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MSP-300 (Fragment)

 Q8I6B6_DROME            Unreviewed;       256 AA.
Q8I6B6;
01-MAR-2003, integrated into UniProtKB/TrEMBL.
01-MAR-2003, sequence version 1.
18-JUL-2018, entry version 87.
SubName: Full=MSP-300 {ECO:0000313|EMBL:AAN62853.1};
Flags: Fragment;
Name=Msp300 {ECO:0000313|FlyBase:FBgn0261836};
Synonyms=Msp-300 {ECO:0000313|EMBL:AAN62853.1};
ORFNames=CG42768 {ECO:0000313|FlyBase:FBgn0261836};
Drosophila melanogaster (Fruit fly).
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
Ephydroidea; Drosophilidae; Drosophila; Sophophora.
NCBI_TaxID=7227 {ECO:0000313|EMBL:AAN62853.1};
[1] {ECO:0000313|EMBL:AAN62853.1}
NUCLEOTIDE SEQUENCE.
PubMed=12408964; DOI=10.1016/S0888-7543(02)96859-X;
Zhang Q., Ragnauth C., Greener M.J., Shanahan C.M., Roberts R.G.;
"The nesprins are giant actin-binding proteins, orthologous to
Drosophila melanogaster muscle protein MSP-300.";
Genomics 80:473-481(2002).
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EMBL; AF521597; AAN62853.1; -; mRNA.
ProteinModelPortal; Q8I6B6; -.
PeptideAtlas; Q8I6B6; -.
PRIDE; Q8I6B6; -.
EnsemblMetazoa; FBtr0332404; FBpp0304677; FBgn0261836.
FlyBase; FBgn0261836; Msp300.
GeneTree; ENSGT00900000140842; -.
OrthoDB; EOG091G0007; -.
ChiTaRS; Msp300; fly.
Bgee; FBgn0261836; -.
ExpressionAtlas; Q8I6B6; baseline and differential.
GO; GO:0005737; C:cytoplasm; IDA:FlyBase.
GO; GO:0005829; C:cytosol; IEA:GOC.
GO; GO:0034993; C:meiotic nuclear membrane microtubule tethering complex; IEA:InterPro.
GO; GO:0005635; C:nuclear envelope; IDA:FlyBase.
GO; GO:0005640; C:nuclear outer membrane; IDA:FlyBase.
GO; GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase.
GO; GO:0030018; C:Z disc; IDA:FlyBase.
GO; GO:0003779; F:actin binding; IDA:FlyBase.
GO; GO:0051015; F:actin filament binding; IEA:InterPro.
GO; GO:0008092; F:cytoskeletal protein binding; ISS:FlyBase.
GO; GO:0019901; F:protein kinase binding; IPI:FlyBase.
GO; GO:0007015; P:actin filament organization; IMP:FlyBase.
GO; GO:0016477; P:cell migration; IMP:FlyBase.
GO; GO:0007303; P:cytoplasmic transport, nurse cell to oocyte; IMP:FlyBase.
GO; GO:0090286; P:cytoskeletal anchoring at nuclear membrane; IEA:InterPro.
GO; GO:0051643; P:endoplasmic reticulum localization; IMP:FlyBase.
GO; GO:0008335; P:female germline ring canal stabilization; IMP:FlyBase.
GO; GO:0060361; P:flight; IMP:FlyBase.
GO; GO:0007523; P:larval visceral muscle development; IMP:FlyBase.
GO; GO:0040011; P:locomotion; IMP:FlyBase.
GO; GO:0007498; P:mesoderm development; NAS:FlyBase.
GO; GO:0034453; P:microtubule anchoring; IGI:FlyBase.
GO; GO:0051646; P:mitochondrion localization; IMP:FlyBase.
GO; GO:0007097; P:nuclear migration; IMP:FlyBase.
GO; GO:0051647; P:nucleus localization; IGI:FlyBase.
GO; GO:0006997; P:nucleus organization; IGI:FlyBase.
GO; GO:0007519; P:skeletal muscle tissue development; IMP:FlyBase.
CDD; cd00014; CH; 2.
Gene3D; 1.10.418.10; -; 2.
InterPro; IPR001589; Actinin_actin-bd_CS.
InterPro; IPR001715; CH-domain.
InterPro; IPR036872; CH_dom_sf.
InterPro; IPR030265; SYNE1.
PANTHER; PTHR44867; PTHR44867; 1.
Pfam; PF00307; CH; 2.
SMART; SM00033; CH; 2.
SUPFAM; SSF47576; SSF47576; 2.
PROSITE; PS00019; ACTININ_1; 1.
PROSITE; PS00020; ACTININ_2; 1.
PROSITE; PS50021; CH; 2.
2: Evidence at transcript level;
Actin-binding {ECO:0000256|SAAS:SAAS00782879};
Repeat {ECO:0000256|SAAS:SAAS00782917}.
DOMAIN 4 111 Calponin-homology (CH).
{ECO:0000259|PROSITE:PS50021}.
DOMAIN 151 256 Calponin-homology (CH).
{ECO:0000259|PROSITE:PS50021}.
NON_TER 1 1 {ECO:0000313|EMBL:AAN62853.1}.
NON_TER 256 256 {ECO:0000313|EMBL:AAN62853.1}.
SEQUENCE 256 AA; 28730 MW; 2AF22CE34A05F3BA CRC64;
EQERVQKKTF TNWINSYLLK RVPPLRIDDL INDLRDGTKL IALLEVLSGE RLPVEKGRVL
RRPHFLSNAN TALQFLASKR IKLVNINPAD LVDGRPPVVL GLIWTIILYF QIEENSRNLE
YLGHGIGGSV SSLDSVGNQK HGDLKAEKWK QGARKTLLNW VTNALPKDSG VEVKDFGASW
RDGVAFLALI DAIKANLVNL AELKKTSNRQ RLETAFDVAE SKLGIAKLLD AEDVDVPKPD
EKSIMTYVAQ FLHKYP


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