Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Nucleoprotein (Nucleocapsid protein) (NP) (Protein N)

 NCAP_PI2HT              Reviewed;         542 AA.
P21737;
01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
01-MAY-1991, sequence version 1.
18-JUL-2018, entry version 80.
RecName: Full=Nucleoprotein;
AltName: Full=Nucleocapsid protein;
Short=NP;
Short=Protein N;
Name=N; Synonyms=NP;
Human parainfluenza 2 virus (strain Toshiba) (HPIV-2).
Viruses; ssRNA viruses; ssRNA negative-strand viruses;
Mononegavirales; Paramyxoviridae; Rubulavirus.
NCBI_TaxID=11214;
NCBI_TaxID=9606; Homo sapiens (Human).
[1]
NUCLEOTIDE SEQUENCE [MRNA].
PubMed=2173261; DOI=10.1016/0042-6822(90)90145-H;
Yuasa T., Bando H., Kawano M., Tsurudome M., Nishio M., Kondo K.,
Komada H., Ito Y.;
"Sequence analyses of the 3' genome end and NP gene of human
parainfluenza type 2 virus: sequence variation of the gene-starting
signal and the conserved 3' end.";
Virology 179:777-784(1990).
[2]
INTERACTION WITH P PROTEIN.
PubMed=8887478; DOI=10.1099/0022-1317-77-10-2457;
Nishio M., Tsurudome M., Kawano M., Watanabe N., Ohgimoto S., Ito M.,
Komada H., Ito Y.;
"Interaction between nucleocapsid protein (NP) and phosphoprotein (P)
of human parainfluenza virus type 2: one of the two NP binding sites
on P is essential for granule formation.";
J. Gen. Virol. 77:2457-2463(1996).
[3]
HOMOMULTIMERIZATION.
PubMed=10466799; DOI=10.1099/0022-1317-80-8-2017;
Nishio M., Tsurudome M., Ito M., Kawano M., Kusagawa S., Komada H.,
Ito Y.;
"Mapping of domains on the human parainfluenza virus type 2
nucleocapsid protein (NP) required for NP-phosphoprotein or NP-NP
interaction.";
J. Gen. Virol. 80:2017-2022(1999).
-!- FUNCTION: Encapsidates the genome, protecting it from nucleases.
The nucleocapsid (NC) has a helical structure. The encapsidated
genomic RNA is termed the NC and serves as template for
transcription and replication. During replication, encapsidation
by N is coupled to RNA synthesis and all replicative products are
resistant to nucleases (By similarity). {ECO:0000250}.
-!- SUBUNIT: Homomultimerizes to form the nucleocapsid. Binds to viral
genomic RNA. In nucleocapsid, binds the P protein and thereby
positions the polymerase on the template.
-!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Host cytoplasm.
-!- DOMAIN: Ncore is globular and carries regions required for N self-
assembly and RNA-binding. Ntail is an intrinsically disordered
monomeric domain (By similarity). {ECO:0000250}.
-!- SIMILARITY: Belongs to the paramyxoviruses nucleocapsid family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; M55320; AAA46865.1; -; mRNA.
EMBL; X57559; CAA40783.1; -; Genomic_RNA.
PIR; A36420; VHNZP2.
ProteinModelPortal; P21737; -.
SMR; P21737; -.
KEGG; vg:935191; -.
OrthoDB; VOG090000BV; -.
Proteomes; UP000000472; Genome.
GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW.
GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-KW.
GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
InterPro; IPR002021; Paramyx_ncap.
Pfam; PF00973; Paramyxo_ncap; 1.
1: Evidence at protein level;
Capsid protein; Complete proteome; Helical capsid protein;
Host cytoplasm; Reference proteome; Ribonucleoprotein; RNA-binding;
Viral nucleoprotein; Virion.
CHAIN 1 542 Nucleoprotein.
/FTId=PRO_0000142670.
REGION 1 400 Ncore. {ECO:0000250}.
REGION 1 294 Homomultimerization.
REGION 295 402 P protein-binding 1.
REGION 401 542 Ntail. {ECO:0000250}.
REGION 403 494 P protein-binding 2.
SEQUENCE 542 AA; 61121 MW; AB9F6636497045FF CRC64;
MSSVLKTFER FTIQQELQEQ SDDTPVPLET IKPTIRVFVI NNNDPVVRSR LLFFNLRIIM
SNTAREGHRA GALLSLLSLP SAAMSNHIKL AMHSPEASID RVEITGFENN SFRVIPDARS
TMSRGEVLAF EALAEDIPDT LNHQTPFVNN DVEDDIFDET EKFLDVCYSV LMQAWIVTCK
CMTAPDQPPV SVAKMAKYQQ QGRINARYVL QPEAQRLIQN AIRKSMVVRH FMTYELQLSQ
SRSLLANRYY AMVGDIGKYI EHSGMGGFFL TLKYGLGTRW PTLALAAFSG ELQKLKALML
HYQSLGPMAK YMALLESPKL MDFVPSEYPL DYSYAMGIGT VLDTNMRNYA YGRSYLNQQY
FQLGVETARK QQGAVDNRTA EDLGMTAADK ADLTATISKL SLSQLPRGRQ PISDPFAGAN
DREMGGQAND TPVYNFNPID TRRYDNYDSD GEDRIDNDQD QAIRENRGEP GQPNNQTSDN
QQRFNPPIPQ RTSGMSSEEF QHSMNQYIRA MHEQYRGSQD DDANDATDGN DISLELVGDF
DS


Related products :

Catalog number Product name Quantity
SCH-OBT1905X RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa1_49), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , Applicat 1 mg
SCH-OBT1906X RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa1_49 192_220), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , 1 mg
OBT1906X RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa1_49 192_220), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , 1 mg
OBT1906 RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa1_49 192_220), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , 0.1 mg
OBT1905X RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa1_49), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , Applicat 1 mg
SCH-OBT1906 RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa1_49 192_220), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , 0.1 mg
OBT1904X RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa340_390), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , Appli 1 mg
SCH-OBT1904X RECOMBINANT SARS NUCLEOCAPSID PROTEIN (aa340_390), Product Type Recombinant Protein, Specificity SARS NUCLEOCAPSID PROTEIN , Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , Appli 1 mg
orb81559 Hepatitis Virus Nucleocapsid (core) Genotype-3a protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. The protein is fused to GST 100
orb81556 Hepatitis Virus Nucleocapsid (core) Genotype-1b protein The E.coli derived recombinant multimer protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. The protein is fus 100
orb81557 Hepatitis Virus Nucleocapsid (core) Genotype-2a protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. The protein is fused to GST 100
orb81558 Hepatitis Virus Nucleocapsid (core) Genotype-2b protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. The protein is fused to GST 100
orb81561 Hepatitis Virus Nucleocapsid (core) Genotype-4 protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. The protein is fused to GST 100
orb81567 Hepatitis Virus Nucleocapsid (core) (105-302) protein The E.coli derived recombinant protein from E1 region contains the HCV core nucleocapsid immunodominant regions, amino acids 105-302. The protein 100
orb81769 Measles Virus Nucleocapsid protein The E.coli derived recombinant protein contains the nucleocapsid immunodominant regions, 89-165 amino acids. For research use only. 100
orb81568 Hepatitis Virus Nucleocapsid (core) 24 protein The HCV Core 24 genotype-1b, E.coli derived recombinant protein, contains the HCV core nucleocapsid immunodominant regions. The protein is fused with b-g 100
orb81570 Hepatitis Virus Nucleocapsid (core) 22kDa protein The E.coli derived recombinant protein contains the HCV core nucleocapsid genotype 1b, immunodominant regions, amino acids 2-192, 22kDa.The protein is 100
orb81638 Hantavirus protein The Hantavirus nucleocapsid (N) fusion protein protein is expressed in E.coli and fused to GST-tag having Mw of 37 kDa. Hantavirus nucleocapsid (N) is conserved among different stra 100
orb81555 Hepatitis Virus Nucleocapsid (core) Genotype-1a protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. For research use only. 100
orb81563 Hepatitis Virus Nucleocapsid (core) Genotype-6a protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. For research use only. 100
orb81554 Hepatitis Virus Nucleocapsid (core) Genotype-1 protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 1-102. For research use only. 100
orb81560 Hepatitis Virus Nucleocapsid (core) Genotype-3b protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. For research use only. 100
orb81562 Hepatitis Virus Nucleocapsid (core) Genotype-5 protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. For research use only. 100
orb81564 Hepatitis Virus Nucleocapsid (core) Genotype-3_10 protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-119. For research use only. 100
orb81572 Hepatitis Virus Nucleocapsid (core) 22kDa, Fluorescein Labeled protein The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-192. The Fluoresc 100


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur