Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

MyoD family inhibitor (Myogenic repressor I-mf)

 MDFI_HUMAN              Reviewed;         246 AA.
15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
01-MAY-1997, sequence version 1.
18-JUL-2018, entry version 145.
RecName: Full=MyoD family inhibitor;
AltName: Full=Myogenic repressor I-mf;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
TISSUE=Fetal brain;
PubMed=9250874; DOI=10.1007/s003359900517;
Kraut N.;
"The gene encoding I-mf (Mdfi) maps to human chromosome 6p21 and mouse
chromosome 17.";
Mamm. Genome 8:618-619(1997).
PubMed=14574404; DOI=10.1038/nature02055;
Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
"The DNA sequence and analysis of human chromosome 6.";
Nature 425:805-811(2003).
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
PubMed=17289077; DOI=10.1016/j.jmb.2007.01.020;
Wang Q., Young T.M., Mathews M.B., Pe'ery T.;
"Developmental regulators containing the I-mfa domain interact with T
cyclins and Tat and modulate transcription.";
J. Mol. Biol. 367:630-646(2007).
-!- FUNCTION: Inhibits the transactivation activity of the Myod family
of myogenic factors and represses myogenesis. Acts by associating
with Myod family members and retaining them in the cytoplasm by
masking their nuclear localization signals. Can also interfere
with the DNA-binding activity of Myod family members. Plays an
important role in trophoblast and chondrogenic differentiation.
Regulates the transcriptional activity of TCF7L1/TCF3 by
interacting directly with TCF7L1/TCF3 and preventing it from
binding DNA. Binds to the axin complex, resulting in an increase
in the level of free beta-catenin. Affects axin regulation of the
WNT and JNK signaling pathways (By similarity). {ECO:0000250}.
-!- SUBUNIT: The C-terminus interacts with AXIN1 and LEF1 (By
similarity). Interacts with CCNT2 (PubMed:17289077).
{ECO:0000250|UniProtKB:P70331, ECO:0000269|PubMed:17289077}.
Self; NbExp=4; IntAct=EBI-724076, EBI-724076;
Q5BKY6:-; NbExp=3; IntAct=EBI-724076, EBI-10243533;
Q5W150:-; NbExp=5; IntAct=EBI-724076, EBI-10248148;
Q5XG85:-; NbExp=5; IntAct=EBI-724076, EBI-10248413;
Q16613:AANAT; NbExp=6; IntAct=EBI-724076, EBI-7451846;
A0A0S2Z645:ABCF3; NbExp=3; IntAct=EBI-724076, EBI-16432404;
P82987:ADAMTSL3; NbExp=5; IntAct=EBI-724076, EBI-10221726;
Q02040-3:AKAP17A; NbExp=3; IntAct=EBI-724076, EBI-10222656;
P29972:AQP1; NbExp=6; IntAct=EBI-724076, EBI-745213;
P55064:AQP5; NbExp=3; IntAct=EBI-724076, EBI-746103;
A7KAX9:ARHGAP32; NbExp=3; IntAct=EBI-724076, EBI-308663;
Q03989:ARID5A; NbExp=4; IntAct=EBI-724076, EBI-948603;
Q5T686:AVPI1; NbExp=6; IntAct=EBI-724076, EBI-8640233;
A0A0S2Z4M1:AXIN1; NbExp=3; IntAct=EBI-724076, EBI-16429430;
O15169:AXIN1; NbExp=3; IntAct=EBI-724076, EBI-710484;
Q8TBE0:BAHD1; NbExp=6; IntAct=EBI-724076, EBI-742750;
A0A0S2Z5G4:BANP; NbExp=3; IntAct=EBI-724076, EBI-16429704;
B4DE54:BANP; NbExp=3; IntAct=EBI-724076, EBI-16429313;
Q8N9N5-2:BANP; NbExp=5; IntAct=EBI-724076, EBI-11524452;
Q8N9N5-7:BANP; NbExp=3; IntAct=EBI-724076, EBI-16429296;
Q9BXC9:BBS2; NbExp=5; IntAct=EBI-724076, EBI-748297;
Q9HBH7:BEX1; NbExp=5; IntAct=EBI-724076, EBI-7162175;
Q5T681:C10orf62; NbExp=7; IntAct=EBI-724076, EBI-744052;
Q6P5X5:C22orf39; NbExp=3; IntAct=EBI-724076, EBI-7317823;
Q9H7E9:C8orf33; NbExp=4; IntAct=EBI-724076, EBI-715389;
Q96LL4:C8orf48; NbExp=5; IntAct=EBI-724076, EBI-751596;
Q8NEC5:CATSPER1; NbExp=3; IntAct=EBI-724076, EBI-744545;
O43439:CBFA2T2; NbExp=4; IntAct=EBI-724076, EBI-748628;
Q14781:CBX2; NbExp=3; IntAct=EBI-724076, EBI-745934;
Q5T0F9:CC2D1B; NbExp=3; IntAct=EBI-724076, EBI-10245204;
Q8IYX3:CCDC116; NbExp=4; IntAct=EBI-724076, EBI-744311;
Q8N715:CCDC185; NbExp=3; IntAct=EBI-724076, EBI-740814;
Q9NVL8:CCDC198; NbExp=3; IntAct=EBI-724076, EBI-10238351;
Q96GN5:CDCA7L; NbExp=5; IntAct=EBI-724076, EBI-5278764;
Q8IVW4:CDKL3; NbExp=3; IntAct=EBI-724076, EBI-3919850;
Q8IYX8:CEP57L1; NbExp=5; IntAct=EBI-724076, EBI-1104570;
P07510-2:CHRNG; NbExp=5; IntAct=EBI-724076, EBI-11979451;
Q8NE01:CNNM3; NbExp=5; IntAct=EBI-724076, EBI-741032;
Q02930-3:CREB5; NbExp=7; IntAct=EBI-724076, EBI-10192698;
Q6DCB0:DAAM2; NbExp=3; IntAct=EBI-724076, EBI-10249414;
Q5TAQ9:DCAF8; NbExp=6; IntAct=EBI-724076, EBI-740686;
Q8TF63:DCANP1; NbExp=5; IntAct=EBI-724076, EBI-10275670;
Q96LJ7:DHRS1; NbExp=3; IntAct=EBI-724076, EBI-746300;
O94907:DKK1; NbExp=3; IntAct=EBI-724076, EBI-742864;
Q9NQL9:DMRT3; NbExp=5; IntAct=EBI-724076, EBI-9679045;
Q92608:DOCK2; NbExp=5; IntAct=EBI-724076, EBI-448771;
Q14240-2:EIF4A2; NbExp=3; IntAct=EBI-724076, EBI-10232522;
Q14241:ELOA; NbExp=5; IntAct=EBI-724076, EBI-742350;
Q9H0I2:ENKD1; NbExp=7; IntAct=EBI-724076, EBI-744099;
Q92731-3:ESR2; NbExp=3; IntAct=EBI-724076, EBI-12259414;
Q0VG06-3:FAAP100; NbExp=3; IntAct=EBI-724076, EBI-10226932;
Q9H5Z6:FAM124B; NbExp=4; IntAct=EBI-724076, EBI-741626;
Q3B820:FAM161A; NbExp=5; IntAct=EBI-724076, EBI-719941;
Q08E93:FAM27E3; NbExp=5; IntAct=EBI-724076, EBI-2602739;
Q96D16:FBXL18; NbExp=5; IntAct=EBI-724076, EBI-744419;
Q9NWN3:FBXO34; NbExp=3; IntAct=EBI-724076, EBI-719816;
Q9BVV2:FNDC11; NbExp=3; IntAct=EBI-724076, EBI-744935;
Q3SYB3:FOXD4L6; NbExp=5; IntAct=EBI-724076, EBI-6425864;
P15976-2:GATA1; NbExp=5; IntAct=EBI-724076, EBI-9090198;
P23769:GATA2; NbExp=3; IntAct=EBI-724076, EBI-2806671;
Q99988:GDF15; NbExp=4; IntAct=EBI-724076, EBI-2116863;
P04899:GNAI2; NbExp=5; IntAct=EBI-724076, EBI-353997;
P63218:GNG5; NbExp=3; IntAct=EBI-724076, EBI-10220734;
Q9NWQ4:GPATCH2L; NbExp=3; IntAct=EBI-724076, EBI-5666657;
Q9Y5Q8:GTF3C5; NbExp=3; IntAct=EBI-724076, EBI-1045409;
B4DNA4:hCG_20425; NbExp=5; IntAct=EBI-724076, EBI-7399002;
Q9NQ87:HEYL; NbExp=6; IntAct=EBI-724076, EBI-751092;
Q8WVV9:HNRNPLL; NbExp=4; IntAct=EBI-724076, EBI-535849;
P49639:HOXA1; NbExp=3; IntAct=EBI-724076, EBI-740785;
P09022:Hoxa1 (xeno); NbExp=3; IntAct=EBI-724076, EBI-3957603;
P17482:HOXB9; NbExp=5; IntAct=EBI-724076, EBI-745290;
Q12329:HSP42 (xeno); NbExp=3; IntAct=EBI-724076, EBI-8571;
P28222:HTR1B; NbExp=6; IntAct=EBI-724076, EBI-1056863;
Q92993:KAT5; NbExp=3; IntAct=EBI-724076, EBI-399080;
Q15053:KIAA0040; NbExp=5; IntAct=EBI-724076, EBI-2805673;
P52292:KPNA2; NbExp=3; IntAct=EBI-724076, EBI-349938;
A0A0S2Z3Z3:LAMB3; NbExp=3; IntAct=EBI-724076, EBI-16435132;
Q14847:LASP1; NbExp=3; IntAct=EBI-724076, EBI-742828;
Q5T7P3:LCE1B; NbExp=3; IntAct=EBI-724076, EBI-10245913;
Q5T5B0:LCE3E; NbExp=5; IntAct=EBI-724076, EBI-10245456;
Q5TA78:LCE4A; NbExp=5; IntAct=EBI-724076, EBI-10246358;
Q7Z4I7-5:LIMS2; NbExp=3; IntAct=EBI-724076, EBI-10257651;
O75427:LRCH4; NbExp=3; IntAct=EBI-724076, EBI-718707;
Q9Y5V3:MAGED1; NbExp=5; IntAct=EBI-724076, EBI-716006;
Q9HAY2:MAGEF1; NbExp=3; IntAct=EBI-724076, EBI-5525855;
O60336:MAPKBP1; NbExp=5; IntAct=EBI-724076, EBI-947402;
Q9H7H0:METTL17; NbExp=4; IntAct=EBI-724076, EBI-749353;
Q9H7H0-2:METTL17; NbExp=5; IntAct=EBI-724076, EBI-11098807;
Q92692:NECTIN2; NbExp=4; IntAct=EBI-724076, EBI-718419;
Q8WWR8:NEU4; NbExp=4; IntAct=EBI-724076, EBI-746964;
Q9NQX5:NPDC1; NbExp=7; IntAct=EBI-724076, EBI-748927;
F1D8P7:NR1H2; NbExp=5; IntAct=EBI-724076, EBI-10177172;
P55055:NR1H2; NbExp=3; IntAct=EBI-724076, EBI-745354;
Q13133:NR1H3; NbExp=3; IntAct=EBI-724076, EBI-781356;
Q13133-2:NR1H3; NbExp=3; IntAct=EBI-724076, EBI-12699353;
Q17RF5:ODAPH; NbExp=5; IntAct=EBI-724076, EBI-10239029;
Q7RTU3:OLIG3; NbExp=5; IntAct=EBI-724076, EBI-10225049;
P32242:OTX1; NbExp=7; IntAct=EBI-724076, EBI-740446;
Q14554:PDIA5; NbExp=3; IntAct=EBI-724076, EBI-953879;
Q8WV24:PHLDA1; NbExp=3; IntAct=EBI-724076, EBI-738731;
Q7Z2X4:PID1; NbExp=3; IntAct=EBI-724076, EBI-10256685;
Q9HB75:PIDD1; NbExp=3; IntAct=EBI-724076, EBI-520427;
Q8WWB5:PIH1D2; NbExp=5; IntAct=EBI-724076, EBI-10232538;
Q13526:PIN1; NbExp=6; IntAct=EBI-724076, EBI-714158;
P78337:PITX1; NbExp=3; IntAct=EBI-724076, EBI-748265;
Q58EX7:PLEKHG4; NbExp=3; IntAct=EBI-724076, EBI-949255;
O43741:PRKAB2; NbExp=7; IntAct=EBI-724076, EBI-1053424;
Q8WWY3:PRPF31; NbExp=5; IntAct=EBI-724076, EBI-1567797;
Q8WUK0:PTPMT1; NbExp=6; IntAct=EBI-724076, EBI-7199479;
Q3YEC7:RABL6; NbExp=2; IntAct=EBI-724076, EBI-742029;
Q06141:REG3A; NbExp=3; IntAct=EBI-724076, EBI-10223932;
Q96EN9:REX1BD; NbExp=5; IntAct=EBI-724076, EBI-745810;
Q0D2K3:RIPPLY1; NbExp=5; IntAct=EBI-724076, EBI-10226430;
A0A0S2Z4G9:RNF6; NbExp=3; IntAct=EBI-724076, EBI-16428950;
Q14D33:RTP5; NbExp=5; IntAct=EBI-724076, EBI-10217913;
Q9NUL5:RYDEN; NbExp=3; IntAct=EBI-724076, EBI-10313866;
P34164:SIP2 (xeno); NbExp=3; IntAct=EBI-724076, EBI-17187;
Q15475:SIX1; NbExp=2; IntAct=EBI-724076, EBI-743675;
Q9UBX3:SLC25A10; NbExp=7; IntAct=EBI-724076, EBI-750394;
Q9UBX3-2:SLC25A10; NbExp=3; IntAct=EBI-724076, EBI-12056597;
P06782:SNF1 (xeno); NbExp=3; IntAct=EBI-724076, EBI-17516;
Q6RVD6:SPATA8; NbExp=5; IntAct=EBI-724076, EBI-8635958;
Q9UQ90:SPG7; NbExp=6; IntAct=EBI-724076, EBI-717201;
O43609:SPRY1; NbExp=5; IntAct=EBI-724076, EBI-3866665;
O43597:SPRY2; NbExp=3; IntAct=EBI-724076, EBI-742487;
P35184:SQT1 (xeno); NbExp=3; IntAct=EBI-724076, EBI-17971;
P32589:SSE1 (xeno); NbExp=3; IntAct=EBI-724076, EBI-8648;
A0A0S2Z4E5:TEAD4; NbExp=3; IntAct=EBI-724076, EBI-16432288;
A0A0S2Z4F2:TEAD4; NbExp=3; IntAct=EBI-724076, EBI-16429215;
Q15583:TGIF1; NbExp=4; IntAct=EBI-724076, EBI-714215;
Q9P2T0:THEG; NbExp=3; IntAct=EBI-724076, EBI-751020;
P19237:TNNI1; NbExp=3; IntAct=EBI-724076, EBI-746692;
Q4VB56:TNP2; NbExp=3; IntAct=EBI-724076, EBI-10241829;
Q96RU7:TRIB3; NbExp=3; IntAct=EBI-724076, EBI-492476;
Q5W5X9:TTC23; NbExp=3; IntAct=EBI-724076, EBI-6447954;
Q6ZVT0:TTLL10; NbExp=3; IntAct=EBI-724076, EBI-7844656;
O75896:TUSC2; NbExp=5; IntAct=EBI-724076, EBI-1052725;
Q8TAI1:TYMSOS; NbExp=6; IntAct=EBI-724076, EBI-742060;
Q06418:TYRO3; NbExp=3; IntAct=EBI-724076, EBI-3951628;
Q9Y2K6:USP20; NbExp=3; IntAct=EBI-724076, EBI-2511991;
P40337:VHL; NbExp=3; IntAct=EBI-724076, EBI-301246;
P40337-2:VHL; NbExp=3; IntAct=EBI-724076, EBI-12157263;
Q15906:VPS72; NbExp=4; IntAct=EBI-724076, EBI-399189;
O96014:WNT11; NbExp=5; IntAct=EBI-724076, EBI-8058160;
P42947:YJL107C (xeno); NbExp=3; IntAct=EBI-724076, EBI-26023;
Q12259:YLR108C (xeno); NbExp=3; IntAct=EBI-724076, EBI-30776;
O43167:ZBTB24; NbExp=8; IntAct=EBI-724076, EBI-744471;
P24278:ZBTB25; NbExp=2; IntAct=EBI-724076, EBI-739899;
Q96C00:ZBTB9; NbExp=5; IntAct=EBI-724076, EBI-395708;
Q9Y260:ZFAB; NbExp=4; IntAct=EBI-724076, EBI-750052;
Q68DK2-5:ZFYVE26; NbExp=5; IntAct=EBI-724076, EBI-8656416;
Q8IZC7:ZNF101; NbExp=5; IntAct=EBI-724076, EBI-5278328;
Q15973:ZNF124; NbExp=5; IntAct=EBI-724076, EBI-2555767;
P52737:ZNF136; NbExp=9; IntAct=EBI-724076, EBI-749129;
P52744-2:ZNF138; NbExp=3; IntAct=EBI-724076, EBI-10213071;
Q12901-2:ZNF155; NbExp=3; IntAct=EBI-724076, EBI-10227379;
Q9UK11:ZNF223; NbExp=5; IntAct=EBI-724076, EBI-10322867;
Q9UIE0:ZNF230; NbExp=3; IntAct=EBI-724076, EBI-1105361;
Q14C61:ZNF264; NbExp=3; IntAct=EBI-724076, EBI-2826570;
Q14584:ZNF266; NbExp=5; IntAct=EBI-724076, EBI-7115319;
Q9H9D4:ZNF408; NbExp=5; IntAct=EBI-724076, EBI-347633;
Q8TAU3:ZNF417; NbExp=6; IntAct=EBI-724076, EBI-740727;
Q8N7K0:ZNF433; NbExp=3; IntAct=EBI-724076, EBI-10267553;
Q8NDP4:ZNF439; NbExp=7; IntAct=EBI-724076, EBI-747580;
Q8IYI8:ZNF440; NbExp=9; IntAct=EBI-724076, EBI-726439;
Q9ULM2:ZNF490; NbExp=6; IntAct=EBI-724076, EBI-1105370;
Q9BR84:ZNF559; NbExp=6; IntAct=EBI-724076, EBI-746605;
Q8TBZ8:ZNF564; NbExp=5; IntAct=EBI-724076, EBI-10273713;
Q3MI94:ZNF578; NbExp=3; IntAct=EBI-724076, EBI-10241108;
Q9P0T4:ZNF581; NbExp=6; IntAct=EBI-724076, EBI-745520;
Q96SQ5:ZNF587; NbExp=5; IntAct=EBI-724076, EBI-6427977;
Q96SK3:ZNF607; NbExp=4; IntAct=EBI-724076, EBI-747175;
O15015:ZNF646; NbExp=3; IntAct=EBI-724076, EBI-745608;
Q9BS34:ZNF670; NbExp=4; IntAct=EBI-724076, EBI-745276;
Q8IYX0:ZNF679; NbExp=3; IntAct=EBI-724076, EBI-745567;
A0A0S2Z5X4:ZNF688; NbExp=3; IntAct=EBI-724076, EBI-16429014;
Q96C28:ZNF707; NbExp=4; IntAct=EBI-724076, EBI-748111;
Q96H86:ZNF764; NbExp=3; IntAct=EBI-724076, EBI-745775;
Q15937:ZNF79; NbExp=3; IntAct=EBI-724076, EBI-10237274;
Q08AG5:ZNF844; NbExp=5; IntAct=EBI-724076, EBI-10225757;
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm
-!- SIMILARITY: Belongs to the MDFI family. {ECO:0000305}.
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
EMBL; U78313; AAB39748.1; -; mRNA.
EMBL; AL035588; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; BC007836; AAH07836.1; -; mRNA.
CCDS; CCDS4857.1; -.
RefSeq; NP_001287733.1; NM_001300804.1.
RefSeq; NP_001287734.1; NM_001300805.1.
RefSeq; NP_001287735.1; NM_001300806.1.
RefSeq; NP_005577.1; NM_005586.3.
UniGene; Hs.520119; -.
ProteinModelPortal; Q99750; -.
SMR; Q99750; -.
BioGrid; 110353; 238.
IntAct; Q99750; 417.
MINT; Q99750; -.
STRING; 9606.ENSP00000230321; -.
iPTMnet; Q99750; -.
PhosphoSitePlus; Q99750; -.
BioMuta; MDFI; -.
DMDM; 25090674; -.
MaxQB; Q99750; -.
PaxDb; Q99750; -.
PeptideAtlas; Q99750; -.
PRIDE; Q99750; -.
ProteomicsDB; 78457; -.
DNASU; 4188; -.
Ensembl; ENST00000230321; ENSP00000230321; ENSG00000112559.
Ensembl; ENST00000373051; ENSP00000362142; ENSG00000112559.
GeneID; 4188; -.
KEGG; hsa:4188; -.
UCSC; uc003oqq.5; human.
CTD; 4188; -.
EuPathDB; HostDB:ENSG00000112559.13; -.
GeneCards; MDFI; -.
HPA; HPA049973; -.
MIM; 604971; gene.
neXtProt; NX_Q99750; -.
OpenTargets; ENSG00000112559; -.
PharmGKB; PA30713; -.
eggNOG; ENOG410IYH9; Eukaryota.
eggNOG; ENOG410YK34; LUCA.
GeneTree; ENSGT00390000010600; -.
HOGENOM; HOG000001577; -.
HOVERGEN; HBG031704; -.
InParanoid; Q99750; -.
OrthoDB; EOG091G0RJH; -.
PhylomeDB; Q99750; -.
TreeFam; TF332113; -.
SIGNOR; Q99750; -.
ChiTaRS; MDFI; human.
GeneWiki; MDFI; -.
GenomeRNAi; 4188; -.
PRO; PR:Q99750; -.
Proteomes; UP000005640; Chromosome 6.
Bgee; ENSG00000112559; -.
CleanEx; HS_MDFI; -.
ExpressionAtlas; Q99750; baseline and differential.
Genevisible; Q99750; HS.
GO; GO:0005737; C:cytoplasm; TAS:ProtInc.
GO; GO:0005634; C:nucleus; ISS:UniProtKB.
GO; GO:0042802; F:identical protein binding; IPI:IntAct.
GO; GO:0008134; F:transcription factor binding; IBA:GO_Central.
GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; TAS:ProtInc.
GO; GO:0009950; P:dorsal/ventral axis specification; ISS:UniProtKB.
GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
GO; GO:0043392; P:negative regulation of DNA binding; ISS:UniProtKB.
GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; ISS:UniProtKB.
GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IBA:GO_Central.
GO; GO:0030178; P:negative regulation of Wnt signaling pathway; ISS:UniProtKB.
GO; GO:0060707; P:trophoblast giant cell differentiation; IEA:Ensembl.
InterPro; IPR026134; MDFI/MDFIC.
PANTHER; PTHR15304; PTHR15304; 1.
Pfam; PF15316; MDFI; 1.
1: Evidence at protein level;
Complete proteome; Cytoplasm; Developmental protein; Differentiation;
Nucleus; Reference proteome.
CHAIN 1 246 MyoD family inhibitor.
COMPBIAS 163 243 Cys-rich.
SEQUENCE 246 AA; 25029 MW; 9330E52141B79E5A CRC64;

Related products :

Catalog number Product name Quantity
DL-MyoD-Hu Human Myogenic Differentiation (MyoD) ELISA Kit 96T
DL-MyoD-Ra Rat Myogenic Differentiation (MyoD) ELISA Kit 96T
E9594h Human MyoD Family Inhibitor ELISA Kit 96T
MDGA1 MDFI Gene MyoD family inhibitor
CSB-EL013617HU Human MyoD family inhibitor(MDFI) ELISA kit 96T
MDGA2 MDFIC Gene MyoD family inhibitor domain containing
CSB-EL013617MO Mouse MyoD family inhibitor(MDFI) ELISA kit 96T
E7538h Human MyoD Family Inhibitor Domain Containing Prot 96T
CSB-EL013617MO Mouse MyoD family inhibitor(MDFI) ELISA kit SpeciesMouse 96T
CSB-EL013617HU Human MyoD family inhibitor(MDFI) ELISA kit SpeciesHuman 96T
MDFI_MOUSE ELISA Kit FOR MyoD family inhibitor; organism: Mouse; gene name: Mdfi 96T
CSB-EL013618HU Human MyoD family inhibitor domain-containing protein(MDFIC) ELISA kit 96T
CSB-EL013618MO Mouse MyoD family inhibitor domain-containing protein(MDFIC) ELISA kit 96T
CSB-EL013618MO Mouse MyoD family inhibitor domain-containing protein(MDFIC) ELISA kit SpeciesMouse 96T
CSB-EL013618HU Human MyoD family inhibitor domain-containing protein(MDFIC) ELISA kit SpeciesHuman 96T
E91692Hu ELISA Kit for Myogenic Differentiation (MyoD) 96T/Kit
18-785-210295 MyoD (Ab-200) - Myogenic factor 3; Myf-3 Polyclonal 0.1 mg
GS-0064 MyoD EMSA Kit Myogenic differentiation 1 30
QY-E10229 Rat Myogenic Differentiation(MyoD)ELISA Kit 96T
201-11-1416 Rat Myogenic Differentiation (MyoD)ELISA Kit 96T
18-785-210295 MyoD (Ab-200) - Myogenic factor 3; Myf-3 Polyclonal 0.05 mg
E91692Ra ELISA Kit for Rat Myogenic Differentiation(MyoD) 96T
UB-E10229 Rat Myogenic Differentiation(MyoD)ELISA Kit 96T
GS-0064 MyoD EMSA Kit: Myogenic differentiation 1 30 Reactions
GS-0064 Myogenic differentiation 1, MyoD EMSA Kit 30reactions


GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur

Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur



9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017


france@gentaur.com | Gentaur

Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123

GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U

spain@gentaur.com | Gentaur

ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636

GENTAUR Poland Sp. z o.o.

ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556


Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur