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Myosin light chain 1/3, skeletal muscle isoform (MLC1/MLC3) (MLC1F/MLC3F) (Myosin light chain alkali 1/2) (Myosin light chain A1/A2)

 MYL1_BOVIN              Reviewed;         192 AA.
A0JNJ5; Q29436;
03-APR-2007, integrated into UniProtKB/Swiss-Prot.
12-DEC-2006, sequence version 1.
28-MAR-2018, entry version 74.
RecName: Full=Myosin light chain 1/3, skeletal muscle isoform;
Short=MLC1/MLC3;
Short=MLC1F/MLC3F;
AltName: Full=Myosin light chain alkali 1/2;
Short=Myosin light chain A1/A2;
Name=MYL1 {ECO:0000312|EMBL:AAI26717.1};
Bos taurus (Bovine).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Bovinae; Bos.
NCBI_TaxID=9913;
[1] {ECO:0000312|EMBL:AAI26717.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=Hereford {ECO:0000312|EMBL:AAI26717.1};
TISSUE=Fetal muscle {ECO:0000312|EMBL:AAI26717.1};
NIH - Mammalian Gene Collection (MGC) project;
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000305, ECO:0000312|EMBL:AAA86910.1}
NUCLEOTIDE SEQUENCE [MRNA] OF 25-192.
TISSUE=Longissimus dorsi muscle {ECO:0000312|EMBL:AAA86910.1};
PubMed=7762638;
Smith S.B., Davis S.K., Wilson J.J., Stone R.T., Wu F.Y., Garcia D.K.,
Lunt D.K., Schiavetta A.M.;
"Bovine fast-twitch myosin light chain 1: cloning and mRNA amount in
muscle of cattle treated with clenbuterol.";
Am. J. Physiol. 268:E858-E865(1995).
-!- FUNCTION: Regulatory light chain of myosin. Does not bind calcium.
{ECO:0000305}.
-!- SUBUNIT: Myosin is a hexamer of 2 heavy chains and 4 light chains.
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EMBL; BC126716; AAI26717.1; -; mRNA.
EMBL; U45430; AAA86910.1; -; mRNA.
RefSeq; NP_001073046.1; NM_001079578.1.
RefSeq; XP_005202773.1; XM_005202716.2.
UniGene; Bt.109731; -.
ProteinModelPortal; A0JNJ5; -.
SMR; A0JNJ5; -.
STRING; 9913.ENSBTAP00000049636; -.
PaxDb; A0JNJ5; -.
PRIDE; A0JNJ5; -.
Ensembl; ENSBTAT00000054271; ENSBTAP00000049636; ENSBTAG00000009707.
GeneID; 317657; -.
KEGG; bta:317657; -.
CTD; 4632; -.
VGNC; VGNC:31799; MYL1.
eggNOG; KOG0030; Eukaryota.
eggNOG; COG5126; LUCA.
GeneTree; ENSGT00590000082921; -.
HOGENOM; HOG000233018; -.
HOVERGEN; HBG012180; -.
InParanoid; A0JNJ5; -.
KO; K05738; -.
OMA; TNAEINK; -.
OrthoDB; EOG091G0TQL; -.
TreeFam; TF351553; -.
Reactome; R-BTA-390522; Striated Muscle Contraction.
Proteomes; UP000009136; Chromosome 2.
Bgee; ENSBTAG00000009707; -.
GO; GO:0030016; C:myofibril; IEA:Ensembl.
GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
GO; GO:0006936; P:muscle contraction; IEA:Ensembl.
CDD; cd00051; EFh; 1.
InterPro; IPR011992; EF-hand-dom_pair.
InterPro; IPR002048; EF_hand_dom.
SMART; SM00054; EFh; 2.
SUPFAM; SSF47473; SSF47473; 1.
PROSITE; PS50222; EF_HAND_2; 3.
2: Evidence at transcript level;
Complete proteome; Methylation; Motor protein; Muscle protein; Myosin;
Phosphoprotein; Reference proteome; Repeat.
INIT_MET 1 1 Removed. {ECO:0000250|UniProtKB:P02602}.
CHAIN 2 192 Myosin light chain 1/3, skeletal muscle
isoform.
/FTId=PRO_0000283742.
DOMAIN 48 83 EF-hand 1. {ECO:0000255|PROSITE-
ProRule:PRU00448}.
DOMAIN 125 160 EF-hand 2. {ECO:0000255|PROSITE-
ProRule:PRU00448}.
DOMAIN 160 192 EF-hand 3. {ECO:0000255|PROSITE-
ProRule:PRU00448}.
MOD_RES 2 2 N,N,N-trimethylalanine.
{ECO:0000250|UniProtKB:P02602}.
MOD_RES 69 69 Phosphothreonine.
{ECO:0000250|UniProtKB:P02600}.
MOD_RES 71 71 Phosphoserine.
{ECO:0000250|UniProtKB:P02600}.
MOD_RES 85 85 Phosphothreonine.
{ECO:0000250|UniProtKB:P02600}.
MOD_RES 97 97 Phosphoserine.
{ECO:0000250|UniProtKB:P02600}.
CONFLICT 110 110 Q -> E (in Ref. 2; AAA86910).
{ECO:0000305}.
SEQUENCE 192 AA; 20932 MW; EF12E3D0BC90BACC CRC64;
MAPKKDVKKP AAAAAPAPAP APAPAPAPAP PKEEKIDLSA IKIEFSKQQQ DEFKEAFLLF
DRTGECKITL SQVGDVLRAL GTNPTNAEVK KVLGNPSNEE MNAKKIEFEQ FLPMLQAISN
NKDQGTYEDF VEGLRVFDKE GNGTVMGAEL RHVLATLGEK MKEEEVEALM AGQEDSNGCI
NYEAFVKHIM SN


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