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Major outer membrane protein P.IB (PIB) (Protein IB) (Class 3 protein) (Porin)

 OMPB4_NEIMI             Reviewed;         331 AA.
P30689;
01-APR-1993, integrated into UniProtKB/Swiss-Prot.
01-APR-1993, sequence version 1.
23-MAY-2018, entry version 85.
RecName: Full=Major outer membrane protein P.IB;
Short=PIB;
Short=Protein IB;
AltName: Full=Class 3 protein;
AltName: Full=Porin;
Flags: Precursor;
Name=porB;
Neisseria meningitidis serogroup B.
Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales;
Neisseriaceae; Neisseria.
NCBI_TaxID=491;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=CCUG 18243 / S-3032 / Serogroup B / Serotype 12;
PubMed=1330818; DOI=10.1016/0378-1097(92)90644-4;
Ward M.J., Lambden P.R., Heckels J.E.;
"Sequence analysis and relationships between meningococcal class 3
serotype proteins and other porins from pathogenic and non-pathogenic
Neisseria species.";
FEMS Microbiol. Lett. 73:283-289(1992).
-!- FUNCTION: Serves as a slightly cation selective porin.
-!- SUBUNIT: Homotrimer.
-!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane
protein.
-!- SIMILARITY: Belongs to the Gram-negative porin family.
{ECO:0000305}.
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EMBL; X65534; CAA46504.1; -; Genomic_DNA.
PIR; S21406; S21406.
ProteinModelPortal; P30689; -.
SMR; P30689; -.
PRIDE; P30689; -.
GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
CDD; cd00342; gram_neg_porins; 1.
Gene3D; 2.40.160.10; -; 1.
InterPro; IPR033900; Gram_neg_porin_domain.
InterPro; IPR023614; Porin_dom_sf.
InterPro; IPR001702; Porin_Gram-ve.
InterPro; IPR013793; Porin_Gram-ve_CS.
InterPro; IPR002299; Porin_Neis.
Pfam; PF00267; Porin_1; 1.
PRINTS; PR00182; ECOLNEIPORIN.
PRINTS; PR00184; NEISSPPORIN.
PROSITE; PS00576; GRAM_NEG_PORIN; 1.
3: Inferred from homology;
Cell outer membrane; Ion transport; Membrane; Porin; Signal;
Transmembrane; Transmembrane beta strand; Transport.
SIGNAL 1 19
CHAIN 20 331 Major outer membrane protein P.IB.
/FTId=PRO_0000025284.
SEQUENCE 331 AA; 35764 MW; B3AC31A476F126CD CRC64;
MKKSLIALTL AALPVAAMAD VTLYGTIKAG VETSRSVAHN GAQAASVETG TGIVDLGSKI
GFKGQEDLGN GLKAIWQVEQ KASIAGTDSG WGNRQSFIGL KGGFGKLRVG RLNSVLKDTG
DINPWDSKSD YLGVNKIAEP EARLISVRYD SPEFAGLSGS VQYALNDNAG RHNSESYHAG
FNYKNGGFFV QYGGAYKRHH RVQEDINIEK YQIHRLVSGY DNDALHASVA VQQQDAKLVE
ENYSHNSQTE VAATLAYRFG NVTPRVSYAH GFRGLVDSAD YTNDYDQVVV GAEYDFSKRT
SALVSAGWLQ EGKGKNKFVS TAGGVGLRHK F


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