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Mitogen-activated protein kinase 8 interacting protein 1

 H0X773_OTOGA            Unreviewed;       713 AA.
H0X773;
22-FEB-2012, integrated into UniProtKB/TrEMBL.
22-FEB-2012, sequence version 1.
22-NOV-2017, entry version 33.
SubName: Full=Mitogen-activated protein kinase 8 interacting protein 1 {ECO:0000313|Ensembl:ENSOGAP00000011248};
Name=MAPK8IP1 {ECO:0000313|Ensembl:ENSOGAP00000011248};
Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini;
Lorisiformes; Galagidae; Otolemur.
NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000011248, ECO:0000313|Proteomes:UP000005225};
[1] {ECO:0000313|Ensembl:ENSOGAP00000011248}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
The Broad Institute Genome Sequencing Platform;
Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
Walker B.J., Sharpe T., Hall G.;
"Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSOGAP00000011248}
IDENTIFICATION.
Ensembl;
Submitted (JAN-2012) to UniProtKB.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSOGAP00000011248}.
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EMBL; AAQR03002742; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AAQR03002743; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; XP_003781308.1; XM_003781260.1.
STRING; 30611.ENSOGAP00000011248; -.
Ensembl; ENSOGAT00000012560; ENSOGAP00000011248; ENSOGAG00000012556.
GeneID; 100953493; -.
CTD; 9479; -.
eggNOG; KOG3775; Eukaryota.
eggNOG; ENOG410ZFRJ; LUCA.
GeneTree; ENSGT00390000003908; -.
InParanoid; H0X773; -.
OMA; KQCYSGY; -.
OrthoDB; EOG091G0T9G; -.
TreeFam; TF325073; -.
Proteomes; UP000005225; Unassembled WGS sequence.
GO; GO:0044297; C:cell body; IEA:Ensembl.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0030425; C:dendrite; IEA:Ensembl.
GO; GO:0044302; C:dentate gyrus mossy fiber; IEA:Ensembl.
GO; GO:0016020; C:membrane; IEA:Ensembl.
GO; GO:0045202; C:synapse; IEA:Ensembl.
GO; GO:0019894; F:kinesin binding; IEA:Ensembl.
GO; GO:0005078; F:MAP-kinase scaffold activity; IEA:Ensembl.
GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
GO; GO:0007258; P:JUN phosphorylation; IEA:Ensembl.
GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
GO; GO:0046328; P:regulation of JNK cascade; IEA:Ensembl.
GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
GO; GO:0016192; P:vesicle-mediated transport; IEA:Ensembl.
CDD; cd11943; SH3_JIP1; 1.
Gene3D; 2.30.29.30; -; 1.
InterPro; IPR035638; JIP1_SH3.
InterPro; IPR011993; PH-like_dom_sf.
InterPro; IPR006020; PTB/PI_dom.
InterPro; IPR036028; SH3-like_dom_sf.
InterPro; IPR001452; SH3_domain.
Pfam; PF00640; PID; 1.
Pfam; PF14604; SH3_9; 1.
SMART; SM00462; PTB; 1.
SMART; SM00326; SH3; 1.
SUPFAM; SSF50044; SSF50044; 2.
SUPFAM; SSF50729; SSF50729; 1.
PROSITE; PS01179; PID; 1.
PROSITE; PS50002; SH3; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000005225};
Reference proteome {ECO:0000313|Proteomes:UP000005225};
SH3 domain {ECO:0000256|PROSITE-ProRule:PRU00192}.
DOMAIN 490 551 SH3. {ECO:0000259|PROSITE:PS50002}.
DOMAIN 568 702 PID. {ECO:0000259|PROSITE:PS01179}.
SEQUENCE 713 AA; 77831 MW; 8E8AA5DA504D3FBD CRC64;
MAERESGGLG GGAASPPAAS PFLGLHIASP PNFRLTHDIS LEEFEDEDLS EITDECGISL
QCKDTLSLRP PRSGLLSAGG GGGGAGSRLQ AEMLQMDLID AAGDTPGAED DEEEDEEERA
ARRPGAGPPE AESGQDLAPR VQGQGQGQGL GLGSGDTYRP KRPTTLNLFP QVPRSQDTLN
NNSLGKKHSW QDRVSRSSSP LKTGEQTPPH EHICLSDELP PQSSPVPTKD RGTSTDSPCR
RSTATQMAPP SGAPAAQPSG RGNSHRDRIH YQADVRLEAT EEIYLTPVQR PPDPAEPTSA
FLPPTESRMS VSSDPDPAAY PATAGRPHPS ISEEDEGFDC LSSPERVEPQ GGGWQGSLGE
PPPPPRASLS SDTSALSYDS VKYTLVVDEH AQLELVSLRP CFGDYSDESD SATVYDNCAS
ASSPYESAIG EEYEEAPRPR PPACLSEDST PDEPDVHFSK KFLNVFMSGR SRSSSAESFG
LFSCVINGEE QEQTHRAIFR FVPRHEDELE LEVDDPLLVE LQAEDYWYEA YNMRTGARGV
FPAYYAIEVT KEPEHMAALA KNSDWVDQFR VKFLGSVQVP YHKGNDVLCA AMQKIATTRR
LTVHFNPPSS CILEISVRGV KIGVKADDSQ EAKGNKCSHF FQLKNISFCG YHPKNNKYFG
FITKHPADHR FACHVFVSED STKVLAESVG RAFQQFYKQF VEYTCPTEDI YLE


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