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NADH-ubiquinone oxidoreductase chain 4L (EC 1.6.5.3)

 C1JZ86_ANISC            Unreviewed;        96 AA.
C1JZ86;
26-MAY-2009, integrated into UniProtKB/TrEMBL.
26-MAY-2009, sequence version 1.
07-JUN-2017, entry version 28.
RecName: Full=NADH-ubiquinone oxidoreductase chain 4L {ECO:0000256|RuleBase:RU004419};
EC=1.6.5.3 {ECO:0000256|RuleBase:RU004419};
Name=ND4L {ECO:0000313|EMBL:ACO58429.1};
Anilius scytale (Red pipe snake) (Coral cylinder snake).
Mitochondrion {ECO:0000313|EMBL:ACO58429.1}.
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata;
Toxicofera; Serpentes; Henophidia; Aniliidae; Anilius.
NCBI_TaxID=51844 {ECO:0000313|EMBL:ACO58429.1};
[1] {ECO:0000313|EMBL:ACO58429.1}
NUCLEOTIDE SEQUENCE.
PubMed=19416880; DOI=10.1073/pnas.0900233106;
Castoe T.A., de Koning A.P., Kim H.M., Gu W., Noonan B.P., Naylor G.,
Jiang Z.J., Parkinson C.L., Pollock D.D.;
"Evidence for an ancient adaptive episode of convergent molecular
evolution.";
Proc. Natl. Acad. Sci. U.S.A. 106:8986-8991(2009).
[2] {ECO:0000313|EMBL:ACO58429.1}
NUCLEOTIDE SEQUENCE.
Castoe T.;
Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Core subunit of the mitochondrial membrane respiratory
chain NADH dehydrogenase (Complex I) that is believed to belong to
the minimal assembly required for catalysis. Complex I functions
in the transfer of electrons from NADH to the respiratory chain.
The immediate electron acceptor for the enzyme is believed to be
ubiquinone. {ECO:0000256|RuleBase:RU004419}.
-!- CATALYTIC ACTIVITY: NADH + ubiquinone + 5 H(+)(In) = NAD(+) +
ubiquinol + 4 H(+)(Out). {ECO:0000256|RuleBase:RU004419}.
-!- SIMILARITY: Belongs to the complex I subunit 4L family.
{ECO:0000256|RuleBase:RU004419}.
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EMBL; FJ755180; ACO58429.1; -; Genomic_DNA.
RefSeq; YP_003795369.1; NC_014343.1.
GeneID; 9481028; -.
CTD; 4539; -.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
InterPro; IPR001133; NADH_UbQ_OxRdtase_chain4L/K.
PANTHER; PTHR11434; PTHR11434; 1.
3: Inferred from homology;
Membrane {ECO:0000256|SAM:Phobius};
Mitochondrion {ECO:0000256|RuleBase:RU004419,
ECO:0000313|EMBL:ACO58429.1}; NAD {ECO:0000256|RuleBase:RU004419};
Oxidoreductase {ECO:0000256|RuleBase:RU004419};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius};
Ubiquinone {ECO:0000256|RuleBase:RU004419}.
TRANSMEM 35 55 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 61 81 Helical. {ECO:0000256|SAM:Phobius}.
SEQUENCE 96 AA; 10612 MW; 1FF8788622877E93 CRC64;
MEMTQTALST MFLMSILGLS MQHKHLMLAL MSIEAMTLAI LMLLIMFTXI TQTLTQTPMP
IMLLTISVCE ASIGLTLVVA TTRTHGNDFL KNLTLL


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