Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

MDM2 proto-oncogene

 M3Z1D2_MUSPF            Unreviewed;       487 AA.
M3Z1D2;
01-MAY-2013, integrated into UniProtKB/TrEMBL.
01-MAY-2013, sequence version 1.
31-JAN-2018, entry version 37.
SubName: Full=MDM2 proto-oncogene {ECO:0000313|Ensembl:ENSMPUP00000017394};
Name=MDM2 {ECO:0000313|Ensembl:ENSMPUP00000017394};
Mustela putorius furo (European domestic ferret) (Mustela furo).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Mustelidae;
Mustelinae; Mustela.
NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000017394, ECO:0000313|Proteomes:UP000000715};
[1] {ECO:0000313|Ensembl:ENSMPUP00000017394}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ID#1420 {ECO:0000313|Ensembl:ENSMPUP00000017394};
Di Palma F., Alfoldi J., Johnson J., Jaffe D., Berlin A., Gnerre S.,
Grabherr M., Hall G., Lara M., MacCallum I., Mauceli E.,
Przyblyski D., Ribeiro F., Russell P., Sharpe T., Turner-Maier J.,
Walker B.J., Young S., Birren B., Lindblad-Toh K.;
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSMPUP00000017394}
IDENTIFICATION.
Ensembl;
Submitted (MAR-2013) to UniProtKB.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSMPUP00000017394}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AEYP01031532; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AEYP01031533; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AEYP01031534; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AEYP01031535; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AEYP01031536; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; XP_004752513.1; XM_004752456.2.
RefSeq; XP_004752514.1; XM_004752457.2.
STRING; 9669.ENSMPUP00000017394; -.
Ensembl; ENSMPUT00000017651; ENSMPUP00000017394; ENSMPUG00000017505.
GeneID; 101689782; -.
CTD; 4193; -.
eggNOG; ENOG410IGXG; Eukaryota.
eggNOG; ENOG41125MP; LUCA.
GeneTree; ENSGT00530000063539; -.
InParanoid; M3Z1D2; -.
OMA; PCVICQS; -.
OrthoDB; EOG091G0FYK; -.
Proteomes; UP000000715; Unassembled WGS sequence.
GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
GO; GO:0016604; C:nuclear body; IEA:Ensembl.
GO; GO:0005730; C:nucleolus; IEA:Ensembl.
GO; GO:0043234; C:protein complex; IEA:Ensembl.
GO; GO:0008097; F:5S rRNA binding; IEA:Ensembl.
GO; GO:0097718; F:disordered domain specific binding; IEA:Ensembl.
GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
GO; GO:0016874; F:ligase activity; IEA:Ensembl.
GO; GO:0061663; F:NEDD8 ligase activity; IEA:Ensembl.
GO; GO:0002039; F:p53 binding; IEA:Ensembl.
GO; GO:0047485; F:protein N-terminus binding; IEA:Ensembl.
GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:Ensembl.
GO; GO:0097110; F:scaffold protein binding; IEA:Ensembl.
GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:Ensembl.
GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:Ensembl.
GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
GO; GO:1990000; P:amyloid fibril formation; IEA:Ensembl.
GO; GO:0003283; P:atrial septum development; IEA:Ensembl.
GO; GO:0003181; P:atrioventricular valve morphogenesis; IEA:Ensembl.
GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
GO; GO:0060411; P:cardiac septum morphogenesis; IEA:Ensembl.
GO; GO:0072717; P:cellular response to actinomycin D; IEA:Ensembl.
GO; GO:0071480; P:cellular response to gamma radiation; IEA:Ensembl.
GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IEA:Ensembl.
GO; GO:0003203; P:endocardial cushion morphogenesis; IEA:Ensembl.
GO; GO:0045184; P:establishment of protein localization; IEA:Ensembl.
GO; GO:0071157; P:negative regulation of cell cycle arrest; IEA:Ensembl.
GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IEA:Ensembl.
GO; GO:1902254; P:negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Ensembl.
GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
GO; GO:0018205; P:peptidyl-lysine modification; IEA:Ensembl.
GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
GO; GO:0051865; P:protein autoubiquitination; IEA:Ensembl.
GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
GO; GO:0031648; P:protein destabilization; IEA:Ensembl.
GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl.
GO; GO:0002027; P:regulation of heart rate; IEA:Ensembl.
GO; GO:0007089; P:traversing start control point of mitotic cell cycle; IEA:Ensembl.
GO; GO:0003281; P:ventricular septum development; IEA:Ensembl.
Gene3D; 1.10.245.10; -; 1.
Gene3D; 3.30.40.10; -; 1.
InterPro; IPR028340; Mdm2.
InterPro; IPR015459; MDM2_E3_ligase.
InterPro; IPR016495; p53_neg-reg_MDM_2/4.
InterPro; IPR036885; SWIB_MDM2_dom_sf.
InterPro; IPR003121; SWIB_MDM2_domain.
InterPro; IPR001876; Znf_RanBP2.
InterPro; IPR036443; Znf_RanBP2_sf.
InterPro; IPR001841; Znf_RING.
InterPro; IPR013083; Znf_RING/FYVE/PHD.
PANTHER; PTHR13844:SF15; PTHR13844:SF15; 1.
Pfam; PF02201; SWIB; 1.
Pfam; PF00641; zf-RanBP; 1.
PIRSF; PIRSF500700; MDM2; 1.
PIRSF; PIRSF006748; p53_MDM_2/4; 1.
SUPFAM; SSF47592; SSF47592; 2.
SUPFAM; SSF90209; SSF90209; 1.
PROSITE; PS01358; ZF_RANBP2_1; 1.
PROSITE; PS50199; ZF_RANBP2_2; 1.
PROSITE; PS50089; ZF_RING_2; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000000715};
Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175,
ECO:0000256|SAAS:SAAS00581830};
Reference proteome {ECO:0000313|Proteomes:UP000000715};
Zinc {ECO:0000256|PROSITE-ProRule:PRU00175,
ECO:0000256|SAAS:SAAS00581830};
Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175,
ECO:0000256|SAAS:SAAS00581830}.
DOMAIN 299 328 RanBP2-type.
{ECO:0000259|PROSITE:PS50199}.
DOMAIN 434 475 RING-type. {ECO:0000259|PROSITE:PS50089}.
SEQUENCE 487 AA; 54904 MW; 0CE1144A8AAB4EE6 CRC64;
MCNTNMSVST DGAVSTSQMP ASEQETLVRP KPLLLKLLKS VGAQKDTYTM KEVIFYLGQY
IMTKRLYDEK QQHIVYCSND LLGDLFGVPS FSVKEHRKIY TMIYRNLVVV NQHESSDSGT
SVSENRCHLE GGSDQKDPVQ ELQEEKPSSS DLVSRPSTSS RRRTISETEE HSDELPGERQ
RKRHKSDSIS LSFDESLALC VIREICCERS SSSESTGTPS NPDLDAGVSE QSGDWLDQDS
VSDQFSVEFE VESLDSEDYG LSEEGQELSD DDDEVYRVTV YQAEESDTDS FEEDPEISLA
DYWKCTSCSE MNPPLPPHCN RCWALRENWL PEDKGKMPEK AKLENSTQVE EGFDVPDCKK
SSVSDSREPC AEENDDKITQ ASQSQESEDF SQPSTSNSII YSSQEDVKEF EREETQDKEE
IVESSFPLNA IEPCVICQGR PKNGCIVHGK TGHLMACFTC AKKLKKRNKP CPVCRQPIQM
IVLTYFP


Related products :

Catalog number Product name Quantity
EIAAB14724 Feline sarcoma_Fujinami avian sarcoma oncogene homolog,FES,FPS,Homo sapiens,Human,p93c-fes,Proto-oncogene c-Fes,Proto-oncogene c-Fps,Tyrosine-protein kinase Fes_Fps
EIAAB33701 cRaf,Homo sapiens,Human,Proto-oncogene c-RAF,RAF,RAF proto-oncogene serine_threonine-protein kinase,RAF1,Raf-1
EIAAB39852 Homo sapiens,Human,p60-Src,pp60c-src,Proto-oncogene c-Src,Proto-oncogene tyrosine-protein kinase Src,SRC,SRC1
EIAAB25170 Mos,Oocyte maturation factor mos,Proto-oncogene c-Mos,Proto-oncogene serine_threonine-protein kinase mos,Rat,Rattus norvegicus
EIAAB25166 Mos,Mouse,Mus musculus,Oocyte maturation factor mos,Proto-oncogene c-Mos,Proto-oncogene serine_threonine-protein kinase mos
EIAAB25167 Homo sapiens,Human,MOS,Oocyte maturation factor mos,Proto-oncogene c-Mos,Proto-oncogene serine_threonine-protein kinase mos
EIAAB35721 Homo sapiens,Human,Proto-oncogene c-Ros-1,Proto-oncogene tyrosine-protein kinase ROS,ROS1
EIAAB39851 Mouse,Mus musculus,Neuronal proto-oncogene tyrosine-protein kinase Src,p60-Src,pp60c-src,Proto-oncogene c-Src,Src
EIAAB33700 Bos taurus,Bovine,cRaf,Proto-oncogene c-RAF,RAF proto-oncogene serine_threonine-protein kinase,RAF1,Raf-1
EIAAB25168 MOS,Oocyte maturation factor mos,Pig,Proto-oncogene c-Mos,Proto-oncogene serine_threonine-protein kinase mos,Sus scrofa
EIAAB33699 cRaf,Proto-oncogene c-RAF,Raf,RAF proto-oncogene serine_threonine-protein kinase,Raf1,Raf-1,Rat,Rattus norvegicus
U1290m CLIA Mouse,Mus musculus,Myc,Myc proto-oncogene protein,Proto-oncogene c-Myc,Transcription factor p64 96T
EIAAB35722 Mouse,Mus musculus,Proto-oncogene c-Ros-1,Proto-oncogene tyrosine-protein kinase ROS,Ros1,Ros-1
U1290r CLIA Myc,Myc proto-oncogene protein,Proto-oncogene c-Myc,Rat,Rattus norvegicus,Transcription factor p64 96T
EIAAB35719 Proto-oncogene c-Ros-1,Proto-oncogene tyrosine-protein kinase ROS,Rat,Rattus norvegicus,Ros1
EIAAB34305 Mouse,Mus musculus,Proto-oncogene c-Ret,Proto-oncogene tyrosine-protein kinase receptor Ret,Ret
U1290b CLIA Bos taurus,Bovine,MYC,Myc proto-oncogene protein,Proto-oncogene c-Myc,Transcription factor p64 96T
E1290m ELISA kit Mouse,Mus musculus,Myc,Myc proto-oncogene protein,Proto-oncogene c-Myc,Transcription factor p64 96T
E1290b ELISA kit Bos taurus,Bovine,MYC,Myc proto-oncogene protein,Proto-oncogene c-Myc,Transcription factor p64 96T
E1290r ELISA Myc,Myc proto-oncogene protein,Proto-oncogene c-Myc,Rat,Rattus norvegicus,Transcription factor p64 96T
EIAAB39850 p60-Src,pp60c-src,Proto-oncogene c-Src,Proto-oncogene tyrosine-protein kinase Src,Rat,Rattus norvegicus,Src
E1290r ELISA kit Myc,Myc proto-oncogene protein,Proto-oncogene c-Myc,Rat,Rattus norvegicus,Transcription factor p64 96T
E1290m ELISA Mouse,Mus musculus,Myc,Myc proto-oncogene protein,Proto-oncogene c-Myc,Transcription factor p64 96T
EIAAB46412 Homo sapiens,Human,INT4,Proto-oncogene Int-4 homolog,Proto-oncogene Wnt-3,WNT3
E1290b ELISA Bos taurus,Bovine,MYC,Myc proto-oncogene protein,Proto-oncogene c-Myc,Transcription factor p64 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur