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Membrane protein-like protein (Similar to Teicoplanin resistance associated membrane protein TcaA) (Teicoplanin resistance associated membrane protein TcaA-like protein)

 O87355_STAAU            Unreviewed;       423 AA.
O87355;
01-NOV-1998, integrated into UniProtKB/TrEMBL.
01-NOV-1998, sequence version 1.
22-NOV-2017, entry version 78.
SubName: Full=Membrane protein-like protein {ECO:0000313|EMBL:CXO33727.1};
SubName: Full=Similar to Teicoplanin resistance associated membrane protein TcaA {ECO:0000313|EMBL:ADA61318.1};
SubName: Full=Teicoplanin resistance associated membrane protein TcaA-like protein {ECO:0000313|EMBL:ACZ68655.1};
Name=tcaA_2 {ECO:0000313|EMBL:CXO33727.1};
ORFNames=BN1321_460014 {ECO:0000313|EMBL:CRI20892.1},
ERS072840_02807 {ECO:0000313|EMBL:CXO33727.1},
PGO1_p02 {ECO:0000313|EMBL:CAR62399.1},
SAP014A_011 {ECO:0000313|EMBL:ADA61318.1},
SAP068A_020 {ECO:0000313|EMBL:ACZ68655.1},
SAP069A_040 {ECO:0000313|EMBL:ACZ68730.1},
SAP079A_013 {ECO:0000313|EMBL:ADA62083.1},
SAP082A_032 {ECO:0000313|EMBL:ADA62204.1},
VRA0045 {ECO:0000313|EMBL:AAQ17165.1};
Staphylococcus aureus.
Plasmid SAP014A {ECO:0000313|EMBL:ADA61318.1},
Plasmid SAP068A {ECO:0000313|EMBL:ACZ68655.1},
Plasmid SAP069A {ECO:0000313|EMBL:ACZ68730.1},
Plasmid SAP079A {ECO:0000313|EMBL:ADA62083.1},
Plasmid SAP082A {ECO:0000313|EMBL:ADA62204.1},
Plasmid pGO1 {ECO:0000313|EMBL:CAR62399.1},
Plasmid pLW043 {ECO:0000313|EMBL:AAQ17165.1}, and
Plasmid pSK41 {ECO:0000313|EMBL:AAC61932.1}.
Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
Staphylococcus.
NCBI_TaxID=1280 {ECO:0000313|EMBL:AAC61932.1};
[1] {ECO:0000313|EMBL:AAC61932.1}
NUCLEOTIDE SEQUENCE.
PLASMID=pSK41 {ECO:0000313|EMBL:AAC61932.1};
PubMed=9721269;
Berg T., Firth N., Apisiridej S., Hettiaratchi A., Leelaporn A.,
Skurray R.A.;
"Complete nucleotide sequence of pSK41: evolution of staphylococcal
conjugative multiresistance plasmids.";
J. Bacteriol. 180:4350-4359(1998).
[2] {ECO:0000313|EMBL:AAQ17165.1}
NUCLEOTIDE SEQUENCE.
PLASMID=pLW043 {ECO:0000313|EMBL:AAQ17165.1};
PubMed=14645850; DOI=10.1126/science.1090956;
Weigel L.M., Clewell D.B., Gill S.R., Clark N.C., McDougal L.K.,
Flannagan S.E., Kolonay J.F., Shetty J., Killgore G.E., Tenover F.C.;
"Genetic analysis of a high-level vancomycin-resistant isolate of
Staphylococcus aureus.";
Science 302:1569-1571(2003).
[3] {ECO:0000313|EMBL:AAQ17165.1}
NUCLEOTIDE SEQUENCE.
PLASMID=pLW043 {ECO:0000313|EMBL:AAQ17165.1};
Gill S., Kolonay J., Shetty J., Tenover F., Weigel L.;
Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
[4] {ECO:0000313|EMBL:CAR62399.1}
NUCLEOTIDE SEQUENCE.
PLASMID=pGO1 {ECO:0000313|EMBL:CAR62399.1};
PubMed=19298835; DOI=10.1016/j.plasmid.2009.03.001;
Caryl J.A., O'Neill A.J.;
"Complete nucleotide sequence of pGO1, the prototype conjugative
plasmid from the Staphylococci.";
Plasmid 62:35-38(2009).
[5] {ECO:0000313|EMBL:ACZ68655.1}
NUCLEOTIDE SEQUENCE.
STRAIN=CDC58 {ECO:0000313|EMBL:ADA61318.1},
CDCGA672 {ECO:0000313|EMBL:ADA62083.1},
CDCPANICU {ECO:0000313|EMBL:ADA62204.1},
PM64 {ECO:0000313|EMBL:ACZ68655.1}, and
PM79 {ECO:0000313|EMBL:ACZ68730.1};
PLASMID=SAP014A {ECO:0000313|EMBL:ADA61318.1},
SAP068A {ECO:0000313|EMBL:ACZ68655.1},
SAP069A {ECO:0000313|EMBL:ACZ68730.1},
SAP079A {ECO:0000313|EMBL:ADA62083.1}, and
SAP082A {ECO:0000313|EMBL:ADA62204.1};
Gill J., Borman J., Shetty J., Hostetler J., Durkin S., Montgomery B.;
Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
[6] {ECO:0000313|EMBL:ACZ68655.1}
NUCLEOTIDE SEQUENCE.
STRAIN=CDC58 {ECO:0000313|EMBL:ADA61318.1},
PM64 {ECO:0000313|EMBL:ACZ68655.1}, and
PM79 {ECO:0000313|EMBL:ACZ68730.1};
PLASMID=SAP014A {ECO:0000313|EMBL:ADA61318.1},
SAP068A {ECO:0000313|EMBL:ACZ68655.1}, and
SAP069A {ECO:0000313|EMBL:ACZ68730.1};
Summers A.O., Shearer J., Wireman J.;
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
[7] {ECO:0000313|EMBL:ADA62083.1}
NUCLEOTIDE SEQUENCE.
STRAIN=CDCGA672 {ECO:0000313|EMBL:ADA62083.1}, and
CDCPANICU {ECO:0000313|EMBL:ADA62204.1};
PLASMID=SAP079A {ECO:0000313|EMBL:ADA62083.1}, and
SAP082A {ECO:0000313|EMBL:ADA62204.1};
PubMed=20585117; DOI=10.1128/AAC.00351-10;
McDougal L.K., Fosheim G.E., Nicholson A., Bulens S.N., Limbago B.M.,
Shearer J.E., Summers A.O., Patel J.B.;
"Emergence of resistance among USA300 methicillin-resistant
Staphylococcus aureus isolates causing invasive disease in the United
States.";
Antimicrob. Agents Chemother. 54:3804-3811(2010).
[8] {ECO:0000313|EMBL:CRI20892.1, ECO:0000313|Proteomes:UP000039437}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AH1 {ECO:0000313|EMBL:CRI20892.1,
ECO:0000313|Proteomes:UP000039437};
Syromyatnikov M.Y., Popov V.N.;
Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
[9] {ECO:0000313|EMBL:CXO33727.1, ECO:0000313|Proteomes:UP000069800}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=St308 {ECO:0000313|EMBL:CXO33727.1}, and
st308 {ECO:0000313|Proteomes:UP000069800};
Pathogen Informatics;
Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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EMBL; AF051917; AAC61932.1; -; Genomic_DNA.
EMBL; AE017171; AAQ17165.1; -; Genomic_DNA.
EMBL; GQ900421; ACZ68655.1; -; Genomic_DNA.
EMBL; GQ900422; ACZ68730.1; -; Genomic_DNA.
EMBL; GQ900379; ADA61318.1; -; Genomic_DNA.
EMBL; GQ900432; ADA62083.1; -; Genomic_DNA.
EMBL; GQ900434; ADA62204.1; -; Genomic_DNA.
EMBL; FM207042; CAR62399.1; -; Genomic_DNA.
EMBL; CVOQ01000041; CRI20892.1; -; Genomic_DNA.
EMBL; FGEC01000034; CXO33727.1; -; Genomic_DNA.
RefSeq; NP_863603.1; NC_005024.1.
RefSeq; NP_878021.1; NC_005054.1.
RefSeq; WP_000386736.1; NZ_NKCQ01000124.1.
RefSeq; YP_002790898.1; NC_012547.1.
RefSeq; YP_006937631.1; NC_013320.1.
RefSeq; YP_006938321.1; NC_013338.1.
RefSeq; YP_006938395.1; NC_013339.1.
RefSeq; YP_006938476.1; NC_013342.1.
RefSeq; YP_006938597.1; NC_013344.1.
EnsemblBacteria; CRI20892; CRI20892; BN1321_460014.
EnsemblBacteria; CXO33727; CXO33727; ERS072840_02807.
GeneID; 13874781; -.
GeneID; 13875517; -.
GeneID; 13875564; -.
GeneID; 13875647; -.
GeneID; 13875770; -.
GeneID; 2598285; -.
GeneID; 31595207; -.
GeneID; 4267507; -.
GeneID; 7751494; -.
PATRIC; fig|1280.3364.peg.1718; -.
eggNOG; COG4640; LUCA.
Proteomes; UP000039437; Unassembled WGS sequence.
Proteomes; UP000069800; Unassembled WGS sequence.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
InterPro; IPR023599; Mem_prot_TcaA.
PIRSF; PIRSF032522; TcaA; 1.
4: Predicted;
Coiled coil {ECO:0000256|SAM:Coils};
Complete proteome {ECO:0000313|Proteomes:UP000039437,
ECO:0000313|Proteomes:UP000069800};
Membrane {ECO:0000256|SAM:Phobius};
Plasmid {ECO:0000313|EMBL:AAC61932.1};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
TRANSMEM 12 31 Helical. {ECO:0000256|SAM:Phobius}.
COILED 77 104 {ECO:0000256|SAM:Coils}.
COILED 302 340 {ECO:0000256|SAM:Coils}.
SEQUENCE 423 AA; 49635 MW; 27C9873BF96A1115 CRC64;
MDYTNQKRKY IIFGIVLAIT LLIVGIAYYL ISLNNAKGQV KEFEKLVQHN DYNSIAKKLS
NKEETLSEND AKNFVLFVKS KENQEQYNEQ IQKIKSNIDK NKDNNTVYGS ITDQYGNNLI
TIKKNGKTFF FIDKLEFKPK LTSVYVKEFN NTGIYKYQQE NAKKVIAESN QTTELGKFFI
GKYSIKTDKT IEDSIHNGTL TGKIDIDLSN RGNNNKIYAD EDFNQSWFKV KLNNDSLLEK
NSYKLLIDDK DVDYNSKKTY GKYYNPTELS VYAIGKLEGK EFKTNRINIR RNYDNKPQNL
KLSFKESQIR DYESKSKKVK EKAKSYIKEY TKELNKAYKK KDYKYISDYV KNNSQLEKQL
KKQVKSKSKV KFKDVKINNV KRDKNKIYIE LSKTNNGNVF QTKYTLDYDN VSNEFLVEDS
HDN


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