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Nonstructural protein 5 (Fragment)

 Q67483_BANV             Unreviewed;       905 AA.
Q67483;
01-NOV-1996, integrated into UniProtKB/TrEMBL.
01-NOV-1996, sequence version 1.
20-JUN-2018, entry version 63.
SubName: Full=Nonstructural protein 5 {ECO:0000313|EMBL:AAA99481.1};
Flags: Fragment;
Name=NS5 {ECO:0000313|EMBL:AAA99481.1};
Banzi virus (BANV).
Viruses; ssRNA viruses; ssRNA positive-strand viruses, no DNA stage;
Flaviviridae; Flavivirus.
NCBI_TaxID=38837 {ECO:0000313|EMBL:AAA99481.1};
NCBI_TaxID=7157; Culicidae (mosquitos).
NCBI_TaxID=9606; Homo sapiens (Human).
NCBI_TaxID=9989; Rodentia.
[1] {ECO:0000313|EMBL:AAA99481.1}
NUCLEOTIDE SEQUENCE.
STRAIN=SAH 336 {ECO:0000313|EMBL:AAA99481.1};
PubMed=7561771;
Fulop L.D., Barrett A.D., Titball R.W.;
"Nucleotide sequence of the NS5 gene of Banzi virus: comparison with
other flaviviruses.";
J. Gen. Virol. 76:2317-2321(1995).
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EMBL; L40951; AAA99481.1; -; Genomic_RNA.
ProteinModelPortal; Q67483; -.
GO; GO:0005524; F:ATP binding; IEA:InterPro.
GO; GO:0004482; F:mRNA (guanine-N7-)-methyltransferase activity; IEA:InterPro.
GO; GO:0004483; F:mRNA (nucleoside-2'-O-)-methyltransferase activity; IEA:InterPro.
GO; GO:0003968; F:RNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
InterPro; IPR026490; mRNA_cap_0/1_MeTrfase.
InterPro; IPR000208; RNA-dir_pol_flavivirus.
InterPro; IPR007094; RNA-dir_pol_PSvirus.
InterPro; IPR002877; rRNA_MeTrfase_FtsJ_dom.
InterPro; IPR029063; SAM-dependent_MTases.
Pfam; PF00972; Flavi_NS5; 1.
Pfam; PF01728; FtsJ; 1.
SUPFAM; SSF53335; SSF53335; 1.
PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PROSITE; PS51591; RNA_CAP01_NS5_MT; 1.
4: Predicted;
DOMAIN 1 265 MRNA cap 0-1 NS5-type MT.
{ECO:0000259|PROSITE:PS51591}.
DOMAIN 529 681 RdRp catalytic.
{ECO:0000259|PROSITE:PS50507}.
NON_TER 1 1 {ECO:0000313|EMBL:AAA99481.1}.
SEQUENCE 905 AA; 102905 MW; 3EAF3C19280856C2 CRC64;
GGSSALTYGE VWKRQLNLLG KQEFMNYKVS DILEVDRSHA REVLNSGNDA VGVAVSRGSS
KLNWLIERGY LRPTGRVVDL GCGWGGWSYT CAAERQVTSV KAYTLGKEGH EKPRLIQSLG
WNIIKFKDKS DITRMTPHAS DTLLCDIGES SSNPEVEKER TLRVIEAVEK WMSPTTVSFC
FKVLAPYKPD VIEALERFQL KHGGGIIRNP YSRNSTHEMY YVSGVRNNIL HMVNSTSRML
MRRMSRPSGR STVVPDLIYP TGTRSVASEA GPLDLEKVKA RINRLKEEQE STWFVDSDHP
YRTWHYHGSY VAKQSGTAAS MINGVVKLLS GPWDRIEEVT NMAMTDTTPF GQQRVFKEKV
DTRAPEPPQG TREIMKVVNQ WLFDYLGRTK QPRICTKEEF INKVRSHAAL GGILTEQEGW
SSAAEAVADP RFWSLVDKER QAHLEGRCET CIYNMMGKRE KKPSEFGRAK GSRAIWYMWL
GARFLEFEAL GFLNEDHWLG RENSKAGVEG IGLQYLGYVV EEVARKGNGL VYADDTAGWD
TRITEADLED EQYIMKRMSA EHRQLAWAVM ELTYRNKVVK VPRPGPGGKI LMDVISRRDQ
RGSGQVVTYP LNTATNMKVQ LIRMAEAENV ITRNDVEKVS LITLKELQLW LEVNGVNRLE
RMAVSGDDCI VAPVDESFAG ALHHLNAMSK TRKDISEWEN SRGWTDWESV PFCSHHFHTL
YLKDGRTIIA PCRCQDELIG RARISPGNGW MIKETAGLSK AYAQMWTLMY FHRRDLRLMA
NAICSAVPID WVPTGRTTWS IHATGEWMSS DDMLEVWNKV WIQDNPHVKD KTPIFAWRDV
PYIQKGQDRA CGSLVGTSLR ASWAESIMTS VHRVRMLIGN ERYVNYMESM DRYATQRCSA
YGELL


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