Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Oligodendrocyte transcription factor 1 (Oligo1) (Oligodendrocyte-specific bHLH transcription factor 1)

 OLIG1_MOUSE             Reviewed;         260 AA.
Q9JKN5;
30-AUG-2002, integrated into UniProtKB/Swiss-Prot.
30-AUG-2002, sequence version 2.
25-OCT-2017, entry version 121.
RecName: Full=Oligodendrocyte transcription factor 1;
Short=Oligo1;
AltName: Full=Oligodendrocyte-specific bHLH transcription factor 1;
Name=Olig1;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
STRAIN=Swiss Webster; TISSUE=Embryo;
PubMed=11091082; DOI=10.1016/S0925-4773(00)00466-4;
Takebayashi H., Yoshida S., Sugimori M., Kosako H., Kominami R.,
Nakafuku M., Nabeshima Y.;
"Dynamic expression of basic helix-loop-helix Olig family members:
implication of Olig2 in neuron and oligodendrocyte differentiation and
identification of a new member, Olig3.";
Mech. Dev. 99:143-148(2000).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Olfactory epithelium;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 17-260, AND DEVELOPMENTAL STAGE.
PubMed=10719889; DOI=10.1016/S0896-6273(00)80898-3;
Zhou Q., Wang S., Anderson D.J.;
"Identification of a novel family of oligodendrocyte lineage-specific
basic helix-loop-helix transcription factors.";
Neuron 25:331-343(2000).
[4]
INDUCTION BY SHH.
PubMed=10719888; DOI=10.1016/S0896-6273(00)80897-1;
Lu Q.R., Yuk D.-I., Alberta J.A., Zhu Z., Pawlitzky I., Chan J.A.,
McMahon A.P., Stiles C.D., Rowitch D.H.;
"Sonic hedgehog-regulated oligodendrocyte lineage genes encoding bHLH
proteins in the mammalian central nervous system.";
Neuron 25:317-329(2000).
[5]
FUNCTION.
PubMed=11955448; DOI=10.1016/S0092-8674(02)00678-5;
Lu Q.R., Sun T., Zhu Z., Ma N., Garcia M., Stiles C.D., Rowitch D.H.;
"Common developmental requirement for Olig function indicates a motor
neuron/oligodendrocyte connection.";
Cell 109:75-86(2002).
-!- FUNCTION: Promotes formation and maturation of oligodendrocytes,
especially within the brain. Cooperates with OLIG2 to establish
the pMN domain of the embryonic neural tube.
{ECO:0000269|PubMed:11955448}.
-!- INTERACTION:
P41136:Id2; NbExp=5; IntAct=EBI-1213712, EBI-309167;
P41139:Id4; NbExp=5; IntAct=EBI-1213712, EBI-1213725;
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-
ProRule:PRU00981}.
-!- TISSUE SPECIFICITY: Expressed specifically in brain.
{ECO:0000269|PubMed:11091082}.
-!- DEVELOPMENTAL STAGE: Expressed in the ventral spinal cord as early
as 9.5 dpc. Expression declines to undetectable levels by 10.5 dpc
and reappears in a narrow zone within the ventral neuroepithelium
of the spinal cord. In the 14.5 dpc spinal cord, expressed in the
oligodendrocyte progenitors of the ventral ventricular zone, but
not dorsal root ganglia Schwann cells. Also expressed scattered in
the mantle zone, likely corresponding to oligodendrocyte
progenitors migrating out from their site of origin. By 15.5 dpc,
dispersed throughout the gray matter, with little or no residual
expression in the ventricular zone. In the postnatal brain,
present preferentially in the white matter, such as corpus
callosum and cerebellar medulla. Expressed in the olfactory
epithelium from 11.5dpc onward. {ECO:0000269|PubMed:10719889}.
-!- INDUCTION: By SHH. {ECO:0000269|PubMed:10719888}.
-!- SEQUENCE CAUTION:
Sequence=BAB18906.1; Type=Erroneous initiation; Evidence={ECO:0000305};
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AB038696; BAB18906.1; ALT_INIT; mRNA.
EMBL; BC046316; AAH46316.1; -; mRNA.
EMBL; AF232928; AAF61721.1; -; Genomic_DNA.
CCDS; CCDS28324.1; -.
RefSeq; NP_058664.2; NM_016968.4.
UniGene; Mm.39300; -.
ProteinModelPortal; Q9JKN5; -.
SMR; Q9JKN5; -.
BioGrid; 206153; 5.
IntAct; Q9JKN5; 5.
MINT; MINT-7295439; -.
STRING; 10090.ENSMUSP00000061408; -.
iPTMnet; Q9JKN5; -.
PhosphoSitePlus; Q9JKN5; -.
PaxDb; Q9JKN5; -.
PRIDE; Q9JKN5; -.
Ensembl; ENSMUST00000056882; ENSMUSP00000061408; ENSMUSG00000046160.
GeneID; 50914; -.
KEGG; mmu:50914; -.
UCSC; uc007zxf.1; mouse.
CTD; 116448; -.
MGI; MGI:1355334; Olig1.
eggNOG; KOG3898; Eukaryota.
eggNOG; ENOG4111U26; LUCA.
GeneTree; ENSGT00530000063239; -.
HOGENOM; HOG000015810; -.
HOVERGEN; HBG053369; -.
InParanoid; Q9JKN5; -.
KO; K09085; -.
OMA; GTMLRPQ; -.
OrthoDB; EOG091G0IHI; -.
PhylomeDB; Q9JKN5; -.
TreeFam; TF322733; -.
PRO; PR:Q9JKN5; -.
Proteomes; UP000000589; Chromosome 16.
Bgee; ENSMUSG00000046160; -.
CleanEx; MM_OLIG1; -.
ExpressionAtlas; Q9JKN5; baseline and differential.
Genevisible; Q9JKN5; MM.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0005667; C:transcription factor complex; ISS:MGI.
GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; ISS:MGI.
GO; GO:0048663; P:neuron fate commitment; IMP:MGI.
GO; GO:0048709; P:oligodendrocyte differentiation; IEA:InterPro.
GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:MGI.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
CDD; cd00083; HLH; 1.
Gene3D; 4.10.280.10; -; 1.
InterPro; IPR011598; bHLH_dom.
InterPro; IPR036638; HLH_DNA-bd_sf.
InterPro; IPR032657; Olig1.
PANTHER; PTHR19290:SF7; PTHR19290:SF7; 1.
Pfam; PF00010; HLH; 1.
SMART; SM00353; HLH; 1.
SUPFAM; SSF47459; SSF47459; 1.
PROSITE; PS50888; BHLH; 1.
1: Evidence at protein level;
Complete proteome; Developmental protein; DNA-binding; Nucleus;
Reference proteome; Transcription; Transcription regulation.
CHAIN 1 260 Oligodendrocyte transcription factor 1.
/FTId=PRO_0000127412.
DOMAIN 94 153 bHLH. {ECO:0000255|PROSITE-
ProRule:PRU00981}.
COMPBIAS 44 52 Poly-Ser.
COMPBIAS 90 94 Poly-Gln.
SEQUENCE 260 AA; 27141 MW; 5EA8A74D9DF0D310 CRC64;
MYYAISQARV NAAPATMLRP QRPGDVQLGA SLYELVGYRQ PPISSSSSSS SSTASLLPKP
AREKAEAPLA EPRGPAPESG GARADAKEEQ QQQQLRRKIN SRERKRMQDL NLAMDALREV
ILPYSAAHCQ GAPGRKLSKI ATLLLARNYI LLLGSSLQEL RRALGDGAGP AAPRLLLAGL
PLLAAAPGSV LLAPGAVGPP ETLRPTKYLS LALDEPPCGQ FSLPAGGAGS PGLCSCAVCK
FPHLVPAGLG LAAVQAQFSK


Related products :

Catalog number Product name Quantity
EIAAB28822 Mouse,Mus musculus,Olig1,Oligo1,Oligodendrocyte transcription factor 1,Oligodendrocyte-specific bHLH transcription factor 1
EIAAB28823 Olg-1 bHLH protein,Olig1,Oligo1,Oligodendrocyte transcription factor 1,Rat,Rattus norvegicus
EIAAB28827 bHLHb7,Bhlhb7,Class B basic helix-loop-helix protein 7,Mouse,Mus musculus,Olig3,Oligo3,Oligodendrocyte transcription factor 3,Oligodendrocyte-specific bHLH transcription factor 3
EIAAB32964 bHLH transcription factor p48,Mouse,Mus musculus,p48 DNA-binding subunit of transcription factor PTF1,Pancreas transcription factor 1 subunit alpha,Pancreas-specific transcription factor 1a,Ptf1a,Ptf1
EIAAB32963 bHLH transcription factor p48,p48 DNA-binding subunit of transcription factor PTF1,Pancreas transcription factor 1 subunit alpha,Pancreas-specific transcription factor 1a,Ptf1a,Ptf1p48,PTF1-p48,Rat,Ra
18-003-42089 Pancreas transcription factor 1 subunit alpha - Pancreas-specific transcription factor 1a; bHLH transcription factor p48; p48 DNA-binding subunit of transcription factor PTF1; PTF1-p48 Polyclonal 0.1 mg Protein A
28-767 Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation.TWIST1 is a bHLH transcription factor and shares similarity with another bHLH 0.1 mg
27-359 TCFL5 is a new bHLH transcription factor that negatively regulates upstream transcription factor-dependent transcription. 0.05 mg
EIAAB42103 Immunoglobulin enhancer-binding factor E12_E47,Pan,Pancreas specific transcription factor 1c,Ptf1c,Rat,Rattus norvegicus,Tcf3,TCF-3,Tcfe2a,Transcription factor 3,Transcription factor E2-alpha,Transcri
E02O0030 Rat Oligodendrocyte transcription factor 1 ELISA 96T/kit
OLIG3 OLIG1 Gene oligodendrocyte transcription factor 1
E0060b Chicken ELISA Kit FOR Oligodendrocyte transcription factor 2 96T
E04O0030 Rabbit Oligodendrocyte transcription factor 1 ELISA 96T/kit
E06O0030 Goat Oligodendrocyte transcription factor 1 ELISA 96T/kit
E07O0030 Porcine Oligodendrocyte transcription factor 1 ELISA 96T/kit
E03O0030 Mouse Oligodendrocyte transcription factor 1 ELISA 96T/kit
E09O0030 Monkey Oligodendrocyte transcription factor 1 ELISA 96T/kit
E01O0030 Human Oligodendrocyte transcription factor 1 ELISA 96T/kit
E05O0030 Guinea Pig Oligodendrocyte transcription factor 1 ELISA 96T/kit
E13365h Human Oligodendrocyte Transcription Factor 3 ELISA 96T
OMA1 OLIG3 Gene oligodendrocyte transcription factor 3
CSB-EL016328RA Rat Oligodendrocyte transcription factor 1(OLIG1) ELISA kit 96T
E12037h Human Oligodendrocyte Transcription Factor 1 ELISA 96T
ASF1A_BOVIN Chicken ELISA Kit FOR Oligodendrocyte transcription factor 2 96T
E11O0030 Bovine Oligodendrocyte transcription factor 1 ELISA 96T/kit


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur