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N5-carboxyaminoimidazole ribonucleotide mutase (N5-CAIR mutase) (EC 5.4.99.18) (5-(carboxyamino)imidazole ribonucleotide mutase)

 A0A064C425_STREE        Unreviewed;       162 AA.
A0A064C425;
03-SEP-2014, integrated into UniProtKB/TrEMBL.
03-SEP-2014, sequence version 1.
20-JUN-2018, entry version 44.
RecName: Full=N5-carboxyaminoimidazole ribonucleotide mutase {ECO:0000256|HAMAP-Rule:MF_01929, ECO:0000256|PIRNR:PIRNR001338};
Short=N5-CAIR mutase {ECO:0000256|HAMAP-Rule:MF_01929, ECO:0000256|PIRNR:PIRNR001338};
EC=5.4.99.18 {ECO:0000256|HAMAP-Rule:MF_01929, ECO:0000256|PIRNR:PIRNR001338};
AltName: Full=5-(carboxyamino)imidazole ribonucleotide mutase {ECO:0000256|HAMAP-Rule:MF_01929};
Name=purE_1 {ECO:0000313|EMBL:CRH98750.1};
Synonyms=purE {ECO:0000256|HAMAP-Rule:MF_01929,
ECO:0000313|EMBL:AJD71021.1}, purE_2 {ECO:0000313|EMBL:CGF79604.1},
purE_3 {ECO:0000313|EMBL:COJ34095.1};
ORFNames=A4260_01420 {ECO:0000313|EMBL:OCQ82641.1},
A5N45_06690 {ECO:0000313|EMBL:OYL28423.1},
AWW74_07440 {ECO:0000313|EMBL:KWX84276.1},
AZJ05_06310 {ECO:0000313|EMBL:PLV78947.1},
AZJ08_09110 {ECO:0000313|EMBL:PLV70150.1},
AZJ10_01560 {ECO:0000313|EMBL:PLV77398.1},
AZJ11_04860 {ECO:0000313|EMBL:PLV87279.1},
AZJ13_01225 {ECO:0000313|EMBL:PLV76623.1},
AZJ14_01210 {ECO:0000313|EMBL:PLV95632.1},
AZJ15_08730 {ECO:0000313|EMBL:PLV68735.1},
AZJ16_00230 {ECO:0000313|EMBL:PLV67234.1},
AZJ17_04590 {ECO:0000313|EMBL:PLV98188.1},
AZJ18_02775 {ECO:0000313|EMBL:PLV92320.1},
AZJ19_01755 {ECO:0000313|EMBL:PLV88364.1},
AZJ20_03855 {ECO:0000313|EMBL:PLV86754.1},
AZJ80_04210 {ECO:0000313|EMBL:PLV82190.1},
AZK24_06060 {ECO:0000313|EMBL:PLV93761.1},
C4N11_00345 {ECO:0000313|EMBL:AVD76112.1},
CHL72_03060 {ECO:0000313|EMBL:OZS33056.1},
CHL73_07245 {ECO:0000313|EMBL:OZS29697.1},
CWI64_07240 {ECO:0000313|EMBL:AUB34161.1},
ERS003549_01686 {ECO:0000313|EMBL:CZE19321.1},
ERS019166_01068 {ECO:0000313|EMBL:CIO39064.1},
ERS019416_01470 {ECO:0000313|EMBL:CIX11820.1},
ERS019420_01394 {ECO:0000313|EMBL:CIW93064.1},
ERS019499_00574 {ECO:0000313|EMBL:CIS90083.1},
ERS019687_00602 {ECO:0000313|EMBL:CIV65678.1},
ERS019694_00462 {ECO:0000313|EMBL:CGF51030.1},
ERS020408_01102 {ECO:0000313|EMBL:CIX26307.1},
ERS020491_00243 {ECO:0000313|EMBL:CGF75981.1},
ERS020491_00998 {ECO:0000313|EMBL:CGF79604.1},
ERS020526_02540 {ECO:0000313|EMBL:COQ09447.1},
ERS020534_01634 {ECO:0000313|EMBL:COP23007.1},
ERS020822_01418 {ECO:0000313|EMBL:COI62371.1},
ERS020822_03428 {ECO:0000313|EMBL:COJ34095.1},
ERS020827_01298 {ECO:0000313|EMBL:COI80282.1},
ERS020831_01410 {ECO:0000313|EMBL:CJF38290.1},
ERS021057_01364 {ECO:0000313|EMBL:CEV47486.1},
ERS021218_01541 {ECO:0000313|EMBL:COR74259.1},
ERS021300_01449 {ECO:0000313|EMBL:CJF60931.1},
ERS021354_06823 {ECO:0000313|EMBL:CJH78550.1},
ERS021360_00517 {ECO:0000313|EMBL:CIZ86897.1},
ERS021368_00670 {ECO:0000313|EMBL:CEY62463.1},
ERS021449_01250 {ECO:0000313|EMBL:CJC06290.1},
ERS021629_05928 {ECO:0000313|EMBL:CJK05516.1},
ERS021634_05692 {ECO:0000313|EMBL:CJJ88217.1},
ERS021733_03765 {ECO:0000313|EMBL:CJS46340.1},
ERS021762_01577 {ECO:0000313|EMBL:CKB16073.1},
ERS021858_00766 {ECO:0000313|EMBL:CJT72775.1},
ERS022045_04216 {ECO:0000313|EMBL:CJL83952.1},
ERS022071_01446 {ECO:0000313|EMBL:CJP77335.1},
ERS022199_00683 {ECO:0000313|EMBL:CJM37158.1},
ERS022363_00330 {ECO:0000313|EMBL:CJV64806.1},
ERS022390_01057 {ECO:0000313|EMBL:CJV34696.1},
ERS044004_02458 {ECO:0000313|EMBL:CTF76966.1},
ERS068943_00828 {ECO:0000313|EMBL:CMV53438.1},
ERS232495_05511 {ECO:0000313|EMBL:CKG28345.1},
ERS232497_00045 {ECO:0000313|EMBL:CKE26680.1},
ERS232498_00810 {ECO:0000313|EMBL:CKE59964.1},
ERS232499_01476 {ECO:0000313|EMBL:CKF00804.1},
ERS232505_03330 {ECO:0000313|EMBL:CKF45075.1},
ERS232508_00709 {ECO:0000313|EMBL:CRH98750.1},
ERS367337_01253 {ECO:0000313|EMBL:CWE64303.1},
ERS409064_01520 {ECO:0000313|EMBL:CVT22176.1},
ERS558328_01805 {ECO:0000313|EMBL:CYO97518.1},
NTPn46_04835 {ECO:0000313|EMBL:KXW44889.1},
SAMEA1026615_01847 {ECO:0000313|EMBL:SNJ16829.1},
SAMEA2626854_00865 {ECO:0000313|EMBL:SNP67424.1},
SpnNT_00080 {ECO:0000313|EMBL:AJD71021.1};
Streptococcus pneumoniae.
Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
Streptococcus.
NCBI_TaxID=1313 {ECO:0000313|EMBL:CRH98750.1, ECO:0000313|Proteomes:UP000040381};
[1] {ECO:0000313|EMBL:AJD71021.1, ECO:0000313|Proteomes:UP000031393}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=NT_110_58 {ECO:0000313|EMBL:AJD71021.1,
ECO:0000313|Proteomes:UP000031393};
PubMed=25480686; DOI=10.1093/gbe/evu263;
Hilty M., Wuthrich D., Salter S.J., Engel H., Campbell S., Sa-Leao R.,
de Lencastre H., Hermans P., Sadowy E., Turner P., Chewapreecha C.,
Diggle M., Pluschke G., McGee L., Koseoglu Eser O., Low D.E.,
Smith-Vaughan H., Endimiani A., Kuffer M., Dupasquier M.,
Beaudoing E., Weber J., Bruggmann R., Hanage W.P., Parkhill J.,
Hathaway L.J., Muhlemann K., Bentley S.D.;
"Global Phylogenomic Analysis of Nonencapsulated Streptococcus
pneumoniae Reveals a Deep-Branching Classic Lineage That Is Distinct
from Multiple Sporadic Lineages.";
Genome Biol. Evol. 6:3281-3294(2014).
[2] {ECO:0000313|Proteomes:UP000038546, ECO:0000313|Proteomes:UP000039153, ECO:0000313|Proteomes:UP000039303}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=14 {ECO:0000313|EMBL:CKE59964.1,
ECO:0000313|Proteomes:UP000048466}, 19B {ECO:0000313|EMBL:CIX26307.1,
ECO:0000313|Proteomes:UP000046154}, 37 {ECO:0000313|EMBL:CIS90083.1,
ECO:0000313|Proteomes:UP000040885}, 38 {ECO:0000313|EMBL:CKE26680.1,
ECO:0000313|Proteomes:UP000044473},
S-166 {ECO:0000313|EMBL:CMV53438.1,
ECO:0000313|Proteomes:UP000040682},
SMRU1016 {ECO:0000313|EMBL:COQ09447.1,
ECO:0000313|Proteomes:UP000235432},
SMRU1024 {ECO:0000313|EMBL:COP23007.1,
ECO:0000313|Proteomes:UP000044969},
SMRU1312 {ECO:0000313|EMBL:COI62371.1,
ECO:0000313|Proteomes:UP000043880},
SMRU1317 {ECO:0000313|EMBL:COI80282.1,
ECO:0000313|Proteomes:UP000039153},
SMRU1321 {ECO:0000313|EMBL:CJF38290.1,
ECO:0000313|Proteomes:UP000040650},
SMRU1547 {ECO:0000313|EMBL:CEV47486.1,
ECO:0000313|Proteomes:UP000048265},
SMRU1708 {ECO:0000313|EMBL:COR74259.1,
ECO:0000313|Proteomes:UP000046095},
SMRU1790 {ECO:0000313|EMBL:CJF60931.1,
ECO:0000313|Proteomes:UP000045409},
SMRU1844 {ECO:0000313|EMBL:CJH78550.1,
ECO:0000313|Proteomes:UP000040775},
SMRU1850 {ECO:0000313|EMBL:CIZ86897.1,
ECO:0000313|Proteomes:UP000044493},
SMRU1858 {ECO:0000313|EMBL:CEY62463.1,
ECO:0000313|Proteomes:UP000046964},
SMRU1939 {ECO:0000313|EMBL:CJC06290.1,
ECO:0000313|Proteomes:UP000039303},
SMRU2119 {ECO:0000313|EMBL:CJK05516.1,
ECO:0000313|Proteomes:UP000042476},
SMRU2224 {ECO:0000313|EMBL:CJS46340.1,
ECO:0000313|Proteomes:UP000041439},
SMRU2253 {ECO:0000313|EMBL:CKB16073.1,
ECO:0000313|Proteomes:UP000044836},
SMRU2349 {ECO:0000313|EMBL:CJT72775.1,
ECO:0000313|Proteomes:UP000042664},
SMRU2535 {ECO:0000313|EMBL:CJL83952.1,
ECO:0000313|Proteomes:UP000043492},
SMRU2561 {ECO:0000313|EMBL:CJP77335.1,
ECO:0000313|Proteomes:UP000039956},
SMRU258 {ECO:0000313|EMBL:CIX11820.1,
ECO:0000313|Proteomes:UP000043857},
SMRU262 {ECO:0000313|EMBL:CIW93064.1,
ECO:0000313|Proteomes:UP000042694},
SMRU2689 {ECO:0000313|EMBL:CJM37158.1,
ECO:0000313|Proteomes:UP000044638},
SMRU2853 {ECO:0000313|EMBL:CJV64806.1,
ECO:0000313|Proteomes:UP000045067},
SMRU2880 {ECO:0000313|EMBL:CJV34696.1,
ECO:0000313|Proteomes:UP000039440},
SMRU341 {ECO:0000313|EMBL:CIS90083.1},
SMRU529 {ECO:0000313|EMBL:CIV65678.1,
ECO:0000313|Proteomes:UP000041567},
SMRU536 {ECO:0000313|EMBL:CGF51030.1,
ECO:0000313|Proteomes:UP000047707},
SMRU8 {ECO:0000313|EMBL:CIO39064.1},
SMRU898 {ECO:0000313|EMBL:CIX26307.1},
SMRU981 {ECO:0000313|EMBL:CGF75981.1,
ECO:0000313|Proteomes:UP000047188},
Type strain: N {ECO:0000313|EMBL:CIO39064.1}, and
type strain: N {ECO:0000313|Proteomes:UP000038546,
ECO:0000313|Proteomes:UP000039362};
Murphy D.;
Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|EMBL:CRH98750.1, ECO:0000313|Proteomes:UP000040381}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=14 {ECO:0000313|EMBL:CRH98750.1,
ECO:0000313|Proteomes:UP000040381};
Informatics Pathogen;
Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
[4] {ECO:0000313|EMBL:CTF76966.1, ECO:0000313|Proteomes:UP000045142}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=R34-3199 {ECO:0000313|EMBL:CTF76966.1,
ECO:0000313|Proteomes:UP000045142};
Informatics Pathogen;
Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
[5] {ECO:0000313|EMBL:KXW44889.1, ECO:0000313|Proteomes:UP000075530}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=NTPn 46 {ECO:0000313|EMBL:KXW44889.1,
ECO:0000313|Proteomes:UP000075530};
Mohale T., Wolter N., Allam M., Du Plessis M., Von Gottberg A.;
"Invasive nontypeable pneumococci in South Africa.";
Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
[6] {ECO:0000313|EMBL:KWX84276.1, ECO:0000313|Proteomes:UP000070671}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=225994 {ECO:0000313|EMBL:KWX84276.1,
ECO:0000313|Proteomes:UP000070671};
Bisharat N.;
"Levofloxacin resistant Streptococcus pneumoniae.";
Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
[7] {ECO:0000313|Proteomes:UP000234783, ECO:0000313|Proteomes:UP000234868, ECO:0000313|Proteomes:UP000234890}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=NTPn 101 {ECO:0000313|EMBL:PLV68735.1,
ECO:0000313|Proteomes:UP000234900},
NTPn 117 {ECO:0000313|EMBL:PLV76623.1,
ECO:0000313|Proteomes:UP000235003},
NTPn 152 {ECO:0000313|EMBL:PLV82190.1,
ECO:0000313|Proteomes:UP000234783},
NTPn 181 {ECO:0000313|EMBL:PLV87279.1,
ECO:0000313|Proteomes:UP000234916},
NTPn 228 {ECO:0000313|EMBL:PLV93761.1,
ECO:0000313|Proteomes:UP000234890}, and
NTPn 231 {ECO:0000313|EMBL:PLV95632.1,
ECO:0000313|Proteomes:UP000234868};
Mohale T., Wolter N., Allam M., Nzenze S., Madhi S., Du Plessis M.,
Von Gottberg A.;
"Carriage nontypeable pneumococci in South Africa.";
Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
[8] {ECO:0000313|Proteomes:UP000071227, ECO:0000313|Proteomes:UP000071938, ECO:0000313|Proteomes:UP000072289}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=2245STDY5982743 {ECO:0000313|EMBL:CYO97518.1,
ECO:0000313|Proteomes:UP000071938},
2842STDY5643896 {ECO:0000313|EMBL:CWE64303.1,
ECO:0000313|Proteomes:UP000071227},
2842STDY5753281 {ECO:0000313|EMBL:CVT22176.1,
ECO:0000313|Proteomes:UP000074995}, and
A33096 {ECO:0000313|EMBL:CZE19321.1,
ECO:0000313|Proteomes:UP000072289};
Pathogen Informatics;
Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
[9] {ECO:0000313|Proteomes:UP000234762, ECO:0000313|Proteomes:UP000234831, ECO:0000313|Proteomes:UP000234866}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=NTPn 119 {ECO:0000313|EMBL:PLV78947.1,
ECO:0000313|Proteomes:UP000235102},
NTPn 124 {ECO:0000313|EMBL:PLV77398.1,
ECO:0000313|Proteomes:UP000235048},
NTPn 154 {ECO:0000313|EMBL:PLV88364.1,
ECO:0000313|Proteomes:UP000234831},
NTPn 158 {ECO:0000313|EMBL:PLV86754.1,
ECO:0000313|Proteomes:UP000234762},
NTPn 183 {ECO:0000313|EMBL:PLV92320.1,
ECO:0000313|Proteomes:UP000235045},
NTPn 239 {ECO:0000313|EMBL:PLV98188.1,
ECO:0000313|Proteomes:UP000235012},
NTPn 85 {ECO:0000313|EMBL:PLV67234.1,
ECO:0000313|Proteomes:UP000234988}, and
NTPn 90 {ECO:0000313|EMBL:PLV70150.1,
ECO:0000313|Proteomes:UP000234866};
Wen L., He K., Yang H.;
Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
[10] {ECO:0000313|EMBL:OCQ82641.1, ECO:0000313|Proteomes:UP000093517}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=39286 {ECO:0000313|EMBL:OCQ82641.1,
ECO:0000313|Proteomes:UP000093517};
Ndlangisa K., Du Plessis M., Von Gottberg A.;
"Invasive disease caused simultaneously by more than one serotype of
Streptococcus pneumoniae, South Africa.";
Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
[11] {ECO:0000313|EMBL:SNJ16829.1, ECO:0000313|Proteomes:UP000197833, ECO:0000313|Proteomes:UP000198094}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=3063STDY5801795 {ECO:0000313|EMBL:SNP67424.1,
ECO:0000313|Proteomes:UP000197833}, and
UoS3267 {ECO:0000313|EMBL:SNJ16829.1,
ECO:0000313|Proteomes:UP000198094};
Pathogen Informatics;
Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
[12] {ECO:0000313|EMBL:OYL28423.1, ECO:0000313|Proteomes:UP000214939}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=8227-15B {ECO:0000313|EMBL:OYL28423.1,
ECO:0000313|Proteomes:UP000214939};
Ndlangisa K., Du Plessis M., Von Gottberg A.;
"Invasive disease caused simultaneously by more than one serotype of
Streptococcus pneumoniae, South Africa.";
Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
[13] {ECO:0000313|EMBL:OZS29697.1, ECO:0000313|Proteomes:UP000216187, ECO:0000313|Proteomes:UP000216248}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=20893-6B {ECO:0000313|EMBL:OZS29697.1,
ECO:0000313|Proteomes:UP000216187}, and
8788-23F {ECO:0000313|EMBL:OZS33056.1,
ECO:0000313|Proteomes:UP000216248};
Ndlangisa K., Du Plessis M., Von Gottberg A.;
"Invasive disease caused simultaneously by more than one serotype of
Streptococcus pneumoniae.";
Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
[14] {ECO:0000313|EMBL:AUB34161.1, ECO:0000313|Proteomes:UP000232067}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=19F {ECO:0000313|EMBL:AUB34161.1,
ECO:0000313|Proteomes:UP000232067};
Han C.G.;
Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
[15] {ECO:0000313|EMBL:AVD76112.1, ECO:0000313|Proteomes:UP000238028}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=335 {ECO:0000313|EMBL:AVD76112.1,
ECO:0000313|Proteomes:UP000238028};
Cohen D.B., Kent A.D.;
Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Catalyzes the conversion of N5-carboxyaminoimidazole
ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole
ribonucleotide (CAIR). {ECO:0000256|HAMAP-Rule:MF_01929,
ECO:0000256|PIRNR:PIRNR001338}.
-!- CATALYTIC ACTIVITY: 5-carboxyamino-1-(5-phospho-D-
ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-
carboxylate. {ECO:0000256|HAMAP-Rule:MF_01929,
ECO:0000256|PIRNR:PIRNR001338}.
-!- PATHWAY: Purine metabolism; IMP biosynthesis via de novo pathway;
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-
amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.
{ECO:0000256|HAMAP-Rule:MF_01929, ECO:0000256|PIRNR:PIRNR001338}.
-!- SIMILARITY: Belongs to the AIR carboxylase family. Class I
subfamily. {ECO:0000256|HAMAP-Rule:MF_01929}.
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EMBL; CP007593; AJD71021.1; -; Genomic_DNA.
EMBL; CP025076; AUB34161.1; -; Genomic_DNA.
EMBL; CP026670; AVD76112.1; -; Genomic_DNA.
EMBL; CFBA01000018; CEV47486.1; -; Genomic_DNA.
EMBL; CFGX01000006; CEY62463.1; -; Genomic_DNA.
EMBL; CHOP01000096; CGF51030.1; -; Genomic_DNA.
EMBL; CHOW01000002; CGF75981.1; -; Genomic_DNA.
EMBL; CHOW01000009; CGF79604.1; -; Genomic_DNA.
EMBL; CKAB01000014; CIO39064.1; -; Genomic_DNA.
EMBL; CKHR01000005; CIS90083.1; -; Genomic_DNA.
EMBL; CKLU01000219; CIV65678.1; -; Genomic_DNA.
EMBL; CKOB01000016; CIW93064.1; -; Genomic_DNA.
EMBL; CKOI01000018; CIX11820.1; -; Genomic_DNA.
EMBL; CKOR01000010; CIX26307.1; -; Genomic_DNA.
EMBL; CKTJ01000005; CIZ86897.1; -; Genomic_DNA.
EMBL; CKVP01000013; CJC06290.1; -; Genomic_DNA.
EMBL; CLAW01000029; CJF38290.1; -; Genomic_DNA.
EMBL; CLBL01000017; CJF60931.1; -; Genomic_DNA.
EMBL; CLCG01000046; CJH78550.1; -; Genomic_DNA.
EMBL; CLFU01000058; CJJ88217.1; -; Genomic_DNA.
EMBL; CLGJ01000048; CJK05516.1; -; Genomic_DNA.
EMBL; CLJU01000031; CJL83952.1; -; Genomic_DNA.
EMBL; CLMB01000008; CJM37158.1; -; Genomic_DNA.
EMBL; CLRF01000015; CJP77335.1; -; Genomic_DNA.
EMBL; CLUP01000060; CJS46340.1; -; Genomic_DNA.
EMBL; CLYF01000011; CJT72775.1; -; Genomic_DNA.
EMBL; CMAP01000015; CJV34696.1; -; Genomic_DNA.
EMBL; CMBJ01000007; CJV64806.1; -; Genomic_DNA.
EMBL; CMJQ01000047; CKB16073.1; -; Genomic_DNA.
EMBL; CMPS01000001; CKE26680.1; -; Genomic_DNA.
EMBL; CIIO01000028; CKE59964.1; -; Genomic_DNA.
EMBL; CMQD01000027; CKF00804.1; -; Genomic_DNA.
EMBL; CIDG01000102; CKF45075.1; -; Genomic_DNA.
EMBL; CMPU01000450; CKG28345.1; -; Genomic_DNA.
EMBL; CPMI01000182; CMV53438.1; -; Genomic_DNA.
EMBL; CRHY01000007; COI62371.1; -; Genomic_DNA.
EMBL; CRII01000014; COI80282.1; -; Genomic_DNA.
EMBL; CRHY01000034; COJ34095.1; -; Genomic_DNA.
EMBL; CRRL01000030; COP23007.1; -; Genomic_DNA.
EMBL; CRSC01000009; COQ09447.1; -; Genomic_DNA.
EMBL; CRVC01000020; COR74259.1; -; Genomic_DNA.
EMBL; CVOG01000011; CRH98750.1; -; Genomic_DNA.
EMBL; CNRG02000017; CTF76966.1; -; Genomic_DNA.
EMBL; FDEX01000012; CVT22176.1; -; Genomic_DNA.
EMBL; FEBA01000009; CWE64303.1; -; Genomic_DNA.
EMBL; FHVI01000018; CYO97518.1; -; Genomic_DNA.
EMBL; FIYJ01000013; CZE19321.1; -; Genomic_DNA.
EMBL; LRSN01000024; KWX84276.1; -; Genomic_DNA.
EMBL; LJWP01000010; KXW44889.1; -; Genomic_DNA.
EMBL; LWGW01000064; OCQ82641.1; -; Genomic_DNA.
EMBL; NNBW01000087; OYL28423.1; -; Genomic_DNA.
EMBL; NOIL01000045; OZS29697.1; -; Genomic_DNA.
EMBL; NOIM01000133; OZS33056.1; -; Genomic_DNA.
EMBL; LTCF01000084; PLV67234.1; -; Genomic_DNA.
EMBL; LTCI01000189; PLV68735.1; -; Genomic_DNA.
EMBL; LTCG01000061; PLV70150.1; -; Genomic_DNA.
EMBL; LTCJ01000002; PLV76623.1; -; Genomic_DNA.
EMBL; LTCL01000046; PLV77398.1; -; Genomic_DNA.
EMBL; LTCK01000007; PLV78947.1; -; Genomic_DNA.
EMBL; LTCO01000114; PLV82190.1; -; Genomic_DNA.
EMBL; LTCQ01000230; PLV86754.1; -; Genomic_DNA.
EMBL; LTCR01000099; PLV87279.1; -; Genomic_DNA.
EMBL; LTCP01000057; PLV88364.1; -; Genomic_DNA.
EMBL; LTCW01000110; PLV92320.1; -; Genomic_DNA.
EMBL; LTCT01000135; PLV93761.1; -; Genomic_DNA.
EMBL; LTCU01000220; PLV95632.1; -; Genomic_DNA.
EMBL; LTCV01000117; PLV98188.1; -; Genomic_DNA.
EMBL; FYQS01000027; SNJ16829.1; -; Genomic_DNA.
EMBL; FZDQ01000008; SNP67424.1; -; Genomic_DNA.
RefSeq; WP_000805601.1; NZ_PIZF01000012.1.
EnsemblBacteria; AJD71021; AJD71021; SpnNT_00080.
EnsemblBacteria; CEV47486; CEV47486; ERS021057_01364.
EnsemblBacteria; CEW70500; CEW70500; ERS021528_01651.
EnsemblBacteria; CEY62463; CEY62463; ERS021368_00670.
EnsemblBacteria; CFP92039; CFP92039; ERS013931_01156.
EnsemblBacteria; CGF01214; CGF01214; ERS019473_01340.
EnsemblBacteria; CGF51030; CGF51030; ERS019694_00462.
EnsemblBacteria; CGF75981; CGF75981; ERS020491_00243.
EnsemblBacteria; CGF79604; CGF79604; ERS020491_00998.
EnsemblBacteria; CIO39064; CIO39064; ERS019166_01068.
EnsemblBacteria; CIS90083; CIS90083; ERS019499_00574.
EnsemblBacteria; CIT88595; CIT88595; ERS019595_01062.
EnsemblBacteria; CIV65678; CIV65678; ERS019687_00602.
EnsemblBacteria; CIW93064; CIW93064; ERS019420_01394.
EnsemblBacteria; CIX11820; CIX11820; ERS019416_01470.
EnsemblBacteria; CIX26307; CIX26307; ERS020408_01102.
EnsemblBacteria; CIZ86897; CIZ86897; ERS021360_00517.
EnsemblBacteria; CJC06290; CJC06290; ERS021449_01250.
EnsemblBacteria; CJF38290; CJF38290; ERS020831_01410.
EnsemblBacteria; CJF60931; CJF60931; ERS021300_01449.
EnsemblBacteria; CJH78550; CJH78550; ERS021354_06823.
EnsemblBacteria; CJJ88217; CJJ88217; ERS021634_05692.
EnsemblBacteria; CJK05516; CJK05516; ERS021629_05928.
EnsemblBacteria; CJK32957; CJK32957; ERS022016_01292.
EnsemblBacteria; CJL83952; CJL83952; ERS022045_04216.
EnsemblBacteria; CJM37158; CJM37158; ERS022199_00683.
EnsemblBacteria; CJP77335; CJP77335; ERS022071_01446.
EnsemblBacteria; CJS46340; CJS46340; ERS021733_03765.
EnsemblBacteria; CJT72775; CJT72775; ERS021858_00766.
EnsemblBacteria; CJV34696; CJV34696; ERS022390_01057.
EnsemblBacteria; CJV64806; CJV64806; ERS022363_00330.
EnsemblBacteria; CJY33559; CJY33559; ERS022329_00972.
EnsemblBacteria; CJY46426; CJY46426; ERS022329_01414.
EnsemblBacteria; CKA41467; CKA41467; ERS022522_01546.
EnsemblBacteria; CKB16073; CKB16073; ERS021762_01577.
EnsemblBacteria; CKD51492; CKD51492; ERS232442_01374.
EnsemblBacteria; CKE26680; CKE26680; ERS232497_00045.
EnsemblBacteria; CKE59964; CKE59964; ERS232498_00810.
EnsemblBacteria; CKF00577; CKF00577; ERS232512_01640.
EnsemblBacteria; CKF00804; CKF00804; ERS232499_01476.
EnsemblBacteria; CKF30516; CKF30516; ERS232524_00469.
EnsemblBacteria; CKG28345; CKG28345; ERS232495_05511.
EnsemblBacteria; CMV53438; CMV53438; ERS068943_00828.
EnsemblBacteria; CMX03537; CMX03537; ERS077238_01400.
EnsemblBacteria; CNA82093; CNA82093; ERS077235_01538.
EnsemblBacteria; CNB06942; CNB06942; ERS077244_01489.
EnsemblBacteria; CNZ55950; CNZ55950; ERS020881_00172.
EnsemblBacteria; COI62371; COI62371; ERS020822_01418.
EnsemblBacteria; COI80282; COI80282; ERS020827_01298.
EnsemblBacteria; COJ34095; COJ34095; ERS020822_03428.
EnsemblBacteria; COP23007; COP23007; ERS020534_01634.
EnsemblBacteria; COR74259; COR74259; ERS021218_01541.
EnsemblBacteria; CRF97850; CRF97850; ERS020526_01701.
EnsemblBacteria; CRH98750; CRH98750; ERS232508_00709.
EnsemblBacteria; CTD89879; CTD89879; ERS044129_02666.
EnsemblBacteria; CTF76966; CTF76966; ERS044004_02458.
EnsemblBacteria; CVO77484; CVO77484; ERS408893_01482.
EnsemblBacteria; CVO96601; CVO96601; ERS367764_00942.
EnsemblBacteria; CVQ00780; CVQ00780; ERS515225_00223.
EnsemblBacteria; CVT22176; CVT22176; ERS409064_01520.
EnsemblBacteria; CVT96391; CVT96391; ERS409105_01410.
EnsemblBacteria; CVV11723; CVV11723; ERS409165_01846.
EnsemblBacteria; CVY61028; CVY61028; ERS409372_00035.
EnsemblBacteria; CWE64303; CWE64303; ERS367337_01253.
EnsemblBacteria; CWH17414; CWH17414; ERS408871_01755.
EnsemblBacteria; CWL95461; CWL95461; ERS515182_00675.
EnsemblBacteria; CYL99381; CYL99381; ERS455085_01748.
EnsemblBacteria; CYO97518; CYO97518; ERS558328_01805.
EnsemblBacteria; CZE19321; CZE19321; ERS003549_01686.
EnsemblBacteria; KWX84276; KWX84276; AWW74_07440.
EnsemblBacteria; KXW44889; KXW44889; NTPn46_04835.
EnsemblBacteria; OCQ82641; OCQ82641; A4260_01420.
PATRIC; fig|1313.13073.peg.88; -.
eggNOG; ENOG4108UM6; Bacteria.
eggNOG; COG0041; LUCA.
UniPathway; UPA00074; UER00943.
Proteomes; UP000031393; Chromosome.
Proteomes; UP000038546; Unassembled WGS sequence.
Proteomes; UP000039153; Unassembled WGS sequence.
Proteomes; UP000039303; Unassembled WGS sequence.
Proteomes; UP000039362; Unassembled WGS sequence.
Proteomes; UP000039440; Unassembled WGS sequence.
Proteomes; UP000039956; Unassembled WGS sequence.
Proteomes; UP000040381; Unassembled WGS sequence.
Proteomes; UP000040650; Unassembled WGS sequence.
Proteomes; UP000040682; Unassembled WGS sequence.
Proteomes; UP000040775; Unassembled WGS sequence.
Proteomes; UP000040885; Unassembled WGS sequence.
Proteomes; UP000041439; Unassembled WGS sequence.
Proteomes; UP000041567; Unassembled WGS sequence.
Proteomes; UP000042476; Unassembled WGS sequence.
Proteomes; UP000042664; Unassembled WGS sequence.
Proteomes; UP000042694; Unassembled WGS sequence.
Proteomes; UP000043492; Unassembled WGS sequence.
Proteomes; UP000043857; Unassembled WGS sequence.
Proteomes; UP000043880; Unassembled WGS sequence.
Proteomes; UP000044197; Unassembled WGS sequence.
Proteomes; UP000044473; Unassembled WGS sequence.
Proteomes; UP000044493; Unassembled WGS sequence.
Proteomes; UP000044638; Unassembled WGS sequence.
Proteomes; UP000044836; Unassembled WGS sequence.
Proteomes; UP000044969; Unassembled WGS sequence.
Proteomes; UP000045067; Unassembled WGS sequence.
Proteomes; UP000045142; Unassembled WGS sequence.
Proteomes; UP000045409; Unassembled WGS sequence.
Proteomes; UP000046095; Unassembled WGS sequence.
Proteomes; UP000046154; Unassembled WGS sequence.
Proteomes; UP000046356; Unassembled WGS sequence.
Proteomes; UP000046964; Unassembled WGS sequence.
Proteomes; UP000047188; Unassembled WGS sequence.
Proteomes; UP000047707; Unassembled WGS sequence.
Proteomes; UP000048265; Unassembled WGS sequence.
Proteomes; UP000048466; Unassembled WGS sequence.
Proteomes; UP000070671; Unassembled WGS sequence.
Proteomes; UP000071227; Unassembled WGS sequence.
Proteomes; UP000071938; Unassembled WGS sequence.
Proteomes; UP000072289; Unassembled WGS sequence.
Proteomes; UP000074995; Unassembled WGS sequence.
Proteomes; UP000075530; Unassembled WGS sequence.
Proteomes; UP000093517; Unassembled WGS sequence.
Proteomes; UP000197833; Unassembled WGS sequence.
Proteomes; UP000198094; Unassembled WGS sequence.
Proteomes; UP000214939; Unassembled WGS sequence.
Proteomes; UP000216187; Unassembled WGS sequence.
Proteomes; UP000216248; Unassembled WGS sequence.
Proteomes; UP000232067; Chromosome.
Proteomes; UP000234762; Unassembled WGS sequence.
Proteomes; UP000234783; Unassembled WGS sequence.
Proteomes; UP000234831; Unassembled WGS sequence.
Proteomes; UP000234866; Unassembled WGS sequence.
Proteomes; UP000234868; Unassembled WGS sequence.
Proteomes; UP000234890; Unassembled WGS sequence.
Proteomes; UP000234900; Unassembled WGS sequence.
Proteomes; UP000234916; Unassembled WGS sequence.
Proteomes; UP000234988; Unassembled WGS sequence.
Proteomes; UP000235003; Unassembled WGS sequence.
Proteomes; UP000235012; Unassembled WGS sequence.
Proteomes; UP000235045; Unassembled WGS sequence.
Proteomes; UP000235048; Unassembled WGS sequence.
Proteomes; UP000235102; Unassembled WGS sequence.
Proteomes; UP000235432; Unassembled WGS sequence.
Proteomes; UP000238028; Chromosome.
GO; GO:0034023; F:5-(carboxyamino)imidazole ribonucleotide mutase activity; IEA:UniProtKB-UniRule.
GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:UniProtKB-UniRule.
Gene3D; 3.40.50.7700; -; 1.
HAMAP; MF_01929; PurE_classI; 1.
InterPro; IPR033747; PurE_ClassI.
InterPro; IPR000031; PurE_dom.
InterPro; IPR024694; PurE_prokaryotes.
InterPro; IPR035893; PurE_sf.
Pfam; PF00731; AIRC; 1.
PIRSF; PIRSF001338; AIR_carboxylase; 1.
SMART; SM01001; AIRC; 1.
SUPFAM; SSF52255; SSF52255; 1.
TIGRFAMs; TIGR01162; purE; 1.
3: Inferred from homology;
Complete proteome {ECO:0000313|Proteomes:UP000031393,
ECO:0000313|Proteomes:UP000038546, ECO:0000313|Proteomes:UP000039153,
ECO:0000313|Proteomes:UP000039303};
Isomerase {ECO:0000256|HAMAP-Rule:MF_01929,
ECO:0000256|PIRNR:PIRNR001338, ECO:0000313|EMBL:CRH98750.1};
Lyase {ECO:0000313|EMBL:CRH98750.1};
Purine biosynthesis {ECO:0000256|HAMAP-Rule:MF_01929,
ECO:0000256|PIRNR:PIRNR001338}.
DOMAIN 3 154 AIRC. {ECO:0000259|SMART:SM01001}.
BINDING 11 11 Substrate. {ECO:0000256|HAMAP-
Rule:MF_01929,
ECO:0000256|PIRSR:PIRSR001338-1}.
BINDING 14 14 Substrate. {ECO:0000256|HAMAP-
Rule:MF_01929,
ECO:0000256|PIRSR:PIRSR001338-1}.
BINDING 41 41 Substrate. {ECO:0000256|HAMAP-
Rule:MF_01929,
ECO:0000256|PIRSR:PIRSR001338-1}.
SEQUENCE 162 AA; 16946 MW; C2215A67AC161395 CRC64;
MKPVISIIMG SKSDWATMQK TAEVLDRFGV AYEKKVVSAH RTPDLMFKHA EEARSRGIKI
IIAGAGGAAH LPGMVAAKTT LPVIGVPVKS RALSGVDSLY SIVQMPGGVP VATMAIGEAG
ATNAALFALR LLSVEDKSIA DALANFAEEQ GKIAEESSNE LI


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