimulated gene 6 protein,TSG6,TSG-6,Tumor necrosis factor alpha-induced protein 6,Tumor necrosis factor-ind 96T
E0651h ELISA Homo sapiens,Human,Hyaluronate-binding protein,TNF alpha-induced protein 6,TNFAIP6,TNF-stimulated gene 6 protein,TSG6,TSG-6,Tumor necrosis factor alpha-induced protein 6,Tumor necrosis factor-in 96T
CSB-EL012985RA Rat Lipopolysaccharide-induced tumor necrosis factor-alpha factor(LITAF) ELISA kit 96T
CSB-EL012985HU Human Lipopolysaccharide-induced tumor necrosis factor-alpha factor(LITAF) ELISA kit 96T
CSB-EL012985MO Mouse Lipopolysaccharide-induced tumor necrosis factor-alpha factor(LITAF) ELISA kit 96T
CSB-EL012985RA Rat Lipopolysaccharide-induced tumor necrosis factor-alpha factor(LITAF) ELISA kit SpeciesRat 96T
CSB-EL012985CH Chicken Lipopolysaccharide-induced tumor necrosis factor-alpha factor(LITAF) ELISA kit 96T
CSB-EL012985HU Human Lipopolysaccharide-induced tumor necrosis factor-alpha factor(LITAF) ELISA kit SpeciesHuman 96T
CSB-EL012985CH Chicken Lipopolysaccharide-induced tumor necrosis factor-alpha factor(LITAF) ELISA kit SpeciesChicken 96T
CSB-EL012985MO Mouse Lipopolysaccharide-induced tumor necrosis factor-alpha factor(LITAF) ELISA kit SpeciesMouse 96T
E0651m ELISA Mouse,Mus musculus,TNF alpha-induced protein 6,Tnfaip6,Tnfip6,TNF-stimulated gene 6 protein,Tsg6,TSG-6,Tumor necrosis factor alpha-induced protein 6,Tumor necrosis factor-inducible gene 6 protei 96T
E0651m ELISA kit Mouse,Mus musculus,TNF alpha-induced protein 6,Tnfaip6,Tnfip6,TNF-stimulated gene 6 protein,Tsg6,TSG-6,Tumor necrosis factor alpha-induced protein 6,Tumor necrosis factor-inducible gene 6 p 96T
U0651m CLIA Mouse,Mus musculus,TNF alpha-induced protein 6,Tnfaip6,Tnfip6,TNF-stimulated gene 6 protein,Tsg6,TSG-6,Tumor necrosis factor alpha-induced protein 6,Tumor necrosis factor-inducible gene 6 protein 96T
EIAAB43494 Homo sapiens,Human,Inflammation factor protein 20,TIPE2,TNF alpha-induced protein 8-like protein 2,TNFAIP8L2,TNFAIP8-like protein 2,Tumor necrosis factor alpha-induced protein 8-like protein 2
E0651h ELISA kit Homo sapiens,Human,Hyaluronate-binding protein,TNF alpha-induced protein 6,TNFAIP6,TNF-stimulated gene 6 protein,TSG6,TSG-6,Tumor necrosis factor alpha-induced protein 6,Tumor necrosis fact 96T
E0651Rb ELISA Hyaluronate-binding protein PS4,Oryctolagus cuniculus,PS4,Rabbit,TNF alpha-induced protein 6,TNFAIP6,TNF-stimulated gene 6 protein,TSG6,TSG-6,Tumor necrosis factor alpha-induced protein 6,Tumor 96T
U0651Rb CLIA Hyaluronate-binding protein PS4,Oryctolagus cuniculus,PS4,Rabbit,TNF alpha-induced protein 6,TNFAIP6,TNF-stimulated gene 6 protein,TSG6,TSG-6,Tumor necrosis factor alpha-induced protein 6,Tumor n 96T
EIAAB43275 Homo sapiens,Human,Primary response gene B94 protein,TNF alpha-induced protein 2,TNFAIP2,Tumor necrosis factor alpha-induced protein 2
EIAAB42117 Mouse,Mus musculus,TNF alpha-induced protein 8,Tnfaip8,Tumor necrosis factor alpha-induced protein 8
EIAAB42120 Bos taurus,Bovine,TNF alpha-induced protein 8,TNFAIP8,Tumor necrosis factor alpha-induced protein 8
EIAAB43274 Mouse,Mus musculus,Primary response gene B94 protein,TNF alpha-induced protein 2,Tnfaip2,Tumor necrosis factor alpha-induced protein 2
EIAAB43276 Mouse,Mus musculus,Putative DNA-binding protein A20,TNF alpha-induced protein 3,Tnfaip3,Tnfip3,Tumor necrosis factor alpha-induced protein 3,Zinc finger protein A20
E0651Rb ELISA kit Hyaluronate-binding protein PS4,Oryctolagus cuniculus,PS4,Rabbit,TNF alpha-induced protein 6,TNFAIP6,TNF-stimulated gene 6 protein,TSG6,TSG-6,Tumor necrosis factor alpha-induced protein 6,T 96T
EIAAB43277 Homo sapiens,Human,OTU domain-containing protein 7C,OTUD7C,Putative DNA-binding protein A20,TNF alpha-induced protein 3,TNFAIP3,Tumor necrosis factor alpha-induced protein 3,Zinc finger protein A20


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur