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Microtubule associated-protein orbit

 A0A1S4FA56_AEDAE        Unreviewed;      1506 AA.
A0A1S4FA56;
12-APR-2017, integrated into UniProtKB/TrEMBL.
12-APR-2017, sequence version 1.
27-SEP-2017, entry version 5.
SubName: Full=Microtubule associated-protein orbit {ECO:0000313|VectorBase:AAEL005211-PA};
Name=5566106 {ECO:0000313|VectorBase:AAEL005211-PA};
Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
Culicidae; Culicinae; Aedini; Aedes; Stegomyia.
NCBI_TaxID=7159 {ECO:0000313|VectorBase:AAEL005211-PA};
[1] {ECO:0000313|VectorBase:AAEL005211-PA}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Liverpool/LVPib12 {ECO:0000313|VectorBase:AAEL005211-PA};
PubMed=17510324; DOI=10.1126/science.1138878;
Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M.,
Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J.,
Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P.,
Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V.,
Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B.,
DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M.,
Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H.,
Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S.,
Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D.,
Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A.,
Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D.,
White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A.,
Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J.,
Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B.,
Fraser-Liggett C.M., Severson D.W.;
"Genome sequence of Aedes aegypti, a major arbovirus vector.";
Science 316:1718-1723(2007).
[2] {ECO:0000313|VectorBase:AAEL005211-PA}
IDENTIFICATION.
STRAIN=Liverpool/LVPib12 {ECO:0000313|VectorBase:AAEL005211-PA};
VectorBase;
Submitted (FEB-2017) to UniProtKB.
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EnsemblMetazoa; AAEL005211-RA; AAEL005211-PA; AAEL005211.
VectorBase; AAEL005211-RA; AAEL005211-PA; AAEL005211.
GO; GO:0005881; C:cytoplasmic microtubule; IEA:InterPro.
GO; GO:0005828; C:kinetochore microtubule; IEA:InterPro.
GO; GO:0043515; F:kinetochore binding; IEA:InterPro.
GO; GO:0051010; F:microtubule plus-end binding; IEA:InterPro.
Gene3D; 1.25.10.10; -; 4.
InterPro; IPR011989; ARM-like.
InterPro; IPR016024; ARM-type_fold.
InterPro; IPR028399; CLASP_1.
InterPro; IPR024395; CLASP_N_dom.
InterPro; IPR021133; HEAT_type_2.
InterPro; IPR034085; TOG.
PANTHER; PTHR21567:SF49; PTHR21567:SF49; 1.
Pfam; PF12348; CLASP_N; 2.
SMART; SM01349; TOG; 4.
SUPFAM; SSF48371; SSF48371; 4.
PROSITE; PS50077; HEAT_REPEAT; 1.
4: Predicted;
DOMAIN 2 232 TOG. {ECO:0000259|SMART:SM01349}.
DOMAIN 304 538 TOG. {ECO:0000259|SMART:SM01349}.
DOMAIN 867 1105 TOG. {ECO:0000259|SMART:SM01349}.
DOMAIN 1277 1504 TOG. {ECO:0000259|SMART:SM01349}.
REPEAT 1440 1478 HEAT. {ECO:0000256|PROSITE-
ProRule:PRU00103}.
SEQUENCE 1506 AA; 167816 MW; 1BFCA7D863F57F42 CRC64;
MAYHKPTDID GFITQMAKAD MRVKAQLAED LVLYLNDSEN SIECVDLGLL IDGLIPWMIG
SHFKIAQRAL EAFTELIVRL GQDFNAYTST ILPHVVDRLG DSRDTVREKA QLLLHKLMEC
RVVSPQSLLD KLTVCFKHKN AKVREEFLQT IVNALNEYGT QSLSVKTYIQ PIVLLLGDPA
PTVRDAAVQT LVEIYKHVGD KLRIDLRKRD VPAAKFIILE QKFDETKNDG LLLPSAISSA
NTNDDVDNAI VARPTRLVKR TPSATPRKPL FETQGSGDLL AAGAVSVEIF ENSFENVPQL
TIFSQRDMDE HMKSINTIVG DKNMDWEKRV DALKKIRSLL MINVQNSPTF TQQLKDLSIA
FLDILKELRS QVIREACITL AYMSKLLKNR LDQFVIYILQ ELINLIQNSA KVISSAGIIA
LKYVIKHTHA PKIVPIITQN LMQSKSKDIR STLCEIMILL FDEWPTKTLE KNSSLLRDAL
RKGISDADSE ARRHSRCAFW SFRRHFPDLA DNLYSSLDPA TQRMMERDRD NLGTNGTNSM
SVSLRGSNSS LNSVPGGVIK RRQSSGLRSP ASTQPPGNAT SVSTENLSCG QSSSSKLLRT
PSLPRTYSRN RSGIPVAHRD NTVPARAGLR SVSAVDTAAA QRARARAQYS NMARMKISSG
SASLQGQYAQ QARAKKIPLS NTPQQPPTPD RKIRSRSGVS QSQPTSRSTS PSSKLRDNFG
IASIYKQTGT IPKKHSGIPR SLVNSRETSP TRGTQFGSLR RNAYGTNSPR RLDRPPVNPA
RPVLAQKILQ QSREAESALA DALSPDDHDL STDFSRLGLH RKISRDESDE SEASSVCSER
SFDSYRRGND SFSWNGSRTR LDSSRTMIED IDTIIQLCAS THWSERKDGL INLTQYLSEG
KMLTSQQLQC VLDLFRKMFM DPHIKVYALF LDTVNELILS HSNDLHDWLF ILLTRLFQKL
GGDLLGSMHG KIWKTLQLIY EYFPAELQMQ CVFRILIDAA QTPNTKTRQA TLKFLTTLAT
TYCTAAQFVT HSQTQQLVDR AILKIVQTSL DQKSLELKSQ ARSCIVALYN CNPSQMTMTL
ANLPKQYQDT AKAIIQHHMR RSTSGTDSPS SPLSSSSPKP LLSPQQGLYS LQGGCNSRSR
QISIDVADSM NSEEVYKNLR KTTAEIQNYS FEAKLDRDAN SKDSGISQMG EVQIQNNENY
ILGSNGLNGH VGIDKDDSCN GSKTQSATTT ESNTPENTVR LDSIDLNQKP TIHSQRQHQY
TLTDTGELIV EGGIKENDVI KAAIVLSHET SPETCVQVLE NLQTCIKHGN CELPIKNFKA
IMKMLLNLME SQNFAVLIVA LHTLGRIVRS AEMKSCWSNF LELILLKIID CYKISKEVSR
EIDIIVVKIA SVLPLDISVN ILNPVIATGD FPANLCALKI LKELAHKQGK DLTDNHLDSI
MPNIARLADD SQSMVRKAAV FCMVELYIVM GEEKVKPKFA LLNASKIRLL NVYIAKSMSS
NKGSSS


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