Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Methionine-R-sulfoxide reductase B1 (MsrB1) (EC 1.8.4.-) (Selenoprotein X) (SelX)

 MSRB1_PONAB             Reviewed;         116 AA.
Q5R869;
19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
26-FEB-2008, sequence version 2.
22-NOV-2017, entry version 67.
RecName: Full=Methionine-R-sulfoxide reductase B1;
Short=MsrB1;
EC=1.8.4.12 {ECO:0000250|UniProtKB:Q9JLC3};
EC=1.8.4.14 {ECO:0000250|UniProtKB:Q9JLC3};
AltName: Full=Selenoprotein X;
Short=SelX;
Name=MSRB1; Synonyms=SEPX1;
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Pongo.
NCBI_TaxID=9601;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Kidney;
The German cDNA consortium;
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Methionine-sulfoxide reductase that specifically reduces
methionine (R)-sulfoxide back to methionine. While in many cases,
methionine oxidation is the result of random oxidation following
oxidative stress, methionine oxidation is also a post-
translational modification that takes place on specific residue.
Acts as a regulator of actin assembly by reducing methionine (R)-
sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin,
thereby promoting filament repolymerization. Plays a role in
innate immunity by reducing oxidized actin, leading to actin
repolymerization in macrophages. {ECO:0000250|UniProtKB:Q9JLC3}.
-!- CATALYTIC ACTIVITY: Peptide-L-methionine + thioredoxin disulfide +
H(2)O = peptide-L-methionine (R)-S-oxide + thioredoxin.
{ECO:0000250|UniProtKB:Q9JLC3}.
-!- CATALYTIC ACTIVITY: L-methionine + thioredoxin disulfide + H(2)O =
L-methionine (R)-S-oxide + thioredoxin.
{ECO:0000250|UniProtKB:Q9JLC3}.
-!- COFACTOR:
Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
Evidence={ECO:0000250|UniProtKB:Q9JLC3};
Note=Binds 1 zinc ion per subunit. {ECO:0000250|UniProtKB:Q9JLC3};
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus
{ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
-!- SIMILARITY: Belongs to the MsrB Met sulfoxide reductase family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; CR859820; CAH91977.1; -; mRNA.
EMBL; CR859885; CAH92041.1; -; mRNA.
RefSeq; NP_001126146.1; NM_001132674.1.
UniGene; Pab.11564; -.
STRING; 9601.ENSPPYP00000007893; -.
GeneID; 100173105; -.
KEGG; pon:100173105; -.
CTD; 51734; -.
eggNOG; KOG0856; Eukaryota.
eggNOG; COG0229; LUCA.
HOVERGEN; HBG002192; -.
InParanoid; Q5R869; -.
KO; K07305; -.
Proteomes; UP000001595; Unplaced.
GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0003779; F:actin binding; ISS:UniProtKB.
GO; GO:0033745; F:L-methionine-(R)-S-oxide reductase activity; IEA:UniProtKB-EC.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0033743; F:peptide-methionine (R)-S-oxide reductase activity; ISS:UniProtKB.
GO; GO:0030041; P:actin filament polymerization; ISS:UniProtKB.
GO; GO:0045087; P:innate immune response; ISS:UniProtKB.
GO; GO:0030091; P:protein repair; IEA:InterPro.
GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
InterPro; IPR028427; Met_Sox_Rdtase.
InterPro; IPR002579; Met_Sox_Rdtase_MsrB.
InterPro; IPR011057; Mss4-like_sf.
PANTHER; PTHR10173; PTHR10173; 1.
Pfam; PF01641; SelR; 1.
SUPFAM; SSF51316; SSF51316; 1.
PROSITE; PS51790; MSRB; 1.
3: Inferred from homology;
Complete proteome; Cytoplasm; Cytoskeleton; Immunity; Innate immunity;
Metal-binding; Nucleus; Oxidoreductase; Reference proteome;
Selenocysteine; Zinc.
CHAIN 1 116 Methionine-R-sulfoxide reductase B1.
/FTId=PRO_0000249713.
DOMAIN 1 106 MsrB. {ECO:0000255|PROSITE-
ProRule:PRU01126}.
ACT_SITE 95 95 Nucleophile. {ECO:0000255|PROSITE-
ProRule:PRU01126}.
METAL 23 23 Zinc. {ECO:0000255|PROSITE-
ProRule:PRU01126}.
METAL 26 26 Zinc. {ECO:0000255|PROSITE-
ProRule:PRU01126}.
METAL 71 71 Zinc. {ECO:0000255|PROSITE-
ProRule:PRU01126}.
METAL 74 74 Zinc. {ECO:0000255|PROSITE-
ProRule:PRU01126}.
NON_STD 95 95 Selenocysteine. {ECO:0000250}.
SEQUENCE 116 AA; 12744 MW; 032B033BFFCB7C11 CRC64;
MSFCSFFGGE VFQNHFEPGV YVCAKCGYEL FSSRSKYAHS SPWPAFTETI HADSVAKRPE
HNRAEALKVS CGKCGNGLGH EFLNDGPKPG QSRFUIFSSS LKFVPKGKET SASQGH


Related products :

Catalog number Product name Quantity
EIAAB25532 Methionine-R-sulfoxide reductase B1,Mouse,MsrB1,Msrb1,Mus musculus,Selenoprotein R,Selenoprotein X,SelR,SelX,Sepr,Sepx1
EIAAB25531 Methionine-R-sulfoxide reductase B1,MsrB1,MSRB1,Pig,Selenoprotein X,SelX,SEPX1,Sus scrofa
EIAAB25535 Methionine-R-sulfoxide reductase B1,MsrB1,Msrb1,Rat,Rattus norvegicus,Selenoprotein X,SelX,Sepx1
EIAAB25534 Bos taurus,Bovine,Methionine-R-sulfoxide reductase B1,MsrB1,MSRB1,Selenoprotein X,SelX,SEPX1
EIAAB25533 Homo sapiens,HSPC270,Human,Methionine-R-sulfoxide reductase B1,MsrB1,MSRB1,Selenoprotein X,SelX,SEPX1
LF-MA0084 anti-Methionine Sulfoxide Reductase A , Mouse monoclonal to Methionine Sulfoxide Reductase A, Isotype IgG2b, Host Mouse 100 ul
LF-MA0083 anti-Methionine Sulfoxide Reductase A , Mouse monoclonal to Methionine Sulfoxide Reductase A, Isotype IgG1, Host Mouse 100 ul
LF-PA0088 anti-Methionine sulfoxide reductase B , Rabbit polyclonal to Methionine sulfoxide reductase B , Isotype IgG, Host Rabbit 100 ul
LF-PA0031 anti-Methionine Sulfoxide Reductase A , Rabbit polyclonal to Methionine Sulfoxide Reductase A , Isotype IgG, Host Rabbit 100 ul
LF-PA10011 anti-Methionine Sulfoxide Reductase A , Mouse polyclonal to Methionine Sulfoxide Reductase A , Isotype , Host Mouse 50 uL
LF-PA10012 anti-Methionine Sulfoxide Reductase A , Rabbit polyclonal to Methionine Sulfoxide Reductase A , Isotype , Host Rabbit 100 ug
EIAAB25528 Homo sapiens,Human,Mitochondrial peptide methionine sulfoxide reductase,MSRA,Peptide Met(O) reductase,Peptide-methionine (S)-S-oxide reductase,PMSR,Protein-methionine-S-oxide reductase
EIAAB25530 Mitochondrial peptide methionine sulfoxide reductase,Mouse,Msra,Mus musculus,Peptide Met(O) reductase,Peptide-methionine (S)-S-oxide reductase,PMSR,Protein-methionine-S-oxide reductase
EIAAB25529 Mitochondrial peptide methionine sulfoxide reductase,Msra,Peptide Met(O) reductase,Peptide-methionine (S)-S-oxide reductase,PMSR,Protein-methionine-S-oxide reductase,Rat,Rattus norvegicus
EIAAB25527 Bos taurus,Bovine,Mitochondrial peptide methionine sulfoxide reductase,MSRA,Peptide Met(O) reductase,Peptide-methionine (S)-S-oxide reductase,Protein-methionine-S-oxide reductase
PC-569 Methionine Sulfoxide Reductase B 100 uL
PC-568 Methionine Sulfoxide Reductase A 100 uL
MC-1034 Methionine Sulfoxide Reductase A 100 uL
PC-568 Methionine Sulfoxide Reductase A Poly 100 uL
PC-569 Methionine Sulfoxide Reductase B Poly 100 uL
MC-1034 Methionine Sulfoxide Reductase A 100 uL
MC-1034 Methionine Sulfoxide Reductase A 5B5 100 uL
enz-124 Recombinant E.Coli Methionine Sulfoxide Reductase B 1mg
YF-MA11522 anti-Methionine Sulfoxide Reductase B (8B2) 100 ug
enz-621 Recombinant Human Methionine Sulfoxide Reductase A 1mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur