Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Nucleoprotein (Nucleocapsid protein) (NP) (Protein N)

 NCAP_PI3H4              Reviewed;         515 AA.
P06159; Q81075;
01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
01-JAN-1988, sequence version 1.
28-FEB-2018, entry version 70.
RecName: Full=Nucleoprotein;
AltName: Full=Nucleocapsid protein;
Short=NP;
Short=Protein N;
Name=N; Synonyms=NP;
Human parainfluenza 3 virus (strain Wash/47885/57) (HPIV-3) (Human
parainfluenza 3 virus (strain NIH 47885)).
Viruses; ssRNA viruses; ssRNA negative-strand viruses;
Mononegavirales; Paramyxoviridae; Respirovirus.
NCBI_TaxID=11217;
NCBI_TaxID=9606; Homo sapiens (Human).
[1]
NUCLEOTIDE SEQUENCE [GENOMIC RNA].
PubMed=2878059; DOI=10.1099/0022-1317-67-11-2543;
Jambou R.C., Elango N., Venkatesan S., Collins P.L.;
"Complete sequence of the major nucleocapsid protein gene of human
parainfluenza type 3 virus: comparison with other negative strand
viruses.";
J. Gen. Virol. 67:2543-2548(1986).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC RNA].
PubMed=3012866; DOI=10.1016/0042-6822(86)90382-X;
Sanchez A., Banerjee A.K., Furuichi Y., Richardson M.A.;
"Conserved structures among the nucleocapsid proteins of the
paramyxoviridae: complete nucleotide sequence of human parainfluenza
virus type 3 NP mRNA.";
Virology 152:171-180(1986).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC RNA / MRNA].
STRAIN=Isolate 104B44;
PubMed=2418584; DOI=10.1016/0042-6822(86)90116-9;
Galinski M.S., Mink M.A., Lambert D.M., Wechsler S.L., Pons M.W.;
"Molecular cloning and sequence analysis of the human parainfluenza 3
virus RNA encoding the nucleocapsid protein.";
Virology 149:139-151(1986).
[4]
NUCLEOTIDE SEQUENCE [GENOMIC RNA].
STRAIN=JS;
PubMed=8266719; DOI=10.1016/0168-1702(93)90014-E;
Stokes A., Tierney E.L., Sarris C.M., Murphy B.R., Hall S.L.;
"The complete nucleotide sequence of two cold-adapted, temperature-
sensitive attenuated mutant vaccine viruses (cp12 and cp45) derived
from the JS strain of human parainfluenza virus type 3 (PIV3).";
Virus Res. 30:43-52(1993).
[5]
RNA-BINDING.
STRAIN=JS;
PubMed=9234948; DOI=10.1006/viro.1997.8633;
Durbin A.P., Siew J.W., Murphy B.R., Collins P.L.;
"Minimum protein requirements for transcription and RNA replication of
a minigenome of human parainfluenza virus type 3 and evaluation of the
rule of six.";
Virology 234:74-83(1997).
-!- FUNCTION: Encapsidates the genome in a ratio of 1 N per 6
ribonucleotides, protecting it from nucleases. The nucleocapsid
(NC) has a helical structure. The encapsidated genomic RNA is
termed the NC and serves as template for transcription and
replication. During replication, encapsidation by N is coupled to
RNA synthesis and all replicative products are resistant to
nucleases (By similarity). {ECO:0000250}.
-!- SUBUNIT: Homomultimerizes to form the nucleocapsid. Binds to viral
genomic RNA. In nucleocapsid, binds the P protein and thereby
positions the polymerase on the template (By similarity).
{ECO:0000250}.
-!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Host cytoplasm.
-!- DOMAIN: Ncore is globular and carries regions required for N self-
assembly and RNA-binding. Ntail is an intrinsically disordered
monomeric domain (By similarity). {ECO:0000250}.
-!- SIMILARITY: Belongs to the paramyxoviruses nucleocapsid family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; D10025; BAA00915.1; -; mRNA.
EMBL; X04612; CAA28282.1; -; Genomic_RNA.
EMBL; M11849; AAA46863.1; -; Genomic_RNA.
EMBL; M14552; AAA46864.1; -; Genomic_RNA.
EMBL; U51116; AAB48684.1; -; Genomic_RNA.
PIR; A24285; VHNZP3.
DIP; DIP-1086N; -.
GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW.
GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-KW.
GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
InterPro; IPR002021; Paramyx_ncap.
Pfam; PF00973; Paramyxo_ncap; 1.
1: Evidence at protein level;
Capsid protein; Helical capsid protein; Host cytoplasm;
Ribonucleoprotein; RNA-binding; Viral nucleoprotein; Virion.
CHAIN 1 515 Nucleoprotein.
/FTId=PRO_0000142667.
REGION 1 400 Ncore. {ECO:0000250}.
REGION 401 515 Ntail. {ECO:0000250}.
VARIANT 45 45 N -> D (in strain: Isolate 104B44).
VARIANT 104 104 E -> R (in strain: JS).
VARIANT 129 129 E -> D (in strain: JS).
VARIANT 284 284 T -> S (in strain: Isolate 104B44).
VARIANT 389 389 A -> S (in strain: JS).
VARIANT 436 436 D -> N (in strain: JS).
VARIANT 457 457 R -> Q (in strain: JS).
VARIANT 489 489 G -> S (in strain: JS).
VARIANT 493 493 S -> P (in strain: JS).
SEQUENCE 515 AA; 57827 MW; 438044FE092A6271 CRC64;
MLSLFDTFNA RRQENITKSA GGAIIPGQKN TVSIFALGPT ITDDNEKMTL ALLFLSHSLD
NEKQHAQRAG FLVSLLSMAY ANPELYLTTN GSNADVKYVI YMIEKDLKRQ KYGGFVVKTR
EMIYEKTTEW IFGSDLDYDQ ETMLQNGRNN STIEDLVHTF GYPSCLGALI IQIWIVLVKA
ITSISGLRKG FFTRLEAFRQ DGTVQAGLVL SGDTVDQIGS IMRSQQSLVT LMVETLITMN
TSRNDLTTIE KNIQIVGNYI RDAGLASFFN TIRYGIETRM AALTLSTLRP DINRLKALME
LYLSKGPRAP FICILRDPIH GEFAPGNYPA IWSYAMGVAV VQNRAMQQYV TGRSYLDIDM
FQLGQAVARD AEAQMSSTLE DELGVTHEAK ESLKRHIRNI NSSETSFHKP TGGSAIEMAI
DEEPEQFEHR ADQEQDGEPQ SSIIQYAWAE GNRSDDRTEQ ATESDNIKTE QQNIRDRLNK
RLNDKKKQGS QPSTNPTNRT NQDEIDDLFN AFGSN


Related products :

Catalog number Product name Quantity
SCH-OBT1905X RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa1_49), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , Applicat 1 mg
SCH-OBT1906X RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa1_49 192_220), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , 1 mg
OBT1906X RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa1_49 192_220), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , 1 mg
OBT1906 RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa1_49 192_220), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , 0.1 mg
OBT1905X RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa1_49), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , Applicat 1 mg
SCH-OBT1906 RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa1_49 192_220), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , 0.1 mg
OBT1904X RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa340_390), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , Appli 1 mg
SCH-OBT1904X RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa340_390), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , Appli 1 mg
orb81559 Hepatitis Virus Nucleocapsid (core) Genotype-3a protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. The protein is fused to GST 100
orb81556 Hepatitis Virus Nucleocapsid (core) Genotype-1b protein The E.coli derived recombinant multimer protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. The protein is fus 100
orb81557 Hepatitis Virus Nucleocapsid (core) Genotype-2a protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. The protein is fused to GST 100
orb81558 Hepatitis Virus Nucleocapsid (core) Genotype-2b protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. The protein is fused to GST 100
orb81561 Hepatitis Virus Nucleocapsid (core) Genotype-4 protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. The protein is fused to GST 100
orb81567 Hepatitis Virus Nucleocapsid (core) (105-302) protein The E.coli derived recombinant protein from E1 region contains the HCV core nucleocapsid immunodominant regions, amino acids 105-302. The protein 100
orb81769 Measles Virus Nucleocapsid protein The E.coli derived recombinant protein contains the nucleocapsid immunodominant regions, 89-165 amino acids. For research use only. 100
orb81568 Hepatitis Virus Nucleocapsid (core) 24 protein The HCV Core 24 genotype-1b, E.coli derived recombinant protein, contains the HCV core nucleocapsid immunodominant regions. The protein is fused with b-g 100
orb81570 Hepatitis Virus Nucleocapsid (core) 22kDa protein The E.coli derived recombinant protein contains the HCV core nucleocapsid genotype 1b, immunodominant regions, amino acids 2-192, 22kDa.The protein is 100
orb81638 Hantavirus protein The Hantavirus nucleocapsid (N) fusion protein protein is expressed in E.coli and fused to GST-tag having Mw of 37 kDa. Hantavirus nucleocapsid (N) is conserved among different stra 100
orb81555 Hepatitis Virus Nucleocapsid (core) Genotype-1a protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. For research use only. 100
orb81563 Hepatitis Virus Nucleocapsid (core) Genotype-6a protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. For research use only. 100
orb81554 Hepatitis Virus Nucleocapsid (core) Genotype-1 protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 1-102. For research use only. 100
orb81560 Hepatitis Virus Nucleocapsid (core) Genotype-3b protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. For research use only. 100
orb81562 Hepatitis Virus Nucleocapsid (core) Genotype-5 protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. For research use only. 100
orb81564 Hepatitis Virus Nucleocapsid (core) Genotype-3_10 protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. For research use only. 100
orb81572 Hepatitis Virus Nucleocapsid (core) 22kDa, Fluorescein Labeled protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-192. The Fluoresc 100


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur