Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)

 KIT_CANLF               Reviewed;         979 AA.
O97799; Q7YRV7; Q8WN23;
30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
05-SEP-2006, sequence version 2.
12-SEP-2018, entry version 161.
RecName: Full=Mast/stem cell growth factor receptor Kit;
Short=SCFR;
EC=2.7.10.1;
AltName: Full=Proto-oncogene c-Kit;
AltName: Full=Tyrosine-protein kinase Kit;
AltName: CD_antigen=CD117;
Flags: Precursor;
Name=KIT;
Canis lupus familiaris (Dog) (Canis familiaris).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
Canis.
NCBI_TaxID=9615;
[1]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
PubMed=9989791; DOI=10.1046/j.1523-1747.1999.00488.x;
Ma Y., Longley B.J., Wang X., Blount J.L., Langley K., Caughey G.H.;
"Clustering of activating mutations in c-KIT's juxtamembrane coding
region in canine mast cell neoplasms.";
J. Invest. Dermatol. 112:165-170(1999).
[2]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
Zemke D., Yuzbasiyan-Gurkan V.;
Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2).
Tsai K.L., Guyon R., Murphy K.E.;
"Characterization of an isoform and RH mapping of canine c-kit.";
Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Tyrosine-protein kinase that acts as cell-surface
receptor for the cytokine KITLG/SCF and plays an essential role in
the regulation of cell survival and proliferation, hematopoiesis,
stem cell maintenance, gametogenesis, mast cell development,
migration and function, and in melanogenesis. In response to
KITLG/SCF binding, KIT can activate several signaling pathways.
Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the
AKT1 signaling pathway by phosphorylation of PIK3R1, the
regulatory subunit of phosphatidylinositol 3-kinase. Activated KIT
also transmits signals via GRB2 and activation of RAS, RAF1 and
the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation
of STAT family members STAT1, STAT3, STAT5A and STAT5B. Activation
of PLCG1 leads to the production of the cellular signaling
molecules diacylglycerol and inositol 1,4,5-trisphosphate. KIT
signaling is modulated by protein phosphatases, and by rapid
internalization and degradation of the receptor. Activated KIT
promotes phosphorylation of the protein phosphatases PTPN6/SHP-1
and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A
and STAT5B. Promotes phosphorylation of PIK3R1, CBL, CRK (isoform
Crk-II), LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, SRC and SHC1
(By similarity). {ECO:0000250}.
-!- CATALYTIC ACTIVITY: ATP + a [protein]-L-tyrosine = ADP + a
[protein]-L-tyrosine phosphate. {ECO:0000255|PROSITE-
ProRule:PRU10028}.
-!- ACTIVITY REGULATION: Present in an inactive conformation in the
absence of bound ligand. KITLG/SCF binding leads to dimerization
and activation by autophosphorylation on tyrosine residues.
Activity is down-regulated by PRKCA-mediated phosphorylation on
serine residues (By similarity). {ECO:0000250}.
-!- SUBUNIT: Monomer in the absence of bound KITLG/SCF. Homodimer in
the presence of bound KITLG/SCF, forming a heterotetramer with two
KITLG/SCF molecules. Interacts (via phosphorylated tyrosine
residues) with the adapter proteins GRB2 and GRB7 (via SH2
domain), and SH2B2/APS. Interacts (via C-terminus) with MPDZ (via
the tenth PDZ domain). Interacts (via phosphorylated tyrosine
residues) with PIK3R1 and PIK3 catalytic subunit. Interacts (via
phosphorylated tyrosine) with CRK (isoform Crk-II), FYN, SHC1 and
MATK/CHK (via SH2 domain). Interacts with LYN and FES/FPS.
Interacts (via phosphorylated tyrosine residues) with the protein
phosphatases PTPN6/SHP-1 (via SH2 domain), PTPN11/SHP-2 (via SH2
domain) and PTPRU. Interacts with PLCG1. Interacts with DOK1 and
TEC. Interacts with IL1RAP (independent of stimulation with
KITLG/SCF). A mast cell-specific KITLG/SCF-induced interleukin-33
signaling complex contains IL1RL1, IL1RAP, KIT and MYD88 (By
similarity). {ECO:0000250|UniProtKB:P05532,
ECO:0000250|UniProtKB:P10721}.
-!- SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane
protein.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=2;
Name=1;
IsoId=O97799-1; Sequence=Displayed;
Name=2;
IsoId=O97799-2; Sequence=VSP_020224;
-!- PTM: Ubiquitinated by SOCS6. KIT is rapidly ubiquitinated after
autophosphorylation induced by KITLG/SCF binding, leading to
internalization and degradation. {ECO:0000250}.
-!- PTM: Autophosphorylated on tyrosine residues. KITLG/SCF binding
promotes autophosphorylation. Phosphorylated tyrosine residues are
important for interaction with specific binding partners (By
similarity). {ECO:0000250}.
-!- MISCELLANEOUS: Numerous proteins are phosphorylated in response to
KIT signaling, but it is not evident to determine which are
directly phosphorylated by KIT under in vivo conditions.
{ECO:0000250}.
-!- SIMILARITY: Belongs to the protein kinase superfamily. Tyr protein
kinase family. CSF-1/PDGF receptor subfamily.
{ECO:0000255|PROSITE-ProRule:PRU00159}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AF044249; AAD02327.1; -; mRNA.
EMBL; AF448148; AAL40833.1; -; mRNA.
EMBL; AY296484; AAP51178.1; -; mRNA.
EMBL; AY313776; AAP76390.1; -; mRNA.
RefSeq; NP_001003181.1; NM_001003181.1.
RefSeq; XP_005628025.1; XM_005627968.2. [O97799-1]
UniGene; Cfa.184; -.
ProteinModelPortal; O97799; -.
SMR; O97799; -.
STRING; 9615.ENSCAFP00000039467; -.
PaxDb; O97799; -.
Ensembl; ENSCAFT00000049830; ENSCAFP00000039467; ENSCAFG00000002065. [O97799-2]
GeneID; 403811; -.
KEGG; cfa:403811; -.
CTD; 3815; -.
VGNC; VGNC:42422; KIT.
eggNOG; KOG0200; Eukaryota.
eggNOG; COG0515; LUCA.
GeneTree; ENSGT00760000118923; -.
HOGENOM; HOG000112008; -.
HOVERGEN; HBG004335; -.
InParanoid; O97799; -.
KO; K05091; -.
OMA; PTFKQIV; -.
OrthoDB; EOG091G01TL; -.
TreeFam; TF325768; -.
BRENDA; 2.7.10.1; 1153.
Reactome; R-CFA-1257604; PIP3 activates AKT signaling.
Reactome; R-CFA-1433557; Signaling by SCF-KIT.
Reactome; R-CFA-1433559; Regulation of KIT signaling.
Reactome; R-CFA-5673001; RAF/MAP kinase cascade.
Reactome; R-CFA-6811558; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling.
Proteomes; UP000002254; Chromosome 13.
Bgee; ENSCAFG00000002065; Expressed in 3 organ(s), highest expression level in prefrontal cortex.
GO; GO:0005911; C:cell-cell junction; IEA:Ensembl.
GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
GO; GO:0005615; C:extracellular space; IEA:Ensembl.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0042629; C:mast cell granule; IEA:GOC.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO; GO:0019955; F:cytokine binding; ISS:UniProtKB.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0002020; F:protease binding; IEA:Ensembl.
GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
GO; GO:0005020; F:stem cell factor receptor activity; IEA:Ensembl.
GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB.
GO; GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.
GO; GO:0000187; P:activation of MAPK activity; ISS:UniProtKB.
GO; GO:0060326; P:cell chemotaxis; ISS:UniProtKB.
GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IEA:Ensembl.
GO; GO:0019221; P:cytokine-mediated signaling pathway; ISS:UniProtKB.
GO; GO:0002371; P:dendritic cell cytokine production; ISS:UniProtKB.
GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; ISS:UniProtKB.
GO; GO:0048565; P:digestive tract development; ISS:UniProtKB.
GO; GO:0035234; P:ectopic germ cell programmed cell death; IEA:Ensembl.
GO; GO:0035162; P:embryonic hemopoiesis; ISS:UniProtKB.
GO; GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
GO; GO:0038162; P:erythropoietin-mediated signaling pathway; ISS:UniProtKB.
GO; GO:0038093; P:Fc receptor signaling pathway; ISS:UniProtKB.
GO; GO:0006687; P:glycosphingolipid metabolic process; IEA:Ensembl.
GO; GO:0035701; P:hematopoietic stem cell migration; IEA:Ensembl.
GO; GO:0002327; P:immature B cell differentiation; ISS:UniProtKB.
GO; GO:0006954; P:inflammatory response; ISS:UniProtKB.
GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
GO; GO:0038109; P:Kit signaling pathway; ISS:UniProtKB.
GO; GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.
GO; GO:0002320; P:lymphoid progenitor cell differentiation; IEA:Ensembl.
GO; GO:0008584; P:male gonad development; IEA:Ensembl.
GO; GO:0002551; P:mast cell chemotaxis; IEA:Ensembl.
GO; GO:0032762; P:mast cell cytokine production; ISS:UniProtKB.
GO; GO:0043303; P:mast cell degranulation; ISS:UniProtKB.
GO; GO:0060374; P:mast cell differentiation; ISS:UniProtKB.
GO; GO:0035855; P:megakaryocyte development; ISS:UniProtKB.
GO; GO:0097326; P:melanocyte adhesion; ISS:UniProtKB.
GO; GO:0030318; P:melanocyte differentiation; ISS:UniProtKB.
GO; GO:0097324; P:melanocyte migration; ISS:UniProtKB.
GO; GO:0002318; P:myeloid progenitor cell differentiation; IEA:Ensembl.
GO; GO:0043069; P:negative regulation of programmed cell death; IEA:Ensembl.
GO; GO:0001541; P:ovarian follicle development; ISS:UniProtKB.
GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
GO; GO:0043473; P:pigmentation; ISS:UniProtKB.
GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
GO; GO:0051091; P:positive regulation of DNA-binding transcription factor activity; IEA:Ensembl.
GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
GO; GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IEA:Ensembl.
GO; GO:1905065; P:positive regulation of vascular smooth muscle cell differentiation; IEA:Ensembl.
GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
GO; GO:0048070; P:regulation of developmental pigmentation; IEA:Ensembl.
GO; GO:0009314; P:response to radiation; IEA:Ensembl.
GO; GO:0007286; P:spermatid development; IEA:Ensembl.
GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
GO; GO:0048863; P:stem cell differentiation; ISS:UniProtKB.
GO; GO:0030217; P:T cell differentiation; ISS:UniProtKB.
Gene3D; 2.60.40.10; -; 5.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003599; Ig_sub.
InterPro; IPR003598; Ig_sub2.
InterPro; IPR013151; Immunoglobulin.
InterPro; IPR011009; Kinase-like_dom_sf.
InterPro; IPR000719; Prot_kinase_dom.
InterPro; IPR017441; Protein_kinase_ATP_BS.
InterPro; IPR027263; SCGF_receptor.
InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
InterPro; IPR008266; Tyr_kinase_AS.
InterPro; IPR020635; Tyr_kinase_cat_dom.
InterPro; IPR001824; Tyr_kinase_rcpt_3_CS.
Pfam; PF00047; ig; 1.
Pfam; PF07714; Pkinase_Tyr; 1.
PIRSF; PIRSF500951; SCGF_recepter; 1.
SMART; SM00409; IG; 4.
SMART; SM00408; IGc2; 2.
SMART; SM00219; TyrKc; 1.
SUPFAM; SSF48726; SSF48726; 3.
SUPFAM; SSF56112; SSF56112; 2.
PROSITE; PS50835; IG_LIKE; 2.
PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PROSITE; PS00240; RECEPTOR_TYR_KIN_III; 1.
2: Evidence at transcript level;
Alternative splicing; ATP-binding; Cell membrane; Complete proteome;
Disulfide bond; Glycoprotein; Immunoglobulin domain; Kinase;
Magnesium; Membrane; Metal-binding; Nucleotide-binding;
Phosphoprotein; Proto-oncogene; Receptor; Reference proteome; Repeat;
Signal; Transferase; Transmembrane; Transmembrane helix;
Tyrosine-protein kinase; Ubl conjugation.
SIGNAL 1 27 {ECO:0000255}.
CHAIN 28 979 Mast/stem cell growth factor receptor
Kit.
/FTId=PRO_0000016751.
TOPO_DOM 28 527 Extracellular. {ECO:0000255}.
TRANSMEM 528 548 Helical. {ECO:0000255}.
TOPO_DOM 549 979 Cytoplasmic. {ECO:0000255}.
DOMAIN 29 114 Ig-like C2-type 1.
DOMAIN 123 207 Ig-like C2-type 2.
DOMAIN 214 311 Ig-like C2-type 3.
DOMAIN 320 413 Ig-like C2-type 4.
DOMAIN 416 510 Ig-like C2-type 5.
DOMAIN 592 940 Protein kinase. {ECO:0000255|PROSITE-
ProRule:PRU00159}.
NP_BIND 599 606 ATP. {ECO:0000255|PROSITE-
ProRule:PRU00159}.
NP_BIND 674 680 ATP. {ECO:0000255|PROSITE-
ProRule:PRU00159}.
REGION 571 573 Important for interaction with
phosphotyrosine-binding proteins.
{ECO:0000250}.
ACT_SITE 795 795 Proton acceptor. {ECO:0000255|PROSITE-
ProRule:PRU00159, ECO:0000255|PROSITE-
ProRule:PRU10028}.
METAL 571 571 Magnesium. {ECO:0000250}.
METAL 800 800 Magnesium. {ECO:0000250}.
METAL 813 813 Magnesium. {ECO:0000250}.
BINDING 626 626 ATP. {ECO:0000255|PROSITE-
ProRule:PRU00159}.
BINDING 799 799 ATP. {ECO:0000255|PROSITE-
ProRule:PRU00159}.
SITE 571 571 Interaction with SH2B2/APS.
{ECO:0000250}.
SITE 939 939 Important for interaction with
phosphotyrosine-binding proteins.
{ECO:0000250}.
SITE 939 939 Interaction with SH2B2/APS.
{ECO:0000250}.
MOD_RES 550 550 Phosphotyrosine; by autocatalysis.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 556 556 Phosphotyrosine; by autocatalysis.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 571 571 Phosphotyrosine; by autocatalysis.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 573 573 Phosphotyrosine; by autocatalysis.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 706 706 Phosphotyrosine; by autocatalysis.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 724 724 Phosphotyrosine; by autocatalysis.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 733 733 Phosphotyrosine; by autocatalysis.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 744 744 Phosphoserine; by PKC/PRKCA.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 749 749 Phosphoserine; by PKC/PRKCA.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 824 824 Phosphoserine.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 826 826 Phosphotyrosine; by autocatalysis.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 894 894 Phosphoserine.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 903 903 Phosphotyrosine; by autocatalysis.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 939 939 Phosphotyrosine; by autocatalysis.
{ECO:0000250|UniProtKB:P10721}.
MOD_RES 962 962 Phosphoserine.
{ECO:0000250|UniProtKB:P10721}.
CARBOHYD 96 96 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 132 132 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 147 147 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 286 286 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 296 296 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 303 303 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 355 355 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 370 370 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 403 403 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 466 466 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 489 489 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 60 99 {ECO:0000255|PROSITE-ProRule:PRU00114}.
DISULFID 138 188 {ECO:0000255|PROSITE-ProRule:PRU00114}.
DISULFID 153 185 {ECO:0000255|PROSITE-ProRule:PRU00114}.
DISULFID 235 293 {ECO:0000255|PROSITE-ProRule:PRU00114}.
DISULFID 431 494 {ECO:0000255|PROSITE-ProRule:PRU00114}.
VAR_SEQ 512 515 Missing (in isoform 2).
{ECO:0000303|PubMed:9989791,
ECO:0000303|Ref.3}.
/FTId=VSP_020224.
CONFLICT 23 23 Q -> R (in Ref. 1; AAD02327).
{ECO:0000305}.
CONFLICT 332 332 E -> Q (in Ref. 1; AAD02327).
{ECO:0000305}.
CONFLICT 442 442 D -> G (in Ref. 1; AAD02327).
{ECO:0000305}.
SEQUENCE 979 AA; 109753 MW; 46C30D5DEB8E33D3 CRC64;
MRGARGAWDF LCVLLLLLLL GVQTGSSQPS VSPGEPSLPS IHPAKSELIV SVGDELRLSC
TDPGFVKWTF ETLGQLNENT HNEWITEKAE AGHTGNYTCT NRDGLSRSIY VFVRDPAKLF
LVDLPLYGKE GNDTLVRCPL TDPEVTNYSL RGCEGKPLPK DLTFVADPKA GITIRNVKRE
YHRLCLHCSA DQKGRTVLSK KFTLKVRAAI RAVPVVSVSK TSSLLKEGEA FSVMCFIKDV
SSFVDSMWIK ENSQQTNAQT QSNSWHHGDF NFERQEKLII SSARVNDSGV FMCYANNTFG
SANVTTTLEV VDKGFINIFP MMSTTIFVND GENVDLIVEY EAYPKPEHQQ WIYMNRTFTD
KWEDYPKSDN ESNIRYVSEL HLTRLKGNEG GTYTFQVSNS DVNSSVTFNV YVNTKPEILT
HESLTNGMLQ CVVAGFPEPA VDWYFCPGAE QRCSVPIGPM DVQMQNSSLS PSGKLVVQSS
IDYSAFKHNG TVECRAYNNV GRSSAFFNFA FKGNSKEQIH PHTLFTPLLI GFVIAAGMMC
IIVMILTYKY LQKPMYEVQW KVVEEINGNN YVYIDPTQLP YDHKWEFPRN RLSFGKTLGA
GAFGKVVEAT AYGLIKSDAA MTVAVKMLKP SAHLTEREAL MSELKVLSYL GNHMNIVNLL
GACTVGGPTL VITEYCCYGD LLNFLRRKRD SFICSKQEDH GEVALYKNLL HSKESSCSDS
TNEYMDMKPG VSYVVPTKAD KRRSARIGSY IERDVTPAIM EDDELALDLE DLLSFSYQVA
KGMAFLASKN CIHRDLAARN ILLTHGRITK ICDFGLARDI KNDSNYVVKG NARLPVKWMA
PESIFNCVYT FESDVWSYGI FLWELFSLGS SPYPGMPVDS KFYKMIKEGF RMLSPEHAPA
EMYDIMKTCW DADPLKRPTF KQIVQLIEKQ ISDSTNHIYS NLANCSPNPE RPVVDHSVRI
NSVGSSASST QPLLVHEDV


Related products :

Catalog number Product name Quantity
15-288-21114 Mast_stem cell growth factor receptor - EC 2.7.10.1; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117 antigen Polyclonal 0.05 mg
15-288-21114 Mast_stem cell growth factor receptor - EC 2.7.10.1; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117 antigen Polyclonal 0.1 mg
U0121h CLIA Homo sapiens,Human,KIT,Mast_stem cell growth factor receptor Kit,p145 c-kit,PBT,Piebald trait protein,Proto-oncogene c-Kit,SCFR,SCFR,Tyrosine-protein kinase Kit,v-kit Hardy-Zuckerman 4 feline sar 96T
E0121h ELISA kit Homo sapiens,Human,KIT,Mast_stem cell growth factor receptor Kit,p145 c-kit,PBT,Piebald trait protein,Proto-oncogene c-Kit,SCFR,SCFR,Tyrosine-protein kinase Kit,v-kit Hardy-Zuckerman 4 feli 96T
E0121h ELISA Homo sapiens,Human,KIT,Mast_stem cell growth factor receptor Kit,p145 c-kit,PBT,Piebald trait protein,Proto-oncogene c-Kit,SCFR,SCFR,Tyrosine-protein kinase Kit,v-kit Hardy-Zuckerman 4 feline sa 96T
U0121p CLIA KIT,Mast_stem cell growth factor receptor Kit,Pig,Proto-oncogene c-Kit,SCFR,Sus scrofa,Tyrosine-protein kinase Kit 96T
E0121p ELISA kit KIT,Mast_stem cell growth factor receptor Kit,Pig,Proto-oncogene c-Kit,SCFR,Sus scrofa,Tyrosine-protein kinase Kit 96T
E0121p ELISA KIT,Mast_stem cell growth factor receptor Kit,Pig,Proto-oncogene c-Kit,SCFR,Sus scrofa,Tyrosine-protein kinase Kit 96T
E0121b ELISA Bos taurus,Bovine,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
U0121b CLIA Bos taurus,Bovine,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
U0121m CLIA Kit,Mast_stem cell growth factor receptor Kit,Mouse,Mus musculus,Proto-oncogene c-Kit,SCFR,Sl,Tyrosine-protein kinase Kit 96T
E0121m ELISA kit Kit,Mast_stem cell growth factor receptor Kit,Mouse,Mus musculus,Proto-oncogene c-Kit,SCFR,Sl,Tyrosine-protein kinase Kit 96T
E0121b ELISA kit Bos taurus,Bovine,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
E0121m ELISA Kit,Mast_stem cell growth factor receptor Kit,Mouse,Mus musculus,Proto-oncogene c-Kit,SCFR,Sl,Tyrosine-protein kinase Kit 96T
10-054-165009 cKit HUMAN - EC 2.7.10.1; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117 antigen 0.01 mg
U0121c CLIA Chicken,Gallus gallus,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
E0121c ELISA kit Chicken,Gallus gallus,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
E0121c ELISA Chicken,Gallus gallus,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
18-785-210252 c-Kit (Phospho-Tyr721) - EC 2.7.10.1; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117 antigen Polyclonal 0.05 mg
18-785-210252 c-Kit (Phospho-Tyr721) - EC 2.7.10.1; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117 antigen Polyclonal 0.1 mg
32-138 C-kit (CD117,145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c 0.1 mL
U0121c CLIA Canis familiaris,Canis lupus familiaris,Dog,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
E0121c ELISA kit Canis familiaris,Canis lupus familiaris,Dog,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
E0121c ELISA Canis familiaris,Canis lupus familiaris,Dog,KIT,Mast_stem cell growth factor receptor Kit,Proto-oncogene c-Kit,SCFR,Tyrosine-protein kinase Kit 96T
20-272-190432 c - Kit - Mouse monoclonal [104D2] to c - Kit; EC 2.7.10.1; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117 antigen Monoclonal 0.05 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur