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Notch 1

 W5P0Y6_SHEEP            Unreviewed;      2008 AA.
W5P0Y6;
16-APR-2014, integrated into UniProtKB/TrEMBL.
16-APR-2014, sequence version 1.
30-AUG-2017, entry version 31.
SubName: Full=Notch 1 {ECO:0000313|Ensembl:ENSOARP00000004085};
Name=NOTCH1 {ECO:0000313|Ensembl:ENSOARP00000004085};
Ovis aries (Sheep).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Caprinae; Ovis.
NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000004085, ECO:0000313|Proteomes:UP000002356};
[1] {ECO:0000313|Ensembl:ENSOARP00000004085, ECO:0000313|Proteomes:UP000002356}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000004085};
PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C.,
Wang J., Wang W., Xun X.;
"The sheep genome reference sequence: a work in progress.";
Anim. Genet. 41:449-453(2010).
[2] {ECO:0000313|Ensembl:ENSOARP00000004085}
IDENTIFICATION.
Ensembl;
Submitted (FEB-2014) to UniProtKB.
-!- CAUTION: Lacks conserved residue(s) required for the propagation
of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSOARP00000004085}.
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EMBL; AMGL01074391; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AMGL01074392; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AMGL01074393; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AMGL01074394; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AMGL01074395; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AMGL01074396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AMGL01074397; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AMGL01074398; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AMGL01074399; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AMGL01074400; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Ensembl; ENSOART00000004157; ENSOARP00000004085; ENSOARG00000003820.
GeneTree; ENSGT00810000125346; -.
OrthoDB; EOG091G01NU; -.
Proteomes; UP000002356; Chromosome 3.
GO; GO:0005912; C:adherens junction; IEA:Ensembl.
GO; GO:0016324; C:apical plasma membrane; IEA:Ensembl.
GO; GO:0009986; C:cell surface; IEA:Ensembl.
GO; GO:0031410; C:cytoplasmic vesicle; IEA:Ensembl.
GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
GO; GO:0002193; C:MAML1-RBP-Jkappa- ICN1 complex; IEA:Ensembl.
GO; GO:0005634; C:nucleus; IEA:Ensembl.
GO; GO:0043235; C:receptor complex; IEA:Ensembl.
GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
GO; GO:0001047; F:core promoter binding; IEA:Ensembl.
GO; GO:0019899; F:enzyme binding; IEA:Ensembl.
GO; GO:0004857; F:enzyme inhibitor activity; IEA:Ensembl.
GO; GO:0005112; F:Notch binding; IEA:Ensembl.
GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IEA:Ensembl.
GO; GO:0001190; F:transcriptional activator activity, RNA polymerase II transcription factor binding; IEA:Ensembl.
GO; GO:0003180; P:aortic valve morphogenesis; IEA:Ensembl.
GO; GO:1902263; P:apoptotic process involved in embryonic digit morphogenesis; IEA:Ensembl.
GO; GO:0060842; P:arterial endothelial cell differentiation; IEA:Ensembl.
GO; GO:0003162; P:atrioventricular node development; IEA:Ensembl.
GO; GO:0009912; P:auditory receptor cell fate commitment; IEA:Ensembl.
GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
GO; GO:0003214; P:cardiac left ventricle morphogenesis; IEA:Ensembl.
GO; GO:0060038; P:cardiac muscle cell proliferation; IEA:Ensembl.
GO; GO:0003213; P:cardiac right atrium morphogenesis; IEA:Ensembl.
GO; GO:0003219; P:cardiac right ventricle formation; IEA:Ensembl.
GO; GO:0060948; P:cardiac vascular smooth muscle cell development; IEA:Ensembl.
GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
GO; GO:0003273; P:cell migration involved in endocardial cushion formation; IEA:Ensembl.
GO; GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEA:Ensembl.
GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IEA:Ensembl.
GO; GO:0072044; P:collecting duct development; IEA:Ensembl.
GO; GO:0007386; P:compartment pattern specification; IEA:Ensembl.
GO; GO:0060982; P:coronary artery morphogenesis; IEA:Ensembl.
GO; GO:0003169; P:coronary vein morphogenesis; IEA:Ensembl.
GO; GO:0072017; P:distal tubule development; IEA:Ensembl.
GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
GO; GO:0060956; P:endocardial cell differentiation; IEA:Ensembl.
GO; GO:0003160; P:endocardium morphogenesis; IEA:Ensembl.
GO; GO:0007492; P:endoderm development; IEA:Ensembl.
GO; GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; IEA:Ensembl.
GO; GO:0030900; P:forebrain development; IEA:Ensembl.
GO; GO:0007440; P:foregut morphogenesis; IEA:Ensembl.
GO; GO:0010001; P:glial cell differentiation; IEA:Ensembl.
GO; GO:0072144; P:glomerular mesangial cell development; IEA:Ensembl.
GO; GO:0003241; P:growth involved in heart morphogenesis; IEA:Ensembl.
GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
GO; GO:0001947; P:heart looping; IEA:Ensembl.
GO; GO:0006959; P:humoral immune response; IEA:Ensembl.
GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
GO; GO:0002437; P:inflammatory response to antigenic stimulus; IEA:Ensembl.
GO; GO:0072602; P:interleukin-4 secretion; IEA:Ensembl.
GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
GO; GO:0070986; P:left/right axis specification; IEA:Ensembl.
GO; GO:0001889; P:liver development; IEA:Ensembl.
GO; GO:0030324; P:lung development; IEA:Ensembl.
GO; GO:0014031; P:mesenchymal cell development; IEA:Ensembl.
GO; GO:0003192; P:mitral valve formation; IEA:Ensembl.
GO; GO:2000811; P:negative regulation of anoikis; IEA:Ensembl.
GO; GO:0045608; P:negative regulation of auditory receptor cell differentiation; IEA:Ensembl.
GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
GO; GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IEA:Ensembl.
GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
GO; GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IEA:Ensembl.
GO; GO:0010812; P:negative regulation of cell-substrate adhesion; IEA:Ensembl.
GO; GO:2001027; P:negative regulation of endothelial cell chemotaxis; IEA:Ensembl.
GO; GO:0060253; P:negative regulation of glial cell proliferation; IEA:Ensembl.
GO; GO:0045662; P:negative regulation of myoblast differentiation; IEA:Ensembl.
GO; GO:0010832; P:negative regulation of myotube differentiation; IEA:Ensembl.
GO; GO:0048715; P:negative regulation of oligodendrocyte differentiation; IEA:Ensembl.
GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
GO; GO:0046533; P:negative regulation of photoreceptor cell differentiation; IEA:Ensembl.
GO; GO:2000974; P:negative regulation of pro-B cell differentiation; IEA:Ensembl.
GO; GO:2000737; P:negative regulation of stem cell differentiation; IEA:Ensembl.
GO; GO:0021915; P:neural tube development; IEA:Ensembl.
GO; GO:0097150; P:neuronal stem cell population maintenance; IEA:Ensembl.
GO; GO:0003270; P:Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation; IEA:Ensembl.
GO; GO:0003344; P:pericardium morphogenesis; IEA:Ensembl.
GO; GO:1903849; P:positive regulation of aorta morphogenesis; IEA:Ensembl.
GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
GO; GO:0048711; P:positive regulation of astrocyte differentiation; IEA:Ensembl.
GO; GO:0030513; P:positive regulation of BMP signaling pathway; IEA:Ensembl.
GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IEA:Ensembl.
GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IEA:Ensembl.
GO; GO:0046427; P:positive regulation of JAK-STAT cascade; IEA:Ensembl.
GO; GO:0045618; P:positive regulation of keratinocyte differentiation; IEA:Ensembl.
GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
GO; GO:0061419; P:positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; IEA:Ensembl.
GO; GO:0007221; P:positive regulation of transcription of Notch receptor target; IEA:Ensembl.
GO; GO:0045070; P:positive regulation of viral genome replication; IEA:Ensembl.
GO; GO:0060740; P:prostate gland epithelium morphogenesis; IEA:Ensembl.
GO; GO:0003184; P:pulmonary valve morphogenesis; IEA:Ensembl.
GO; GO:0060768; P:regulation of epithelial cell proliferation involved in prostate gland development; IEA:Ensembl.
GO; GO:1901201; P:regulation of extracellular matrix assembly; IEA:Ensembl.
GO; GO:0014807; P:regulation of somitogenesis; IEA:Ensembl.
GO; GO:0003256; P:regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; IEA:Ensembl.
GO; GO:0032495; P:response to muramyl dipeptide; IEA:Ensembl.
GO; GO:0060528; P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; IEA:Ensembl.
GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
GO; GO:0048103; P:somatic stem cell division; IEA:Ensembl.
GO; GO:0002040; P:sprouting angiogenesis; IEA:Ensembl.
GO; GO:0035148; P:tube formation; IEA:Ensembl.
GO; GO:0060979; P:vasculogenesis involved in coronary vascular morphogenesis; IEA:Ensembl.
GO; GO:0060843; P:venous endothelial cell differentiation; IEA:Ensembl.
GO; GO:0060412; P:ventricular septum morphogenesis; IEA:Ensembl.
GO; GO:0003222; P:ventricular trabecula myocardium morphogenesis; IEA:Ensembl.
CDD; cd00204; ANK; 1.
Gene3D; 1.25.40.20; -; 1.
InterPro; IPR002110; Ankyrin_rpt.
InterPro; IPR020683; Ankyrin_rpt-contain_dom.
InterPro; IPR024600; DUF3454_notch.
InterPro; IPR001881; EGF-like_Ca-bd_dom.
InterPro; IPR013032; EGF-like_CS.
InterPro; IPR000742; EGF-like_dom.
InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
InterPro; IPR018097; EGF_Ca-bd_CS.
InterPro; IPR009030; Growth_fac_rcpt_.
InterPro; IPR008297; Notch.
Pfam; PF11936; DUF3454; 1.
Pfam; PF00008; EGF; 18.
Pfam; PF12661; hEGF; 1.
PIRSF; PIRSF002279; Notch; 4.
SMART; SM00248; ANK; 1.
SMART; SM01334; DUF3454; 1.
SMART; SM00181; EGF; 21.
SMART; SM00179; EGF_CA; 21.
SUPFAM; SSF48403; SSF48403; 1.
SUPFAM; SSF57184; SSF57184; 2.
PROSITE; PS50297; ANK_REP_REGION; 1.
PROSITE; PS50088; ANK_REPEAT; 1.
PROSITE; PS00010; ASX_HYDROXYL; 15.
PROSITE; PS00022; EGF_1; 18.
PROSITE; PS01186; EGF_2; 18.
PROSITE; PS50026; EGF_3; 22.
PROSITE; PS01187; EGF_CA; 7.
4: Predicted;
ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
Calcium {ECO:0000256|PIRSR:PIRSR002279-1};
Complete proteome {ECO:0000313|Proteomes:UP000002356};
Disulfide bond {ECO:0000256|PIRSR:PIRSR002279-2, ECO:0000256|PROSITE-
ProRule:PRU00076, ECO:0000256|SAAS:SAAS00601599};
EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076,
ECO:0000256|SAAS:SAAS00032677};
Metal-binding {ECO:0000256|PIRSR:PIRSR002279-1};
Reference proteome {ECO:0000313|Proteomes:UP000002356};
Repeat {ECO:0000256|SAAS:SAAS00594563}.
DOMAIN 11 47 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 137 173 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 244 282 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 317 355 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 357 393 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 395 431 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 433 468 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 470 506 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 508 543 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 545 581 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 583 618 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 620 656 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 658 698 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 775 812 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 814 850 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 852 888 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 889 922 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 924 960 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 971 1008 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 1010 1046 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 1048 1084 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 1093 1130 EGF-like. {ECO:0000259|PROSITE:PS50026}.
DOMAIN 1565 1618 ANK_REP_REGION.
{ECO:0000259|PROSITE:PS50297}.
REPEAT 1565 1597 ANK. {ECO:0000256|PROSITE-
ProRule:PRU00023}.
METAL 336 336 Calcium 2.
{ECO:0000256|PIRSR:PIRSR002279-1}.
METAL 337 337 Calcium 2; via carbonyl oxygen.
{ECO:0000256|PIRSR:PIRSR002279-1}.
METAL 357 357 Calcium 3.
{ECO:0000256|PIRSR:PIRSR002279-1}.
METAL 358 358 Calcium 3; via carbonyl oxygen.
{ECO:0000256|PIRSR:PIRSR002279-1}.
METAL 360 360 Calcium 3.
{ECO:0000256|PIRSR:PIRSR002279-1}.
METAL 374 374 Calcium 3.
{ECO:0000256|PIRSR:PIRSR002279-1}.
METAL 375 375 Calcium 3; via carbonyl oxygen.
{ECO:0000256|PIRSR:PIRSR002279-1}.
DISULFID 37 46 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 253 270 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 272 281 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 328 343 {ECO:0000256|PIRSR:PIRSR002279-2}.
DISULFID 345 354 {ECO:0000256|PIRSR:PIRSR002279-2,
ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 361 372 {ECO:0000256|PIRSR:PIRSR002279-2}.
DISULFID 366 381 {ECO:0000256|PIRSR:PIRSR002279-2}.
DISULFID 383 392 {ECO:0000256|PIRSR:PIRSR002279-2,
ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 421 430 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 437 447 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 458 467 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 512 522 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 533 542 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 571 580 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 587 597 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 608 617 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 646 655 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 802 811 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 840 849 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 878 887 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 912 921 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 950 959 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 998 1007 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 1036 1045 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 1074 1083 {ECO:0000256|PROSITE-ProRule:PRU00076}.
DISULFID 1120 1129 {ECO:0000256|PROSITE-ProRule:PRU00076}.
SEQUENCE 2008 AA; 209782 MW; D66B74A2B4C7278A CRC64;
PPAPPGKTCQ QADPCASNPC ANGGQCLPFE ASYICHCPPG FHGPTCRQDV GGGGGAAEVG
RAGGGEGEGG GLPPCLRLCF WEVWGPHLHT HPTPDYLPGS LCLPAPVPCE GAPRPSAAPS
NGVSTAARFT GQNCEENIDD CPGNSCKNGG ACVAGVTPYN CRCPPEWTGV HSGRRRGHLC
PWSLSPWGAG RREEGCCDLQ LTAPLPGSEA PPKPPGAAQT WVAPXGVRLP RCPLPPCPGL
LCHLNDACIS NPCNEGANCD TNPVNGKAIC TCPSGYTGPA CSQDVDECSL GTGSQGAGEP
VGSRPMGGGG SDGGGRHTPA CSRGSNPCQN DATCLDQIGE FQCICMPGYE GLHCEVNTDE
CASSPCLQNG RCLDKINEFV CECPTGFTGH LCQYDVDECA STPCKNGAKC LDGPNTYSCM
CTEGYTGPHC EVDIDECDPD PCHYGSCKDG VATFSCLCQP GYTGHHCETN INECHSQPCR
HGGSCRMSEQ ERVTSSGLPP PGPNCEINLD DCASNPCDSG TCLDKIDGYE CACEPGYTGS
MCNINIDECA DSPCHNGGTC EDGINGFTCR CPEGYHDPTC LSEVNECSSN PCIHGACRDS
LNGYKCDCDP GWSGANCDVN NDECESNPCV NGGACKDMTS GYVCACREGF SGPNCQTNIN
ECASNPCLNQ GTCIDDVAGY KCNCLLPYTG MGGAWGCELG AWRAGAGPGQ VGGLAGGGGP
GSWCPAVCPR PRPPRRATRC ALMVEPPVDG GCRGLCQDLP GALASGRGSR RAHHSASPSQ
ETDPCHNGGS CTDGINTAFC DCLPGFQGAF CEEDINECAS SPCRNGANCT DCVDGYTCTC
PTGFSGIHCE NNTPDCTESS CFNGGTCVDG INSFTCLCPP GFTGSYCQHC DSRPCLHGGT
CQDSYGAYKC SCPQGYTGLN CQTLVRWCDS SPCKNGGRCW QTNALYRCEC HSGWAGPFCD
VPSVSSAVAP PEQSVNVTHL CRNGGLCMNA GNTHHCHCQA GYTGSYCEEQ VDECSPSPCQ
NGATCTDYPG GYSCECVPGY HGVNCSEEVN ECLSQPCRHG GTCIDLTNTY KCSCPRGTQG
VHCEINVDDC NPPIDPVSRG PKCFNNGTCV DQVGGYSCTC PPGFVGERCE GDVNECLSNP
CDARGTPACQ PLTCLPTSDL LADPCPALCS PRRQVRPALG SRGEQCGGCC RAAEERGQQG
HAEQQGGLAG ETLPLSHSFP TGGPPSHDLS FGPRLPNPLS PRRSCGKTET WVLVWLALPA
SLWGHTPPPP GSRARAAAAV HPPPCHCDLR PHLYPWLSLA GTGQMVHAEP RGWWAGWGVL
RCQAPRWNGE CPPSTRGPPL VSLSLAAICP QSLSMLFLSC PVSCACLWAP VSPDPPLPSL
TPEGISYSGG GAQGMLLGPV TSVCHGAEAS SRLLLGRQGD WRQGPPGRGG RGRQRHRWAR
QTPPTQTPSS LTPHSSLGGA YVACPLYRPT DAHRHTLVTP QPLKLWQGLH LCGFGGGEGG
THSNIGSHRS SGWVLEDAFK VFLFVRRNSD GRTLGGELRV EAGSGVEAGL TAGPSAAPAP
ICSPQEETPL FLAAREGSYE TAKVLLDHFA NRDITDHMDR LPRDIAQERM HHDIVRLLDE
YSLVRSPPLH GATLGGAPTL SPPLCSPNGY LGNLKPPMQG KKARKPSTKG LACGGKEPKD
LKARRKKSQD GKGCLLDSGS VLSPVDSLES PHGYLGGSRL AFEAGPPRLS HLPVASSTST
ILGAGGSGGG GAVNFTVGGA AGLNGQCEWL SRLQNGLVPN QYNPLRGGVT PGTLSTQAAG
LQHGTVGPLH APALSQVMSY QALPNTRLAS QPHLVQTQQL QPQQNLQMQP PSMPPQPNLQ
PPQPHLGVSS AASGHLGRSF LGGELSQADM QPLGPGNLAA HTVLPQDGQV LPTSLPSTLA
PPTLAPPMTT AQFLTPPSQH SYSSSPVDNT PSHQLQVPEH PFLTPSPESP DQWSSSSPHS
NISDWSEGIS SPPTSVPSQI AHVPEAFK


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MCA2410PE MOUSE ANTI MOUSE NOTCH 1 RPE, Product Type Monoclonal Antibody, Specificity NOTCH 1, Target Species Mouse, Host Mouse, Format RPE, Isotypes IgG1, Applications F*, Clone mN1A 100 TESTS
SCH-MCA2410PET MOUSE ANTI MOUSE NOTCH 1 RPE, Product Type Monoclonal Antibody, Specificity NOTCH 1, Target Species Mouse, Host Mouse, Format RPE, Isotypes IgG1, Applications F*, Clone mN1A 25 TESTS
SCH-MCA2410PE MOUSE ANTI MOUSE NOTCH 1 RPE, Product Type Monoclonal Antibody, Specificity NOTCH 1, Target Species Mouse, Host Mouse, Format RPE, Isotypes IgG1, Applications F*, Clone mN1A 100 TESTS
MCA2410PET MOUSE ANTI MOUSE NOTCH 1 RPE, Product Type Monoclonal Antibody, Specificity NOTCH 1, Target Species Mouse, Host Mouse, Format RPE, Isotypes IgG1, Applications F*, Clone mN1A 25 TESTS
MCA5704 HAMSTER ANTI MOUSE NOTCH 4, Product Type Monoclonal Antibody, Specificity NOTCH 4, Target Species Mouse, Host Hamster, Format Purified, Isotypes IgG, Applications F, Clone HMN4_14 0.25 mg
MCA5704GA HAMSTER ANTI MOUSE NOTCH 4, Product Type Monoclonal Antibody, Specificity NOTCH 4, Target Species Mouse, Host Hamster, Format Purified, Isotypes IgG, Applications F, Clone HMN4_14 0.1 mg
MCA2410 MOUSE ANTI MOUSE NOTCH 1, Product Type Monoclonal Antibody, Specificity NOTCH 1, Target Species Mouse, Host Mouse, Format Purified, Isotypes IgG1, Applications C, F*, WB, Clone mN1A 0.25 mg


 

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