Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Multidrug resistance protein 1A (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (MDR1A) (Multidrug resistance protein 3) (P-glycoprotein 3)

 MDR1A_MOUSE             Reviewed;        1276 AA.
P21447; Q5I1Y5;
01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
16-JUN-2009, sequence version 3.
12-SEP-2018, entry version 166.
RecName: Full=Multidrug resistance protein 1A;
EC=3.6.3.44;
AltName: Full=ATP-binding cassette sub-family B member 1A;
AltName: Full=MDR1A;
AltName: Full=Multidrug resistance protein 3;
AltName: Full=P-glycoprotein 3;
Name=Abcb1a; Synonyms=Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
PubMed=1969610; DOI=10.1128/MCB.10.4.1652;
Devault A., Gros P.;
"Two members of the mouse mdr gene family confer multidrug resistance
with overlapping but distinct drug specificities.";
Mol. Cell. Biol. 10:1652-1663(1990).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
PubMed=1972547; DOI=10.1128/MCB.10.7.3596;
Hsu S.I.H., Cohen D., Kirschner L.S., Lothstein L., Hartstein M.,
Horwitz S.B.;
"Structural analysis of the mouse mdr1a (P-glycoprotein) promoter
reveals the basis for differential transcript heterogeneity in
multidrug-resistant J774.2 cells.";
Mol. Cell. Biol. 10:3596-3606(1990).
[3]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=BALB/cJ;
Pimprale S.S., Xiao G., Patten C., Crespi C.;
"Heterologus expression of mouse mdr1a (Abcb1a), (P-glycoprotein),
using the insect cell baculovirus expression system.";
Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
[5]
NUCLEOTIDE SEQUENCE [MRNA] OF 173-1276.
STRAIN=BALB/cJ;
PubMed=2473069;
Hsu S.I.H., Lothstein L., Horwitz S.B.;
"Differential overexpression of three mdr gene family members in
multidrug-resistant J774.2 mouse cells. Evidence that distinct P-
glycoprotein precursors are encoded by unique mdr genes.";
J. Biol. Chem. 264:12053-12062(1989).
[6]
PROTEIN SEQUENCE OF 273-282, AND IDENTIFICATION BY MASS SPECTROMETRY.
STRAIN=OF1; TISSUE=Hippocampus;
Lubec G., Sunyer B., Chen W.-Q.;
Submitted (JAN-2009) to UniProtKB.
[7]
IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
TISSUE=Heart, and Lung;
PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
"A tissue-specific atlas of mouse protein phosphorylation and
expression.";
Cell 143:1174-1189(2010).
[8]
X-RAY CRYSTALLOGRAPHY (3.8 ANGSTROMS) IN COMPLEXES WITH INHIBITORS,
FUNCTION, AND TOPOLOGY.
PubMed=19325113; DOI=10.1126/science.1168750;
Aller S.G., Yu J., Ward A., Weng Y., Chittaboina S., Zhuo R.,
Harrell P.M., Trinh Y.T., Zhang Q., Urbatsch I.L., Chang G.;
"Structure of P-glycoprotein reveals a molecular basis for poly-
specific drug binding.";
Science 323:1718-1722(2009).
-!- FUNCTION: Energy-dependent efflux pump responsible for decreased
drug accumulation in multidrug-resistant cells.
{ECO:0000269|PubMed:19325113}.
-!- CATALYTIC ACTIVITY: ATP + H(2)O + xenobiotic(In) = ADP + phosphate
+ xenobiotic(Out).
-!- SUBUNIT: Interacts with PSMB5. {ECO:0000250}.
-!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
-!- MISCELLANEOUS: In mouse the MDR gene family includes three or more
related but distinct cellular genes.
-!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCB
family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; M30697; AAA39517.1; -; mRNA.
EMBL; M33581; AAA39514.1; -; mRNA.
EMBL; M33580; AAA39518.1; -; Genomic_DNA.
EMBL; AY864315; AAW56448.1; -; mRNA.
EMBL; CH466600; EDL14677.1; -; Genomic_DNA.
EMBL; M24417; AAA03243.1; -; mRNA.
CCDS; CCDS19084.1; -.
PIR; A34175; DVMS1A.
PIR; A34786; A34786.
RefSeq; NP_035206.2; NM_011076.2.
RefSeq; XP_006503618.1; XM_006503555.3.
RefSeq; XP_006503619.1; XM_006503556.3.
UniGene; Mm.207354; -.
PDB; 3G5U; X-ray; 3.80 A; A/B=1-1276.
PDB; 3G60; X-ray; 4.40 A; A/B=1-1276.
PDB; 3G61; X-ray; 4.35 A; A/B=1-1276.
PDB; 4KSB; X-ray; 3.80 A; A=1-1276.
PDB; 4KSC; X-ray; 4.00 A; A=1-1276.
PDB; 4KSD; X-ray; 4.10 A; A=1-1276.
PDB; 4LSG; X-ray; 3.80 A; A/B=1-1276.
PDB; 4M1M; X-ray; 3.80 A; A/B=1-1276.
PDB; 4M2S; X-ray; 4.40 A; A/B=1-1276.
PDB; 4M2T; X-ray; 4.35 A; A/B=1-1276.
PDB; 4Q9H; X-ray; 3.40 A; A=1-1276.
PDB; 4Q9I; X-ray; 3.78 A; A=1-1276.
PDB; 4Q9J; X-ray; 3.60 A; A=1-1276.
PDB; 4Q9K; X-ray; 3.80 A; A=1-1276.
PDB; 4Q9L; X-ray; 3.80 A; A=1-1276.
PDB; 4XWK; X-ray; 3.50 A; A=1-1276.
PDB; 5KO2; X-ray; 3.30 A; A/B=1-1276.
PDB; 5KOY; X-ray; 3.85 A; A/B=1-1276.
PDB; 5KPD; X-ray; 3.35 A; A/B=1-1276.
PDB; 5KPI; X-ray; 4.01 A; A/B=1-1276.
PDB; 5KPJ; X-ray; 3.50 A; A=1-1276.
PDB; 6GDI; EM; 7.90 A; A=1-1276.
PDBsum; 3G5U; -.
PDBsum; 3G60; -.
PDBsum; 3G61; -.
PDBsum; 4KSB; -.
PDBsum; 4KSC; -.
PDBsum; 4KSD; -.
PDBsum; 4LSG; -.
PDBsum; 4M1M; -.
PDBsum; 4M2S; -.
PDBsum; 4M2T; -.
PDBsum; 4Q9H; -.
PDBsum; 4Q9I; -.
PDBsum; 4Q9J; -.
PDBsum; 4Q9K; -.
PDBsum; 4Q9L; -.
PDBsum; 4XWK; -.
PDBsum; 5KO2; -.
PDBsum; 5KOY; -.
PDBsum; 5KPD; -.
PDBsum; 5KPI; -.
PDBsum; 5KPJ; -.
PDBsum; 6GDI; -.
ProteinModelPortal; P21447; -.
SMR; P21447; -.
IntAct; P21447; 1.
MINT; P21447; -.
STRING; 10090.ENSMUSP00000041204; -.
BindingDB; P21447; -.
ChEMBL; CHEMBL2573; -.
iPTMnet; P21447; -.
PhosphoSitePlus; P21447; -.
MaxQB; P21447; -.
PaxDb; P21447; -.
PeptideAtlas; P21447; -.
PRIDE; P21447; -.
Ensembl; ENSMUST00000047753; ENSMUSP00000041204; ENSMUSG00000040584.
GeneID; 18671; -.
KEGG; mmu:18671; -.
UCSC; uc008wkl.1; mouse.
CTD; 18671; -.
MGI; MGI:97570; Abcb1a.
eggNOG; KOG0055; Eukaryota.
eggNOG; COG1132; LUCA.
GeneTree; ENSGT00530000062896; -.
HOVERGEN; HBG080809; -.
InParanoid; P21447; -.
KO; K05658; -.
OMA; MQTRGNE; -.
OrthoDB; EOG091G0HVA; -.
PhylomeDB; P21447; -.
TreeFam; TF105193; -.
Reactome; R-MMU-382556; ABC-family proteins mediated transport.
EvolutionaryTrace; P21447; -.
PRO; PR:P21447; -.
Proteomes; UP000000589; Chromosome 5.
Bgee; ENSMUSG00000040584; Expressed in 215 organ(s), highest expression level in brain blood vessel.
Genevisible; P21447; MM.
GO; GO:0045177; C:apical part of cell; ISO:MGI.
GO; GO:0016324; C:apical plasma membrane; IDA:BHF-UCL.
GO; GO:0031526; C:brush border membrane; ISO:MGI.
GO; GO:0009986; C:cell surface; ISO:MGI.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0046581; C:intercellular canaliculus; IDA:MGI.
GO; GO:0016020; C:membrane; ISO:MGI.
GO; GO:0005886; C:plasma membrane; TAS:Reactome.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO; GO:0042623; F:ATPase activity, coupled; IDA:MGI.
GO; GO:0099038; F:ceramide-translocating ATPase activity; IDA:BHF-UCL.
GO; GO:0090554; F:phosphatidylcholine-translocating ATPase activity; IDA:BHF-UCL.
GO; GO:0090555; F:phosphatidylethanolamine-translocating ATPase activity; IDA:BHF-UCL.
GO; GO:0008559; F:xenobiotic transmembrane transporting ATPase activity; EXP:Reactome.
GO; GO:0033231; P:carbohydrate export; ISO:MGI.
GO; GO:0099040; P:ceramide translocation; IDA:BHF-UCL.
GO; GO:0043215; P:daunorubicin transport; ISO:MGI.
GO; GO:0046618; P:drug export; ISO:MGI.
GO; GO:0006855; P:drug transmembrane transport; ISO:MGI.
GO; GO:0015893; P:drug transport; IDA:MGI.
GO; GO:1990962; P:drug transport across blood-brain barrier; ISO:MGI.
GO; GO:0060856; P:establishment of blood-brain barrier; ISO:MGI.
GO; GO:1990963; P:establishment of blood-retinal barrier; ISO:MGI.
GO; GO:0000086; P:G2/M transition of mitotic cell cycle; ISO:MGI.
GO; GO:0009914; P:hormone transport; ISO:MGI.
GO; GO:0050892; P:intestinal absorption; ISO:MGI.
GO; GO:0035633; P:maintenance of permeability of blood-brain barrier; ISO:MGI.
GO; GO:0060548; P:negative regulation of cell death; ISO:MGI.
GO; GO:0045332; P:phospholipid translocation; IDA:BHF-UCL.
GO; GO:1901529; P:positive regulation of anion channel activity; ISO:MGI.
GO; GO:2001025; P:positive regulation of response to drug; ISO:MGI.
GO; GO:2001225; P:regulation of chloride transport; ISO:MGI.
GO; GO:1904478; P:regulation of intestinal absorption; ISO:MGI.
GO; GO:0047484; P:regulation of response to osmotic stress; ISO:MGI.
GO; GO:0072089; P:stem cell proliferation; ISO:MGI.
InterPro; IPR003593; AAA+_ATPase.
InterPro; IPR011527; ABC1_TM_dom.
InterPro; IPR036640; ABC1_TM_sf.
InterPro; IPR003439; ABC_transporter-like.
InterPro; IPR017871; ABC_transporter_CS.
InterPro; IPR027417; P-loop_NTPase.
Pfam; PF00664; ABC_membrane; 2.
Pfam; PF00005; ABC_tran; 2.
SMART; SM00382; AAA; 2.
SUPFAM; SSF52540; SSF52540; 2.
SUPFAM; SSF90123; SSF90123; 2.
PROSITE; PS50929; ABC_TM1F; 2.
PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
1: Evidence at protein level;
3D-structure; ATP-binding; Cell membrane; Complete proteome;
Direct protein sequencing; Glycoprotein; Hydrolase; Membrane;
Nucleotide-binding; Phosphoprotein; Reference proteome; Repeat;
Transmembrane; Transmembrane helix; Transport.
CHAIN 1 1276 Multidrug resistance protein 1A.
/FTId=PRO_0000093336.
TOPO_DOM 1 43 Cytoplasmic. {ECO:0000250}.
TRANSMEM 44 66 Helical.
TOPO_DOM 67 112 Extracellular. {ECO:0000250}.
TRANSMEM 113 133 Helical.
TOPO_DOM 134 182 Cytoplasmic. {ECO:0000250}.
TRANSMEM 183 204 Helical.
TOPO_DOM 205 211 Extracellular. {ECO:0000250}.
TRANSMEM 212 232 Helical.
TOPO_DOM 233 290 Cytoplasmic. {ECO:0000250}.
TRANSMEM 291 312 Helical.
TOPO_DOM 313 326 Extracellular. {ECO:0000250}.
TRANSMEM 327 348 Helical.
TOPO_DOM 349 707 Cytoplasmic. {ECO:0000250}.
TRANSMEM 708 728 Helical.
TOPO_DOM 729 752 Extracellular. {ECO:0000250}.
TRANSMEM 753 773 Helical.
TOPO_DOM 774 828 Cytoplasmic. {ECO:0000250}.
TRANSMEM 829 849 Helical.
TOPO_DOM 850 850 Extracellular. {ECO:0000250}.
TRANSMEM 851 870 Helical.
TOPO_DOM 871 930 Cytoplasmic. {ECO:0000250}.
TRANSMEM 931 953 Helical.
TOPO_DOM 954 969 Extracellular. {ECO:0000250}.
TRANSMEM 970 991 Helical.
TOPO_DOM 992 1276 Cytoplasmic. {ECO:0000250}.
DOMAIN 50 353 ABC transmembrane type-1 1.
{ECO:0000255|PROSITE-ProRule:PRU00441}.
DOMAIN 388 624 ABC transporter 1. {ECO:0000255|PROSITE-
ProRule:PRU00434}.
DOMAIN 707 996 ABC transmembrane type-1 2.
{ECO:0000255|PROSITE-ProRule:PRU00441}.
DOMAIN 1031 1269 ABC transporter 2. {ECO:0000255|PROSITE-
ProRule:PRU00434}.
NP_BIND 423 430 ATP 1. {ECO:0000255|PROSITE-
ProRule:PRU00434}.
NP_BIND 1066 1073 ATP 2. {ECO:0000255|PROSITE-
ProRule:PRU00434}.
MOD_RES 656 656 Phosphoserine.
{ECO:0000250|UniProtKB:P06795}.
CARBOHYD 83 83 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 87 87 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 90 90 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CONFLICT 526 527 QL -> HV (in Ref. 2; AAA39514 and 5;
AAA03243). {ECO:0000305}.
CONFLICT 939 939 S -> F (in Ref. 1; AAA39517).
{ECO:0000305}.
CONFLICT 1036 1036 V -> F (in Ref. 1; AAA39517).
{ECO:0000305}.
HELIX 35 38 {ECO:0000244|PDB:5KO2}.
TURN 39 41 {ECO:0000244|PDB:5KO2}.
HELIX 44 82 {ECO:0000244|PDB:5KO2}.
HELIX 84 87 {ECO:0000244|PDB:5KO2}.
HELIX 96 153 {ECO:0000244|PDB:5KO2}.
HELIX 156 161 {ECO:0000244|PDB:5KO2}.
HELIX 164 170 {ECO:0000244|PDB:5KO2}.
TURN 171 173 {ECO:0000244|PDB:5KO2}.
HELIX 174 180 {ECO:0000244|PDB:5KO2}.
TURN 181 183 {ECO:0000244|PDB:5KO2}.
HELIX 184 206 {ECO:0000244|PDB:5KO2}.
HELIX 208 232 {ECO:0000244|PDB:5KO2}.
HELIX 234 255 {ECO:0000244|PDB:5KO2}.
HELIX 257 263 {ECO:0000244|PDB:5KO2}.
HELIX 268 275 {ECO:0000244|PDB:5KO2}.
HELIX 279 318 {ECO:0000244|PDB:5KO2}.
HELIX 324 366 {ECO:0000244|PDB:5KO2}.
STRAND 388 395 {ECO:0000244|PDB:5KO2}.
STRAND 398 400 {ECO:0000244|PDB:5KPD}.
STRAND 401 403 {ECO:0000244|PDB:5KO2}.
STRAND 405 413 {ECO:0000244|PDB:5KO2}.
STRAND 418 427 {ECO:0000244|PDB:5KO2}.
HELIX 430 436 {ECO:0000244|PDB:5KO2}.
STRAND 443 449 {ECO:0000244|PDB:5KO2}.
HELIX 454 456 {ECO:0000244|PDB:5KO2}.
HELIX 459 464 {ECO:0000244|PDB:5KO2}.
STRAND 465 469 {ECO:0000244|PDB:5KO2}.
STRAND 477 479 {ECO:0000244|PDB:5KO2}.
HELIX 480 485 {ECO:0000244|PDB:5KO2}.
HELIX 493 502 {ECO:0000244|PDB:5KO2}.
HELIX 506 510 {ECO:0000244|PDB:5KO2}.
TURN 513 516 {ECO:0000244|PDB:5KO2}.
STRAND 521 524 {ECO:0000244|PDB:5KO2}.
HELIX 529 543 {ECO:0000244|PDB:5KO2}.
STRAND 546 552 {ECO:0000244|PDB:5KO2}.
STRAND 555 557 {ECO:0000244|PDB:5KO2}.
HELIX 559 573 {ECO:0000244|PDB:5KO2}.
STRAND 576 581 {ECO:0000244|PDB:5KO2}.
HELIX 585 588 {ECO:0000244|PDB:5KO2}.
STRAND 592 598 {ECO:0000244|PDB:5KO2}.
STRAND 601 606 {ECO:0000244|PDB:5KO2}.
HELIX 608 614 {ECO:0000244|PDB:5KO2}.
HELIX 617 625 {ECO:0000244|PDB:5KO2}.
HELIX 693 698 {ECO:0000244|PDB:5KO2}.
HELIX 699 703 {ECO:0000244|PDB:5KO2}.
HELIX 704 737 {ECO:0000244|PDB:5KO2}.
TURN 741 743 {ECO:0000244|PDB:5KO2}.
HELIX 744 794 {ECO:0000244|PDB:5KO2}.
HELIX 797 800 {ECO:0000244|PDB:5KO2}.
STRAND 802 805 {ECO:0000244|PDB:5KO2}.
HELIX 807 815 {ECO:0000244|PDB:5KO2}.
TURN 816 819 {ECO:0000244|PDB:5KO2}.
HELIX 820 824 {ECO:0000244|PDB:5KO2}.
HELIX 826 849 {ECO:0000244|PDB:5KO2}.
HELIX 851 885 {ECO:0000244|PDB:5KO2}.
HELIX 887 898 {ECO:0000244|PDB:5KO2}.
HELIX 900 906 {ECO:0000244|PDB:5KO2}.
HELIX 909 961 {ECO:0000244|PDB:5KO2}.
STRAND 962 964 {ECO:0000244|PDB:4Q9H}.
HELIX 967 988 {ECO:0000244|PDB:5KO2}.
HELIX 994 1009 {ECO:0000244|PDB:5KO2}.
STRAND 1031 1038 {ECO:0000244|PDB:5KO2}.
STRAND 1049 1056 {ECO:0000244|PDB:5KO2}.
STRAND 1061 1067 {ECO:0000244|PDB:5KO2}.
HELIX 1072 1079 {ECO:0000244|PDB:5KO2}.
STRAND 1086 1092 {ECO:0000244|PDB:5KO2}.
HELIX 1097 1099 {ECO:0000244|PDB:5KO2}.
HELIX 1102 1107 {ECO:0000244|PDB:5KO2}.
STRAND 1109 1112 {ECO:0000244|PDB:5KO2}.
STRAND 1120 1122 {ECO:0000244|PDB:5KO2}.
HELIX 1123 1128 {ECO:0000244|PDB:5KO2}.
HELIX 1138 1147 {ECO:0000244|PDB:5KO2}.
HELIX 1151 1155 {ECO:0000244|PDB:5KO2}.
STRAND 1157 1159 {ECO:0000244|PDB:5KO2}.
TURN 1160 1162 {ECO:0000244|PDB:5KO2}.
STRAND 1164 1170 {ECO:0000244|PDB:5KO2}.
HELIX 1174 1188 {ECO:0000244|PDB:5KO2}.
STRAND 1191 1197 {ECO:0000244|PDB:5KO2}.
HELIX 1204 1217 {ECO:0000244|PDB:5KO2}.
TURN 1218 1220 {ECO:0000244|PDB:5KO2}.
STRAND 1221 1226 {ECO:0000244|PDB:5KO2}.
HELIX 1230 1233 {ECO:0000244|PDB:5KO2}.
STRAND 1237 1243 {ECO:0000244|PDB:5KO2}.
STRAND 1246 1251 {ECO:0000244|PDB:5KO2}.
HELIX 1253 1259 {ECO:0000244|PDB:5KO2}.
HELIX 1262 1269 {ECO:0000244|PDB:5KO2}.
SEQUENCE 1276 AA; 140647 MW; 542E101DF18DDC52 CRC64;
MELEEDLKGR ADKNFSKMGK KSKKEKKEKK PAVSVLTMFR YAGWLDRLYM LVGTLAAIIH
GVALPLMMLI FGDMTDSFAS VGNVSKNSTN MSEADKRAMF AKLEEEMTTY AYYYTGIGAG
VLIVAYIQVS FWCLAAGRQI HKIRQKFFHA IMNQEIGWFD VHDVGELNTR LTDDVSKINE
GIGDKIGMFF QAMATFFGGF IIGFTRGWKL TLVILAISPV LGLSAGIWAK ILSSFTDKEL
HAYAKAGAVA EEVLAAIRTV IAFGGQKKEL ERYNNNLEEA KRLGIKKAIT ANISMGAAFL
LIYASYALAF WYGTSLVISK EYSIGQVLTV FFSVLIGAFS VGQASPNIEA FANARGAAYE
VFKIIDNKPS IDSFSKSGHK PDNIQGNLEF KNIHFSYPSR KEVQILKGLN LKVKSGQTVA
LVGNSGCGKS TTVQLMQRLY DPLDGMVSID GQDIRTINVR YLREIIGVVS QEPVLFATTI
AENIRYGRED VTMDEIEKAV KEANAYDFIM KLPHQFDTLV GERGAQLSGG QKQRIAIARA
LVRNPKILLL DEATSALDTE SEAVVQAALD KAREGRTTIV IAHRLSTVRN ADVIAGFDGG
VIVEQGNHDE LMREKGIYFK LVMTQTAGNE IELGNEACKS KDEIDNLDMS SKDSGSSLIR
RRSTRKSICG PHDQDRKLST KEALDEDVPP ASFWRILKLN STEWPYFVVG IFCAIINGGL
QPAFSVIFSK VVGVFTNGGP PETQRQNSNL FSLLFLILGI ISFITFFLQG FTFGKAGEIL
TKRLRYMVFK SMLRQDVSWF DDPKNTTGAL TTRLANDAAQ VKGATGSRLA VIFQNIANLG
TGIIISLIYG WQLTLLLLAI VPIIAIAGVV EMKMLSGQAL KDKKELEGSG KIATEAIENF
RTVVSLTREQ KFETMYAQSL QIPYRNAMKK AHVFGITFSF TQAMMYFSYA ACFRFGAYLV
TQQLMTFENV LLVFSAIVFG AMAVGQVSSF APDYAKATVS ASHIIRIIEK TPEIDSYSTQ
GLKPNMLEGN VQFSGVVFNY PTRPSIPVLQ GLSLEVKKGQ TLALVGSSGC GKSTVVQLLE
RFYDPMAGSV FLDGKEIKQL NVQWLRAQLG IVSQEPILFD CSIAENIAYG DNSRVVSYEE
IVRAAKEANI HQFIDSLPDK YNTRVGDKGT QLSGGQKQRI AIARALVRQP HILLLDEATS
ALDTESEKVV QEALDKAREG RTCIVIAHRL STIQNADLIV VIQNGKVKEH GTHQQLLAQK
GIYFSMVSVQ AGAKRS


Related products :

Catalog number Product name Quantity
EIAAB25426 Abcc2,ATP-binding cassette sub-family C member 2,Canalicular multidrug resistance protein,Canalicular multispecific organic anion transporter 1,Cmoat,Cmrp,Mrp2,Multidrug resistance-associated protein
EIAAB25437 ABCC6,Anthracycline resistance-associated protein,ARA,ATP-binding cassette sub-family C member 6,Homo sapiens,Human,MOAT-E,MRP6,Multidrug resistance-associated protein 6,Multi-specific organic anion t
EIAAB25429 ABCC2,ATP-binding cassette sub-family C member 2,Canalicular multidrug resistance protein,Canalicular multispecific organic anion transporter 1,CMOAT,CMOAT1,CMRP,Homo sapiens,Human,MRP2,Multidrug resi
EIAAB25439 Abcc6,ATP-binding cassette sub-family C member 6,Mouse,Mrp6,Multidrug resistance-associated protein 6,Mus musculus
EIAAB25440 Abcc10,ATP-binding cassette sub-family C member 10,Mouse,Mrp7,Multidrug resistance-associated protein 7,Mus musculus
EIAAB25442 Abcc12,ATP-binding cassette sub-family C member 12,Mrp9,Multidrug resistance-associated protein 9,Rat,Rattus norvegicus
EIAAB25444 Abcc12,ATP-binding cassette sub-family C member 12,Mouse,Mrp9,Multidrug resistance-associated protein 9,Mus musculus
EIAAB25438 Abcc6,ATP-binding cassette sub-family C member 6,Mlp1,MLP-1,Mrp6,MRP-like protein 1,Multidrug resistance-associated protein 6,Rat,Rattus norvegicus
EIAAB25443 ABCC12,ATP-binding cassette sub-family C member 12,Homo sapiens,Human,MRP9,Multidrug resistance-associated protein 9
U0960p CLIA ABCG2,ATP-binding cassette sub-family G member 2,BMDP,Brain multidrug resistance protein,Pig,Sus scrofa 96T
EIAAB25436 Abcc5,Abcc5a,ATP-binding cassette sub-family C member 5,Mrp5,Multidrug resistance-associated protein 5,Rat,Rattus norvegicus
E0960p ELISA ABCG2,ATP-binding cassette sub-family G member 2,BMDP,Brain multidrug resistance protein,Pig,Sus scrofa 96T
E0960p ELISA kit ABCG2,ATP-binding cassette sub-family G member 2,BMDP,Brain multidrug resistance protein,Pig,Sus scrofa 96T
EIAAB25441 ABCC10,ATP-binding cassette sub-family C member 10,Homo sapiens,Human,MRP7,Multidrug resistance-associated protein 7,SIMRP7
EIAAB25432 Abcc3,ATP-binding cassette sub-family C member 3,Canalicular multispecific organic anion transporter 2,Cmoat2,Mlp2,MLP-2,Mrp3,MRP-like protein 2,Multidrug resistance-associated protein 3,Rat,Rattus no
EIAAB25431 Abcc3,ATP-binding cassette sub-family C member 3,Canalicular multispecific organic anion transporter 2,Cmoat2,Mouse,Mrp3,Multidrug resistance-associated protein 3,Mus musculus
EIAAB25434 Abcc5,Abcc5a,ATP-binding cassette sub-family C member 5,MOAT-C,Mouse,Mrp5,Multidrug resistance-associated protein 5,Multi-specific organic anion transporter C,Mus musculus,SMRP
E1068b ELISA ABCC1,ATP-binding cassette sub-family C member 1,Bos taurus,Bovine,Leukotriene C(4) transporter,LTC4 transporter,MRP1,Multidrug resistance-associated protein 1 96T
U1068r CLIA Abcc1,ATP-binding cassette sub-family C member 1,Leukotriene C(4) transporter,LTC4 transporter,Mrp1,Multidrug resistance-associated protein 1,Rat,Rattus norvegicus 96T
E1068b ELISA kit ABCC1,ATP-binding cassette sub-family C member 1,Bos taurus,Bovine,Leukotriene C(4) transporter,LTC4 transporter,MRP1,Multidrug resistance-associated protein 1 96T
U1068b CLIA ABCC1,ATP-binding cassette sub-family C member 1,Bos taurus,Bovine,Leukotriene C(4) transporter,LTC4 transporter,MRP1,Multidrug resistance-associated protein 1 96T
E1068r ELISA kit Abcc1,ATP-binding cassette sub-family C member 1,Leukotriene C(4) transporter,LTC4 transporter,Mrp1,Multidrug resistance-associated protein 1,Rat,Rattus norvegicus 96T
E1068r ELISA Abcc1,ATP-binding cassette sub-family C member 1,Leukotriene C(4) transporter,LTC4 transporter,Mrp1,Multidrug resistance-associated protein 1,Rat,Rattus norvegicus 96T
EIAAB25435 ABCC5,ATP-binding cassette sub-family C member 5,Homo sapiens,Human,MOAT-C,MRP5,Multidrug resistance-associated protein 5,Multi-specific organic anion transporter C,pABC11,SMRP
U1068h CLIA ABCC1,ATP-binding cassette sub-family C member 1,Homo sapiens,Human,Leukotriene C(4) transporter,LTC4 transporter,MRP,MRP1,Multidrug resistance-associated protein 1 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur