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Mem2

 L8F5U5_MYCSE            Unreviewed;       485 AA.
L8F5U5;
03-APR-2013, integrated into UniProtKB/TrEMBL.
03-APR-2013, sequence version 1.
25-OCT-2017, entry version 24.
SubName: Full=Mem2 {ECO:0000313|EMBL:ELQ86714.1};
Name=mem2 {ECO:0000313|EMBL:ELQ86714.1};
ORFNames=D806_5747 {ECO:0000313|EMBL:ELQ86714.1};
Mycobacterium smegmatis (strain MKD8).
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
Mycobacterium.
NCBI_TaxID=1214915 {ECO:0000313|EMBL:ELQ86714.1, ECO:0000313|Proteomes:UP000011200};
[1] {ECO:0000313|EMBL:ELQ86714.1, ECO:0000313|Proteomes:UP000011200}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MKD8 {ECO:0000313|EMBL:ELQ86714.1,
ECO:0000313|Proteomes:UP000011200};
PubMed=23618714; DOI=10.1128/genomeA.00148-13;
Gray T.A., Palumbo M.J., Derbyshire K.M.;
"Draft genome sequence of MKD8, a conjugal recipient Mycobacterium
smegmatis strain.";
Genome Announc. 1:E0014813-E0014813(2013).
-!- SIMILARITY: Belongs to the major facilitator superfamily.
{ECO:0000256|SAAS:SAAS00769108}.
-!- CAUTION: The sequence shown here is derived from an
EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
preliminary data. {ECO:0000313|EMBL:ELQ86714.1}.
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EMBL; AOCJ01000091; ELQ86714.1; -; Genomic_DNA.
RefSeq; WP_003897083.1; NZ_CM001762.1.
EnsemblBacteria; ELQ86714; ELQ86714; D806_5747.
PATRIC; fig|1214915.3.peg.5774; -.
OrthoDB; POG091H0CG8; -.
Proteomes; UP000011200; Chromosome.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
GO; GO:0005215; F:transporter activity; IEA:InterPro.
GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
CDD; cd06174; MFS; 1.
InterPro; IPR004638; Drug-R_transpt_efflux_EmrB.
InterPro; IPR011701; MFS.
InterPro; IPR020846; MFS_dom.
InterPro; IPR036259; MFS_trans_sf.
InterPro; IPR005829; Sugar_transporter_CS.
Pfam; PF07690; MFS_1; 1.
SUPFAM; SSF103473; SSF103473; 2.
TIGRFAMs; TIGR00711; efflux_EmrB; 1.
PROSITE; PS50850; MFS; 1.
PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
3: Inferred from homology;
Cell membrane {ECO:0000256|SAAS:SAAS00769078};
Complete proteome {ECO:0000313|Proteomes:UP000011200};
Membrane {ECO:0000256|SAAS:SAAS00769070,
ECO:0000256|SAAS:SAAS00769078, ECO:0000256|SAM:Phobius};
Transmembrane {ECO:0000256|SAAS:SAAS00769070,
ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
TRANSMEM 52 70 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 82 101 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 107 132 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 144 167 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 173 192 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 204 222 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 234 251 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 272 295 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 301 323 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 335 354 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 360 386 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 407 426 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 438 462 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 16 461 MFS. {ECO:0000259|PROSITE:PS50850}.
SEQUENCE 485 AA; 50881 MW; 9621BCE35032F4F2 CRC64;
MNETVGALSA RRKAIILVSC CLSLLIVSMD ATIVNVAIPS IRSDLGASPS QLQWVIDVYT
LVLASLLLLA GATADRFGRR RTFHLGLTVF AVASLLCSVA PNIETLIAAR LLQAIGGSML
NPVAMSIITQ VFTGRVERAR AIGVWGSVVG ISMALGPLVG GALIEYVDWR AVFWINLPIC
ALAILLTAIF VRESKSSTMR DVDPVGQGLG VAFLFGVVFV LIEGPGMGWT DPRTLAVAAT
ALVAFLAFLR YESRRHDPFI DLRFFRSVPF ASATLVAVCA FAAYGAFLFM MSLYLQSERG
YSAMFTGLIY LPIAIGALIF SPLSGRMVGR FGSRPSLVSA GILITAATVM LAQMTATTPV
WLLLVIFAVF GIGFALVNAP ITTAAVSGMP LDRAGAASAV ASTSRQVGVS IGVALCGSVA
GTALAGTGVD FAAASRPLWL ICTALGVVIV AIGIVSTSPW ALRSAERLAP LIGQHHRPAE
VAHAR


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